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*  CFU-GEMM
IL-3 and GM-CSF as single factors are equally active in stimulating CFU-GEMM, but the combination of both factors produces ... "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte. The common myeloid progenitor (CMP) and the common lymphoid ... CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are the multipotential progenitor cells for ... The growth of CFU-GEMM is stimulated by the stem cell factor, or SCF. SCF has been found also to synergize with GM-CSF, IL-6, ...
*  Neutropenia
... granulocyte-colony stimulating factor (G-CSF) or granulocyte-macrophage colony-stimulating factor (GM-CSF). These are cytokines ... Recombinant granulocyte-colony stimulating factor preparations, such as filgrastim can be effective in patients with congenital ... These factors are used regularly in cancer treatment with adults and children. The factors promote neutrophil recovery ... Neutropenia can be treated with hematopoietic Growth Factors, ...
*  Autoimmune neutropenia
... antibiotics to prevent infection and granulocyte colony-stimulating factor (G-CSF) to temporarily increase neutrophil counts. ... In some cases, tests for granulocyte-specific antibodies need to be repeated several times before a positive result is seen. ... is typically normal or it can show increased cell production with a variably diminished number of segmented granulocytes. s ... granulocytes, segmented neutrophils, segs, polysegmented neutrophils, polys). These antibodies destroy granulocytic neutrophils ...
*  Granulocyte-macrophage colony-stimulating factor receptor
... is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells. The ... The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), ... Lia F, Rajotte D, Clark SC, Hoang T (Nov 1996). "A dominant negative granulocyte-macrophage colony-stimulating factor receptor ... Doyle SE, Gasson JC (Aug 1998). "Characterization of the role of the human granulocyte-macrophage colony-stimulating factor ...
*  Granulocyte colony-stimulating factor
"Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by ... Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein ... Duarte RF, Franf DA (June 2002). "The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF ... "The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors". Proceedings of the ...
*  Granulocyte colony-stimulating factor receptor
The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein ... "Entrez Gene: CSF3R colony stimulating factor 3 receptor (granulocyte)". Mehta, H M; Futami, M; Glaubach, T; Lee, D W; Andolina ... G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a ... Granulocyte colony-stimulating factor receptor has been shown to interact with Grb2, HCK and SHC1. Cluster of differentiation ...
*  Granulocyte-macrophage colony-stimulating factor
CFU-GM Granulocyte-macrophage colony-stimulating factor receptor Filgrastim (Neupogen, a granulocyte colony-stimulating factor ... "Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: comparisons and potential for use ... Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric ... "Granulocyte-macrophage colony-stimulating factor: not just another haematopoietic growth factor". Medical Oncology. 31 (1): 774 ...
*  Kostmann syndrome
This type is refractory to granulocyte colony-stimulating factor. There is an absence of lysosomes in fibroblasts and depletion ... Neutropenia Granulocyte colony-stimulating factor Klein, Christoph (2011). "Genetic Defects in Severe Congenital Neutropenia: ... Most cases of SCN respond to treatment with granulocyte colony-stimulating factor (filgrastim), which increases the neutrophil ... Over 90% of SCN responds to treatment with granulocyte colony-stimulating factor (filgrastim), which has significantly improved ...
*  Large-cell lung carcinoma with rhabdoid phenotype
"Lung large cell carcinoma producing granulocyte-colony-stimulating factor". Ann. Thorac. Surg. 83 (1): 308-10. doi:10.1016/j. ... including neuroendocrine tumor-related products and granulocyte-macrophage colony stimulating factor (GM-CSF). Vimentin, an ... Interestingly, expression of thyroid transcription factor-1 (TTF-1), a commonly used marker for primary lung cancers, appears ... There have also been reports of rhabdoid carcinomas expressing vascular endothelial growth factor (VEGF), suggesting that ...
*  Morning pseudoneutropenia
"Circadian variation of granulocyte colony stimulating factor levels in man". British Journal of Haematology. 106 (2): 368-70. ... of circulating white blood cells and changes in the levels of hematopoietic cytokines and granulocyte colony stimulating factor ... GCSF). Antipsychotics may amplify the natural variation in these hematopoietic factors. Neutropenia is a hematological disorder ...
*  Filgrastim
The gene for human granulocyte colony-stimulating factor is inserted into the genetic material of Escherichia coli. The G-CSF ... Filgrastim is a human granulocyte colony stimulating factor (G-CSF) produced by recombinant DNA technology. G-CSF regulates the ... NEUPOGEN (filgrastim) is the name for recombinant methionyl human granulocyte colony stimulating factor (r-metHuG-CSF). It is ... Filgrastim is similar to naturally occurring granulocyte colony-stimulating factor (G-CSF). Filgrastim was approved for medical ...
*  Interleukin
These include granulocyte colony-stimulating factor (GCSF) and myelomonocytic growth factor (MGF). GCSF acts in hematopoiesis ... Secondary structure analysis has suggested similarity to IL4 and granulocyte-macrophage colony stimulating factor (GMCSF). ... "Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor". Archives of ... "Characterization of a human multilineage-colony-stimulating factor cDNA clone identified by a conserved noncoding sequence in ...
*  Shigekazu Nagata
Nagata identified Interferon in 1980 and Granulocyte colony-stimulating factor in 1986. He also identified a death factor (Fas ... "Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor". Nature. 319 (6052): 415-8. doi: ... a novel member of the tumor necrosis factor family". Cell. 75 (6): 1169-78. doi:10.1016/0092-8674(93)90326-L. PMID 7505205. " ...
*  CD34
"CD34 expression by murine hematopoietic stem cells mobilized by granulocyte colony-stimulating factor". Blood. 96 (5): 1989-93 ... in a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells ... Kees UR, Ford J (Feb 1999). "Synergistic action of stem-cell factor and interleukin-7 in a human immature T-cell line". ... which are factor XIIIa-negative) in the interstitium and around the adnexa of dermis of skin, as well as cells in soft tissue ...
*  Thiamazole
Administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) may increase recovery. Other known side ...
*  Lenograstim
... is a recombinant granulocyte colony-stimulating factor which functions as an immunostimulator. It is developed by ...
*  FCGR1A
... in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy". Blood. 82 (3): 931-9 ...
*  Amgen
PEG Granulocyte-Colony Stimulating Factor or "Pegfilgrastim") (for neutropenia) Neupogen (Granulocyte-Colony Stimulating Factor ... "Prophylactic granulocyte colony-stimulating factor in patients receiving dose-intensive cancer chemotherapy: a meta-analysis". ... a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases. Other products ... the first rheumatoid arthritis drug targeting tumor necrosis factor alpha (TNF-alpha). A 2006 assessment by the National ...
*  Shwachman-Diamond syndrome
Neutropenia may be treated with granulocyte-colony stimulating factor (GCSF) to boost peripheral neutrophil counts. However, ...
*  Peripheral stem cell transplantation
Granulocyte colony stimulating factor (GCSF) are naturally occurring glycoproteins that stimulate white blood cell ...
*  Bone marrow suppression
"Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner". Blood. 109 (8): ... In-vitro colony forming cell (CFC) assays using normal human bone marrow grown in appropriate semi-solid media such as ...
*  Glycogen storage disease type I
Granulocyte colony-stimulating factor (G-CSF, e.g. filgrastim) therapy can reduce the risk of infection. Impaired platelet ... Increased purine catabolism is an additional contributing factor. Uric acid levels of 6-12 mg/dl are typical of GSD I. ... There is some evidence that metabolic control of the disease is a factor. Impaired gluconeogenesis results in elevations of ...
*  FLAG (chemotherapy)
Granulocyte colony-stimulating factor (G-CSF): a glycoprotein that shortens the duration and severity of neutropenia. FLAG and ...
*  Pegfilgrastim
... is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. It ... serves to stimulate the level of white blood cells (neutrophils). Pegfilgrastim treatment can be used to stimulate bone marrow ...
*  GRB2
Granulocyte colony-stimulating factor receptor, HER2/neu, HNRNPC, Huntingtin, INPP5D, IRS1, ITK, Janus kinase 1, Janus kinase 2 ... Saleem A, Kharbanda S, Yuan ZM, Kufe D (May 1995). "Monocyte colony-stimulating factor stimulates binding of ... SHP-2 and p40 to the murine granulocyte colony-stimulating factor receptor". Biochimica et Biophysica Acta. 1448 (1): 70-6. doi ... which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl". ...
*  GeoVax
... a novel vaccine product developed by GeoVax scientists that expresses human granulocyte-macrophage colony stimulating factor ( ... by stimulating an infected individual's immune system to resist the progression of infection. The study is being completed at ...
*  PTPN11
SHP-2 and p40 to the murine granulocyte colony-stimulating factor receptor". Biochim. Biophys. Acta. 1448 (1): 70-6. doi: ... PTPN11 has been shown to interact with CagA, Cbl gene, CD117, CD31, CEACAM1, Epidermal growth factor receptor, Erk FRS2, GAB1, ... Wong L, Johnson GR (Aug 1996). "Epidermal growth factor induces coupling of protein-tyrosine phosphatase 1D to GRB2 via the ... CagA is a protein and virulence factor inserted by Helicobacter pylori into gastric epithelia. Once activated by SRC ...