T-cell receptor alpha locus is a protein that in humans is encoded by the TRA gene, also known as TCRA or TRA@. It contributes ... "Entrez Gene: TRA@ T cell receptor alpha locus". Kenwrick S, Levinson B, Taylor S, et al. (1993). "Isolation and sequence of two ... "The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific ... 1985). "Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer ...
... is a protein that in humans is encoded by the TRAJ56 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: T cell receptor alpha joining 56". Retrieved 2015-09-02. v t e (Articles with short description, Short description ... matches Wikidata, Genes on human chromosome 14, All stub articles, Human chromosome 14 gene stubs, Proteins). ...
T cell receptor alpha variable 12-2 is a protein that in humans is encoded by the TRAV12-2 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: T cell receptor alpha variable 12-2". Retrieved 2018-01-26. v t e (Articles with short description, Short ... description matches Wikidata, Genes on human chromosome 14, All stub articles, Human chromosome 14 gene stubs). ...
"Entrez Gene: THRA thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)". Sakurai A ... "A point mutation of the T3 receptor beta 1 gene in a kindred of generalized resistance to thyroid hormone". Mol. Cell. ... The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for ... Nakai A, DeGroot LJ (June 1990). "Structural analysis of human thyroid hormone receptor beta gene". Mol. Cell. Endocrinol. 71 ( ...
2004). "Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells". Genome Biology. 5 (9): ... Once inside the cell, they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes. ... Note that in males, estrogen is also produced by the Sertoli cells when FSH binds to their FSH receptors. Estrogens are plasma ... On a molecular level estrogen induces the above mentioned effects on cell via acting on intracellular receptors termed ER α and ...
The gene for the alpha subunit is 40 kilobases long and has 12 exons. The receptor, found on pluripotent progenitor cells, ... Genes on human chromosome X, Human gene pages with Wikidata item, Genes on human chromosome Y, Type I cytokine receptors). ... The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to ... The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble ...
1994). "Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5". Cytogenet. Cell Genet. 67 ... This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a ... 1994). "Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c". Biochem ... is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it. There are 3 alpha-1 adrenergic receptor ...
"OMIM Entry - * 180240 - RETINOIC ACID RECEPTOR, ALPHA; RARA". www.omim.org. Retrieved 2021-04-27. "Entrez Gene: retinoic acid ... May 1996). "A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors". Cell. 85 (3 ... Retinoic acid receptor alpha (RAR-α), also known as NR1B1 (nuclear receptor subfamily 1, group B, member 1) is a nuclear ... RARA codes for the nuclear hormone receptor retinoic acid receptor, alpha subtype, a transcription factor. There are another ...
Mandard S, Müller M, Kersten S (2004). "Peroxisome proliferator-activated receptor alpha target genes". Cell. Mol. Life Sci. 61 ... Gene expression profiling studies have indicated that PPAR-alpha target genes number in the hundreds. Classical target genes of ... Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1 ... Together with peroxisome proliferator-activated receptor delta and peroxisome proliferator-activated receptor gamma, PPAR-alpha ...
"The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... Type II cytokine receptors, All stub articles, Human chromosome 6 gene stubs). ... Interleukin 20 receptor, alpha subunit, is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the ... The interleukin 20 receptor, alpha subunit is also referred to as IL20R1 or IL20RA. The IL20RA receptor is involved in both pro ...
In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both ... "Entrez Gene: TRG@ T cell receptor gamma locus". Lefranc MP, Rabbitts TH (Aug 1989). "The human T-cell receptor γ (TRG) genes". ... molecules at the surface of antigen presenting cells (APC) (APC). Each T cell receptor is a dimer consisting of one alpha and ... the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor ...
"A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR". Cell. 66 ... "Entrez Gene: RXRA retinoid X receptor, alpha". "Retinoic acid receptor RXR-alpha - Homo sapiens (Human)". UniProt. Na SY, Choi ... Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear ... receptor that in humans is encoded by the RXRA gene. Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are ...
1999). "Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes". Immunity. 10 (4): 473- ... v t e (Genes on human chromosome 2, All stub articles, Human chromosome 2 gene stubs). ... "Acidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, ... "Entrez Gene: SAG S-antigen; retina and pineal gland (arrestin)". Ghalayini AJ, Anderson RE (1992). "Activation of bovine rod ...
1992). "Mutations in T-cell antigen receptor genes alpha and ß block thymocyte development at different stages". Nature. 360 ( ... Thomas, K. R.; Capecchi, M. R. (1987). "Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells". Cell. ... and that his lab was trying to set up gene targeting to study the immunology T-cell receptors they had cloned. So, he wrote to ... Cell. 135 (3): 549-560. doi:10.1016/j.cell.2008.09.060. PMC 2673196. PMID 18984165. Lee, Y-S; Silva, AJ (Feb 2009). "The ...
"Entrez Gene: FCGRT Fc fragment of IgG, receptor, transporter, alpha". Simister NE, Mostov KE (1989). "Cloning and expression of ... Rodewald R, Kraehenbuhl JP (July 1984). "Receptor-mediated transport of IgG". The Journal of Cell Biology. 99 (1 Pt 2): 159s- ... The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is ... Genes on human chromosome 19, Human gene pages with Wikidata item, Fc receptors). ...
... receptor cooperates with high-density lipoprotein receptor in recognition of apoptotic cells by thymic nurse cells". Journal of ... This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins belong to the alpha-ketoglutarate- ... Zakharova L, Dadsetan S, Fomina AF (October 2009). "Endogenous Jmjd6 gene product is expressed at the cell surface and ... This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells. ...
... regulates T-cell receptor alpha enhancer function [corrected]". Genes & Development. 5 (5): 880-894. doi:10.1101/gad.5.5.880. ... "A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer". Genes & Development. ... It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. ... Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It's a member of T cell ...
Sareneva T, Julkunen I, Matikainen S (2000). "IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells ... is a human gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein ... "Entrez Gene: IL18RAP interleukin 18 receptor accessory protein". Born TL, Thomassen E, Bird TA, Sims JE (November 1998). " ... 2000). "IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18". J. ...
PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor ... "Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. ... Cell Genet. 52 (3-4): 147-50. doi:10.1159/000132865. PMID 2630187. Bout A, Franse MM, Collins J, Blonden L, Tager JM, Benne R ( ... This gene encodes an enzyme operative in the beta oxidation system of the peroxisomes. Deficiency of this enzyme leads to ...
There are two forms of the PDGF-R, alpha and beta each encoded by a different gene. Depending on which growth factor is bound, ... Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet- ... The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon ... Genes on human chromosome 4, Genes on human chromosome 5, Growth factors, Signal transduction, Tyrosine kinase receptors). ...
Mohan, S; Paul, SF; Shroff, S; Venkatesan, V (2009). "Interleukin-4-receptor alpha gene polymorphism and the risk of renal cell ... "GGN repeat length and GGN/CAG haplotype variations in the androgen receptor gene and prostate cancer risk in south Indian men ... "South Indian men with reduced CAG repeat length in the androgen receptor gene have an increased risk of prostate cancer". ... Vijayalakshmi, K; Vettriselvi, V; Krishnan, M; Shroff, S; Jayanth, VR; Paul, SF (2005). "Cytochrome p4501A1 gene variants as ...
"A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell ... including generating the mutant allele of retinoic acid receptor genes and studying the expression of receptor genes, Hox genes ... P19 cells provide valuable formation of both neuronal cells and muscle cells in vitro. Since P19 cells are easy to maintain and ... These stem cells were named embryonal carcinoma P19 cells. These derived P19 cells grew rapidly without feeder cells and were ...
... a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene". The EMBO Journal. ... is integral to the expression of estrogen receptor alpha, and (in estrogen receptor negative/androgen receptor positive cancers ... mouse gene equivalent to GATA3) is critical for the embryonic development and/or function of various cell types (e.g. fat cells ... "The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells". Cell. 89 (4): 587 ...
Le Coniat M, Kinet JP, Berger R (1990). "The human genes for the alpha and gamma subunits of the mast cell receptor for ... 1988). "Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene ... "Entrez Gene: FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide". Gounni AS (2006). "The high-affinity ... 1988). "Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor". Nucleic Acids Res. 16 (8 ...
The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by ... August 2001). "Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice ... also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. This gene ... "The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization ...
... synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin". Science. 257 (5066): 50-56. Bibcode: ... Neurexin-2-alpha is a protein that in humans is encoded by the NRXN2 gene. Neurexins are a family of proteins that function in ... the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two ... NMDA receptor subunits, neurexins, and neuroligins". Mol. Cell. Neurosci. 11 (3): 161-172. doi:10.1006/mcne.1998.0679. PMID ...
... synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin". Science. 257 (5066): 50-56. Bibcode: ... Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. Neurexins are a family of proteins that function in ... the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two ... The gene is found in a single copy on the short arm of chromosome 2 (2p16.3). The gene is 1,112,187 bases in length, is located ...
... synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin". Science. 257 (5066): 50-6. Bibcode: ... Neurexin-3-alpha is a protein that in humans is encoded by the NRXN3 gene. Neurexins are a family of proteins that function in ... the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two ... NRXN1 and NRXN3, are among the largest known human genes. Three of the genes (NRXN1-3) utilize two alternate promoters and ...
"Restricted usage of T-cell receptor V alpha sequence and variable-joining pairs after normal T-cell development and bone marrow ... "Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cell. Signal. 13 (5): 345-52. doi: ... "Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product". Cell. Signal. 13 (5): 345-52. doi: ... Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the ...
... activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells". Mol ... DNA Cell Biol. 24 (7): 464-9. doi:10.1089/dna.2005.24.464. PMID 16008515. "Entrez Gene: RPAIN RPA interacting protein". Blonska ... Cell. Biol. 24 (24): 10757-65. doi:10.1128/MCB.24.24.10757-10765.2004. PMC 533972. PMID 15572679. Gerhard DS, Wagner L, ... RPA-interacting protein is a protein that in humans is encoded by the RPAIN gene. GRCh38: Ensembl release 89: ENSG00000129197 ...