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*  Glucocorticoids in hippocampal development
The adult hippocampus is highly enriched in type I (mineralocorticoid, MR) and type II (glucocorticoid, GR) glucocorticoid ... More research is needed to understand the role of glucocorticoids in the context of human hippocampal development. Purves, Dale ... Seckl, JR; Meaney, MJ (Dec 2004). "Glucocorticoid programming". Annals of the New York Academy of Sciences. 1032: 63-84. doi: ... The following will provide an introduction to hippocampal development with particular focus on the role of glucocorticoid ...
*  Glucocorticoid
... glucocorticoids could induce a potent diuresis. Glucocorticoids bind to the cytosolic glucocorticoid receptor (GR), a type of ... glucocorticoid-induced TNF receptor) Glucocorticoid receptor Immunosuppressive drug Membrane glucocorticoid receptor Metyrapone ... Glucocorticoids may be used in low doses in adrenal insufficiency. In much higher doses, oral or inhaled glucocorticoids are ... Any glucocorticoid can be given in a dose that provides approximately the same glucocorticoid effects as normal cortisol ...
*  Glucocorticoid receptor
Membrane glucocorticoid receptor Familial/sporadic glucocorticoid resistance (Chrousos Syndrome) Selective glucocorticoid ... The GR is abnormal in familial glucocorticoid resistance. In central nervous system structures, the glucocorticoid receptor is ... "Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through ... The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor ...
*  Membrane glucocorticoid receptor
... s (mGRs) are a group of receptors which bind and are activated by glucocorticoids such as ... "Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands". Steroids. ... In accordance, glucocorticoids are known to affect cognition, stress-adaptive behavior, and neuroendocrine output (e.g., ... mGRs have been implicated in the rapid effects of glucocorticoids in the early central stress response via modulating neuronal ...
*  Glucocorticoid deficiency 1
... (FGD or GCCD) is an adrenocortical failure characterized by low levels of plasma cortisol produced ... Clark AJ, McLoughlin L, Grossman A (October 1993). "Familial glucocorticoid deficiency associated with point mutation in the ... Tsigos C, Arai K, Hung W, Chrousos GP (November 1993). "Hereditary isolated glucocorticoid deficiency is associated with ... cause familial glucocorticoid deficiency type 2". Nature Genetics. 37 (2): 166-170. doi:10.1038/ng1501. PMID 15654338. ...
*  Glucocorticoid remediable aldosteronism
... (GRA), also describable as aldosterone synthase hyperactivity, is an autosomal dominant ... McMahon GT, Dluhy RG (October 2004). "Glucocorticoid-remediable aldosteronism". Arq Bras Endocrinol Metabol. 48 (5): 682-6. doi ... However, in subjects with glucocorticoid-remediable aldosteronism, ACTH increases the activity of existing aldosterone synthase ... April 2007). "A German family with glucocorticoid-remediable aldosteronism". Nephrol. Dial. Transplant. 22 (4): 1123-30. doi: ...
*  Selective glucocorticoid receptor modulator
Both non-selective glucocorticoids and selective glucocorticoid receptor agonists work by binding to and activating the ... Just like glucocorticoids, SEGRAMs bind to and activate GR. However, in contrast to glucocorticoids, SEGRAMs selectively ... Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as ... Ayroldi E, Macchiarulo A, Riccardi C (December 2014). "Targeting glucocorticoid side effects: selective glucocorticoid receptor ...
*  Biological aspects of fluorine
Goulding, Nicolas J.; Flower, Rod J. (2001). Glucocorticoids. Springer. p. 40. ISBN 9783764360597. Raj, P. Prithvi; Erdine, ...
*  Steroid dementia syndrome
... induced by glucocorticoids. Dementia-like symptoms have been found in some individuals who have been exposed to glucocorticoid ... Elevated glucocorticoid activity is associated with down-regulation of GRs (known as "glucocorticoid cascade hypothesis"), ... anti-glucocorticoids psychoactive drugs that up-regulate the GRII glucocorticoid receptor:tricyclic antidepressants: ... Glucocorticoid medications have been known to be associated with significant side effects involving behavior and mood, ...
*  Fluocortolone
... is a glucocorticoid used in the treatment of several conditions, including hemorrhoids. It is similar to ...
*  Secondary hypertension
... glucocorticoid remediable aldosteronism Cushing's syndrome - an excessive secretion of glucocorticoids causes the hypertension ... Cushing's syndrome can be caused by taking glucocorticoid drugs, or by tumors that produce cortisol or adrenocorticotropic ... Dodt C, Wellhöner JP, Schütt M, Sayk F (January 2009). "[Glucocorticoids and hypertension]". Der Internist (in German). 50 (1 ... McMahon GT, Dluhy RG (2004). "Glucocorticoid-remediable aldosteronism". Cardiology in Review. 12 (1): 44-48. doi:10.1097/01.crd ...
*  Annexin A1
Peers SH, Smillie F, Elderfield AJ, Flower RJ (January 1993). "Glucocorticoid-and non-glucocorticoid induction of lipocortins ( ... Glucocorticoids stimulate production of lipocortin. In this way, synthesis of eicosanoids are inhibited. Annexin A1 has been of ... Glucocorticoids (such as budesonide, cortisol, and beclomethasone) are a class of endogenous or synthetic anti-inflammatory ... Because they suppress inflammatory pathways, long-term use of glucocorticoid drugs can lead to side-effects such as ...
*  Lichen nitidus
... topical glucocorticoids may be tried. If the disease process is symptomatic, generalized and extensive, oral glucocorticoids ...
*  Effects of stress on memory
Glucocorticoids facilitate and impair the actions of stress in the brain memory process. Cortisol is a known biomarker for ... 2009). "Glucocorticoids and the regulation of memory in health and disease". Front Neuroendocrinol. 30 (3): 358-70. doi:10.1016 ... One class of stress hormone responsible for negatively affecting memory is the glucocorticoids (GCs), the most notable of which ... Moreover, there are new approaches to treat phobias and enhance exposure therapy with glucocorticoids. Social phobics display a ...
*  Amcinonide
Cyclocort is a synthetic corticosteroid created to imitate natural glucocorticoids. In order to do so, amcinonide acts as an ... It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while ... Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with ... Due to Amcinonide's high affinity for the glucocorticoid receptor, a neuroactive ligand-receptor interaction occurs and the ...
*  Poor ovarian reserve
Glucocorticoid therapy. A recent (2007) randomized double blind study done in Egypt reported a statistically significant ...
*  Aspergillus clavatus
In severe cases, glucocorticoids are used. Microgranulomatous hypersensitivity pneumonitis, where interstitial granulomatous ...
*  Adrenal gland
Glucocorticoids Cortisol is the main glucocorticoid in humans. In species that do not create cortisol, this role is played by ... Regulation Glucocorticoids are under the regulatory influence of the hypothalamus-pituitary-adrenal (HPA) axis. Glucocorticoid ... Glucocorticoids have many effects on metabolism. As their name suggests, they increase the circulating level of glucose. This ... Glucocorticoids also have effects unrelated to the regulation of blood sugar levels, including the suppression of the immune ...
*  Immunosuppressive drug
Glucocorticoids also suppress the humoral immunity, causing B cells to express smaller amounts of IL-2 and IL-2 receptors. This ... Glucocorticoids suppress the cell-mediated immunity. They act by inhibiting genes that code for the cytokines Interleukin 1 (IL ... Glucocorticoids also stimulate the lipocortin-1 escaping to the extracellular space, where it binds to the leukocyte membrane ... Glucocorticoids influence all types of inflammatory events, no matter their cause. They induce the lipocortin-1 (annexin-1) ...
*  Cortisol
In fetal lambs, glucocorticoids (principally cortisol) increase after about day 130, with lung surfactant increasing greatly, ... Cortisol is a steroid hormone, in the glucocorticoid class of hormones. When used as a medication, it is known as ... Elenkov IJ (June 2004). "Glucocorticoids and the Th1/Th2 balance". Annals of the New York Academy of Sciences. 1024 (1): 138-46 ... ISBN 0-8138-1106-6. Coderre L, Srivastava AK, Chiasson JL (June 1991). "Role of glucocorticoid in the regulation of glycogen ...
*  Giant-cell arteritis
... this pathway is suppressed with glucocorticoids. Palpation of the head reveals prominent temporal arteries with or without ...
*  Psychoneuroimmunology
Glucocorticoids also inhibit the further secretion of corticotropin-releasing hormone from the hypothalamus and ACTH from the ... Glucocorticoids and catecholamines influence immune cells. Endorphins from pituitary and adrenal medulla act on immune system. ... This foundational work led to a rich line of research on the biological functioning of glucocorticoids. Mid-20th century ... Chronic secretion of stress hormones, glucocorticoids (GCs) and catecholamines (CAs), as a result of disease, may reduce the ...
*  Social grooming
Glucocorticoids are steroid hormones that are synthesized in the adrenal cortex and are a part of the group of corticosteroids ... Glucocorticoids are involved in immune function, and are a part of the feedback system that reduces inflammation. Further, ... Social grooming can change the number of glucocorticoid receptors, which can result in increased immune function. Studies have ... Sapolsky, Robert M.; Romero, L. Michael; Munck, Allan U. (2000-02-01). "How Do Glucocorticoids Influence Stress Responses? ...
*  Prednisone
... glucocorticoid analogue drugs such as prednisone down-regulate the natural synthesis of glucocorticoids. This mechanism leads ... Liu, C; Chen, Y; Kang, Y; Ni, Z; Xiu, H; Guan, J; Liu, K (October 2011). "Glucocorticoids improve renal responsiveness to ... Glucocorticoids act to inhibit feedback of both the hypothalamus, decreasing corticotropin-releasing hormone [CRH], and ... In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial ...
*  Regulatory macrophages
Elenkov, IJ (Jun 2004). "Glucocorticoids and the Th1/Th2 balance". Annals of the New York Academy of Sciences. 1024: 138-46. ... Activation of the hypothalamic-pituitary-adrenal axis leads to production of glucocorticoids that cause decreased production of ...