PMID 18281618 Wang D, Pascual JM, De Vivo D. Glucose Transporter Type 1 Deficiency Syndrome. In: Adam MP, Ardinger HH, Pagon RA ... deficiency and glucose transporter 1 deficiency syndrome, which prevent the body from using carbohydrates as fuel, leading to a ... However, the types of carbohydrates consumed are restricted to those that have a glycaemic index lower than 50. Like the ... This could pose a problem for the brain, since it is normally fuelled solely by glucose, and most fatty acids do not cross the ...

There are two types of secondary active transporter found within the kidney tubule; close to the glomerulus, where glucose ... There are over 10 different types of glucose transporters; however, the most significant for study are GLUT1-4. GLUT1 and GLUT3 ... rate of glucose entry is proportional to blood glucose levels. GLUT4 transporters are insulin sensitive, and are found in ... glucose reenters the bloodstream through facilitated diffusion through GLUT2 transporters. Hence reabsorption of glucose is ...

These include a fungal phosphate transporter PiPT, plant nitrate transporter NRT1.1, and the human glucose transporter GLUT1. ... Atypical MFS Transporter Families), suggesting there are at least 64 different families including SLC proteins of MFS type. Pao ... Deng D, Xu C, Sun P, Wu J, Yan C, Hu M, Yan N (June 2014). "Crystal structure of the human glucose transporter GLUT1". Nature. ... Pascual JM, Wang D, Lecumberri B, Yang H, Mao X, Yang R, De Vivo DC (May 2004). "GLUT1 deficiency and other glucose transporter ...

... the protein that transports glucose across the blood brain barrier. Glucose Transporter Type 1 Deficiency Syndrome has an ... "Glucose Transporter Type 1 Deficiency Syndrome". GeneReviews.{{cite journal}}: CS1 maint: multiple names: authors list (link) ... "Glucose transporter type 1 deficiency syndrome , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". ... GLUT1 deficiency syndrome, also known as GLUT1-DS, De Vivo disease or Glucose transporter type 1 deficiency syndrome, is an ...

HTLV-II entry in target cells is mediated by the glucose transporter GLUT1. HTLV-1 and HTLV-2 share broad similarities in their ... "HTLV Type I and Type II". NORD (National Organization for Rare Disorders). Retrieved 2019-02-22. "Human T-cell leukemia virus ... Manel N, Kim FJ, Kinet S, Taylor N, Sitbon M, Battini JL (November 2003). "The ubiquitous glucose transporter GLUT-1 is a ... Human T- leukemia, type 2 (HTLV-2) generally causes no signs or symptoms. Although HTLV-2 has not been definitively linked with ...

2001). "Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome ... 2003). "Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary ... SLC2A10 is a member of the facilitative glucose transporter family, which plays a significant role in maintaining glucose ... Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene. ...

... glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia". Experimental Cell ... GLUT1 is the most abundantly expressed of the family thought to maintain basal glucose transport in almost all cell types. ... April 2001). "Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in ... Flier JS, Mueckler MM, Usher P, Lodish HF (March 1987). "Elevated levels of glucose transport and transporter messenger RNA are ...

Sep 2009). "Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type ... 2007). "The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes". Proc. Natl. Acad. Sci. U ... Zinc transporter 8 (ZNT8) is a protein that in humans is encoded by the SLC30A8 gene. ZNT8 is a zinc transporter related to ... Feb 2010). "New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk". Nature ...

Bouché C, Serdy S, Kahn CR, Goldfine AB (October 2004). "The cellular fate of glucose and its relevance in type 2 diabetes". ... Metal micronutrients are taken up into organisms by specific transporters and bind to storage proteins such as ferritin or ... where it can be used for the production of glucose. Other than fat, glucose is stored in most tissues, as an energy resource ... Three types of photosynthesis occur in plants, C3 carbon fixation, C4 carbon fixation and CAM photosynthesis. These differ by ...

Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) also known as glucose transporter type 10/11 (GLUT ... "Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various ... "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 11". Sasaki T, Minoshima S, Shiohama A, Shintani ... "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of ...

Manel N, Kim FJ, Kinet S, Taylor N, Sitbon M, Battini JL (November 2003). "The ubiquitous glucose transporter GLUT-1 is a ... The most widespread genotype is type A. Types B, D, E, F and G have only been isolated from Central Africa. Type C is only ... Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus (HTLV-I), also called the adult T-cell lymphoma virus type ... a glucose transporter, on target cells. HTLV-1 is also associated with adult T-cell leukemia/lymphoma and has been quite well ...

"Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma". Histology and ... Sui D, Wilson JE (October 2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type ... By phosphorylating glucose, HK3 effectively prevents glucose from leaving the cell and, thus, commits glucose to energy ... Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. ...

... errors of metabolism Congenital disorder of glycosylation Mitochondrial disorders Peroxisomal disorder Glucose transporter ... Microcephaly is a type of cephalic disorder. It has been classified in two types based on the onset: Isolated Familial ( ... 18 (5): 591-6. doi:10.1016/j.stem.2016.03.012. PMC 4860115. PMID 27038591. Li, C; Xu, D; Ye, Q; Hong, S; Jiang, Y; Liu, X; ... 88 (5): 536-47. doi:10.1016/j.ajhg.2011.04.003. PMC 3146728. PMID 21529751. Johnson, Matthew B.; Sun, Xingshen; Kodani, Andrew ...

GLUT-1 acts as a facilitative transporter of glucose, transporter glucose along its concentration gradient. When glucose binds ... certain tissue types express this transporter more so than others. GLUT-1 is expressed in high levels on erythrocytes, ... Both transporters are MFS transporters and possess 29% sequence identity (4). GLUT-1 is a glucose transporter present in most ... Olson, A.L., and Pessin, J.E. (1996). Structure, function, and regulation of the mammalian facilitative glucose transporter ...

Milder DA, Milder TY, Kam PC (August 2018). "Sodium-glucose co-transporter type-2 inhibitors: pharmacology and peri-operative ... DKA happens most often in those with type 1 diabetes but can also occur in those with other types of diabetes under certain ... Each year, about 4% of type 1 diabetics in the United Kingdom develop DKA, versus 25% of type 1 diabetics in Malaysia. DKA was ... "Type 1 diabetes in adults: diagnosis and management". National Institute for Health and Care Excellence. August 2015. Archived ...

Efficacy and Safety of Sodium-Glucose Co-Transporter Type 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes Mellitus". ... Milder DA, Milder TY, Kam PC (August 2018). "Sodium-glucose co-transporter type-2 inhibitors: pharmacology and peri-operative ... Glucose is later reabsorbed by passive transfer of endothelial cells into the interstitial glucose transporter protein. Ratios ... Scheen AJ (2014). "Drug-Drug Interactions with Sodium-Glucose Cotransporters Type 2 (SGLT2) Inhibitors, New Oral Glucose- ...

Sotaglifozin is a sodium-glucose co-transporter 1 and 2 inhibitor that reduces both postprandial glucose and insulin levels by ... The US Food and Drug Administration (FDA) refused its approval for use in combination with insulin for the treatment of type 1 ... a dual sodium-dependent glucose transporter 1/2 inhibitor". Diabetes & Vascular Disease Research. 12 (2): 101-10. doi:10.1177/ ... Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption. The Journal ...

... glucose transporter type 1 deficiency, episodic ataxia type 2, gluten ataxia, glutamic acid decarboxylase ataxia. Novel ... Spinal disorders of various types may cause sensory ataxia from the lesioned level below, when they involve the dorsal columns ... Cerebellar ataxia can have many causes despite normal neuroimaging.[citation needed] Any type of focal lesion of the central ... This results in a characteristic type of irregular, uncoordinated movement that can manifest itself in many possible ways, such ...

AI-2 is actively transported by the Lsr ABC-type transporter into the cell in Enterobacteriaceae and few other bacterial taxa ... AI-2 signalling is also regulated by glucose and cAMP/CRP via the lsr operon. In the presence of glucose, low levels of cAMP/ ... Without glucose, cAMP-CRP is needed to stimulate the lsr expression, while LsrR represses its expression in the absence of the ... "Detection of AI-2 receptors in genomes of Enterobacteriaceae suggests a role of type-2 quorum sensing in closed ecosystems". ...

Glucose+Transporter+Type+3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ... Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a ... GLUT3 is considered the main but not the exclusive neuronal glucose transporter, whereas other glucose transporters have also ... 1998). "Glucose transporter expression in brain: relationship to cerebral glucose utilization". Dev. Neurosci. 20 (4-5): 369-79 ...

MsiK, the protein encoded by msiK genes, is the ATPase subunit within certain ABC-type membrane transporter proteins. MsiK is ... it was suggested that msiK RNAs are probably not involved in sensing glucose themselves, but are more likely a part of a ... 186 (5): 1362-1373. doi:10.1128/jb.186.5.1362-1373.2004. PMC 344420. PMID 14973030. Page for msiK RNA at Rfam (Orphaned ... The RNA is always found in the presumed 5' untranslated regions of genes annotated as msiK, and is therefore hypothesized to be ...

Bunn RC, Jensen MA, Reed BC (1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a ... It is associated with Charcot-Marie-Tooth disease, type 2A1. KIF1B has been shown to interact with GIPC1. GRCh38: Ensembl ... "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the ... 1998). "Linkage mapping of the gene for Charcot-Marie-Tooth disease type 2 to chromosome 1p (CMT2A) and the clinical features ...

In addition, reduced glucose uptake by mutated transporters compared with wild-type in Xenopus oocytes confirmed a pathogenic ... encoding the glucose transporter GLUT1". Brain. 131 (Pt 7): 1831-44. doi:10.1093/brain/awn113. PMC 2442425. PMID 18577546. ... to help restore the unbalance created by the decreased amount of glucose in the brain caused by the faulty GLUT1 transporter. ... All mutations that were observed appeared to only affect the ability of GLUT1 to transport glucose and not the ability for it ...

... but by glucose transporters that were inadequately mobilized in Type 2 patients, and has subsequently been developed by Doug ... was used to measure glucose pathways in Type 2 Diabetics as compared to controls. This showed that the flux of glycogen ... Yeast studies were conducted during the 1980s and their results were the basis of a Metabolic Control Analysis of glucose ... synthesis, which stored glucose as muscle glycogen, was controlled, not by Glycogen Synthase, as had been assumed, ...

Bunn RC, Jensen MA, Reed BC (1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a ... T14853, TIP/GIPC binds to a type I recognition sequence in alpha 6A/alpha 5 and a novel sequence in alpha 6B". J. Biol. Chem. ... Bunn RC, Jensen MA, Reed BC (April 1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that ... T14853, TIP/GIPC binds to a type I recognition sequence in alpha 6A/alpha 5 and a novel sequence in alpha 6B". J. Biol. Chem. ...

Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found ... SGLT2 inhibitors, also called gliflozins, are used in the treatment of type 2 diabetes. SGLT2 is only found in kidney tubules ... These co-transporters are an example of secondary active transport. Members of the GLUT family of glucose uniporters then ... Of these, SLC5A4/SGLT3 (SAAT1) is a low-affinity transporter for glucose, but seems to have more of an electric function. The ...

SGLT-2 is a member of the glucose transporter family and is a low-affinity, high-capacity glucose transporter. SGLT-2 is mainly ... Gliflozins are a class of drugs in the treatment of type 2 diabetes (T2D). They act by inhibiting sodium/glucose cotransporter ... which are secondary active glucose transporters. The sodium glucose transporters proteins SGLT-1 and SGLT-2 are the two premier ... Almost all remaining filtered glucose is reabsorbed by sodium/glucose transporter 1 so under normal circumstances almost all ...

Other types of interaction: Drugs which induce certain enzymes in the liver, e.g., barbiturates, phenytoin, carbamazepine and ... Maprotiline Ameliorates High Glucose-Induced Dysfunction in Renal Glomerular Endothelial Cells. Experimental and Clinical ... "Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters ... The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma. Int J ...

Bays, Harold (2013). "Sodium glucose co-transporter type 2 (SGLT2) inhibitors: Targeting the kidney to improve glycemic control ... Idris, Iskandar; Donnelly, Richard (2009). "Sodium-glucose co-transporter-2 inhibitors: An emerging new class of oral ... lowering the amount of glucose in the blood. Phlorizin was studied as a potential pharmaceutical treatment for type 2 diabetes ... Phlorizin is an inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this action reduces ...

PKB triggers the translocation of glucose transporter (GLUT4) containing vesicles to the cell membrane, via the activation of ... The Insulin Receptor is a type of tyrosine kinase receptor, in which the binding of an agonistic ligand triggers ... Both diseases present with fluctuations of the glucose level: After a meal the glucose is initially very high, and then falls ... translocation of Glut-4 transporter to the plasma membrane and influx of glucose (3), glycogen synthesis (4), glycolysis (5), ...