In humans the relevant genes are called GLUD1 (glutamate dehydrogenase 1) and GLUD2 (glutamate dehydrogenase 2), and there are ... L-Glutamate Dehydrogenase, in The Enzymes, Vol VII. Academic Press. pp. 3-24. Frieden C (May 1965). "Glutamate Dehydrogenase. ... as glutamate dehydrogenase equilibrium favours the production of ammonia and α-ketoglutarate. Glutamate dehydrogenase also has ... glutamate dehydrogenase enzymes are divided into the following three classes:[citation needed] EC 1.4.1.2: L-glutamate + H2O + ...

... glutamic acid dehydrogenase, L-glutamate dehydrogenase, L-glutamic acid dehydrogenase, NAD(P)+-glutamate dehydrogenase, NAD(P)H ... Glutamate dehydrogenase (NADP+) (EC 1.4.1.4, glutamic dehydrogenase, dehydrogenase, glutamate (nicotinamide adenine ... glutamate dehydrogenase, glutamate dehydrogenase (NADP+)) is an enzyme with systematic name L-glutamate:NADP+ oxidoreductase ( ... Smith, E.L.; Austen, B.M.; Blumenthal, K.M.; Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. (ed.). The Enzymes. ...

GLUD1 (glutamate dehydrogenase 1) is a mitochondrial matrix enzyme, one of the family of glutamate dehydrogenases that are ... "Entrez Gene: glutamate dehydrogenase 1". Won JG, Tseng HS, Yang AH, Tang KT, Jap TS, Lee CH, Lin HD, Burcus N, Pittenger G, ... Smith TJ, Schmidt T, Fang J, Wu J, Siuzdak G, Stanley CA (May 2002). "The structure of apo human glutamate dehydrogenase ... GeneReviews/NCBI/NIH/UW entry on Familial Hyperinsulinism Glutamate+dehydrogenase at the U.S. National Library of Medicine ...

Glutamate dehydrogenase (NAD(P)+) (EC 1.4.1.3, glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+]) is an enzyme with ... Smith, E.L.; Austen, B.M.; Blumenthal, K.M.; Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. (ed.). The Enzymes. ... Glutamate+dehydrogenase+(NAD(P)+) at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology v t ... Strecker HJ (September 1953). "Glutamic dehydrogenase". Archives of Biochemistry and Biophysics. 46 (1): 128-40. doi:10.1016/ ...

... glutamate semialdehyde dehydrogenase, and glutamate-gamma-semialdehyde dehydrogenase. This enzyme participates in urea cycle ... a glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) is an enzyme that catalyzes the chemical reaction L-glutamate 5- ... The systematic name of this enzyme class is L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating). Other names in ... Baich A (July 1971). "The biosynthesis of proline in Escherichia coli: phosphate-dependent glutamate -semialdehyde ...

... glutamate forming), aminoadipic semialdehyde synthase, saccharopine dehydrogenase (NAD+, L-glutamate-forming), 6-N-(L-1,3- ... In enzymology, a saccharopine dehydrogenase (NAD+, L-glutamate-forming) (EC 1.5.1.9) is an enzyme that catalyzes the chemical ... glutamate-forming), saccharopin dehydrogenase, NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and, ... The systematic name of this enzyme class is N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). ...

... glutamate-forming) dehydrogenase, aminoadipic semialdehyde-glutamic reductase, aminoadipate semialdehyde-glutamate reductase, ... In enzymology, a saccharopine dehydrogenase (NADP+, L-glutamate-forming) (EC 1.5.1.10) is an enzyme that catalyzes the chemical ... 3. Aminoadipic semialdehyde-glutamate reductase". J. Biol. Chem. 241 (14): 3430-4. PMID 4380448. Portal: Biology v t e (EC 1.5. ... The systematic name of this enzyme class is N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming). ...

This dehydrogenase is one of the family of glutamate dehydrogenases that are ubiquitous in life. Glutamate dehydrogenase 2 is ... Glutamate dehydrogenase 2, mitochondrial, also known as GDH 2, is an enzyme that in humans is encoded by the GLUD2 gene. ... "Entrez Gene: glutamate dehydrogenase 2". Shashidharan P, Michaelidis TM, Robakis NK, Kresovali A, Papamatheakis J, Plaitakis A ... Spanaki C, Zaganas I, Kleopa KA, Plaitakis A (2010). "Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular ...

Colman, Roberta (1986). "Glutamate Dehydrogenase: Function of Molecular Topology". National Institute of Diabetes and Digestive ...

Glutamate dehydrogenase pseudogene 5, also known as GLUDP5, is a human gene. "Human PubMed Reference:". National Center for ... Julliard JH, Smith EL (1979). "Partial amino acid sequence of the glutamate dehydrogenase of human liver and a revision of the ... "Entrez Gene: GLUDP5 glutamate dehydrogenase pseudogene 5". Meissner T, Beinbrech B, Mayatepek E (1999). "Congenital ... 1993). "Structure and expression analysis of a member of the human glutamate dehydrogenase (GLUD) gene family mapped to ...

Glutamate dehydrogenase provides an oxidizable carbon source used for the production of energy as well as a reduced electron ... Werner C, Stubbs MT, Krauth-Siegel RL, Klebe G (2005). "The crystal structure of Plasmodium falciparum glutamate dehydrogenase ... 1986). "Antibodies to the glutamate dehydrogenase of Plasmodium falciparum" (PDF). Parasitology. 92 (2): 313-324. doi:10.1017/ ... The first malaria antigen suitable as target for such a test was a soluble glycolytic enzyme Glutamate dehydrogenase. None of ...

... allosterically inhibits aspartate kinase and glutamate dehydrogenase. Glutamate dehydrogenase reversibly converts ... Akai S, Ikushiro H, Sawai T, Yano T, Kamiya N, Miyahara I (February 2019). "The crystal structure of homoserine dehydrogenase ... By the action of homoserine dehydrogenases, the semialdehyde is converted to homoserine. L-Homoserine is substrate for ... Threonine acts as another allosteric inhibitor of aspartate kinase and homoserine dehydrogenase, but it is a competitive ...

Ling IT, Cooksley S, Bates PA, Hempelmann E, Wilson RJ (1986). "Antibodies to the glutamate dehydrogenase of Plasmodium ... Consequences included natural selection for sickle-cell disease, thalassaemias, glucose-6-phosphate dehydrogenase deficiency, ... and glucose-6-phosphate dehydrogenase deficiency) were present in the Mediterranean world by the time of the Roman Empire, ...

Robinson, Sharon A.; Stewart, George R.; Phillips, Richard (1992). "Regulation of glutamate dehydrogenase activity in relation ... "The Role of Glutamate Dehydrogenase in Plant Nitrogen Metabolism". Plant Physiology. 95 (2): 509-516. doi:10.1104/pp.95.2.509. ... An early career highlights was demonstrating a role for the enzyme glutamate dehydrogenase in nitrogen mobilisation. Some of ... "The role of glutamate dehydrogenase in plant nitrogen metabolism". Plant Physiology. 95 (2): 509-516. doi:10.1104/pp.95.2.509. ...

HI/HA is caused by increased Glutamate dehydrogenase 1 (GDH) activity due to the presence of overactivating point mutations in ... Smith, Hong Q.; Smith, Thomas J. (2016). "Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase". ...

Ling I.T.; Cooksley S.; Bates P.A.; Hempelmann E.; Wilson R.J.M. (1986). "Antibodies to the glutamate dehydrogenase of ... The first rapid diagnostic tests were using Plasmodium glutamate dehydrogenase as antigen. PGluDH was soon replaced by ... "Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT) for the detection of malaria". Transact Royal Soc Trop ... Plasmodium lactate dehydrogenase (pLDH). Depending on which monoclonal antibodies are used, this type of assay can distinguish ...

Sanner, T. (1975-11-18). "Formation of transient complexes in the glutamate dehydrogenase catalyzed reaction". Biochemistry. 14 ...

1986). "Antibodies to the glutamate dehydrogenase of Plasmodium falciparum" (PDF). Parasitology. 92 (2): 313-324. doi:10.1017/ ...

1986). "Antibodies to the glutamate dehydrogenase of Plasmodium falciparum" (PDF). Parasitology. 92 (2): 313-324. doi:10.1017/ ...

These liver enzymes included lactate dehydrogenase and glutamate pyruvate transaminase. Although they were described as having ... These transformations are catalyzed by 5α- and 5β-reductase and 3α- and 3β-hydroxysteroid dehydrogenase both in the liver and ... The enzymes involved in these metabolic processes are 5α- and 5β-reductase as well as 3α- and 3β-hydroxysteroid dehydrogenase ( ... 3β-Hydroxysteroid dehydrogenase inhibitors, 5α-Reductase inhibitors, Alkene derivatives, Androgens and anabolic steroids, ...

Frieden, C; Colman, R F (1967). "Glutamate dehydrogenase concentration as a determinant in the effect of purine nucleotides on ... Huang, CY; Frieden, C (1972). "The mechanism of ligand-induced structural changes in glutamate dehydrogenase. Studies of the ... Fisher, Harvey F. (2006). "Glutamate Dehydrogenase-ligand Complexes and Their Relationship to the Mechanism of the Reaction". ... what is now called the morpheein model and showed that it accounted for the regulatory behavior of glutamate dehydrogenase. ...

... the ELFV dehydrogenase family of enzymes include glutamate, leucine, phenylalanine and valine dehydrogenases. These enzymes are ... Glutamate dehydrogenases EC 1.4.1.2, EC 1.4.1.3 and EC 1.4.1.4 (GluDH) are enzymes that catalyse the NAD- and/or NADP-dependent ... Benachenhou-Lahfa N, Forterre P, Labedan B (April 1993). "Evolution of glutamate dehydrogenase genes: evidence for two ... "Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family". ...

Glutamate dehydrogenase catalyzes the reductive amination of α-ketoglutarate to glutamate. A transamination reaction takes ... Proline and arginine are both derived from glutamate. Serine, formed from 3-phosphoglycerate, which comes from glycolysis, is ... Glutamine is synthesized from NH4+ and glutamate, and asparagine is synthesized similarly. ...

... his thesis described studies structural transitions of the enzyme glutamate dehydrogenase using new methods based on ... a fluorescent conformational probe for glutamate dehydrogenase". Biochem. J. 114 (2): 407-417. doi:10.1042/bj1140407. PMC ...

Fahien LA, Kmiotek EH, MacDonald MJ, Fibich B, Mandic M (Aug 1988). "Regulation of malate dehydrogenase activity by glutamate, ... Malate dehydrogenase, mitochondrial also known as malate dehydrogenase 2 is an enzyme that in humans is encoded by the MDH2 ... Thus, glutamate can react with the aminotransferase in this complex without glutamate inhibiting production of oxaloacetate by ... In addition, association of malate dehydrogenase with these other two enzymes enhances malate dehydrogenase activity due to a ...

Another common genetic cause of HI results from changes in the gene for the enzyme glutamate dehydrogenase (GDH). This genetic ... Shortly thereafter, mutations in glucokinase (GCK) and glutamate dehydrogenase (GLUD1) were also identified to cause HI. The ... "Hyperinsulinism and Hyperammonemia in Infants with Regulatory Mutations of the Glutamate Dehydrogenase Gene". New England ... "Hyperinsulinism and Hyperammonemia in Infants with Regulatory Mutations of the Glutamate Dehydrogenase Gene". New England ...

"Antagonistic homotropic interactions as a possible explanation of coenzyme activation of glutamate dehydrogenase". FEBS Letters ... He worked primarily on liver alcohol dehydrogenases, and is well known in enzymology for his idiosyncratic way of representing ...

"Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12". Gene. 27 (2): 193-199. doi: ...

gdhA codes for the glutamate dehydrogenase and links citrate cycle and nitrogen metabolism. A study combining a transcriptome ... Pirin has key roles in the central metabolism by regulating the activity of pyruvate dehydrogenase E1 and therefore select if ...

Fahien LA, Kmiotek EH, MacDonald MJ, Fibich B, Mandic M (Aug 1988). "Regulation of malate dehydrogenase activity by glutamate, ... "Regulation of aminotransferase-glutamate dehydrogenase interactions by carbamyl phosphate synthase-I, Mg2+ plus leucine versus ... which is then converted back to oxaloacetate and glutamate, respectively. Another function of GOT2 is that it is believed to ... "Assignment to chromosome 16 of a gene necessary for the expression of human mitochondrial glutamate oxaloacetate transaminase ( ...