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*  Goblet cell
... mucus of goblet cells in blue Goblet cells in large intestine The main role of goblet cells is to secrete mucus in order to ... Goblet cells are simple columnar epithelial cells that secrete gel-forming mucins, like mucin MUC5AC. The goblet cells mainly ... more pale cells. An intestinal gland from the human intestine with goblet cells visible Goblet cell in ileum Section of mouse ... In mucicarmine stains, deep red mucin is found within goblet cell bodies. Goblet cells can be seen in the examples below as the ...
*  Goblet cell carcinoid
The goblet cell carcinoid, abbreviated GCC and also known as crypt cell carcinoma and neuroendocrine tumour with goblet cell ... They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear ... December 2007). "Goblet cell carcinoid of the appendix: a specific type of carcinoma". Histopathology. 51 (6): 763-73. doi: ... histologically arising from Paneth cells. GCCs may present as appendicitis. GCCs are diagnosed by pathology. ...
*  Simple columnar epithelium
e. Goblet cells. f. Leucocytes in epithelium. f'. Leucocytes below epithelium. g. Bloodvessels. h. Muscle cells cut across. ... These viruses may kill the ciliated cells or stop the cilia beating. In either case, mucus builds up and forms a good site for ... A ciliated columnar epithelium lines the lumen of the uterine tube, where currents generated by the cilia propel the egg cell ...
*  Gastrointestinal wall
... is a glandular epithelium with many goblet cells. Goblet cells secrete mucus, which lubricates the passage of food along and ... Goblet cells, which secrete mucous, are also present. The appendix has a mucosa resembling the colon but is heavily infiltrated ... Activity is initiated by the pacemaker cells (interstitial cells of Cajal). The gut has intrinsic peristaltic activity (basal ... Each cell also has microvilli. it is organised into plicae circulares and villi, and the enterocytes have microvilli. This ...
*  Ileum
... goblet cells, which secrete mucin, a substance that lubricates the wall of the organ; Paneth cells, most common in the terminal ... Goblet cells in the wall of an ileum vili. At its sides, enterocytes are visible over a core of lamina propria. Cross section ... microfold cells, which take up and transport antigens from the lumen to lymphatic cells of the lamina propria; and ... Cells in the lining of the ileum secrete the protease and carbohydrase enzymes responsible for the final stages of protein and ...
*  Interleukin 13
Mast cell, Basophil cells, Eosinophil cells and Nuocyte cells. Interleukin-13 is a central regulator in IgE synthesis, goblet ... Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is a gel-like mucin product of goblet cells. Interleukin-13 induces ... Most normal cells, such as immune cells or endothelial cells, express very low or undetectable levels of IL-13 receptors. ... IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, Natural killer T cell, ...
*  Mucous gland
Most are multicellular, but goblet cells are single-celled glands. The mucous salivary glands are similar in structure to the ...
*  Mannan oligosaccharide-based nutritional supplements
This mucus is produced in specific cells called goblet cells. In general the number of goblet cells is an indicator of mucus ... Researchers found that goblet cell numbers were increased with MOS. The importance of those changes for animal health is still ... In the yeast cell wall, mannan oligosaccharides are present in complex molecules that are linked to the protein moiety. There ... They can be attached to the cell wall proteins as part of -O and -N glycosyl groups and also constitute elements of large α-D- ...
*  Guttural pouch
The epithelium is pseudostratified and ciliated containing mucous-secreting goblet cells; lymph nodules are also present. The ...
*  Nasal concha
The respiratory epithelium is partially composed of mucus-producing goblet cells. This secreted mucus covers the nasal cavities ...
*  Alkaliphilus
"Nonrandom distribution of goblet cells around the circumference of colonic crypt". Cell and Tissue Research. 160 (4): 551-6. ...
*  SPDEF
2007). "SPDEF regulates goblet cell hyperplasia in the airway epithelium". J. Clin. Invest. 117 (4): 978-88. doi:10.1172/ ... Needed for the differentiation of both pulmonary and intestinal goblet cells GRCh38: Ensembl release 89: ENSG00000124664 - ... PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator ... 2003). "p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells". Oncogene. 22 ...
*  Gene silencing
COPD is characterized by goblet cell hyperplasia and mucus hypersecretion. Mucus secretion was found to be reduced when the ... For instance, mice implanted with colon adenocarcinoma cells were found to survive longer when the cells were pretreated with ... from binding to the cancer cells. Cleaving the fusion protein reduced the amount of transformed hematopoietic cells that spread ... Viral genes and host genes that are required for viruses to replicate or enter the cell, or that play an important role in the ...
*  Schneiderian membrane
Microscopically there is a pseudostratified columnar ciliated epithelium that includes goblet cells. This membrane is present ...
*  Trefoil factor 1
... new mucus-associated secretory products of conjunctival goblet cells". Adv. Exp. Med. Biol. 506 (Pt A): 313-6. PMID 12613926. ... Mori K, Fujii R, Kida N, Ohta M, Hayashi K (1988). "Identification of a polypeptide secreted by human breast cancer cells (MCF- ... Cell. 98 (5): 675-86. doi:10.1016/S0092-8674(00)80054-9. PMID 10490106. Newton JL, Allen A, Westley BR, May FE (2000). "The ... "Cloning of a gene expressed in human breast cancer and regulated by estrogen in MCF-7 cells". DNA. 4 (1): 11-21. doi:10.1089/ ...
*  Neuroendocrine tumor
... such as goblet cell cancer, a rare gastrointestinal tract tumor. Placing a given tumor into one of categories depends on well- ... together with nearby cells, are damaged by the attached radiation. Not all cells are immediately killed; cell death can go on ... small-cell lung cancer (SCLC) large cell neuroendocrine carcinoma of the lung (LCNEC) Extrapulmonary small cell carcinomas ( ... "Goblet cell carcinoid of the appendix: A specific type of carcinoma". Histopathology. 51 (6): 763-73. doi:10.1111/j.1365- ...
*  Trefoil factor 3
Goblet cell-specific expression of a peptide targeted for apical secretion". J. Biol. Chem. 268 (9): 6694-702. PMID 8454642. ... This gene is a marker of columnar epithelium and is expressed in a variety of tissues including goblet cells of the intestines ... 2003). "Ocular TFF-peptides: new mucus-associated secretory products of conjunctival goblet cells". Adv. Exp. Med. Biol. 506 ( ... Cell Genet. 72 (4): 299-302. doi:10.1159/000134208. PMID 8641134. Chinery R, Williamson J, Poulsom R (1997). "The gene encoding ...
*  Trefoil factor 2
2003). "Ocular TFF-peptides: new mucus-associated secretory products of conjunctival goblet cells". Adv. Exp. Med. Biol. 506 ( ...
*  SCIN
2005). "Barrier role of actin filaments in regulated mucin secretion from airway goblet cells". Am. J. Physiol., Cell Physiol. ... During cell stimulation, Calcium channels open allowing calcium ions to enter de secretory cell. Increase in intracellualr ... Cell Biol. 6 (2): 97-105. doi:10.1038/ncb1086. PMID 14743216. Ehre C, Rossi AH, Abdullah LH, et al. ( ... Rodríguez Del Castillo A; Vitale ML; Trifaró JM (1992). "Ca2+ and pH determine the interaction of chromaffin cell scinderin ...
*  Trachea
The epithelium contains goblet cells, which are glandular, modified simple columnar epithelial cells that produce mucins, the ... It is lined with an epithelium that has goblet cells which produce protective mucins. An inflammatory condition, also involving ... Mucus lines the ciliated cells of the trachea to trap inhaled foreign particles that the cilia then waft upward toward the ... The smallest tubes, tracheoles, penetrate cells[citation needed] and serve as sites of diffusion for water, oxygen, and carbon ...
*  FOXJ1
"Goblet cells are derived from a FOXJ1-expressing progenitor in a human airway epithelium". American Journal of Respiratory Cell ... The onset of FOXJ1 expression is indicative of cells fated to become motile cilliated cells. Cells commit towards ciliogenesis ... "Forkhead box J1 expression is upregulated and correlated with prognosis in patients with clear cell renal cell carcinoma". ... "Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells". Journal of Cell Science. 117 ...
*  List of intestinal epithelial differentiation genes
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Exp Cell ... Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell ... Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature. 2005 ... "Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells". Biochemical ...
*  Gland
Mucous glands secrete a viscous product, rich in carbohydrates (such as glycoproteins), e.g. goblet cells. Sebaceous glands ... goblet cells, salivary gland, tear gland, intestinal glands. The type of secretory product of exocrine glands may also be one ... Merocrine glands cells secrete their substances by exocytosis (e.g., mucous and serous glands). Also called "eccrine". e.g. max ... As growth proceeds, the column of cells may divide or give off offshoots, in which case a compound gland is formed. In many ...
*  Transcytosis
Listeria monocytogenes has been shown to enter the intestinal lumen via transcytosis across goblet cells. Shiga toxin secreted ... Macromolecules are captured in vesicles on one side of the cell, drawn across the cell, and ejected on the other side. Examples ... "Transcytosis of Listeria monocytogenes across the intestinal barrier upon specific targeting of goblet cell accessible E- ... invade and translocate across both cultured human intestinal epithelial cells and human brain microvascular endothelial cells ...
*  Acute bronchitis
Further obstruction to the airways is caused by more goblet cells in the small airways. This is typical of chronic bronchitis. ... A blood test would indicate inflammation (as indicated by a raised white blood cell count and elevated C-reactive protein). An ... A sputum sample showing neutrophil granulocytes (inflammatory white blood cells) and culture showing that has pathogenic ... oral whole cell nontypeable Haemophilus influenzae vaccine may protect against the disease, but "the evidence is mixed". Most ...
*  Hook (Once Upon a Time)
He is the first to drink from the goblet holding a sleeping curse that will break Snow and Charming's curse set by the Evil ... However, Hook manages to work his way free in time to stop David from killing George in his cell. Afterward, Hook receives ...