Görke B, Vogel J (2008). "Noncoding RNA control of the making and breaking of sugars". Genes Dev. 22 (21): 2914-2925. doi: ... The GlmY RNA gene is present in Escherichia coli, Shigella flexneri, Yersinia pestis and Salmonella species, where it is found ... The GlmY RNA (formally known as tke1) family consists of a number of bacterial RNA genes of around 167 bases in length. ... Genes & Development. 27 (5): 552-564. doi:10.1101/gad.210112.112. PMC 3605468. PMID 23475961. Hobbs EC, Astarita JL, Storz G ( ...
Page for mir-451 microRNA precursor family at Rfam "MicroRNA MIR451 family (MIR451) Gene group". HUGO Gene Nomenclature ... Godlewski J, Bronisz A, Nowicki MO, Chiocca EA, Lawler S (2010). "microRNA-451: A conditional switch controlling glioma cell ... MicroRNAs function to regulate the expression levels of other genes by several mechanisms. miR-451 regulates the drug- ... Genes Dev. 24 (15): 1620-1633. doi:10.1101/gad.1942110. PMC 2912560. PMID 20679398. Patrick DM, Zhang CC, Tao Y, Yao H, Qi X, ...
... human gene details in the UCSC Genome Browser. This article incorporates text from the United States National Library of ... Wolffe AP (May 1997). "Transcriptional control. Sinful repression". Nature. 387 (6628): 16-17. doi:10.1038/387016a0. PMID ... "Entrez Gene: HDAC6 histone deacetylase 6". Krishnamurthy K, Wang G, Silva J, Condie BG, Bieberich E (February 2007). "Ceramide ... Mutations in this gene have been associated to Alzheimer's disease. Over expression of this protein correlates with ...
... they cannot exhibit control over their target genes. The main signalling processes that are affected by p53 are apoptosis and ... Pin1 affects many other genes in the form of gene silencing through the disruption of cell pathways, making it important in ... MLL1 is a multiprotein complex that regulates gene expression and chromosomal translocations involving this gene often lead to ... "Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1". Genes & Development. 26 (17): ...
40% of the genes found to be regulated by Bck2 were also targets of regulation by Mcm1. Mcm1 activates M/G1 genes through ... Schmoller KM, Turner JJ, Kõivomägi M, Skotheim JM (October 2015). "Dilution of the cell cycle inhibitor Whi5 controls budding- ... Another study showed gene regulation by Bck2 may be ECB-dependent. BCK2 overexpression leads to CLN3 and SWI4 upregulation. ... Overexpression of Bck2 in Swi6-null cells resulted in changes in expression of genes known to be regulators of the cell cycle, ...
"Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization". Genes & Development. 26 (2): 114-119. doi ... The chaperone code refers to post-translational modifications of molecular chaperones that control protein folding. Whilst the ... the chaperone code controls how proteins are folded to produce a functional proteome. The chaperone code refers to the ... co-chaperones that control all aspects of life. Site-specific phosphorylation of chaperone proteins can affect their activity. ...
1998). "Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis". Genes Dev. 12 (19 ... "Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)". Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, ... Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene. PLRG1 has been shown to interact with CDC5L. ... 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome ...
Ruaud AF, Thummel CS (July 2008). "Serotonin and insulin signaling team up to control growth in Drosophila". Genes & ... March 2005). "Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced ... The 5-HTTLPR gene codes for the number of serotonin transporters in the brain, with more serotonin transporters causing ... Serotonin had only a short-term effect on the level of some locomotor activities and was not involved in the control of ...
Pugh BF (September 2000). "Control of gene expression through regulation of the TATA-binding protein". Gene. 255 (1): 1-14. doi ... "Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression". Genes & ... "Entrez Gene: TBP TATA box binding protein". McCulloch V, Hardin P, Peng W, Ruppert JM, Lobo-Ruppert SM (August 2000). " ... TBP is a member of a small gene family of TBP-related factors. The first TBP-related factor (TRF/TRF1) was identified in the ...
... caretaker genes), as well as in genes that are directly controlling cellular proliferation (gatekeeper genes). Genetic ... One such locale is the Ig genes. In a pre-B cell, the region consists of all V, D, and J segments. During development of the B ... An example is the Saccharomyces pombe gene rad9 which arrests the cells in late S/G2 phase in the presence of DNA damage caused ... While a mutation or epimutation in a DNA repair gene itself would not confer a selective advantage, such a repair defect may be ...
Massagué J, Chen YG (March 2000). "Controlling TGF-beta signaling". Genes & Development. 14 (6): 627-44. doi:10.1101/gad.14.6. ... Kyoto Encyclopedia of Genes and Genomes -TGF beta signaling pathway map Netpath - A curated resource of signal transduction ... Follistatin also is implicated in prostate cancers where mutations in its gene may preventing it from acting on activin which ... complexes accumulate in the nucleus where they act as transcription factors and participate in the regulation of target gene ...
Gene orientation depends on the direction of transcription and can be of three types: head-to-head, head-to-tail and tail-to- ... Without cohesin, the cell would be unable to control sister chromatid segregation since there would be no way of ensuring ... Cohesin binding along the chromosomal DNA is considered to be dynamic and its location changes based on gene transcription, ... There are three possible scenarios: Cohesin location is influenced by the orientation of neighboring genes and it is most ...
TAS gene family numbers do not generally indicate orthology, e.g. the moss TAS1 gene family does not share an ancestor gene ... "DRB4-dependent TAS3 trans-acting siRNAs control leaf morphology through AGO7". Curr. Biol. 16 (9): 927-32. doi:10.1016/j.cub. ... repressing the expression of genes that are the same as or have a lot of resemblance to the genes from which they derive. It ... which means that the genes they target for cleavage and repression do not have much resemblance to the genes from which the ...
"Entrez Gene: MTOR associated protein". "UniProtKB - Q9BVC4 (LST8_HUMAN)". Kakumoto K, Ikeda J, Okada M, Morii E, Oneyama C (23 ... Inoki K, Ouyang H, Li Y, Guan KL (2005). "Signaling by target of rapamycin proteins in cell growth control". Microbiol. Mol. ... 2002). "Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control". Mol. Cell. 10 ... v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome 16, All stub ...
Tsai RY, McKay RD (Dec 2002). "A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells". Genes Dev ... Liu SJ, Zhang ZH, Zhang DQ, Sui XM, Liu YJ, Cai ZW, Yuan XY, Sun LQ, Hu GF, Liu RL (2006). "Gene profiling after knocking-down ... Han C, Zhang X, Xu W, Wang W, Qian H, Chen Y (2005). "Cloning of the nucleostemin gene and its function in transforming human ... Guanine nucleotide-binding protein-like 3, also known as nucleostemin, is a protein that in humans is encoded by the GNL3 gene ...
The rate of nonsense mutations is variable from gene-to-gene and tissue-to-tissue but gene silencing occurs in every patient ... Isken, Olaf; Maquat, Lynne E. (2007-08-01). "Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function ... The ALK1 gene, a part of the TGF-B signaling family, was found to have been mutated while also down-regulating the SMAD8 gene ... For example, a nonsense mutation occurring in a gene encoding a protein can cause structural or functional defects in the ...
Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene. This gene encodes a member of the Argonaute ... Carmell MA, Xuan Z, Zhang MQ, Hannon GJ (2002). "The Argonaute family: tentacles that reach into RNAi, developmental control, ... Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K (January 2003). "Short-interfering-RNA-mediated gene silencing in ... It may interact with Dicer1 and play a role in short-interfering-RNA-mediated gene silencing. EIF2C2 has been shown to interact ...
"Entrez Gene: GSK3B glycogen synthase kinase 3 beta". Iwahashi K, Nishizawa D, Narita S, Numajiri M, Murayama O, Yoshihara E, et ... Guo X, Ramirez A, Waddell DS, Li Z, Liu X, Wang XF (January 2008). "Axin and GSK3- control Smad3 protein stability and modulate ... Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is ... Two SNPs at this gene, rs334558 (-50T/C) and rs3755557 (-1727A/T), are associated with efficacy of lithium treatment in bipolar ...
Genes Immun. 14 (5): 336-45. doi:10.1038/gene.2013.29. PMC 3740552. PMID 23698708. O'Brien CA (2010). "Control of RANKL gene ... RANKL is an apoptosis regulator gene, a binding partner of osteoprotegerin (OPG), a ligand for the receptor RANK and controls ... The overall control of bone remodeling is regulated by the binding of RANKL with its receptor or its decoy receptor, ... Since osteoblasts control the regulation of RANKL, the stimulation via cytokines and growth factors will then stimulate ...
Transcription factors control gene expression by interacting with enhancer sequences. The transcription factors pancreas/ ... Bonal C, Herrera PL (2008). "Genes controlling pancreas ontogeny". The International Journal of Developmental Biology. 52 (7): ... Yong HJ, Xie G, Liu C, Wang W, Naji A, Irianto J, Wang YJ (2021). "Gene Signatures of NEUROGENIN3+ Endocrine Progenitor Cells ... Neurogenin-3 (NGN3) is a protein that in humans is encoded by the Neurog3 gene. Neurogenin-3 is a pro-endocrine transcription ...
Genes on human chromosome 14, Webarchive template wayback links, All stub articles, Human chromosome 14 gene stubs). ... FERMT2 is a component of extracellular matrix structures in mammalian cells and is required for proper control of cell shape ... "Entrez Gene: FERMT2". Tu Y, Wu S, Shi X, Chen K, Wu C (April 2003). "Migfilin and Mig-2 link focal adhesions to filamin and the ... It was detected in a screen for epidermal growth factor (EGF)-induced mRNAs and initially named mitogen-inducible gene 2 (Mig-2 ...
Identification of genes involved in cell cycle control, apoptosis, and early development". Cell Cycle Control. Methods in ... "Role of LXRs in Control of Lipogenesis". Genes & Development. 14 (22): 2831-8. doi:10.1101/gad.850400. PMC 317060. PMID ... In 1997, Lustig invented a functional genomics approach to gene discovery and used it to identify a new member of the T-box ... Lustig, KD; Kroll, K; Sun, E; Ramos, R; Elmendorf, H; Kirschner, M (October 1996). "A Xenopus Nodal-Related Gene That Acts in ...
Homeobox protein Hox-B6 is a protein that in humans is encoded by the HOXB6 gene. This gene is a member of the Antp homeobox ... potential candidates for the transcriptional control of the transformed and invasive phenotype". Biochemical Pharmacology. 47 ( ... HOX B6 gene is only expressed in erythoid progenitor cells, which are the precursor to red blood cells used for transport of ... This gene has also been shown to encourage the growth of granulocytes and monocytes, but at the cost of other blood cells. ...
"TEAD mediates YAP-dependent gene induction and growth control". Genes & Development. 22 (14): 1962-71. doi:10.1101/gad.1664408 ... Laloux I, Dubois E, Dewerchin M, Jacobs E (July 1990). "TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene ... Zhao B, Li L, Lei Q, Guan KL (May 2010). "The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version". ... It has been shown in HeLa cells that TEAD2 and SRC induce gene expression. SRF (Serum response factor) and TEAD2 interact ...
Edwards PA, Kennedy MA, Mak PA (April 2002). "LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid ... The human LXRα gene is located on chromosome 11p11.2, while the LXRβ gene is located on chromosome 19q13.3. While the ... "Role of LXRs in control of lipogenesis". Genes Dev. 14 (22): 2831-8. doi:10.1101/gad.850400. PMC 317060. PMID 11090131. Herath ... "Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ". Genes ...
"Mitf regulation of Dia1 controls melanoma proliferation and invasiveness". Genes & Development. 20 (24): 3426-39. doi:10.1101/ ... This gene is a homolog of the Drosophila diaphanous gene and belongs to the protein family of the formins, characterized by the ... Genes on human chromosome 5, All stub articles, Human chromosome 5 gene stubs). ... "Entrez Gene: DIAPH1 diaphanous homolog 1 (Drosophila)". Riento K, Guasch RM, Garg R, Jin B, Ridley AJ (June 2003). "RhoE binds ...
"Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha". Genes & Development. 12 (2): 149-62 ... "Loss of PTEN facilitates HIF-1-mediated gene expression". Genes & Development. 14 (4): 391-6. doi:10.1101/gad.14.4.391. PMC ... The human HIF1A gene encodes for the alpha subunit, HIF1A of the transcription factor hypoxia-inducible factor (HIF1). Its ... Function of HIF1A gene can be effectively examined by siRNA knockdown based on an independent validation. In normal ...
Artificial gene synthesis is the process of synthesizing a gene in vitro without the need for initial template DNA samples. In ... DNA replication machinery is therefore highly controlled in order to prevent collapse when encountering damage. Control of the ... Gene synthesis, however, does not require a DNA template and genes are assembled de novo. DNA synthesis occurs in all ... or gene synthesis - physically creating artificial gene sequences. Though each type of synthesis is very different, they do ...
"Entrez Gene: UBC ubiquitin C". Kimura Y, Tanaka K (June 2010). "Regulatory mechanisms involved in the control of ubiquitin ... UBC gene differs from UBB gene in the number of Ub coding units they contain. Nine to ten Ub units were in the UBC gene. In ... UBC gene is one of the two stress-regulated polyubiquitin genes (UBB and UBC) in mammals. It plays a key role in maintaining ... UBC gene is located at chromosome 12q24.3, consisting of 2 exons. The promoter of the UBC gene contains putative heat shock ...
Isken O, Maquat LE (August 2007). "Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function". Genes ... Gene editing therapies such as CRISPR may also benefit from using mRNA to induce cells to make the desired Cas protein. Since ... The primary RNA transcript of a gene is cleaved at the poly-A addition site, and 100-200 A's are added to the 3' end of the RNA ... siRNA is commonly used in laboratories to block the function of genes in cell culture. It is thought to be part of the innate ...