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*  Chondroitin sulfate
D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). Some GlcA residues are epimerized into L-iduronic acid (IdoA); ... N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. A chondroitin ... "On Chondroitin Sulphuric Acid". J. Biol. Chem. 15: 69-79. Free PDF online Chondroitin sulfates at the US National Library of ... the stimulation of the synthesis of proteoglycans and hyaluronic acid, and the decrease in catabolic activity of chondrocytes ...
*  Glucuronosyltransferase
... that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a ... The reaction catalyzed by the UGT enzyme involves the addition of a glucuronic acid moiety to xenobiotics and is the most ... The glucuronidation reaction consists of the transfer of the glucuronosyl group from uridine 5'-diphospho-glucuronic acid ( ...
*  Glycosaminoglycan
... β-D-glucuronic acid GlcUA(2S) = 2-O-sulfo-β-D-glucuronic acid IdoUA = α-L-iduronic acid IdoUA(2S) = 2-O-sulfo-α-L-iduronic acid ... glucuronic acid or iduronic acid) or galactose. Glycosaminoglycans are highly polar and attract water. They are therefore ... glucuronic acid, iduronic acid, galactose, galactosamine, glucosamine). They also vary in the geometry of the glycosidic ... Hyaluronic acid Hyaluronic acid is a major component of synovial tissues and fluid, as well as other soft tissues, and endows ...
*  Glucuronidation
UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) is an intermediate in the process and ... Glucuronidation consists of transfer of the glucuronic acid component of uridine diphosphate glucuronic acid to a substrate by ... Pharmacologists have linked drugs to glucuronic acid to allow for more effective delivery of a broad range of potential ... The conjugation of xenobiotic molecules with hydrophilic molecular species such as glucuronic acid is known as phase II ...
*  Glucuronic acid
... and gluconic acid are fermentation products in Kombucha tea. Glucuronic acid is a precursor of ascorbic acid ( ... Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living ... Glucuronic acid (from Ancient Greek γλυκύς "sweet" + οὖρον "urine") is a uronic acid that was first isolated from urine (hence ... Glucuronic acid, like its precursor glucose, can exist as a linear (carboxo-)aldohexose (. 60,000 are too large for renal ...
*  Uridine diphosphate glucuronic acid
UDP glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic ... Glucuronic acid UDP Bontemps Y, Vuillermoz B, Antonicelli F, Perreau C, Danan JL, Maquart FX, Wegrowski Y (Jun 2003). "Specific ... acid (except in primates and guinea pigs). It is made from UDP-glucose by UDP-glucose 6-dehydrogenase (EC 1.1.1.22) using NAD+ ...
*  UDP-glucuronic acid dehydrogenase
... (UDP-4-keto-hexauronic acid decarboxylating) at the US National Library of Medicine Medical ... UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) (EC 1.1.1.305, UDP-GlcUA decarboxylase, ArnADH) ...
*  GLCE
"Entrez Gene: GLCE glucuronic acid epimerase". Grigorieva E, Eshchenko T, Rykova VI, et al. (2008). "Decreased expression of ... and enzyme activity of the full-length heparin/heparan sulfate-glucuronic acid C5-epimerase". J. Biol. Chem. 276 (24): 21538-43 ...
*  N-Acetylglucosamine
Polymerized with glucuronic acid, it forms hyaluronan. GlcNAc has been reported to be an inhibitor of elastase release from ... It is an amide between glucosamine and acetic acid. It has a molecular formula of C8H15NO6, a molar mass of 221.21 g/mol, and ... which is built from alternating units of GlcNAc and N-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the ... lactic acid residue of MurNAc. This layered structure is called peptidoglycan (formerly called murein). GlcNAc is the monomeric ...
*  Lamotrigine
... is metabolized predominantly by glucuronic acid conjugation. Its major metabolite is an inactive 2-n-glucuronide ... Early studies of lamotrigine's mechanism of action examined its effects on the release of endogenous amino acids from rat ... At high concentrations, it had no effect on spontaneous or potassium evoked amino acid release. These studies suggested that ... It appears to increase the action of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central ...
*  UDP-glucuronate 5'-epimerase
Jacobson B; Davidson EA (1962). "Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5- ... Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl ...
*  Estriol glucuronide
... as well as estriol 16α-β-D-glucosiduronic acid, is a natural, steroidal estrogen and the glucuronic acid (β-D-glucopyranuronic ... Geoffrey Dutton (2 December 2012). Glucuronic Acid Free and Combined: Chemistry, Biochemistry, Pharmacology, and Medicine. ... "Isolation and characterization of estriol 16 alpha-glucosiduronic acid from human pregnancy urine". J. Biol. Chem. 238: 1273-82 ... acid) conjugate of estriol. It occurs in high concentrations in the urine of pregnant women as a reversibly formed metabolite ...
*  Glucuronate isomerase
KILGORE WW, STARR MP (1959). "Catabolism of galacturonic and glucuronic acids by Erwinia carotovora". J. Biol. Chem. 234: 2227- ... Ashwell G, Wahba AJ, Hickman J (1960). "Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid ... Other names in common use include uronic isomerase, uronate isomerase, D-glucuronate isomerase, uronic acid isomerase, and D- ...
*  Fructuronate reductase
Kilgore WW, Starr MP (1959). "Catabolism of galacturonic and glucuronic acids by Erwinia carotovora". J. Biol. Chem. 234: 2227- ... Hickman J; Ashwell G (1960). "Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D- ... mannonic acid dehyrogenases in Escherichia coli". J. Biol. Chem. 235: 1566-1570. ...
*  Glucuronate-2-sulfatase
Shaklee PN, Glaser JH, Conrad HE (1985). "A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans". J ...
*  Glycosynthase
Substrates of glycosynthase include Glucose, Galactose, Mannose, Xylose, and Glucuronic acid. Modern methods to prepare ... The leaving group is displaced by an alcohol of the acceptor sugar aided by the active site general base amino acid of the ... The first was that a change of the active site nucleophile of a glycosidase from a carboxylate to another amino acid resulted ... Mutation of the active site nucleophile to a non-nucleophilic amino acid prevents the formation of a covalent intermediate. An ...
*  Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
UDP-glucuronic acid:anthocyanin glucuronosyltransferase, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta- ... "UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics ... Osmani, S.A.; Bak, S.; Imberty, A.; Olsen, C.E.; Møller, B.L. (2008). "Catalytic key amino acids and UDP-sugar donor ...
*  Inositol oxygenase
Release of D-glucuronic acid is achieved in the fourth step. Myo-inositol can be ingested from fruits and vegetables and ... Inositol Glucuronic acid Oxygenases Bollinger JM, Diao Y, Matthews ML, Xing G, Krebs C (February 2009). "myo-Inositol oxygenase ... In the kidney, MIOX converts myo-inositol to glucuronic acid which is then able to enter the glucuronate-xylulose pathway for ... V. Purification and properties of the enzyme that cleaves inositol to D-glucuronic acid". The Journal of Biological Chemistry. ...
*  TMEM241
"UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [Homo sapien - Protein - NCBI]". www.ncbi.nlm.nih.gov. Retrieved 2016 ... and is particularly rich in the amino acid phenylalanine, containing twice the normal proportion of this amino acid. TMEM241 is ...
*  Crigler-Najjar syndrome
UGT1A1 normally catalyzes the conjugation of bilirubin and glucuronic acid within hepatocytes. Conjugated bilirubin is more ...
*  Dydrogesterone
DHD is preponderantly present in the urine as a conjugate of glucuronic acid. Approximately 85% of the oral dose is ...
*  David Sidney Feingold
Enzymatic synthesis of uridine diphosate glucuronic acid and uridine diphosphate galacturonic acid with extracts from Phaseolus ... Enzymatic synthesis of uridine diphosate glucuronic acid and uridine diphosphate galacturonic acid with extracts from Phaseolus ... Decarboxylation of uridine diphosphate-D-glucuronic acid by an enzyme preparation from hen oviduct. Bdolah, A. and Feingold, D ... The 4-epimerization and decarboxylation of DUP-D-glucuronic acid by extracts of Phaseolus aureus seedings. Decarboxylation of ...
*  Pethidine
... 's metabolites are further conjugated with glucuronic acid and excreted into the urine. In data from the U.S. Drug ... Pethidine is quickly hydrolysed in the liver to pethidinic acid and is also demethylated to norpethidine, which has half the ...
*  Soyasapogenol glucuronosyltransferase
Kurosawa, Y.; Takahara, H.; Shiraiwa, M. (2002). "UDP-glucuronic acid:soyasapogenol glucuronosyltransferase involved in saponin ...
*  Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
Breazeale, S.D.; Ribeiro, A.A.; Raetz, C.R. (2002). "Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin- ...
*  Sumatriptan
... acetic acid which is then conjugated to glucuronic acid. These metabolites are excreted in the urine and bile. Only about 3% of ...
*  Glucuronokinase
Neufeld EF, Feingold DS, Hassid WZ (1959). "Enzymic phosphorylation of D-glucuronic acid by extracts from seedlings of ...