Genetic engineering
... genetic engineering has the potential to cure genetic diseases through gene therapy. The same techniques that are used to ... Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an ... Gene therapy is the genetic engineering of humans, generally by replacing defective genes with effective ones. Clinical ... Genetic engineering is a process that alters the genetic structure of an organism by either removing or introducing DNA, or ...
Genetic engineering techniques
... perspectives and challenges for gene therapy". Current Gene Therapy. 11 (1): 11-27. doi:10.2174/156652311794520111. PMC 3267165 ... Traditional methods of genetic engineering generally insert the new genetic material randomly within the host genome. This can ... "The process of genetic modification". Nicholl ST (29 May 2008). An Introduction to Genetic Engineering. Cambridge University ... List of genetic engineering software: software to code the genetic modifications Mutagenesis (molecular biology technique) Root ...
Parent-child interaction therapy
Genetic Psychology Monographs. 75 (1): 43-88. PMID 6032134. Robinson, Elizabeth A; Eyberg, Sheila M (1981). "The dyadic parent- ... It uses a unique combination of behavioral therapy, play therapy, and parent training to teach more effective discipline ... Parent-child interaction therapy (PCIT) is an intervention developed by Sheila Eyberg (1988) to treat children between ages 2 ... Choate, Molly L; Pincus, Donna B; Eyberg, Sheila M; Barlow, David H (2005). "Parent-child interaction therapy for treatment of ...
Genetic vaccine
In: Human gene therapy. Band 16, Nummer 3, March 2005, S. 292-298, doi:10.1089/hum.2005.16.292, PMID 15812224. Freda K. ... A genetic vaccine (also gene-based vaccine) is a vaccine that contains nucleic acids such as DNA or RNA that lead to protein ... Genetic vaccines are based on the principle of uptake of a nucleic acid into cells, whereupon a protein is produced according ... Examples of genetic vaccines approved for use in humans include the RNA vaccines tozinameran and mRNA-1273, the DNA vaccine ...
Biotie Therapies
Staff (January 19, 2016). "Acorda Acquires Biotie Therapies for $363 Million". Genetic Engineering & Biotechnology News. New ... Biotie Therapies was formed in the merger of Biotie Therapies Corp. (incorporated in 1998), Oy Contral Pharma Ltd and Carbion ... In 2010 Biotie Therapies all preclinical assets were transferred into a new company, biocrea GmbH, in which Biotie become a ... Biotie Therapies was a Finnish biotechnology and pharmaceutics company that was acquired by Acorda Therapeutics in January 2016 ...
Ingmar Hoerr
Genetic Vaccines and Therapy. 4: 4. doi:10.1186/1479-0556-4-4. ISSN 1479-0556. PMC 1524753. PMID 16732888. S2CID 15324969. ...
Masonic Cancer Center
... genetic mechanisms; immunology; screening, prevention, etiology, and cancer survivorship (SPECS); and transplant biology and ... therapy. About, Masonic Cancer Center, University of Minnesota (accessed August 22, 2016). Celebrating 25 Years of Making Hope ...
HLA-DR4
Therapy. 8 (1): 103. doi:10.1186/ar1886. PMC 1526581. PMID 16542468. Winchester R (1981). "Genetic aspects of rheumatoid ... Yoshizawa K, Ota M, Katsuyama Y, Ichijo T, Matsumoto A, Tanaka E, Kiyosawa K (2005). "Genetic analysis of the HLA region of ... "HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection". Diabetes. 46 ... "HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families". ...
Designer baby
"Gene therapy and genetic engineering". Bitesize. Ali AB (2015). Contemporary Bioethics. Cham Springer. ISBN 978-3-319-18428-9. ... Thus, altering the genetic makeup of an infant is unnatural. In 1984, Pope John Paul II addressed that genetic manipulation in ... "What is gene therapy?". NIH: U.S. National Library of Medicine. Ledford H (2011). "Cell therapy fights leukaemia". Nature. doi: ... Genetic engineering relies on a knowledge of human genetic information, made possible by research such as the Human Genome ...
Hormone replacement therapy
Genetic polymorphism appears to be associated with inter-individual variability in metabolic response to HRT in postmenopausal ... Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of ... Hormone therapy Androgen replacement therapy Transgender hormone therapy Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH ... estrogen-only therapy or estrogen therapy with a progestogen may be safer options than combined systemic therapy. In women who ...
Cell therapy
"Scaling Up Cell Therapy Manufacturing". Genetic Engineering and Biotechnology News. 7 September 2018. "Cell Therapy Process ... Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are ... such as CAR T-cell therapies and allogeneic therapies. Cell and gene therapies require manufacturer and distributors alike to ... Cell therapy can be defined as therapy in which cellular material is injected or otherwise transplanted into a patient. The ...
Theodore Friedmann
"Gene therapy for human genetic disease?." Science 175.4025 (1972): 949-955. Friedmann, Theodore. "Progress toward human gene ... He is a past president of the American Society for Gene Therapy (now the American Society for Gene and Cell Therapy). He also ... Theodore Friedmann - Gene Therapy Lab". UC San Diego. Retrieved 17 December 2019. "The Japan Prize Foundation". The Japan Prize ... Theodore Friedmann (born June 16, 1935) is an American researcher most noted for his work in human gene therapy. He was born in ...
Bacterial therapy
"Gene Circuits Empower Next-Generation Cell and Gene Therapies". GEN - Genetic Engineering and Biotechnology News. 1 February ... Microbial-based cancer therapy may offer an opportunity to address the issue of global cancer therapy disparity and introduce ... Bacterial therapy is the therapeutic use of bacteria to treat diseases. Bacterial therapeutics are living medicines, and may be ... The design of genetic circuits may also be influenced by the circuit's effectors, pragmatic concerns regarding inducer ...
Gene therapy for color blindness
As a way to introduce new genetic information to change a person's phenotype, a gene therapy for color blindness is open to the ... Color vision Gene therapy Achromatopsia Color blindness Gene therapy of the human retina Stem cell therapy for macular ... Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color ... It is uncertain how the quality of life will improve (or worsen) after the therapy. The gene therapy for converting dichromats ...
Biological therapy for inflammatory bowel disease
... is to use a specific patient's biochemical or genetic profile to predict how a patient will respond to a biological therapy. ... TNF inhibiting biological therapies were initially used in IBD patients who weren't responding to conventional therapy. They ... Even so, biologic therapy still has its faults such as high cost and risk of side effects. A lot of research is being done in ... Biological therapy has found a niche in the management of cancer, autoimmune diseases, and diseases of unknown cause that ...
Therapeutic interfering particle
Tanner EJ, Kirkegaard KA, Weinberger LS (May 2016). "Exploiting Genetic Interference for Antiviral Therapy". PLOS Genetics. 12 ... As such, several VLP-based therapy proposals for influenza and other viruses that do not satisfy these criteria are DIPs, but ... Weinberger LS, Schaffer DV, Arkin AP (September 2003). "Theoretical design of a gene therapy to prevent AIDS but not human ... This program led to renewed interest in the concept of interfering particles as therapies with the development of technologies ...
Junctional epidermolysis bullosa (veterinary medicine)
Genetic testing for the disorder is highly recommended among breeding programs for the Draft horse and Saddlebred breeds to ... Ames: Blackwell Science.[page needed] Robinson, N. Edward (2003). Current Therapy in Equine Medicine. St. Louis: Elsevier ... JEB is the result of a genetic mutation that inhibits protein production that is essential for skin adhesion. Therefore, ... Science.[page needed] "Testing for Genetic Diseases." Equus 353. pp 42-43.[verification needed] Berman, Kevin (November 20, ...
Clark Moustakas
Moustakas, C. (1963). Verbatim dialogue of a mother and child in therapy. Genetic Psychology Monographs, 67, 3-43. Moustakas, C ... Moustakas, C. (1982). Emotional adjustment and the play therapy process. In G.L. Landreth (Ed.), Play therapy: Dynamics of the ... In 1953 he wrote his first book, Children in Play Therapy. In 1956 he compiled Publication of The Self, the result of the ... Moustakas, C. (1975). Who will listen?: Children and parents in play therapy. New Rev. 11/11/2010 3 York, NY: Ballantine Books ...
Martha Clokie
"Phage Therapy: Turning the Tables on Bacteria". genengnews.com. GEN - Genetic Engineering and Biotechnology News. 2019-03-06. ... Ghosh, Pallab (2017-06-08). "Therapy could stop superbugs on farms". Retrieved 2019-11-16. Bacteria-killing viruses could ... Therapy, Applications and Research. Clokie was awarded a Grand Challenges exploration fund award from the Bill & Melinda Gates ...
Marcin Kortylewski
"Molecular Therapy - Nucleic Acids editorial board contacts". "SITC Communications Committee". www.sitcancer.org. Retrieved 2023 ... Labant, MaryAnn (2014-06-15). "Therapeutic siRNA Interventions". Genetic Engineering & Biotechnology News. 34 (12): 1, 18-19. ... "Outstanding New Investigator Awards , ASGCT - American Society of Gene & Cell Therapy , ASGCT - American Society of Gene & Cell ... granted based on the contributions to the field of gene and cell therapy. He received the award specifically for his work on " ...
Mark Huyser-Wierenga
"New Gene Therapy trial set to help people with genetic eye diseases". Exchange Magazine. Retrieved May 15, 2020.[dead link] ... "Gene therapy may stop genetic eye disease". Radio Canada International. October 13, 2013. Retrieved May 15, 2020. - " ... Huyser-Wierenga who coauthored papers annually between 1989 and 1993 in the fields of neuro-oncology and radiation therapy. The ...
Mitochondrial replacement therapy
Assisted reproduction via MRT involves preimplantation genetic screening of the mother, preimplantation genetic diagnosis after ... removing nuclear genetic material from the recipient egg or fertilized egg and inserting the nuclear genetic material into the ... The therapy is approved for use in the United Kingdom. A second application is to use autologous mitochondria to replace ... One of the first children, a boy, was born to a 34-year-old woman in January 2017, and genetic test results were reported as ...
Gene therapy for epilepsy
A potential obstacle to clinical translation of gene therapy is that viral vector-mediated manipulation of the genetic make-up ... Gene therapy is being studied for some forms of epilepsy. It relies on viral or non-viral vectors to deliver DNA or RNA to ... Successful gene therapy using lentiviral delivery of KCNA1 has been reported in a rodent model of focal motor cortex epilepsy. ... Gene therapy with a modified potassium channel delivered using either a non-integrating lentivector that avoids the risk of ...
Pharmacogenomics
As the cost per genetic test decreases, the development of personalized drug therapies will increase. Technology now allows for ... "designed to help clinicians understand HOW available genetic test results should be used to optimize drug therapy, rather than ... or from whom genetic information should be masked. Rigorous protection and masking of genetic information is argued to impede ... In particular, genetic deregulations affecting genes coding for DPD, UGT1A1, TPMT, CDA and CYP2D6 are now considered as ...
Cancer biomarker
Impact of Genetic Targets on Cancer Therapy. Advances in Experimental Medicine and Biology. Vol. 779. pp. 145-164. doi:10.1007/ ... May 2007). "Effective therapy of murine models of human leukemia and lymphoma with radiolabeled anti-CD30 antibody, HeFi-1". ... Vrbic S, Pejcic I, Filipovic S, Kocic B, Vrbic M (Jan-Mar 2013). "Current and future anti-HER2 therapy in breast cancer". ... Genetic, epigenetic, proteomic, glycomic, and imaging biomarkers can be used for cancer diagnosis, prognosis, and epidemiology ...
Kenneth R. Chien
"AstraZeneca, SWIBCo Launch Stem Cell Cardiovascular Therapy Collaboration". Genetic Engineering and Biotechnology news. 7 May ... Molecular Therapy. 26 (7): 1644-1659. doi:10.1016/j.ymthe.2018.02.012. PMC 6035340. PMID 29606507. S2CID 4569919. Gan, Li-Ming ...
Genogram
... genetic research, education, and many more. Some practitioners in personal and family therapy use genograms for personal ... Ahnentafel Cousin chart (Table of consanguinity) Eco-map Genetic genealogy#Genetic similarity among relatives (for general ... Australian and New Zealand Journal of Family Therapy. Dr. Wentian Li (16 March 2012). "An Alphabetic List of Genetic Analysis ... In family therapy, genograms are used to study and record relationship patterns between family members and the individual ...
Baxalta
Genetic Engineering & Biotechnology News (Paper). 35 (7): 10. "Baxter Expands Cancer Therapies With $900M Oncaspar Buy". law360 ... Staff (1 April 2015). "Baxter Acquires SuppreMol and Its Immunoregulatory Therapy Pipeline". News: Industry Watch. ...
Self-experimentation in medicine
"Video: Biohacker documents his own DIY gene therapy". Genetic Literacy Project. 2018-02-19. Retrieved 2022-01-01. Pearlman Alex ... Self-experimentation with gene therapies have been reported. Every gene therapy has a unique risk of harm, including the risk ... Smalley E (2018). "FDA warns public of dangers of DIY gene therapy". Nat Biotechnol. 36 (2): 119-120. doi:10.1038/nbt0218-119. ... Examples of potential risks for some gene therapies include tissue damage and an immune response to foreign DNA, among many ...
Spongy degeneration of the central nervous system
Bakewell J (August 2007). "Choosing support equipment in children's therapy". International Journal of Therapy and ... Genetic screening reveals that around 1 in 40 healthy Jews are carriers and the incidence of this disease in this population is ... This therapy involves replacing the mutant gene of the disease with a fully functional gene using a vector, which transports ... It belongs to a group of genetic disorders known as leukodystrophies, where the growth and maintenance of myelin sheath in the ...