... the controlled gene expression during transcription and translation coupled with the rearrangements of immunoglobulin gene ... Vk gene segments can join with either one of the Jk functional gene segments. The overall rearrangements result in a gene ... During the development of B cells, the immunoglobulin gene undergoes sequences of rearrangements that lead to formation of the ... 1979). "Cloned pairs of variable region genes for immunoglobulin heavy-chains isolated from a clone library of the entire mouse ...
Genes and Immunity. 3 (3): 158-64. doi:10.1038/sj.gene.6363848. PMID 12070780. Novak N, Kraft S, Bieber T (December 2001). "IgE ... Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has been found only in mammals. IgE is ... Presence of a unique immunoglobulin as a carrier of reaginic activity". Journal of Immunology. 97 (1): 75-85. doi:10.4049/ ... November 2013). "A beneficial role for immunoglobulin E in host defense against honeybee venom". Immunity. 39 (5): 963-75. doi: ...
"Entrez Gene: PIGR polymeric immunoglobulin receptor". Kaetzel CS (August 2005). "The polymeric immunoglobulin receptor: ... Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is an Fc ... pIgR has a strong specificity to polymeric immunoglobulins and is not responsive to monomeric immunoglobulin. The ligand's J- ... "Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31----q41". Cytogenetics and Cell ...
"KIR2DL3 - Killer cell immunoglobulin-like receptor 2DL3 precursor - Homo sapiens (Human) - KIR2DL3 gene & protein". www.uniprot ... The KIR genes are polymorphic, which means that they have many different alleles. The KIR genes are also extremely homologous, ... KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3 is a transmembrane glycoprotein expressed by the natural killer cells ... The HLA-C molecules are human leukocyte antigens and are the gene complexes to encode major histocompatibility complex (MHC) ...
... is a protein that in humans is encoded by the IGSF3 gene. The protein encoded by this gene ... "Entrez Gene: Immunoglobulin superfamily member 3". Retrieved 2018-10-06. v t e This article incorporates text from the United ... is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, All stub articles, Human ...
Rabbitts, T. H. (1983). "The human immunoglobulin genes. The nineteenth Colworth medal lecture". Biochemical Society ... Melton, D. W. (1990). "The use of gene targeting to develop animal models for human genetic diseases". Biochemical Society ... Flavell, R. A. (1983). "The globin genes of rabbit and man. The eighteenth Colworth medal lecture". Biochemical Society ... Brownlee, G. G. (1979). "The Fourteenth Colworth Medal Lecture Sequencing eukaryotic genes or the anatomy of DNA". Biochemical ...
Papavasiliou, F.Nina; Schatz, David G (April 2002). "Somatic Hypermutation of Immunoglobulin Genes". Cell. 109 (2): S35-S44. ... "Control of immunoglobulin gene rearrangements in developing B cells". Current Opinion in Immunology. 9 (2): 233-238. doi: ... "Cell-cycle-regulated DNA double-strand breaks in somatic hypermutation of immunoglobulin genes". Nature. 408 (6809): 216-221. ... gene expression outcomes, and cellular function". Proceedings of the National Academy of Sciences of the United States of ...
Rogozin IB, Kolchanov NA (November 1992). "Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base ... The product of gene PD-1 ordinarily represses cytotoxic immune responses. Inhibition of this gene allows a greater immune ... found that passenger genes, with chromosomal proximity to tumor suppressor genes, are collaterally deleted in some cancers. ... Epigenetic repression of DDR genes occurs more frequently than gene mutation in many types of cancer (see Cancer epigenetics). ...
... immunoglobulin). In human genome, the IgH gene loci are on chromosome 14. A typical antibody is composed of two immunoglobulin ... There are five types of mammalian immunoglobulin heavy chain: γ, δ, α, μ and ε. They define classes of immunoglobulins: IgG, ... "Intraclass diversification of immunoglobulin heavy chain genes in the African lungfish". Immunogenetics. 66 (5): 335-51. doi: ... Immunoglobulin+Heavy+Chains at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Educational Resource for ...
... is a protein that in humans is encoded by the LILRP2 gene. ENSG00000273922 ... "Entrez Gene: Leukocyte immunoglobulin-like receptor pseudogene 2". Retrieved 2016-09-02. v t e (Articles with short description ... Short description matches Wikidata, Orphaned articles from December 2022, All orphaned articles, Genes on human chromosome 19, ... Pseudogenes, All stub articles, Human chromosome 19 gene stubs). ...
Immunoglobulin lambda joining 3 is a protein that in humans is encoded by the IGLJ3 gene. "Human PubMed Reference:". National ... "Entrez Gene: Immunoglobulin lambda joining 3". Paul E, Iliev AA, Livneh A, Diamond B (December 1992). "The anti-DNA-associated ... Combriato G, Klobeck HG (June 1991). "V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light ... v t e (Articles with short description, Short description matches Wikidata, Human genes, Genes, Human proteins, All stub ...
... transcriptional coactivator for nuclear hormone receptors gene NCOA2; f) Immunoglobulin heavy chain gene IGH; g) enzyme genes ... "IGH immunoglobulin heavy locus (human )". Entrez Gene. "TTL tubulin tyrosine ligase (human)". Entrez Gene. "CHIC2 cysteine rich ... Thus, the ETV6 gene reportedly forms translocation-induced fusion genes with: a) tyrosine kinase receptor gene FGFR3; b) non- ... The following table lists the more frequently occurring genes to which ETV6 fuses, the function of these genes, these genes' ...
Toda M, Hirama T, Takeshita S, Yamagishi H (June 1989). "Excision products of immunoglobulin gene rearrangements". Immunology ... and more specifically the amplification of oncogenes and drug-resistant genes. This also supports that the genes on eccDNA are ... Overall, eccDNA has been linked to cancer and drug resistance, aging, gene compensation, and for this reason it continues to be ... For example, eccDNA can be formed from exons of protein coding genes, like mucin and titin. Researchers have hypothesized that ...
Bentley DL, Rabbits TH (1981). "Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene ... "Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene ... Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes the constant domain of kappa-type light chains ... "Entrez Gene: IGKC immunoglobulin kappa constant". Brady RL, Edwards DJ, Hubbard RE, et al. (1992). "Crystal structure of a ...
CEAs are immunoglobulins. Within humans there are total of 11 PSG genes located on the 19th chromosome; there are 17 genes ... These genes belong to a specific gene family; they are a subgroup of the carcinoembryonic antigen (CEA) family of genes. ... The protein portion of the PSG varies depending on the gene coding for it. Several of the genes and proteins have been ... PSG is a member of the immunoglobulin (Ig) superfamily and contains four immunoglobulin domains. The complete isolation of ...
... is a protein that in humans is encoded by the VSIG4 gene. This gene encodes a v- ... "Entrez Gene: V-set and immunoglobulin domain containing 4". Retrieved 2016-06-13. Helmy KY, Katschke KJ, Gorgani NN, Kljavin NM ... Articles with short description, Short description matches Wikidata, Genes on human chromosome X, All stub articles, Human ... set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. ...
"LILRA5 Gene - Leukocyte Immunoglobulin Like Receptor A5". Gene Cards. Retrieved 2021-12-11. "LILRA5 leukocyte immunoglobulin ... is a protein that in humans is encoded by the LILRA5 gene. This gene is one of the leukocyte receptor genes that form a gene ... immunoglobulin-like transcript 7 (ILT-7), and leukocyte immunoglobulin-like receptor 9 (LIR-9) ... Leukocyte immunoglobulin-like receptor subfamily A member 5 (LILR-A5) also known as CD85 antigen-like family member F (CD85f), ...
Ig heavy chain V-III region VH26 is a protein that in humans is encoded by the IGHV@ gene. IGHV is the immunoglobulin heavy ... "Entrez Gene: IGHV@ immunoglobulin heavy variable group". Forconi F, Sozzi E, Cencini E, et al. (November 2009). "Hairy cell ... Matthyssens G, Rabbitts TH (1981). "Structure and multiplicity of genes for the human immunoglobulin heavy chain variable ... "CD5+ diffuse large B-cell lymphoma consists of germline cases and hypermutated cases in the immunoglobulin heavy chain gene ...
"Entrez Gene: IGHD immunoglobulin heavy constant delta". Shin SU, Wei CF, Amin AR, et al. (1992). "Structural and functional ... Lee CE, Jackson KJ, Sewell WA, Collins AM (2007). "Use of IGHJ and IGHD gene mutations in analysis of immunoglobulin sequences ... 2006). "Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire ... Ig delta chain C region is a protein that in humans is encoded by the IGHD gene. GRCh38: Ensembl release 89: ENSG00000211898 - ...
"The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes". The ... "Entrez Gene: IGHE immunoglobulin heavy constant epsilon". Venkitaraman AR, Williams GT, Dariavach P, Neuberger MS (Aug 1991). " ... Max EE, Battey J, Ney R, Kirsch IR, Leder P (Jun 1982). "Duplication and deletion in the human immunoglobulin epsilon genes". ... Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". DNA. 1 (1): 11-8. doi: ...
Lectin 11 (SIGLEC11), a human immunoglobulin that binds to sialic acid, can be considered an example of such a gene conversion ... which have resulted from previous gene duplications. Gene conversion occurring between paralogous sequences (ectopic gene ... Biased gene conversion (BGC) occurs when one allele has a higher probability of being the donor than the other in a gene ... GC-biased gene conversion (gBGC) is the process by which the GC content of DNA increases due to gene conversion during ...
Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene. IGSF8 has also been designated as ... "Entrez Gene: IGSF8 immunoglobulin superfamily, member 8". Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and ... 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome ... 2003). "Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes". Br. J. Dermatol. 148 ...
Wang X, Stollar BD (1999). "Immunoglobulin VH gene expression in human aging". Clin. Immunol. 93 (2): 132-42. doi:10.1006/clim. ... E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene. This gene encodes a cytoplasmic ... 1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2 ... Genes on human chromosome 7, RING finger proteins, All stub articles, Human chromosome 7 gene stubs). ...
"NCBI Gene: RBPJ recombination signal binding protein for immunoglobulin kappa J region". "HGNC: RBPJ Symbol Report". Hsieh JJ, ... Recombination signal binding protein for immunoglobulin kappa J region is a protein that in humans is encoded by the RBPJ gene ... Oka C, Kawaichi M (1995). "V(D)J recombination of immunoglobulin genes". Advances in Biophysics. 31: 163-180. doi:10.1016/0065- ... 1990). "A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the ...
Wang X, Stollar BD (1999). "Immunoglobulin VH gene expression in human aging". Clin. Immunol. 93 (2): 132-42. doi:10.1006/clim. ... "Entrez Gene: EPC1 enhancer of polycomb homolog 1 (Drosophila)". Doyon Y, Côté J (2004). "The highly conserved and ... Enhancer of polycomb homolog 1 is a protein that in humans is encoded by the EPC1 gene. GRCh38: Ensembl release 89: ... 2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome ...
The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin ... Immunoglobulin lambda like polypeptide 5 is a protein that in humans is encoded by the IGLL5 gene. This gene encodes one of the ... "Entrez Gene: Immunoglobulin lambda like polypeptide 5". Retrieved 2017-10-23. This article incorporates text from the United ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 22, Wikipedia articles ...
"Immunoglobulin gene expression in transformed lymphoid cells". Proc. Natl. Acad. Sci. U.S.A. 80 (3): 825-9. Bibcode:1983PNAS... ...
Wang X, Stollar BD (November 1999). "Immunoglobulin VH gene expression in human aging". Clinical Immunology. 93 (2): 132-42. ... The deletion of this gene has been reported associated with Wilms tumor. GWAS show that genetic variations of the CPVL gene are ... Probable serine carboxypeptidase CPVL is an enzyme that in humans is encoded by the CPVL gene. The "CPVL" gene is expressed ... "Entrez Gene: CPVL carboxypeptidase, vitellogenic-like". Harris J, Schwinn N, Mahoney JA, Lin HH, Shaw M, Howard CJ, da Silva RP ...
Wang X, Stollar BD (November 1999). "Immunoglobulin VH gene expression in human aging". Clinical Immunology. 93 (2): 132-42. ... "Entrez Gene: SKAP2 src kinase associated phosphoprotein 2". Alenghat FJ, Baca QJ, Rubin NT, Pao LI, Matozaki T, Lowell CA, ... Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 7, All stub articles, ...
"Entrez Gene: IGSF2 immunoglobulin superfamily, member 2". Rivas A, Ruegg CL, Zeitung J, et al. (1995). "V7, a novel leukocyte ... Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene. Cluster of ... 2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res ... Molecular cloning and characterization of the V7 gene". J. Immunol. 154 (9): 4434-43. PMID 7722300. Soares LR, Rivas A, ...