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*  Lethal allele
... s may be recessive, dominant, or conditional depending on the gene or genes involved. Lethal alleles can cause ... Lethal alleles (also referred to as lethal genes or lethals) are alleles that cause the death of the organism that carries them ... Terminator gene Gluecksohn-Waelsch, Salome (1963). "Lethal Genes and Analysis of Differentiation". Science. 142 (3597): 1269-76 ... ISBN 978-0-07-094669-9. Lobo, I (2008). "Mendelian Ratios and Lethal Genes". Nature Education. 1 (1): 138. Ratjen, Felix; ...
*  Point accepted mutation
CS1 maint: Multiple names: authors list (link) Lobo, Ingrid (2008). "Mendelian Ratios and Lethal Genes". Nature. Nature ... If a point mutation occurs within an expressed region of a gene, an exon, then this will change the codon specifying a ... In particular, silent mutations are not point accepted mutations, nor are mutations which are lethal or which are rejected by ... "From Gene to Protein". Biology: Australian Version (8th ed.). Pearson Education Australia. pp. 327-350. ISBN 9781442502215. CS1 ...
*  BLOSUM
Lobo, Ingrid (2008). "Mendelian Ratios and Lethal Genes". Nature. Nature Publishing Group. Retrieved 19 October 2013. ... BLOSUM scores was used to predict and understand the surface gene variants among hepatitis B virus carriers and T-cell epitopes ... Campbell NA; Reece JB; Meyers N; Urry LA; Cain ML; Wasserman SA; Minorsky PV; Jackson RB (2009). "From Gene to Protein". ... Roque-Afonso AM, Ferey MP, Ly TD (2007). "Viral and clinical factors associated with surface gene variants among hepatitis B ...
*  Oxitec
... h Cookson, Clive (23 April 2015). "'Lethal gene' to combat malaria relies on laws of attraction". Financial Times. ...
*  Francis Collins
Pines, Maya (2008). "Stalking a Lethal Gene:Discovering the Gene for Cystic Fibrosis". Howard Hughes Medical Institute. ... The gene was identified in June 1989, and the results were published in the journal Science on September 8, 1989. This ... Before joining NHGRI, he earned a reputation as a gene hunter at the University of Michigan. He has been elected to the ... His gene-hunting approach, which he named "positional cloning", developed into a powerful component of modern molecular ...
*  Jan Klein
... and frequent presence of homozygous lethal genes. Klein group's combined t and H2 studies on wild mice from all over the world ... The two genes are thus unrelated to each other and to the class I and class II genes, but they are accidentally hooked together ... They also contributed evidence for the omnipresence of Mhc genes in jawed vertebrates by identifying such genes in a wide range ... not even the class I and class II genes were in a single cluster and the class III genes were scattered all over the genome. ...
*  Erwin Baur
In 1908 Baur demonstrated a lethal gene in the Antirrhinum plant. In 1909 working on the chloroplast genes in Pelargonium ( ... "Human biodiversity: genes, race, and history", Jonathan M. Marks. Transaction Publishers, 1995. p. 88. ISBN 0-202-02033-9, ISBN ...
*  Matthiola incana
In these varieties, the singleness allele is closely linked to a pollen-lethal gene. Thus the pollen (male) contribution to ... The double-flowered form is caused by a recessive gene variant (allele) in the homozygous condition. Therefore, according to ...
*  Axolotl
... and Its Autonomous Cell-Lethal Genes". American Zoologist. Oxford University Press. 18: 195-206. doi:10.1093/icb/18.2.195. Matt ... The genes responsible for neoteny in laboratory animals may have been identified; however, they are not linked in wild ... Axolotls are used in heart defect studies due to the presence of a mutant gene that causes heart failure in embryos. Since the ... Identification of Genes Involved in Limb Regeneration in the Axolotl Ambystoma mexicanum Nowoshilow, Sergej; Schloissnig, ...
*  SNAP25
Homozygous deletions of the SNAP-25 gene are lethal. Subsequent studies have suggested that at least some of the SNAP-25 gene ... Synaptosomal-associated protein 25 (SNAP-25) is a t-SNARE protein that is encoded by the SNAP25 gene in humans. SNAP-25 is a ... Zhao N, Hashida H, Takahashi N, Sakaki Y (1994). "Cloning and sequence analysis of the human SNAP25 cDNA". Gene. 145 (2): 313-4 ... Consistent with the regulation of synaptic Ca2+ responsiveness, heterozygous deletion of the SNAP-25 gene in mice results in a ...
*  Aedes aegypti
Clive Cookson (23 April 2015). "'Lethal' gene to combat malaria relies on laws of attraction". Financial Times. Retrieved 2015- ... The genes like ECFP (enhanced cyan fluorescent protein), Nix (male-determining factor gene), Aaeg-wtrw (Ae. aegypti water witch ... To produce more OX513A mosquitoes for control projects, the self-limiting gene is switched off (using the Tet-Off system) in ... Their offspring inherit the self-limiting gene and die before reaching adulthood-before they can reproduce or spread disease. ...
*  Cloning vector
"A plasmid vector with positive selection and directional cloning based on a conditionally lethal gene". Gene. 169 (1): 131-2. ... This may involve the use of a gene lethal to the host cells, such as barnase, Ccda, and the parD/parE toxins. This typically ... works by disrupting or removing the lethal gene during the cloning process, and unsuccessful clones where the lethal gene still ... Human artificial chromosome may be potentially useful as a gene transfer vectors for gene delivery into human cells, and a tool ...
*  Genetically modified insect
... this lethal gene is dominant so that all offspring of the RIDL insect will also inherit the lethal gene. This lethal gene has a ... a lethal gene in their genome (an organism's DNA). Lethal genes cause death in an organism, and RIDl genes only kill young ... The lethal gene is turned off when the RIDL insects are mass reared in an insectory, and turned on when they are released into ... The company Oxitec has developed GM-males which have a lethal gene that interrupts female development and kills them in a ...
*  L. C. Dunn
"Evidence of evolutionary forces leading to the spread of lethal genes in wild populations of house mice", Proc. Natl. Acad. Sci ... "Independent Genes in Mice", Genetics, v.5, pp. 344-361. Dunn, L.C. 1920. "Linkage in mice and rats", Genetics, v.5, pp. 325-343 ... His early work with the mouse T-locus and established ideas of gene interaction, fertility factors, and allelic distribution. ...
*  HIKESHI
The mouse homolog, lethal gene on chromosome 7 Rinchik 6 protein is encoded by the l7Rn6 gene. When the l7Rn6 protein is ... The homologous mouse L7rn6 gene encodes a protein called lethal gene on chromosome 7 Rinchik 6. 1 mfgclvagrl vqtaaqqvae ... Orthologs, or orthologous genes, are genes in different species that are similar to each other because they originated from a ... HIKESHI is a protein-coding gene in Homo sapiens. Alternate names for the gene are FLJ43020, HSPC138, HSPC179, and L7RN6. ...
*  Five prime untranslated region
In addition, this region has been involved in transcription regulation, such as the sex-lethal gene in Drosophila. Regulatory ... Gene. 423 (2): 108-15. doi:10.1016/j.gene.2008.07.013. PMID 18692553. Rogers, Jack T.; Bush, Ashley I.; Cho, Hyan-Hee; Smith, ... In humans, ~35% of all genes harbor introns within the 5′ UTR. As the 5′ UTR has a high GC content, secondary structures often ... An example is regulation of the msl2 gene. The protein SXL attaches to an intron segment located within the 5′UTR segment of ...
*  List of guinea pig breeds
... "lethal white gene" or simply "lethal gene", is an incomplete dominant. It is lethal when homozygous, resulting in full white ... They are caused by the same gene, and whether a cavy appears roan or Dalmatian is defined by modifier factors. Many cavies have ... However, there is growing evidence that the genes responsible for the satin coat also can cause severe bone problems, including ...
*  Non-Mendelian inheritance
To prevent lethal gene dosage problems, one of these chromosomes is inactivated following fertilization. This process occurs ... Gene conversion can be one of the major forms of non-Mendelian inheritance. Gene conversion arises during DNA repair via DNA ... The protein encoded by this gene helps to regulate body size. Mice that possess two functional copies of this gene are larger ... This is because the maternal Igf2 gene is imprinted. Imprinting results in the inactivation of the Igf2 gene on the chromosome ...
*  Life extension
... and the changes caused by these genes activating can be lethal. It is a statistical certainty that we possess more lethal genes ... In The Selfish Gene, Richard Dawkins describes an approach to life-extension that involves "fooling genes" into thinking the ... Rattan, S. I. S.; Singh, R. (2008-10-22). "Progress & Prospects: Gene therapy in aging". Gene Therapy. 16 (3-9): 3-9. doi: ... Therefore, to extend life, we should be able to prevent these genes from switching on, and we should be able to do so by " ...
*  MIMT1
Deletion of this gene is lethal in cattle, causing still births and abortions. It is lethal in 85% of individuals with the ... It is an imprinted gene, which is paternally expressed. ...
*  LLGL1
Lethal(2) giant larvae protein homolog 1 is a protein that in humans is encoded by the LLGL1 gene. This gene encodes a protein ... "Entrez Gene: LLGL1 lethal giant larvae homolog 1 (Drosophila)". Campbell HD, Fountain S, Young IG, et al. (1997). "Genomic ... 2002). "Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of ... The gene is located within the Smith-Magenis syndrome region on chromosome 17. ENSG00000131899 GRCh38: Ensembl release 89: ...
*  OSTM1
"Identification of a novel mutation in the coding region of the grey-lethal gene OSTM1 in human malignant infantile ... This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome ... Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. This is also known as ... The OSTM1 gene is regulated by the Microphthalmia-associated transcription factor. OSTM1 has been shown to interact with RGS19 ...
*  BioBrick
The destination plasmid contains the toxic(lethal) gene, to ease the selection of correctly assembled plasmid. The destination ... and it does not require the involved plasmids to have different antibiotic resistance genes. This method reduces noise from ... plasmid also have a different antibiotic resistance genes than the plasmids carrying the BioBrick parts. All three plasmids are ...
*  Pinus taeda
A lethal equivalent is the number of deleterious genes per haploid genome whose cumulative effect is the equivalent of one ... Most of the genes are duplicates. Some genes have the longest introns observed among 24 fully sequenced plant genomes. ... lethal gene. The presence of at least eight lethal equivalents implies substantial inbreeding depression upon self- ... The loblolly pine harbors an average load of at least eight lethal equivalents. ...
*  Osteochondroprogenitor cell
General Trsp gene deletion is lethal to the embryo. The results of this research was used as a model for Kashin-Beck disease. ... General gene knock out of the TGF-β resulted in death. Conditional inactivation of TGF-βr2 of osteochondroprogenitor cells in ... The disease has symptoms similar to those resulting from Trsp gene knockout. Loss of the regulator, Pten, of the ... Sox9 blocked osteochondroprogenitor cells were found to express osteoblast marker genes, reprogramming the cells into the ...