"Entrez Gene: FIGF c-fos induced growth factor (vascular endothelial growth factor D)". Stacker SA, Caesar C, Baldwin ME, ... Orlandini M, Marconcini L, Ferruzzi R, Oliviero S (Oct 1996). "Identification of a c-fos-induced gene that is related to the ... gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes". Genomics. 47 (2): 207-16. doi:10.1006/ ... is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a ...
Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene. The Fos gene family consists of 4 ... "Entrez Gene: FOSL2 FOS-like antigen 2". Matsui M, Tokuhara M, Konuma Y, Nomura N, Ishizaki R (March 1990). "Isolation of human ... Molven A, Houge G, Berger R (November 1996). "Chromosomal assignment of the human gene encoding the Fos-related antigen-2 (FRA2 ... members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN ...
Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene. The Fos gene family consists of 4 ... "Entrez Gene: FOSL1 FOS-like antigen 1". Pognonec P, Boulukos KE, Aperlo C, Fujimoto M, Ariga H, Nomoto A, Kato H (May 1997). " ... Sinke RJ, Tanigami A, Nakamura Y, Geurts van Kessel A (Oct 1993). "Reverse mapping of the gene encoding the human fos-related ... Matsui M, Tokuhara M, Konuma Y, Nomura N, Ishizaki R (Mar 1990). "Isolation of human fos-related genes and their expression ...
The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Hitchcock LN, Lattal ... as indexed by the induced expression of c-Fos, an immediate early gene. Furthermore, inhibition of one hotspot results in the ... the induction of CDK5 gene expression occurs together with suppression of the G9A gene coding for dimethyltransferase acting on ...
"Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos". Genes Dev. 27 (18): 1959-73. doi:10.1101/gad.223339.113. ... gene duplications within the region of the S100 gene cluster on human chromosome 1q21". J. Mol. Evol. 56 (4): 397-406. Bibcode: ... "Entrez Gene: S100 calcium binding protein A7A". Wolf R, Mirmohammadsadegh A, Walz M, Lysa B, Tartler U, Remus R, Hengge U, ... "Entrez Gene: S100a7a S100 calcium binding protein". Briso EM, Guinea-Viniegra J, Bakiri L, Rogon Z, Petzelbauer P, Eils R, Wolf ...
Whilst studying in the Zürich laboratory, Hafezi identified the first known gene, c-Fos, that the absence of which could ... Fra1 can function in lieu of c-Fos to promote light-induced retinal photoreceptor death - work that was published in Genes & ... c-Fos and Fra1 are both components of the transcription factor AP-1, and in the year 2000, Hafezi and his colleagues presented ... Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A, Reme CE (1997). "The absence of c-fos prevents light- ...
"Entrez Gene: USF2 upstream transcription factor 2, c-fos interacting". Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, ... Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene. This gene encodes a member of the basic ... USF2 has been shown to interact with USF1 (human gene), PPRC1 and BRCA1. The USF2 gene is repressed by the microRNA miR-10a. ... flanking gene contributes to basal transcriptional gene activation". Biochemical Pharmacology. 65 (7): 1087-96. doi:10.1016/ ...
Genes include ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, ATF7, ATFx. van Dam H, Castellazzi M (2001). "Distinct roles of Jun : Fos and ... whereas it turned out later that some of them might be more similar to AP-1-like factors such as c-Jun or c-Fos. In general, ... Gene. 273 (1): 1-11. doi:10.1016/S0378-1119(01)00551-0. ISSN 0378-1119. PMID 11483355. Green, M. R.; Persengiev, S. P. (2003-06 ...
2000). "UV-Induced stabilization of c-fos and other short-lived mRNAs". Mol. Cell. Biol. 20 (10): 3616-25. doi:10.1128/MCB. ... DNA/RNA-binding protein KIN17 is a protein that in humans is encoded by the KIN gene. The protein encoded by this gene is a ... "Entrez Gene: KIN KIN, antigenic determinant of recA protein homolog (mouse)". Biard DS, Saintigny Y, Maratrat M, et al. (1997 ... 2003). "Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication". Proc. Natl. ...
... gene. The FOS gene family consists of four members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins ... The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ, Barrot M ...
... required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos ... X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located ... "Entrez Gene: XBP1 X-box binding protein 1". Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, ... The expression of this protein is required for the transcription of a subset of class II major histocompatibility genes. ...
The TET2 protein lacks a CXXC domain, but the IDAX gene, that's a neighbor of the TET2 gene, encodes a CXXC4 protein. IDAX is ... Focus on c-Fos, Egr1 and Arc". Front Behav Neurosci. 12: 79. doi:10.3389/fnbeh.2018.00079. PMC 5932360. PMID 29755331. ... This included more than 2,000 differentially methylated genes at 24 hours after training, with over 500 genes being ... preferring gene bodies of highly expressed genes and enhancers. The three mammalian DNA methyltransferases (DNMTs) show a ...
Ubeda M, Vallejo M, Habener JF (November 1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 ... Ubeda M, Vallejo M, Habener JF (November 1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 ... As a transcription factor, CHOP can regulate the expression of many anti-apoptotic and pro-apoptotic genes, including genes ... November 1992). "Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)". Genes, ...
Feng, J.L., and Villeponteau, B. (1990). Serum stimulation of the c-fos enhancer induces reversible changes in c-fos chromatin ... Heterchromatin is a repressor of gene expression and its loss leads to inappropriate gene expression with senescence. The model ... Irving, J., Feng, J., Wistrom, C., Pikaart, M., and Villeponteau, B. (1992). An altered repertoire of fos/jun (AP-1) at the ... Villeponteau, B., Landes, G.M., Pankratz, M.J., and Martinson, H.G. (1982). The chicken beta globin gene region. Delineation of ...
November 2000). "Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene". Genome ... Rothofsky ML, Lin SL (August 1997). "CROC-1 encodes a protein which mediates transcriptional activation of the human FOS ... November 2000). "Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene". Genome ... "Entrez Gene: Kua-UEV ubiquitin-conjugating enzyme E2 variant 1". Thomson TM, Lozano JJ, Loukili N, Carrió R, Serras F, Cormand ...
Kornhauser, J.M.; Nelson, D.E.; Mayo, K.E.; Takahashi, J.S. (1990). "Photic and circadian regulation of c-fos gene expression ... "Gene Discovered in Mice that Regulates Biological Clock". Chicago Tribune. April 29, 1994. "Found in Mouse: The Gene of a Night ... This revealed that the gene is closely related to the gene doubletime (dbt) in Drosophila, and casein kinase 1 epsilon (CKIe) ... Such a discovery influenced them to pursue exploration of the clock gene's role in appetite and energy. In Clock mutant mice, ...
The earliest identified and best characterized IEGs include c-fos, c-myc and c-jun, genes that were found to be homologous to ... Immediate early genes (IEGs) are genes which are activated transiently and rapidly in response to a wide variety of cellular ... Silencing of IE gene expression through antisense oligonucleotides, RNA interference, and gene-targeting ribosomes have been ... IEGs are distinct from "late response" genes, which can only be activated later, following the synthesis of early response gene ...
March 1998). "Tec and Jak2 kinases cooperate to mediate cytokine-driven activation of c-fos transcription". Blood. 91 (5): 1496 ... making it likely these two kinase genes arose through the process of gene-duplication. Tec family kinases are involved in the ... "Entrez Gene: TEC tec protein tyrosine kinase". Schmidt U, Boucheron N, Unger B, Ellmeier W (May 2004). "The role of Tec family ... TEC (gene) has been shown to interact with: ARHGEF12, CD117, DOK1, GNA12, Janus kinase 2, and Suppressor of cytokine signaling ...
The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto- ... Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion ... Gene. 195 (2): 141-9. doi:10.1016/S0378-1119(97)00097-8. PMID 9305758. "Entrez Gene: UBE2V1 ubiquitin-conjugating enzyme E2 ... "Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene". Genome Res. 10 (11): ...
Ubeda M, Vallejo M, Habener JF (November 1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 ... Ubeda M, Vallejo M, Habener JF (1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex ... Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene ... "Entrez Gene: JUND jun D proto-oncogene". Hyman SE, Malenka RC, Nestler EJ (2006). "Neural mechanisms of addiction: the role of ...
It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the JUN gene. c-jun was ... Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, ... Ubeda M, Vallejo M, Habener JF (November 1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 ... which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped ...
The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ (December ... Recent evidence has shown that ΔFosB also represses the c-fos gene that helps create the molecular switch-from the induction of ...
The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ (December ... Recent evidence has shown that ΔFosB also represses the c-fos gene that helps create the molecular switch-from the induction of ...
The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... Reduced gene expressions were associated with methylations of those genes and hypomethylation was found for genes involved in ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ (December ...
... genes, activating those genes in the nucleus accumbens (NAc). c-fos is well known to be important in addiction. The ccr2 gene ... The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ (December ...
The net result is gene activation and increased CDK5 expression. ... In contrast, ΔFosB binds to the c-fos gene and recruits ... to acetylate histones and facilitate gene activation. This is known to occur on many genes including fosB and c-fos in response ... The net result is c-fos gene repression. Figure 4: Epigenetic basis of drug regulation of gene expression Nestler EJ (December ... Recent evidence has shown that ΔFosB also represses the c-fos gene that helps create the molecular switch-from the induction of ...
In humans, the gene RUNX1 is 260 kilobases (kb) in length, and is located on chromosome 21 (21q22.12). The gene can be ... RUNX1 has been shown to interact with: C-Fos, C-jun, SUV39H1 TLE1, and VDR. Stat3 RUNX2 RUNX3 GRCh38: Ensembl release 89: ... to chromosomal translocation of the RUNX1 gene with the ETO / MTG8 / RUNX1T1 gene located on chromosome 8q22, t(8; 21), ... cloned the human RUNX1 gene; RUNX1 was found to be rearranged in the leukemic cell DNAs from t(8;21)(q22;q22) AML patients. ...
"Entrez Gene: JUNB jun B proto-oncogene". Hu YF, Li R (Jun 2002). "JunB potentiates function of BRCA1 activation domain 1 (AD1) ... Hsu JC, Bravo R, Taub R (1992). "Interactions among LRF-1, JunB, c-Jun, and c-Fos define a regulatory program in the G1 phase ... Schütte J, Viallet J, Nau M, Segal S, Fedorko J, Minna J (Feb 1990). "jun-B inhibits and c-fos stimulates the transforming and ... Nomura N, Ide M, Sasamoto S, Matsui M, Date T, Ishizaki R (1990). "Isolation of human cDNA clones of jun-related genes, jun-B ...
"LPA stimulates intestinal DRA gene transcription via LPA2 receptor, PI3K/AKT, and c-Fos-dependent pathway". American Journal of ... "Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic ... "Entrez Gene: SLC26A3 solute carrier family 26, member 3". Sterling D, Brown NJ, Supuran CT, Casey JR (November 2002). "The ... Mutations in this gene have been associated with congenital chloride diarrhoea, a treatable disease. The congenital absence of ...
Sheng, M., & Greenberg, M. E. (1990). The regulation and function of c-fos and other immediate early genes in the nervous ... Since then, a wealth of research has been done to clarify the mechanisms, genes, and proteins involved in the physiological ... Many genes are upregulated during sleep, and therefore there is a possibility that protein synthesis is active in sleep- ... others suggest that the genes are byproducts of the LTP signaling pathway and are not directly involved in LTP. However, ...