Glucose 6-phosphate
Glucose Glucose 1-phosphate Glucose-6-phosphate dehydrogenase deficiency Glycogen Pentose phosphate pathway Litwack, Gerald ( ... After being converted to G6P, the molecule can be turned into glucose 1-phosphate by phosphoglucomutase. Glucose 1-phosphate ... The cleaved molecule is in the form of glucose 1-phosphate, which can be converted into G6P by phosphoglucomutase. Next, the ... The catalytic site is found on the lumenal face of the membrane, and removes the phosphate group from glucose 6-phosphate ...
Glucose-6-phosphate dehydrogenase
Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6- ... "Entrez Gene: G6PD glucose-6-phosphate dehydrogenase". Tian WN, Braunstein LD, Pang J, Stuhlmeier KM, Xi QC, Tian X, Stanton RC ... Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction D- ... Glucose-6-phosphate dehydrogenase is also an enzyme in the Entner-Doudoroff pathway, a type of glycolysis. Clinically, an X- ...
Glucose-6-phosphate isomerase
Fructose-1-phosphate-aldolase enzyme, which converts fructose to glucose GPI is known to interact with: AMFR, and HER2. Click ... This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a ... Walker JI, Faik P, Morgan MJ (August 1990). "Characterization of the 5' end of the gene for human glucose phosphate isomerase ( ... Xu W, Lee P, Beutler E (October 1995). "Human glucose phosphate isomerase: exon mapping and gene structure". Genomics. 29 (3): ...
Glucose-6-phosphate 1-epimerase
In enzymology, a glucose-6-phosphate 1-epimerase (EC 5.1.3.15) is an enzyme that catalyzes the chemical reaction alpha-D- ... Wurster B, Hess B (1972). "Glucose-6-phosphate-1-epimerase from baker's yeast. A new enzyme". FEBS Lett. 23 (3): 341-344. doi: ... The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / ... beta-D-glucose 6-phosphate Hence, this enzyme has one substrate, alpha-D-glucose 6-phosphate, and one product, beta-D-glucose 6 ...
Glucose-6-phosphate exchanger SLC37A2
Bartoloni L, Antonarakis SE (February 2004). "The human sugar-phosphate/phosphate exchanger family SLC37". Pflügers Archiv. 447 ... "SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters". PLOS ONE. 6 (9): e23157. Bibcode:2011PLoSO... ... Glucose-6-phosphate exchanger SLC37A2 is a protein that in humans is encoded by the SLC37A2 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: Solute carrier family 37 (glucose-6-phosphate transporter), member 2". Pan CJ, Chen SY, Jun HS, Lin SR, Mansfield ...
Glucose-6-phosphate exchanger SLC37A4
After hydrolysis, glucose and inorganic phosphate are transported back into the cytosol by G6PT2 and G6PT3, respectively. While ... October 1998). "Plasma glucose levels are reduced in rats and mice treated with an inhibitor of glucose-6-phosphate translocase ... resulting in the release of free glucose into the bloodstream. Glucose-6-phosphate translocase is a transmembrane protein ... Glucose-6-phosphate exchanger SLC37A4, also known as glucose-6-phosphate translocase, is an enzyme that in humans is encoded by ...
Glucose-6-phosphate exchanger SLC37A1
Bartoloni L, Antonarakis SE (February 2004). "The human sugar-phosphate/phosphate exchanger family SLC37". Pflügers Archiv. 447 ... inorganic phosphate antiporter, transporting glucose 6-phosphate from the cytoplasm into the lumen of the ER, while ... "SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters". PLOS ONE. 6 (9): e23157. Bibcode:2011PLoSO... ... Glucose-6-phosphate exchanger SLC37A1 is a protein that in humans is encoded by the SLC37A1 gene. SLC37A1 locates to the ...
Glucose-6-phosphate dehydrogenase deficiency
... is an enzyme in the pentose phosphate pathway (see image, also known as the HMP shunt pathway). G6PD converts glucose-6- ... Glucose-6-phosphate dehydrogenase is an enzyme which protects red blood cells, which carry oxygen from the lungs to tissues ... Glucose-6-phosphate dehydrogenase deficiency (G6PDD), which is the most common enzyme deficiency worldwide, is an inborn error ... glucose-6-phosphate dehydrogenase deficiency citing: Gale Encyclopedia of Medicine. Copyright 2008 Pes, G. M., Parodi, G., & ...
Glucose-6-phosphate dehydrogenase (coenzyme-F420)
Glucose-6-phosphate+dehydrogenase+(coenzyme-F420) at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ... Glucose-6-phosphate dehydrogenase (coenzyme-F420) (EC 1.1.98.2, coenzyme F420-dependent glucose-6-phosphate dehydrogenase, F420 ... Purwantini E, Daniels L (May 1996). "Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from ... Purwantini E, Gillis TP, Daniels L (January 1997). "Presence of F420-dependent glucose-6-phosphate dehydrogenase in ...
Glycerol-3-phosphate-glucose phosphotransferase
The systematic name of this enzyme class is sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase. Kiaira JK, Njogu RM (1989 ... In enzymology, a glycerol-3-phosphate-glucose phosphotransferase (EC 2.7.1.142) is an enzyme that catalyzes the chemical ... reaction sn-glycerol 3-phosphate + D-glucose ⇌ {\displaystyle \rightleftharpoons } glycerol + D-glucose 6-phosphate Thus, the ... two substrates of this enzyme are sn-glycerol 3-phosphate and D-glucose, whereas its two products are glycerol and D-glucose 6- ...
Glucose-1-phosphate phosphodismutase
The systematic name of this enzyme class is D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase. This enzyme ... D-glucose 1-phosphate, and two products, D-glucose and D-glucose 1,6-bisphosphate. This enzyme belongs to the family of ... a glucose-1-phosphate phosphodismutase (EC 2.7.1.41) is an enzyme that catalyzes the chemical reaction 2 D-glucose 1-phosphate ... Sidbury JB, Rosenberg LL, Najjar VA (1956). "Muscle glucose-1-phosphate transphosphorylase". J. Biol. Chem. 222 (1): 89-96. ...
Glucose 1-phosphate
... (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon. It can exist in ... free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can ... One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar ... β-Glucose 1-phosphate is found in some microbes. It is produced by inverting α-glucan phosphorylases including maltose ...
Human genetic resistance to malaria
... metabolizing glucose through the pentose phosphate pathway, an anabolic alternative to catabolic oxidation (glycolysis), while ... "Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency". The Lecturio Medical Concept Library. 3 September 2020. Retrieved 23 July ... Some of these disorders are known by fanciful and cryptic names like sickle-cell anemia, thalassaemia, glucose-6-phosphate ... The first line of defense against malaria is mainly exerted by abnormal hemoglobins and glucose-6-phosphate dehydrogenase ...
Glutathione reductase
... of the glucose consumption may be directed to the pentose phosphate pathway (PPP) for production of the NADPH needed for this ... an enzyme in their pentose phosphate pathway that reduces NADP+ to NADPH while catalyzing the conversion of glucose-6-phosphate ... Glucose-6-phosphate dehydrogenase deficient individuals have less NADPH available for the reduction of oxidized glutathione via ... Thus their basal ratio of oxidized to reduced glutathione is significantly higher than that of patients who express glucose-6- ...
Mir-143
Glucose-6-phosphate catalyzing enzyme. Raldh2/aldh1a2 - Represses transcription. Involved in heart tube organization. rxrab - ... 64 (6): 399-408. doi:10.1016/j.biopha.2010.01.018. PMID 20363096. Akao Y, Nakagawa Y, Hirata I, Iio A, Itoh T, Kojima K, ... 17 (6): 398-408. doi:10.1038/cgt.2009.88. PMID 20094072. Clapé C, Fritz V, Henriquet C, Apparailly F, Fernandez PL, Iborra F, ... 6 (10): 1873-82. doi:10.1039/c004401f. PMC 3812686. PMID 20544124. Iio A, Nakagawa Y, Hirata I, Naoe T, Akao Y (2010). " ...
Pea
Favism, or Fava-bean-ism, is a genetic deficiency of the enzyme glucose-6-phosphate dehydrogenase that affects Jews, other ... "Glucose-6-Phosphate Dehydrogenase Deficiency". TheFreeDictionary.com. "Favism - genetic disorder". Encyclopædia Britannica. " ... 93-138, doi:10.1002/9780470650196.ch3, ISBN 978-0-470-65019-6 "sugar pea". TheFreeDictionary.com. Retrieved 15 February 2020. ... 3 ft 3 in to 6 ft 7 in) high. A traditional approach to supporting climbing peas is to thrust branches pruned from trees or ...
6-phosphogluconolactonase
... in which glucose is converted into ribulose 5-phosphate. The oxidative phase of the pentose phosphate pathway releases CO2 and ... The enzyme that precedes 6PGL in the pentose phosphate pathway, glucose-6-phosphate dehydrogenase, exclusively forms the δ- ... "Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin ... The final product, ribulose 5-phosphate, is further processed by the organism during the non-oxidative phase of the pentose ...
Chronic granulomatous disease
"Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency". The Lecturio Medical Concept Library. 3 September 2020. Retrieved 23 July ... "Genotype-dependent variability in flow cytometric evaluation of reduced nicotinamide adenine dinucleotide phosphate oxidase ... This has been reported in women who are homozygous for the genetic defect causing glucose-6-phosphate dehydrogenase deficiency ... 53 (5): 890-6. doi:10.1373/clinchem.2006.083444. PMID 17384005. Roos D, de Boer M (February 2014). "Molecular diagnosis of ...
Vicine
Upon hydrolysis, the glucose part of the molecule is split off and that results in the reduced divicine. Divicine is then taken ... The β-glycosidic bond between glucose and the hydroxyl group at C5 on the pyrimidine ring are hydrolysed to yield the aglycone ... In individuals with a deficiency for glucose 6-phosphate dehydrogenase (G6PD) however, this results in haemolytic anaemia. A 10 ... Luzzatto L, Arese P (January 2018). "Favism and Glucose-6-Phosphate Dehydrogenase Deficiency". The New England Journal of ...
Divicine
Baker, M.; Bosia, A. (1984). "Mechanism of Action of Divicine in a Cell-free System and in Glucose-6-phosphate Dehydrogenase- ... Luzzatto, Lucio; Arese, Paolo (2018-01-04). Longo, Dan L. (ed.). "Favism and Glucose-6-Phosphate Dehydrogenase Deficiency". New ... a disorder that involves a hemolytic response to the consumption of broad beans due to glucose-6-phosphate dehydrogenase (G6PD ... Divicine (2,6-diamino-4,5-dihydroxypyrimidine) is an oxidant and a base with alkaloidal properties found in fava beans and ...
Bernard Horecker
However, he is best known for his work in elucidating the pentose phosphate pathway. Much of his work, especially of the ... Later he worked with Arthur Kornberg on spectroscopic aspects of pyridine nucleotides, with whom he also studied glucose 6- ... Bernard Leonard (Bernie) Horecker (1914-2010) was an American biochemist known for work on the pentose phosphate pathway, and ... Horecker, Bernard L. (2002). "The pentose phosphate pathway". J. Biol. Chem. 277 (50): 47965-47971. doi:10.1074/jbc.X200007200 ...
Fluasterone
However, similarly to DHEA but more strongly, fluasterone is a potent uncompetitive inhibitor of G6PDHTooltip glucose-6- ... phosphate dehydrogenase (Ki = 0.5 μM versus 17 μM for DHEA). The drug retains the antiinflammatory, antihyperplastic, ... 603-. ISBN 978-0-08-055811-0. Schwartz AG, Pashko LL (2004). "Dehydroepiandrosterone, glucose-6-phosphate dehydrogenase, and ... 170-. ISBN 978-3-527-63397-5. Alain Tressaud; Günter Haufe (6 June 2008). Fluorine and Health: Molecular Imaging, Biomedical ...
Prasterone
Hecker PA, Leopold JA, Gupte SA, Recchia FA, Stanley WC (February 2013). "Impact of glucose-6-phosphate dehydrogenase ... Schwartz AG, Pashko LL (April 2004). "Dehydroepiandrosterone, glucose-6-phosphate dehydrogenase, and longevity". Ageing ... 59 (6): 997-1002. doi:10.1111/j.1532-5415.2011.03410.x. PMID 21649617. S2CID 7137809. Wallace MB, Lim J, Cutler A, Bucci L ( ... 85 (6): 718-726. doi:10.1016/j.bcp.2012.12.004. PMID 23270992. Labrie F, Labrie C (April 2013). "DHEA and intracrinology at ...
Methylene blue
Association with glucose-6-phosphate dehydrogenase deficiency". Annals of Internal Medicine. 75 (1): 83-86. doi:10.7326/0003- ... Some examples of anionic surfactants are carboxylates, phosphates, sulfates, and sulfonates.[citation needed] The methylene ... Typically, a solution is made of glucose (dextrose), methylene blue, and sodium hydroxide. Upon shaking the bottle, oxygen ... An Investigation of the methylene blue-catalyzed air oxidation of glucose". Journal of Chemical Education. 89 (11): 1425-1431. ...
Phosphoglucomutase (glucose-cofactor)
This enzyme has at least one effector, D-Glucose. FUJIMOTO A, INGRAM P, SMITH RA (1965). "D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6- ... glucose-cofactor). Other names in common use include glucose phosphomutase, and glucose-1-phosphate phosphotransferase. ... alpha-D-glucose 1-phosphate, and one product, D-glucose 6-phosphate. This enzyme belongs to the family of isomerases, ... is an enzyme that catalyzes the chemical reaction alpha-D-glucose 1-phosphate ⇌ D-glucose 6-phosphate Hence, this enzyme has ...
Sex-chromosome dosage compensation
Similar to mammals, chickens seem to use CpG islands (segments of Cytosine-phosphate-Guanine that are more readily methylated ... Beutler, Ernest (2008). "Glucose-6-phosphate dehydrogenase deficiency: a historical perspective". Blood. 111 (1): 16-24. doi: ... By analyzing the differential expression of two existing, viable alleles for the X-linked enzyme glucose-6-phosphate ... 136 (6): 759-770. doi:10.1086/285130. S2CID 85355967. Mable B.K. (2004). "'Why polyploidy is rarer in animals than in plants': ...
X-chromosome reactivation
This suggested to Ernest Beutler, studying heterozygous females for glucose-6-phosphate dehydrogenase (G6PD) deficiency, that ... Beutler E (January 2008). "Glucose-6-phosphate dehydrogenase deficiency: a historical perspective". Blood. 111 (1): 16-24. doi: ... 61 (6): 531-538. doi:10.1093/jnen/61.6.531. PMID 12071636. Hysolli E, Jung YW, Tanaka Y, Kim KY, Park IH (January 2012). "The ... 161 (6): 1248-1251. doi:10.1016/j.cell.2015.05.039. PMID 26046435. S2CID 13938537. Okamoto I, Patrat C, Thépot D, Peynot N, ...
X-inactivation
Linder D, Gartler SM (October 1965). "Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of ... This suggested to Ernest Beutler, studying heterozygous females for glucose-6-phosphate dehydrogenase (G6PD) deficiency, that ... Beutler E (January 2008). "Glucose-6-phosphate dehydrogenase deficiency: a historical perspective". Blood. 111 (1): 16-24. doi: ... 58 (6): 1101-8. PMC 1915050. PMID 8651285. Holle JR, Marsh RA, Holdcroft AM, Davies SM, Wang L, Zhang K, Jordan MB (July 2015 ...
Phaedon Fessas
IF=11,8 Neonatal jaundice in glucose-6-phosphate- dehydrogenase-deficient infants. FESSAS P, DOXIADIS SA, VALAES T. Br Med J. ... Thalassaemia, sickling, and glucose-6-phosphate-dexydrogenase deficiency. CHOREMIS C, FESSAS P, KATTAMIS C, STAMATOYANNOPOULOS ... 1962 Jan;7:133-8. IF 2,8 Glucose-6-phosphate dehydrogenase deficiency. A new aetiological factor of severe neonatal jaundice. ' ... 1963 Jun 1;1(7292):1182-3. IF=49 Thalassaemia, Glucose-6-Phosphate Dehydrogenase Deficiency, Sickling, and Malarial endemicity ...
Red blood cell
Furthermore, the pentose phosphate pathway plays an important role in red blood cells; see glucose-6-phosphate dehydrogenase ... Defines the Diego Blood Group; Aquaporin 1 - water transporter, defines the Colton Blood Group; Glut1 - glucose and L- ... phosphate depletion, iron deficiency and Wilson's disease. Eryptosis can be elicited by osmotic shock, oxidative stress, and ... instead they produce the energy carrier ATP by the glycolysis of glucose and lactic acid fermentation on the resulting pyruvate ...