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*  Reprogramming
Due to the phenomenon of genomic imprinting, maternal and paternal genomes are differentially marked and must be properly ... In vitro manipulation of pre-implantation embryos has been shown to disrupt methylation patterns at imprinted loci and plays a ... Mann MR, Chung YG, Nolen LD, Verona RI, Latham KE, Bartolomei MS (September 2003). "Disruption of imprinted gene methylation ... Mathers JC (June 2006). "Nutritional modulation of ageing: genomic and epigenetic approaches". Mech. Ageing Dev. 127 (6): 584-9 ...
*  Long non-coding RNA
"Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes". Genes & Development. 20 (10): ... In general, imprinted genes are clustered together on chromosomes, suggesting the imprinting mechanism acts upon local ... "Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes". Genes & Development. 15 ... A differentially methylated imprinting centre also overlaps the promoter of a long antisense ncRNA Air that is responsible for ...
*  Genomic imprinting
Forms of genomic imprinting have been demonstrated in fungi, plants and animals. As of 2014, there are about 150 imprinted ... Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting ... Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner. ... Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process ...
*  Hybrid growth disorders
"Genomic Imprinting". learn.genetics.utah.edu. Retrieved 2017-11-10. Haldane, J.B.S. (October 1922). "Sex ratio and unisexual ... A study on hybrid mice which investigated the possible causes for hybrid growth disorders reveals genomic imprinting to have a ... Paternal imprinting may increase growth to maximize maternal resources allocated to his progeny, while maternal imprinting may ... a study of hybrids between dwarf hamster species Phodopus campbelli and Phodopus sungorus suggests that gene imprinting causes ...
*  Heritability of autism
Genomic imprinting models have been proposed; one of their strengths is explaining the high male-to-female ratio in ASD. One ... that alterations of genomic imprinting help to mediate the development of these two sets of conditions, and that ASD involves ... Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism. Pediatr Res. 2000;47(1 ... The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13. Neurobiol Dis. 2008;38(2):181-91. doi:10.1016/j ...
*  Confined placental mosaicism
Kalousek DK, Barrett IJ (1994). "Genomic imprinting related to prenatal diagnosis". Prenatal Diagnosis. 14 (13): 1191-1201. doi ... Certain chromosomes carry imprinted genes involved in growth or placental function, which may contribute to impaired pregnancy ... Ledbetter DH, Engel E (1 September 1995). "Uniparental disomy in humans: development of an imprinting map and its implications ... When CPM is detected on CVS involving certain chromosomes which are known or suspected to carry imprinted genes, molecular ...
*  DNA (cytosine-5)-methyltransferase 3A
Reik W, Walter J (January 2001). "Genomic imprinting: parental influence on the genome". Nature Reviews Genetics. 2 (1): 21-32 ... Genetic imprinting prevents parthenogenesis in mammals, and hence forces sexual reproduction and its multiple consequences on ... DNMT3A is essential for genetic imprinting. In mice, this gene has shown reduced expression in ageing animals causes cognitive ... imprinting and genome stability. DMT3A is a 130 kDa protein encoded by 23 exons found on chromosome 2p23 in humans. There ...
*  Epigenetics of autism
Genomic imprinting may also contribute to ASD. Genomic imprinting is another example of epigenetic regulation of gene ... Results from numerous studies have identified several genomic regions known to be subject to imprinting, candidate genes, and ... The imprinted genes of 15q11-13 are under the control of a common regulatory sequence, the imprinting control region (ICR). The ... However, evidently it does not play a role in the maintenance of imprinting. Imprinting and epigenetics of chromosome 7q in ASD ...
*  DNA methylation
Due to the phenomenon of genomic imprinting, maternal and paternal genomes are differentially marked and must be properly ... Li, En; Beard, Caroline; Jaenisch, Rudolf (1993-12-25). "Role for DNA methylation in genomic imprinting". Nature. 366 (6453): ... DNA methylation appears critical for the maintenance of mono-allelic silencing in the context of genomic imprinting and X ... of which DNA methylation is a significant contributor Epigenome Genome Genomic imprinting, an inherited repression of an allele ...
*  Polyadenylation
"Regulation of alternative polyadenylation by genomic imprinting". Genes & Development. 22 (9): 1141-6. doi:10.1101/gad.473408. ... Saini, H. K.; Griffiths-Jones, S.; Enright, A. J. (2007). "Genomic analysis of human microRNA transcripts". Proceedings of the ...
*  Epigenetics
This is due to the presence of genomic imprinting in the region. Beckwith-Wiedemann syndrome is also associated with genomic ... Some human disorders are associated with genomic imprinting, a phenomenon in mammals where the father and mother contribute ... Li E, Beard C, Jaenisch R (November 1993). "Role for DNA methylation in genomic imprinting". Nature. 366 (6453): 362-5. Bibcode ... Online Mendelian Inheritance in Man (OMIM) 105830 Wood AJ, Oakey RJ (November 2006). "Genomic imprinting in mammals: emerging ...
*  Sex-limited genes
Genomic imprinting for example, silencing of one parental allele by DNA methylation, for which sex-limited imprinting has been ... Genomic imprinting has been shown to be indistinguishable from non-imprinted systems at the population level in some cases, ... Reik, Wolf; Walter, Jörn (1 January 2001). "Genomic imprinting: parental influence on the genome". Nature Reviews Genetics. 2 ( ... Day, T.; Bonduriansky, R. (1 August 2004). "Intralocus Sexual Conflict Can Drive the Evolution of Genomic Imprinting". Genetics ...
*  Anne Ferguson-Smith
Ferguson-Smith is an authority on genomic imprinting and the epigenetic control of genome function in health and disease, and ... Ferguson-Smith, Anne C. (2011). "Genomic imprinting: the emergence of an epigenetic paradigm". Nature Reviews Genetics. 12 (8 ... genomic imprinting, and contributed to its establishment as a model for understanding the epigenetic control of mammalian ... where she initiated molecular studies on genomic imprinting - the process causing genes to be expressed according to their ...
*  Silver-Russell syndrome
Butler, M. G. (2009). "Genomic imprinting disorders in humans: A mini-review". Journal of Assisted Reproduction and Genetics. ... Like other imprinting disorders (e.g. Prader-Willi syndrome, Angelman syndrome, and Beckwith-Wiedemann syndrome), Silver- ... In 10% of the cases the syndrome is associated with maternal uniparental disomy (UPD) on chromosome 7. This is an imprinting ... "Epigenetic mutations of the imprinted IGF2-H19 domain in Silver-Russell syndrome (SRS): Results from a large cohort of patients ...
*  Joomyeong Kim
His research interests include genomic imprinting and epigenetics. Dr. Kim's laboratory is mainly involved in understanding the ... functions and regulatory mechanisms governing genes subject to genomic imprinting. Having previously characterized an imprinted ... Kim J, Ekram MB, Kim H, Faisal M, Frey WD, Huang JM, Tran K, Kim MM, Yu S (2012). "Imprinting control region (ICR) of the Peg3 ... He H, Ye A, Perera BP, Kim J (2017). "YY1's role in the Peg3 imprinted domain". Sci Rep. 7: 6427. doi:10.1038/s41598-017-06817- ...
*  Rex1
"Rex1/Zfp42 as an epigenetic regulator for genomic imprinting". Human Molecular Genetics. 20 (7): 1353-1362. doi:10.1093/hmg/ ... "Coadaptation in mother and infant regulated by a paternally expressed imprinted gene". Proceedings of the Royal Society B: ...
*  PHLDA2
"Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: an introduction". Cancer Res. 59 (7 Suppl): 1743s- ... Lee MP, Feinberg AP (1998). "Genomic imprinting of a human apoptosis gene homologue, TSSC3". Cancer Res. 58 (5): 1052-6. PMID ... 2000). "Retention of imprinting of the human apoptosis-related gene TSSC3 in human brain tumors". Hum. Mol. Genet. 9 (5): 757- ... Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene ...
*  Glypican 3
"Overgrowth syndromes and genomic imprinting: from mouse to man". Clin. Genet. 53 (3): 165-70. doi:10.1111/j.1399-0004.1998. ... 1997). "Analysis of exon/intron structure and 400 kb of genomic sequence surrounding the 5'-promoter and 3'-terminal ends of ...
*  CpG site
Feil R, Berger F (2007). "Convergent evolution of genomic imprinting in plants and mammals". Trends Genet. 23 (4): 192-199. doi ... A 2002 study revised the rules of CpG island prediction to exclude other GC-rich genomic sequences such as Alu repeats. Based ... Methylation, along with histone modification, is central to imprinting. Most of the methylation differences between tissues, or ... or low levels of methylation in that genomic area, perhaps having to do with the regulation of gene expression. Recently a ...
*  Position-effect variegation
Check date values in: ,date= (help) Lloyd, Vett K.; Sinclair, Don A.; Grigliatti, Thomas A. (1999-04-01). "Genomic Imprinting ...
*  Ube3a-ATS
Chamberlain, S. J.; Lalande, M. (2010). "Angelman Syndrome, a Genomic Imprinting Disorder of the Brain". Journal of ... Insights into genomic imprinting and neurodevelopmental phenotypes". Trends in Neurosciences. 34 (6): 293-303. doi:10.1016/j. ... "Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes". Proceedings of ... For the most part, it is thought that at least some type of Ube3a-ATS is expressed in CNS cells that are imprinted, such as ...
*  H19 (gene)
Genomic imprinting is surmised to have arisen due to the conflicting interests of maternal and paternal genes within a ... Moore T, Haig D (February 1991). "Genomic imprinting in mammalian development: a parental tug-of-war". Trends Genet. 7 (2): 45- ... 2009). "H19 acts as a trans regulator of the imprinted gene network controlling growth in mice". Development. "H19: imprinted ... H19 contains a differentially methylated region that is also an imprinting control region. This imprinting control region is ...
*  Genetic disorder
Genomic imprinting and uniparental disomy, however, may affect inheritance patterns. The divisions between recessive and ...
*  Polar overdominance
More and more studies have identified QTL that show evidence of genomic imprinting in farm animals other than sheep. After ... Lawson, Heather A.; Cheverud, James M.; Wolf, Jason B. (2013-09-01). "Genomic imprinting and parent-of-origin effects on ... The imprinted DLK1-GTL2 in sheep is homologous to the DLK1 gene in humans, and includes the callipyge locus. There has been ... Imprinting (genetics) MEG3 - a gene occasionally expressed through polar overdominance Bidwell, C. A.; Waddell, J. N.; Taxis, T ...
*  DNA methyltransferase
DNMT3L is expressed during gametogenesis when genomic imprinting takes place. The loss of DNMT3L leads to bi-allelic expression ... DNMT3L contains DNA methyltransferase motifs and is required for establishing maternal genomic imprints, despite being ...
*  PRC2
... is required for initial targeting of genomic region (PRC Response Elements or PRE) to be silenced, while PRC1 is required ... PRC2 has a role in X chromosome inactivation, in maintenance of stem cell fate, and in imprinting. Aberrant expression of PRC2 ...
*  Empathizing-systemizing theory
According to the imprinted brain theory there could be a mismatch and more severe problems when extreme genomic imprinting ... This is argued to be due to imbalanced genomic imprinting. ... The imprinted brain theory is a somewhat similar although not ...