The function of the auxiliary gene vif is not fully known. The vif gene product, a 29 kDa protein, induces a weak immune ... An auxiliary gene, vif (viral infectivity factor), is also encoded. However, the number and role of auxiliary genes varies by ... Deletion experiments have demonstrated that the vif gene is essential for infectivity. Though it does not produce severe ... "The vif gene of maedi-visna virus is essential for infectivity in vivo and in vitro". J. Virol. 318 (1): 350-359. doi:10.1016/j ...

Lake JA, Carr J, Feng F, Mundy L, Burrell C, Li P (February 2003). "The role of Vif during HIV-1 infection: interaction with ... PMF1 and NRF2 work together to transcript the SAT1 gene. The SAT1 gene is 3,069 base pairs long. There are 171 amino acids and ... "Entrez Gene: SAT1 spermidine/spermine N1-acetyltransferase 1". "SAT1 Gene". GeneCards. Pegg AE (June 2008). "Spermidine/ ... KFSDX gene. This gene is located on the X chromosome in the region Xp22.1. The primer extension analysis indicated that the ...

Other accessory genes include vif (viral infectivity factor), tat (transcription activator), and rev (protein expression ... These genes are surrounded by and 5' and 3' LTR. It also contains at least five non-structural accessory gene open reading ... The genome contains the usual retroviral structural genes including gag, pol, and env. ... "Construction and Molecular Analysis of Gene Transfer Systems Derived from Bovine Immunodeficiency Virus". J. Virol. 75 (7): ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The gene PSMD7 encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. The human ... "Entrez Gene: PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)". "Uniprot: P51665 - PSMD7_HUMAN ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMB3 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit ... The gene has 6 exons and locates at chromosome band 17q12. The human protein proteasome subunit beta type-3 is 23 kDa in size ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... appears to be particularly important for APOBEC3G interactions with Vif because a D128K point mutation prevents Vif-dependent ... Vif interacts with APOBEC3G and triggers the ubiquitination and degradation of APOBEC3G via the proteasomal pathway. On the ... However, Vif counteracts this antiretroviral factor, enabling production of viable and infective HIV-1 virions in the presence ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator base. The proteasome and its subunits are of clinical significance ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... Moreover, the UPS regulates the degradation of tumor suppressor gene products such as adenomatous polyposis coli (APC) in ... Articles with short description, Short description is different from Wikidata, Genes on human chromosome 14). ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit beta2 (proteasome ... This gene PSMB10 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The human PSMD1 gene has 25 exons and locates at chromosome band 2q37.1. The human protein 26S proteasome non-ATPase regulatory ... The gene PSMD1 encodes the largest non-ATPase subunit of the 19S regulator base, which is responsible for substrate recognition ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. The proteasome ... 26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene. The 26S proteasome is ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199-207. doi:10.1016/0378-1119(94)90293-3. PMID ... The gene PSMC4 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like ... The human PSMC3 gene has 11 exons and locates at chromosome band 19q13.11-q13.13. The human protein 26S protease regulatory ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator. The proteasome and its subunits are of clinical significance for ... Gene expression levels of the proteasomal subunits (PSMA1, PSMA5, PSMB4, PSMB5 and PSMD1) were investigated in 80 patients with ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Vif actually exploits our intrinsic immunity, titrating the degree of APOBEC3G polyubiquitination in order to augment the ... APOBEC3G expression is disrupted by the HIV vif protein which induces its degradation through the ubiquitin/proteasome system. ... mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMB6 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-Jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The human gene contains 6 exons and is located at chromosome band 17p13. The human protein proteasome subunit beta type-6 is 22 ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative ... "Entrez Gene: PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)". Goff SP (Aug 2003). "Death by deamination: a ... Proteasome inhibitor PI31 subunit is a protein that in humans is encoded by the PSMF1 gene. The 26S proteasome is a ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The gene PSMD4 encodes one of the non-ATPase subunits of the 19S regulator base, subunit Rpn10. Pseudogenes have been ... The human PSMD4 gene has 10 exons and locates at chromosome band 1q21.3. The human protein 26S proteasome non-ATPase regulatory ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) ... "Entrez Gene: PSME4 proteasome (prosome, macropain) activator subunit 4". Goff SP (Aug 2003). "Death by deamination: a novel ... Lecossier D, Bouchonnet F, Clavel F, Hance AJ (May 2003). "Hypermutation of HIV-1 DNA in the absence of the Vif protein". ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMC1 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The human PSMC1 gene has 11 exons and locates at chromosome band 14q32.11. The human protein 26S protease regulatory subunit 4 ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Gene. 203 (2): 241-50. doi:10.1016/S0378-1119(97)00524-6. PMID 9426256. "Entrez Gene: PSMD12 proteasome (prosome, macropain) ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. The proteasome ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Gene Structure and Expression. 1219 (2): 361-8. doi:10.1016/0167-4781(94)90060-4. PMID 7918633. "Entrez Gene: PSMB2 proteasome ... The gene PSMB2 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit ... The gene has 7 exons and locates at chromosome band 1p34.2. The human protein proteasome subunit beta type-2 is 23 kDa in size ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMA2 encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Using FISH, the human gene HC3 ( ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... Okumura K, Nogami M, Taguchi H, Hisamatsu H, Tanaka K (May 1995). "The genes for the alpha-type HC3 (PMSA2) and beta-type HC5 ( ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646- ... The PSMA4 gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. The gene has 9 exons and locates ... Gene Structure and Expression. 1089 (1): 95-102. doi:10.1016/0167-4781(91)90090-9. PMID 2025653. "Entrez Gene: PSMA4 proteasome ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. ... Gene expression levels of the proteasomal subunits (PSMA1, PSMA5, PSMB4, PSMB5 and PSMD1) were investigated in 80 patients with ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... 26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene. The proteasome and its ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... This gene PSMB4 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit ... The gene has 7 exons and locates at chromosome band 1q21. The human protein proteasome subunit beta type-2 is 23 kDa in size ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three ... "Entrez Gene: PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)". Rual JF, Venkatesan K, Hao T, Hirozane- ... Proteasome activator complex subunit 2 is a protein that in humans is encoded by the PSME2 gene. The 26S proteasome is a ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... is an enzyme that in humans is encoded by the PSMD2 gene. The gene PSMD2 encodes a non-ATPase subunit of the 19S regulator base ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... The gene PSMD2 encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMB5 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... "Entrez Gene: PSMB5 proteasome (prosome, macropain) subunit, beta type, 5". Coux O, Tanaka K, Goldberg AL (1996). "Structure and ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The human PSMB7 gene has 8 exons and locates at chromosome band 9q34.11-q34.12. The gene PSMB7 encodes a member of the ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... Targeting the PSMB7 gene, to down-regulate PSMB7 protein, may overcome resistance to 5-FU and thus a possible new approach to ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes one of the non-ATPase subunits of the 19S regulator lid. The proteasome and its subunits are of clinical ... 26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene. The 26S proteasome is ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... PSME3 human gene location in the UCSC Genome Browser. PSME3 human gene details in the UCSC Genome Browser. v t e (Articles with ... "Characterization of the mouse PA28 activator complex gene family: complete organizations of the three member genes and a ... This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... The gene PSMA7 encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This gene has 7 exons and ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... "Entrez Gene: PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7". Dächsel JC, Lücking CB, Deeg S, Schultz E, Lalowski ...

"Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... Accordingly, gene expression by degradation of transcription factors, such as p53, c-jun, c-Fos, NF-κB, c-Myc, HIF-1α, MATα2, ... This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. ... "Entrez Gene: PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10". Kleiger G, Mayor T (Jun 2014). "Perilous ...