"The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762-72. doi:10.1172/JCI17491. PMC ... member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes. 53 (9): 2483-6. doi:10.2337/diabetes.53.9.2483 ... "Entrez Gene: SLC6A14 solute carrier family 6 (amino acid transporter), member 14". Ohman M, Oksanen L, Kaprio J, Koskenvuo M, ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome X, Solute carrier family ...

Gene-environment interactions and obesity--further aspects of genomewide association studies. Nutrition, 25(10), 998-1003. ... Processes classified as examples of gene-environment interplay include gene-environment interaction, gene-environment ... Gene-environment interplay has been found to play a part in the majority of diseases. For instance, gene-environment ... Gene-environment interplay, also known as nature-nurture interplay, is a term encompassing multiple ways that genes and ...

Heber D, Carpenter CL (19 April 2011). "Addictive Genes and the Relationship to Obesity and Inflammation". Molecular ... "Dopamine Genes (DRD2/ANKK1-TaqA1 and DRD4-7R) and Executive Function: Their Interaction with Obesity". PLOS ONE. 7 (7): e41482 ... It is now known to be located in the coding region of the ANKK1 gene which controls the synthesis of dopamine in the brain. The ... This gene contains a single nucleotide polymorphism that causes an amino acid substitution within the 11th of 12 ankyrin ...

Apart from being as a general tumor suppressor gene, p53 also plays an important part in regulating of metabolism. p53 ... Khandekar MJ, Cohen P, Spiegelman BM (November 2011). "Molecular mechanisms of cancer development in obesity". Nature Reviews. ... It provides resistance to oxidative stress that would regulates a set of genes that increase glucose metabolism and reduce ... Recent research has revealed that metabolic reprogramming occurs as a consequence of mutations in cancer genes and alterations ...

... gene: positive association of the T228A polymorphism with obesity and type 2 diabetes". Human Molecular Genetics. 10 (17): 1753 ... gene: positive association of the T228A polymorphism with obesity and type 2 diabetes". Human Molecular Genetics. 10 (17): 1753 ... "Entrez Gene: SORBS1 sorbin and SH3 domain containing 1". Lin WH, Huang CJ, Liu MW, Chang HM, Chen YJ, Tai TY, Chuang LM (May ... A single nucleotide polymorphism in SORBS1 was found to be associated with type 2 diabetes and obesity. SORBS1 has been shown ...

Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge". The Hungry Gene: The Inside Story of the Obesity Industry. ... Shell E (January 1, 2002). "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the Obesity Industry. Atlantic Monthly ...

Shell E (January 1, 2002). "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the Obesity Industry. Atlantic Monthly ... and cloning of the leptin and leptin receptor genes, has had a major role in the area of understanding human obesity. Cyrus ... cite web}}: Missing or empty ,title= (help) Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge". The Hungry Gene: The ... Inside Story of the Obesity Industry. Atlantic Monthly Press. ISBN 978-1422352434. ...

Defects in the leptin gene are associated with severe obesity in animals and in humans. Leptin acts on sets of neurons in brain ... Friedman's work in the area of obesity and the leptin gene has led to Friedman receiving many prestigious awards: 1994 and 1996 ... Ruppel Shell, Ellen (2002). The Hungry Gene: The Inside Story of the Obesity Industry. Grove Press. ISBN 0-8021-4033-5. ... Giridharan, N V (1998). "Animal models of obesity & their usefulness in molecular approach to obesity". Indian J Med Res. 108: ...

2009). "Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with ... 2009). "Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study". Obesity (Silver ... Variants of the GNPDA2 gene may be associated with obesity. GRCh38: Ensembl release 89: ENSG00000163281 - Ensembl, May 2017 ... 2009). "Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population ...

Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge". The Hungry Gene: The Inside Story of the Obesity Industry. ... Shell E (January 1, 2002). "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the Obesity Industry. Atlantic Monthly ...

"Omentin plasma levels and gene expression are decreased in obesity". Diabetes. 56 (6): 1655-61. doi:10.2337/db06-1506. PMID ... "Entrez Gene: ITLN1 intelectin 1 (galactofuranose binding)". Suzuki YA, Shin K, Lönnerdal B (December 2001). "Molecular cloning ... Intelectin-1, also known as omentin or intestinal lactoferrin receptor, is an intelectin encoded in humans by the ITLN1 gene. ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, All stub articles, ...

... at genes that are linked to both obesity and type 2 diabetes, if the 'thrifty gene' hypothesis is correct. Two comprehensive ... "Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the 'drifty gene' hypothesis". Int J ... but the idea was soon expanded to encompass obesity as well. Thrifty genes are genes which enable individuals to efficiently ... The drifty gene hypothesis was presented as part of a presidential debate at the 2007 Obesity Society meeting in New Orleans, ...

October 2009). "Obesity genes identified in genome-wide association studies are associated with adiposity measures and ... Variants of the MTCH2 gene may be associated with obesity. MTCH2 represses mitochondrial metabolism such that a deficiency of ... June 2010). "Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study". Obesity. 18 ... Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene. MTCH2 resides on ...

"How Helpful Would A Genetic Test For Obesity Risk Be?". NPR. 6 May 2019. Retrieved 11 May 2019. "Ministerraad stemt in met ... Resnick, Brian (24 August 2018). "Heart disease risk is hidden in your genes. Scientists are getting better at finding it". Vox ... Fleming, Nic (29 January 2014). "Can we ever fully trust personal gene tests?". BBC News. Retrieved 11 May 2019. ...

Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge" and "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the ... Obesity Industry. Atlantic Monthly Press. ISBN 978-1422352434. Casadevall, Arturo; Pirofski, Liise-anne (October 2003). "The ... Rudolph Leibel (Class of 1967), discoverer of the hormone leptin and cloning of the leptin and leptin receptor genes. Noah ...

These include minimally invasive surgeries to treat cancer and obesity; microsurgeries to restore voice, hearing, and facial ... which allow real-time imaging of tumors and gene therapies during surgery to ensure complete treatment, as well as the nation's ... function; MRI-guided gene therapy for brain cancer; heated intraperitoneal chemotherapy for abdominal cancer; spine and joint ...

Beale EG, Hammer RE, Antoine B, Forest C (2004). "Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene ... "Entrez Gene: PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)". Pilz AJ, Willer E, Povey S, Abbott CM (October 1992). "The ... Phosphoenolpyruvate carboxykinase 1 (soluble), also known as PCK1, is an enzyme which in humans is encoded by the PCK1 gene. ... The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of ...

Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge". The Hungry Gene: The Inside Story of the Obesity Industry. ... Shell E (January 1, 2002). "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the Obesity Industry. Atlantic Monthly ... and cloned the leptin and leptin receptor genes, which have had a major role in the area of understanding human obesity. Mark ...

2009). "Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with ... 2009). "Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study". Obesity (Silver ... Variants of the KCTD15 gene may be associated with obesity. Potassium channel tetramerisation domain GRCh38: Ensembl release 89 ... 2009). "Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population ...

Variants in the PCSK1 gene may be associated with obesity. Proprotein convertase subtilisin/kexin type 1 inhibitor GRCh38: ... Portal: Biology (Genes on human chromosome 5, All articles with unsourced statements, Articles with unsourced statements from ... Seidah NG, Mattei MG, Gaspar L, Benjannet S, Mbikay M, Chrétien M (September 1991). "Chromosomal assignments of the genes for ... April 2009). "Replication and extension of genome-wide association study results for obesity in 4923 adults from northern ...

Shell E (January 1, 2002). "Chapter 4: On the Cutting Edge". The Hungry Gene: The Inside Story of the Obesity Industry. ... Shell E (January 1, 2002). "Chapter 5: Hunger". The Hungry Gene: The Inside Story of the Obesity Industry. Atlantic Monthly ... and cloning of the leptin and leptin receptor genes, has had a major role in the area of understanding human obesity. Jean C. ...

Human as well murine STAT4 genes lie next to STAT1 gene locus suggesting that the genes arose by gene duplication. STAT ... Obesity & Metabolism. 15 Suppl 3 (s3): 71-81. doi:10.1111/dom.12162. PMID 24003923. S2CID 22297620. Korman BD, Kastner DL, ... Genes on human chromosome 2, Gene expression, Immune system, Proteins, Transcription factors, Signal transduction). ... STAT proteins are key activators of gene transcription which bind to DNA in response to cytokine gradient. STAT proteins are a ...

However, soon thereafter J. F. Caro's laboratory could not detect any mutations in the leptin gene in humans with obesity. On ... There are different types of obesity depending on where fat cells are stored. Abdominal obesity, excess fat cell accumulation ... "Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity". The Journal of Clinical ... mutations in the leptin gene resulted in the obese phenotype opening the possibility of leptin therapy for human obesity. ...

May 2002). "Increased resistin gene and protein expression in human abdominal adipose tissue". The Journal of Clinical ... Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of ... While central obesity can be obvious just by looking at the naked body (see the picture), the severity of central obesity is ... Central obesity in individuals with normal BMI is referred to as normal weight obesity. There are sex-dependent differences in ...

Obesity. 16 (7): 1481-1486. doi:10.1038/oby.2008.206. PMID 18421280. S2CID 40979522. "Entrez Gene: C1QTNF3 C1q and tumor ... Complement C1q tumor necrosis factor-related protein 3 is a protein that in humans is encoded by the C1QTNF3 gene. GRCh38: ... Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S (Feb 2001). "Molecular cloning and characterization of a novel gene, CORS26, ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 5, All stub articles, ...

"Role of Jhdm2a in regulating metabolic gene expression and obesity resistance". Nature. 458 (7239): 757-761. Bibcode:2009Natur. ... Inoue, Azusa; Jiang, Lan; Lu, Falong; Zhang, Yi (1 October 2017). "Genomic imprinting of Xist by maternal H3K27me3". Genes & ... Genes & Development. 32 (23-24): 1525-1536. doi:10.1101/gad.318675.118. ISSN 1549-5477. PMC 6295166. PMID 30463900. Matoba, ... "Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming". Nature Cell ...

Volkow, Nora D.; Wang, Gene-Jack; Baler, Ruben D. (2011-01-01). "Reward, dopamine and the control of food intake: implications ... Areas of interest include how olfaction contributes to flavor, food addiction and obesity, taste preferences, and the ... With neurogastronomy's roots in neuroscience and psychology, clinical translation into research in obesity, diabetes, ... for obesity". Trends in Cognitive Sciences. 15 (1): 37-46. doi:10.1016/j.tics.2010.11.001. ISSN 1364-6613. PMC 3124340. PMID ...

Ramsay's research has investigated single-gene disorders, epigenetics, obesity and hypertension. She was the President of the ... Her research interests include the molecular epidemiology of single-gene disorders, the epigenetics of fetal alcohol spectrum ... disorder studied using mouse models and understanding the genetic and environmental risk factors for obesity and related ...

A novel gene linked to obesity and hyperinsulinemia". Nature Genetics. 15 (3): 269-72. doi:10.1038/ng0397-269. PMID 9054939. ... He was able to obtain mice without the UCP2 gene, demonstrating the essential role of this gene in innate immunity and the ... He then analyzed the mechanisms of control of the tissue-specific transcription of the UCP gene. In addition, he studied the ... Applications of the work include metabolic diseases (obesity, diabetes), nutrition, degenerative diseases and autoimmune ...

Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene. The Prox1 gene is critical for the ... "Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity". Nature Genetics. 37 (10): 1072-1081 ... 2003). "Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies". Genes Chromosomes Cancer. 38 (1 ... Gene expression data for mouse, human and macaque from the Allen Brain Atlases can be found here. PROX1 is used as a marker for ...

PCK1 as candidate diabetes and obesity gene". Trends in Endocrinology and Metabolism. 15 (3): 129-35. doi:10.1016/j.tem.2004.02 ... Glucocorticoids induce gene transcription of PEPC-K in liver but repress the transcription in adipose tissues. Failure in ... Furthermore, gene expression of PEPC-K can be suppressed by norepinephrine, glucocorticoids, and insulin. Norepinephrine is a ... Increases in PEPC-K levels or overexpression of the gene that codes for PEPC-K will increase glyceroneogenesis. Also, ...

K. S. Jayaraman (2005). "'Sumo' rats set researchers on hunt for obesity genes". Nature Medicine. 11 (2): 108. doi:10.1038/ ... "Mice to reveal key to human obesity". The Times of India. Archived from the original on 16 June 2013. "Australia-India food ... The institute majorly conducts research in obesity, diabetes, food chemistry, dietetics, clinical toxicology, and micronutrient ... to serve as pre-clinical animal models in drug development for chronic diseases like Obesity and Diabetes. Established a state ...

The GSTK1 gene consists of eight exons and seven introns and although it is a member of the GST family, its structure has been ... The amount of expression of adiponectin has been observed to be related to diseases such as insulin resistance, obesity, and ... Gao F, Fang Q, Zhang R, Lu J, Lu H, Wang C, Ma X, Xu J, Jia W, Xiang K (2009). "Polymorphism of DsbA-L gene associates with ... Also, the GSTK1 gene is unregulated when it is inflicted with oxidative stress and are over expressed in many tumors leading to ...

Polymorphisms in various genes controlling appetite and metabolism predispose individuals to obesity when sufficient calories ... International Journal of Pediatric Obesity Task Force on Childhood Obesity Classification of childhood obesity Obesity and the ... Childhood obesity - CNN "Childhood Obesity". Archived from the original on 2015-09-24. Retrieved 2006-09-14. Childhood obesity ... "Management and prevention of obesity and its complications in children and adolescents , Obesity Hub". obesity hub. Archived ...

It usually does not cause symptoms but people with prediabetes often have obesity (especially abdominal or visceral obesity), ... Dietrich S, Jacobs S, Zheng JS, Meidtner K, Schwingshackl L, Schulze MB (November 2019). "Gene-lifestyle interaction on risk of ... July 2021). "Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England: a population-based cohort ... Overweight or obesity (body mass index > 25 kg/m2) History of gestational diabetes or infant born with birth weight greater ...

It has been found LACTB could cause obesity through gene co-expression analysis based on data integrated from multiple sources ... Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene. This gene ... "Entrez Gene: LACTB lactamase, beta". Peitsaro N, Polianskyte Z, Tuimala J, Pörn-Ares I, Liobikas J, Speer O, Lindholm D, ... The LACTB gene is located at chromosome 15q22.1, consisting of 8 exons. Alternative splicing results in multiple transcript ...