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*  Decellularization of porcine heart valve
Genetic predisposition for valvular disease is uncommon. Xenogeneic antigens are recognized as foreign by the human body and ... Valvular disease is caused primarily by valvular lesions stemming from infections, especially rheumatic fever (Streptococceus ... that can then be used for tissue engineering and valve replacement in humans inflicted with valvular disease. Decellularized ...
*  Julius Caesar
Caesar possibly had a genetic predisposition for cardiovascular disease. The Roman historian Suetonius, writing more than a ... who prefers Ménière's disease; and O. Temkin, The Falling Sickness: A History of Epilepsy from the Greeks to the Beginnings of ...
*  Lichen sclerosus
Several risk factors have been proposed, including autoimmune diseases, infections and genetic predisposition. There is ... vitiligo and thyroid disease. Both bacterial as well as viral pathogens have been implicated in the etiology of LS. A disease ... In males, the disease may take the form of whitish patches on the foreskin and its narrowing (preputial stenosis), forming an " ... The disease can last for a considerably long time. Occasionally, "spontaneous cure" may ensue, particularly in young girls. ...
*  Primary biliary cholangitis
A genetic predisposition to disease has been thought to be important for some time. Evidence for this includes cases of PBC in ... in more advanced disease Enlarged spleen in more advanced disease Oesophageal varices in more advanced disease Hepatic ... The cause of the disease is attributed to an immunological basis for the disease, making it an autoimmune disorder. It results ... are found in early disease. Elevations in bilirubin occur in advanced disease. Antimitochondrial antibodies are the ...
*  Coxsackievirus-induced cardiomyopathy
... a genetic predisposition to viral heart disease". Nature Medicine. 8 (8): 872-7. doi:10.1038/nm737. PMID 12118246. Nishtala, K ... 1. The amount of virally infected cardiomyocytes varies in different stages of the disease. In a mouse model, at the acute ... In addition to the genetic defects in dystrophin or other cytoskeletal proteins, a subset of dilated cardiomyopathy is linked ...
*  Nicotine gum
"Smoking Significantly Increases Risk of Alzheimer's Disease Among Those Who Have No Genetic Predisposition". Retrieved 2009-12- ... Nicotine has been shown to delay the onset of Parkinson's disease in studies involving monkeys and humans. A study has shown a ... Chewing nicotine gum may increase the risk of heart disease, although this is still debated. Nicotine is a vasoconstrictor; it ... There is evidence that nicotine has the potential to prevent and treat Alzheimer's disease. ...
*  White dot syndromes
Some suggest a genetic predisposition to the disease, while others postulate an abnormal immune response to a virus. Multiple ... common autoimmune and inflammatory diseases arise from combinatorial interactions of common non-disease specific loci, disease ... White spot syndromes of the retina: a hypothesis based on the common genetic hypothesis of autoimmune/inflammatory disease. ... Becker, K. G. (2001). The common genetic hypothesis of autoimmune/inflammatory disease. Curr Opin Allergy Clin Immunol, 1(5), ...
*  Genetic predisposition
In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, which may eventually ... Behaviors displayed by animals can be influenced by genetic predispositions. Genetic predisposition towards certain human ... Genetic testing is able to identify individuals who are genetically predisposed to certain diseases. Predisposition is the ... A genetic predisposition is a genetic characteristic which influences the possible phenotypic development of an individual ...
*  OpenSNP
... have discovered that there is a correlation between certain SNPs and genetic predispositions such as Mendelian disease. The ... "Maybe there are people who are interested in publishing their genetic information on the web to make it available, but those ... After receiving his results, he posted them on Github, hoping to find other users willing to share their personal genetic ... Released in September 2011, openSNP is an open source website where users can share their genetic information. Users upload ...
*  Neuroprotection
"Smoking Significantly Increases Risk of Alzheimer's Disease Among Those Who Have No Genetic Predisposition". Retrieved 2009-12- ... Minocyline has been shown to have neuroprotective activity in the CNS for Huntington's disease, Parkinson's disease, ... models of inflammation-involving neurological diseases such as various degenerative diseases including Alzheimer's disease. A ... which is a highly recognized part of cerebral ischemia as well as many neurodegenerative diseases including Parkinson's disease ...
*  Porphyria
Some liver diseases may cause porphyria even in the absence of genetic predisposition. These include hemochromatosis and ... McManus, Linda (2014). Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier. p. 1488. ISBN ... Diseases of Tetrapyrrole Metabolism - Refsum Disease and the Hepatic Porphyrias Archived 4 June 2011 at the Wayback Machine. ... Milder skin disease, such as that seen in VP and HCP, consists of increased skin fragility in exposed areas with a tendency to ...
*  Early-onset Alzheimer's disease
Approximately 13% of the cases of early-onset Alzheimer's are familial Alzheimer's disease, where a genetic predisposition ... Williamson, Jennifer; Goldman, Jill; Marder, Karen S. (2009). "Genetic Aspects of Alzheimer Disease". The Neurologist. 15 (2): ... Early-onset Alzheimer's disease, also called early-onset Alzheimer's, or early-onset AD, is Alzheimer's disease diagnosed ... Familial Alzheimer's disease (FAD) or early onset familial Alzheimer's disease (EOFAD) is an uncommon form of Alzheimer's ...
*  Rod Broadway
... although research suggests that genetic predisposition might be a part of the disease. Broadway lost his mother, his wife, and ... The disease primarily attacks women from ages 30 to 50. Doctors do not know the origin of scleroderma, ... In June 2004, Broadway's wife, Dianne, died after 14 years of battling scleroderma, a rheumatic disease of the connective ...
*  Klaus Lauer
MS is generally considered a multifactorial disease, in which genetic predispositions and environmental triggers combine to ... The possible influence of occupation on the risk of disease". Acta Neurologica Scandinavica. 72 (4): 397-402. doi:10.1111/j. ... The influence of urban and rural environment on disease risk". Acta Neurologica Scandinavica. 72 (4): 403-6. doi:10.1111/j.1600 ...
*  Kikuchi disease
Human leukocyte antigen class II genes are more frequent in patients with Kikuchi disease, suggesting a genetic predisposition ... Kikuchi's disease is a very rare disease mainly seen in Japan. Isolated cases are reported in North America, Europe, and Asia. ... Some studies have suggested a genetic predisposition to the proposed autoimmune response. Several infectious candidates have ... Kikuchi disease or Kikuchi-Fujimoto disease was described in 1972 in Japan. It is also known as histiocytic necrotizing ...
*  Graves' disease
... disease, more robust clinical data are needed for a firm conclusion. A genetic predisposition for Graves' disease is seen, with ... Begbie's disease, Flajani's disease, Flajani-Basedow syndrome, and Marsh's disease. These names for the disease were derived ... disease and Graves disease are variant stylings for the same term. Ayaka, Japanese singer, was diagnosed with Graves' disease ... disease. Graves' disease has also been called exophthalmic goiter. Less commonly, it has been known as Parry's disease, ...
*  Electroneuronography
The etiology of this disease is currently unknown, but hypotheses include infections, genetic predisposition, environmental ... Electroneuronography is used as a basis for a physician's course of action in managing disease. A doctor may opt for continued ...
*  Pyloric stenosis
... and there is a genetic predisposition for the disease. It is commonly associated with people of Scandinavian ancestry, and has ... Pyloric stenosis seems to be multifactorial, with some genetic and some environmental components. It is four times more likely ... Georgoula, C; Gardiner, M (August 2012). "Pyloric stenosis a 100 years after Ramstedt". Archives of Disease in Childhood. 97 (8 ... Archives of Disease in Childhood. 92 (3): 271-3. doi:10.1136/adc.2006.110007. PMC 2083424 . PMID 17337692. Archived from the ...
*  Keratoconus
A genetic predisposition to keratoconus has been observed, with the disease running in certain families, and incidences ... As the disease worsens special contact lenses may be required. In most people the disease stabilizes after a few years without ... any of which may form the trigger for the onset of the disease. Once initiated, the disease normally develops by progressive ... The disease can, however, present or progress at any age; in rare cases, keratoconus can present in children or not until later ...
*  Katherine Sanford
... she created a test that could differentiate people with a genetic predisposition for cancer from those with Alzheimer's disease ... In 1985, she designed a test that could recognized genetic predisposition for cancer. Building on this idea in the 90s, ... This allowed the advancement of research on metabolic and genetic features of the clone cell. Prior to her discovery, tissue ... This patent was a process patent for detecting genetic susceptibility to cancer, involving the frequency of gaps and breaks in ...
*  Megacolon
A genetic predisposition to Hirschsprung's disease has been linked to chromosome 13 where a missense mutation at an ... systemic and metabolic diseases Also called Hirschsprung's disease, it is a congenital disorder of the colon in which nerve ... Inflammatory bowel diseases. 10 (3): 245-50. PMID 15290919. Koeberle F (1963). "Enteromegaly and cardiomegaly in Chagas disease ... in the other type of inflammatory bowel disease, Crohn's disease). Its mechanism is incompletely understood. It is probably due ...
*  Hoof wall separation disease
The disease has been found in animals with a frameshift mutation variety of the protein Serpin B11. Genetic predisposition may ... Hoof wall separation disease, (HWSD), is an autosomal recessive genetic hoof disease in horses. Research is being carried out ... HWSD is often confused with white line disease (WLD) by those people who have no experience or knowledge of this genetic ... The disease has been found in Connemara ponies and was earlier referred to as Hoof Wall Separation Syndrome, HWSS. The disease ...
*  The Environmental Determinants of Diabetes in the Young
... genetic predisposition is not the only factor in development of the disease. An increasing body of evidence, including rising ... The study follows children at high genetic risk for T1D from birth to 15 years of age. Although genetic markers for Type 1 ... Potential TEDDY subjects were identified at birth by genetic screening of the HLA-DR/DQ loci, which are considered to be highly ... Children followed in the TEDDY study are diagnosed with Type 1 diabetes at an early stage of disease. Pediatric Diabetes. 2013 ...
*  Pancolitis
... although physicians currently believe that autoimmune diseases and genetic predispositions might play a role in its progress. ... Genes that are known to put individuals at risk for Crohn's disease have been shown to also increase risk of other IBD ... However, in this case it can further expose the patient to other diseases due to the compromised immune system. A final option ... Pancolitis is a kind of inflammatory bowel disease (IBD) that affects the entire internal lining of the colon. The precise ...
*  Autoimmunity
Several mechanisms are thought to be operative in the pathogenesis of autoimmune diseases, against a backdrop of genetic ... predisposition and environmental modulation. It is beyond the scope of this article to discuss each of these mechanisms ... Although this route to autoimmune disease may underlie various degenerative disease states, no diagnostics for this disease ... Addison's disease Gastrointestinal: Coeliac disease, Crohn's disease, Pernicious anaemia Dermatologic: Pemphigus vulgaris, ...
*  Predictive medicine
With careful usage, predictive medicine methods such as genetic screens can help diagnose inherited genetic disease caused by ... genetic predispositions. Colby, B. Outsmart your genes. Penguin, 2010. Collins, F. The Language of Life: DNA and the Revolution ... Aside from genetic testing, predictive medicine utilizes a wide variety of tools to predict health and disease, including ... Therefore, in many diseases, having the faulty gene still does not necessarily mean someone will get the disease. Common, ...