Pol (DNA polymerase) refers to a gene in retroviruses, or the protein produced by that gene. Products of pol include: Common to ... Products,+pol at the U.S. National Library of Medicine Medical Subject Headings (MeSH) pol+Gene+Products,+Human+ ... HIV's gag and pol genes do not produce their proteins in their final form, but as larger combination proteins; the specific ...

Fernandez-Pol JA, Klos DJ, Hamilton PD (Aug 1994). "Metallopanstimulin gene product produced in a baculovirus expression system ... Fernandez-Pol JA, Klos DJ, Hamilton PD (Oct 1993). "A growth factor-inducible gene encodes a novel nuclear protein with zinc ... "Entrez Gene: RPS27 ribosomal protein S27 (metallopanstimulin 1)". Fernandez-Pol JA (1996). "Metallopanstimulin as a novel tumor ... As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through ...

Gag gene products associate with other retrotransposon transcripts to form virus-like particles. Pol gene products include ... Mutations caused by retrotransposons include: Gene inactivation Changing gene regulation Changing gene products Acting as DNA ... These genes overlap so they encode a protease that processes the resulting transcript into functional gene products. ... They differ by the order of sequences in pol genes. Env genes are found in LTR retrotransposon types Ty1-copia (Pseudoviridae ...

The gag gene provides the basic physical infrastructure of the virus, and pol provides the basic mechanism by which ... HIV employs a sophisticated system of differential RNA splicing to obtain nine different gene products from a less than 10kb ... tev: This gene is only present in a few HIV-1 isolates. It is a fusion of parts of the tat, env, and rev genes, and codes for a ... "Evidence of a novel RNA secondary structure in the coding region of HIV-1 pol gene". RNA. 14 (12): 2478-88. doi:10.1261/rna. ...

Due to the range of genes that Pol II transcribes, this is the polymerase that experiences the most regulation by a range of ... In humans, RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized ... processes for a group of genes useful under a specific conditions (for example, DNA repair genes or heat shock genes). ... An expressed gene is preferentially located outside of its chromosome territory, but a closely linked, inactive gene is located ...

This product may be protein (as is the case in the majority of genes) or may be RNA (as is the case of genes that code for tRNA ... Many noncoding genes in eukaryotes have different transcription termination mechanisms and they do not have pol(A) tails. Many ... Gene dosage Gene expression Gene family Gene nomenclature Gene patent Gene pool Gene redundancy Genetic algorithm Haplotype ... There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression, the DNA is first ...

This gene is part of an HERV provirus on human chromosome 19 that has inactivating mutations in the gag and pol genes. This ... The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic ... "Entrez Gene: Endogenous retrovirus group V member 2, envelope". Retrieved 2017-09-13. This article incorporates text from the ... Endogenous retrovirus group V member 2, envelope is a protein that in humans is encoded by the ERVV-2 gene. Many human ...

... indicating the gene product is involved in G2 arrest. M: A mutant screen of budding yeasts with mitotic arrest identified CDC16 ... S: Schizosaccharomyces pombe (fission yeast) expressing a temperature-sensitive mutant form of DNA polymerase delta (pol delta ... Genetic engineering of cells with specific gene knockouts can also result in cells that arrest at different phases of the cell ... Hwang LH, Murray AW (October 1997). "A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in ...

These viruses have genes called accessory genes, in addition to gag, pro, pol and env genes. Accessory genes are located ... These two glycoprotein products stay in close affiliation, and they are transported to the plasma membrane after further ... In example, for the gag gene; it is translated into molecules of the capsid protein, and for the pol gene; it is translated ... The proteins encoded by the gag and pol genes are translated from genome-length mRNAs into Gag and Gag-Pol polyproteins. ...

The function of the auxiliary gene vif is not fully known. The vif gene product, a 29 kDa protein, induces a weak immune ... The pol gene encodes five enzymatic functions: a reverse transcriptase, RNase H, dUTPase, integrase, and protease. The reverse ... The gag gene encodes three final glycoprotein products: the capsid, the nucleocapsid, and the matrix protein which links the ... The protease cleaves the gag and pol polyprotein precursor.[citation needed] The viral tat gene encodes a 94-amino acid protein ...

... however the orfA-encoded product may display many of the attributes of HIV-1 accessory gene products such as Vpr, Vpu or Nef.[ ... It has the typical genomic structure of retroviruses and includes LTR, vif, pol, gag, orfA, env, and rev genes. The Gag ... The Pol polyprotein is translated by ribosomal frame-shifting, a feature shared with HIV. Cleavage of Pol by the viral protease ... Of FIV's genome, Pol is the most conserved across FIV strains along with gag. On the contrary, env, vif, orfa, and rev are the ...

As a result, structural proteins, resulting from polypeptide products of gag and gag-pol genes, that are necessary for the HIV ...

... and pol. The env mRNA must be spliced for expression. The mature product of the env gene is the viral spike protein, which has ... Genes,+env at the U.S. National Library of Medicine Medical Subject Headings (MeSH) env+Gene+Products,+Human+Immunodeficiency+ ... Viral structural protein Gene+Products,+env at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Coffin JM ... Env expression is regulated by the gene product of rev. Experimental deletion of rev resulted in the inability to detect the ...

Protease PR encoded by the pro gene (part of pol gene in some viruses). dUTPase DU encoded by the pro gene (part of pol gene in ... They may also have additional accessory genes depending on the virus (e.g., for HIV-1: vif, vpr, vpu, nef) whose products are ... Enzymes: Reverse transcriptase RT encoded by the pol gene. Protein size 66000 Da. Integrase IN also encoded by the pol gene. ... As with all retroviruses, lentiviruses have gag, pol and env genes, coding for viral proteins in the order: 5´-gag-pol-env-3´. ...

Pol and Gag genes.[citation needed] GeoVax is currently conducting multiple site Phase 2 Human clinical trials for HIV/AIDS ... "Specifically, the HVTN plans to clinically test a novel vaccine product developed by GeoVax scientists that expresses human ... With the GeoVax vaccine a variety of HIV proteins (both surface and internal) are expressed from genes which include the Env, ... vaccine both of which lead to the insertion of genes into primate DNA which leads to foreign protein expression. ...

Though the protein was originally identified as a Topoisomerase I redundant factor, the TRF4 gene product was later shown to be ... The cell off-loads the processive replication polymerase and instead uses Pol σ for synthesis of the CAR region. It has been ... The Pds5 gene was also identified in yeast as necessary for the establishment of cohesion. In humans, the gene has two homologs ... The Eco1/Ctf7 gene (yeast) was one of the first genes to be identified as specifically required for the establishment of ...

Later, the proximity of spf to polA (gene encoding DNA polymerase I) led Polayes and co-workers to test whether the products of ... the DNA pol A activity was reduced. The underlying mechanism for this observation remains however unknown. Spot42 can interact ... the abnormal responses was caused by an elevated number of excessive Spot42 RNA gene products rather than excess of the gene ... During overexpression of Spot 42 sixteen different genes show 2-fold elevated levels of mRNA. The identified genes are mostly ...

... gag-pol MeSH D12.776.964.970.600.850.350.400 - hiv core protein p24 MeSH D12.776.964.970.600.850.375 - gene products, pol (gene ... gene products, rev (HIV) MeSH D12.776.964.950.800.400 - gene products, tat MeSH D12.776.964.950.800.410 - gene products, tax ... gene products, rex MeSH D12.776.964.700.750.480 - gene products, tax (gene) MeSH D12.776.964.700.750.650 - oncogene protein ... gene products, rex MeSH D12.776.964.775.750.480 - gene products, tax MeSH D12.776.964.775.750.650 - oncogene protein gp140(v- ...

miRNA genes are usually transcribed by RNA polymerase II (Pol II). The polymerase often binds to a promoter found near the DNA ... The product resulting has a two-nucleotide overhang at its 3' end; it has 3' hydroxyl and 5' phosphate groups. It is often ... The miRNAs encoding genes are also named using the same three-letter prefix according to the conventions of the organism gene ... Several genes involved in DNA repair are regulated by microRNAs. Germ line mutations in DNA repair genes cause only 2-5% of ...

The Gag and Pol genes are encoded in the same mRNA. Depending on the host species, two different strategies can be used to ... groups based on both their degree of sequence similarity and the order of encoded gene products. Ty1-copia and Ty3-Metaviridae ... The Pol gene produces three proteins: a protease (PR), a reverse transcriptase endowed with an RT (reverse-transcriptase) and ... All functional LTR-retrotransposons encode a minimum of two genes, gag and pol, that are sufficient for their replication. Gag ...

The virus comprises 5' and 3' LTRs and three genes: Gag (structural), Pol (enzymes) and Env (envelope and transmembrane); the ... "LTCI Product Information". T-Cyte Therapeutics, Inc. Archived from the original on August 16, 2012. Retrieved July 28, 2012. "T ... The absence of any observed adverse events in several animal species suggests that the product has a very low toxicity profile ... Merial produces a recombinant vaccine consisting of canarypox virus carrying FeLV gag and env genes (sold as PUREVAX FeLV in ...

RNA Pol II-mediated gene transcription induces a local opening of chromatin state through the recruitment of histone ... it is possible that eRNAs simply represent the product of random "leaky" transcription and carry no functional significance. ... RNA pol II) binding and non-coding RNA transcription. The level of RNA pol II-enhancer interaction and RNA transcript formation ... June 2005). "Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase". ...

184 and 215 in the pol gene are observed more rarely. In 1992 dideoxycytidine was listed as a specialty drug. "zalcitabine ( ... Product information" (PDF). Roche. September 2002. Archived from the original (PDF) on 16 September 2009. Moyle GJ (August 1996 ...

RNase P exerts its role in transcription through association with Pol III and chromatin of active tRNA and 5S rRNA genes. It ... Leygue E (August 2007). "Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to ... The main function of miRNAs is to down-regulate gene expression. The ncRNA RNase P has also been shown to influence gene ... Gene. 408 (1-2): 172-9. doi:10.1016/j.gene.2007.10.037. PMC 6800007. PMID 18160232. Bolton PF, Veltman MW, Weisblatt E, Holmes ...

Czekaj, P (2000). "Phenobarbital-induced expression of cytochrome P450 genes". Acta Biochim. Pol. 47 (4): 1093-105. doi: ... Taking phenobarbital-containing products, such as Corvalol, while taking other medications may reduce their effectiveness. Some ... According to the Farmak product label, the composition of 1 tablet is as follows: Ethyl ester of α-bromoisovaleric acid - 12.42 ... Phenobarbital is a central nervous system depressant.[medical citation needed] According to the Farmak product label of ...

"Entrez Gene: VCP valosin-containing protein". Ogura T, Wilkinson AJ (July 2001). "AAA+ superfamily ATPases: common structure-- ... Even without evidence that valosin is a physiological product, the VCP nomenclature continues to be used in the literature. VCP ... The identified VCP substrates include transcriptional repressor α2 and RNA polymerase (Pol) II complex and CMG DNA helicase in ... Mutations in VCP are an example of pleiotropy, where mutations in the same gene give rise to different phenotypes. The term ...

and Sinden and Cole presented evidence that a homologous recombinational repair process requiring the products of genes uvrA, ... Compared to several other TLS pols examined, pol η is likely to contribute to the TLS-mediated repair of the DOB-ICL in vivo. ... Among individuals with NSLC, low expression of the breast cancer 1 gene (BRCA1) in the primary tumor has correlated with ... of the bypass products were mutagenic containing substitutions or deletions. The increase in the size of unhooked repair ...

... all of which target integration to gene poor regions. Endogenous retrotransposons are hypothesized to target gene poor ... Pol. 45 (3): 627-43. doi:10.18388/abp.1998_4201. PMID 9918489. Zou S, Wright DA, Voytas DF (January 1995). "The Saccharomyces ... dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose". Proc. Natl. Acad. Sci. U.S.A. 97 (26 ... chromosomal targets in order to reduce the chance of inactivating host genes. Ty1-Ty4 integrate upstream of Pol III promoters, ...

García P, Arca P, Evaristo Suárez J (July 1995). "Product of fosC, a gene from Pseudomonas syringae, mediates fosfomycin ... Antonello RM, Principe L, Maraolo AE, Viaggi V, Pol R, Fabbiani M, et al. (August 2020). "Fosfomycin as Partner Drug for ... "Nucleotide sequence and intracellular location of the product of the fosfomycin resistance gene from transposon Tn2921". ... Antonello RM, Principe L, Maraolo AE, Viaggi V, Pol R, Fabbiani M, et al. (August 2020). "Fosfomycin as Partner Drug for ...

RNA polymerase I (Pol I) catalyses the transcription of all rRNA genes except 5S. These rRNA genes are organised into a single ... "Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product". Nature. 330 (6147): 489-93. ... The additional subunits found in Pol I and Pol III relative to Pol II, are homologous to Pol II transcription factors. Crystal ... The long poly-A tail is unique to transcripts made by Pol II. In the process of terminating transcription by Pol I and Pol II, ...