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*  Long non-coding RNA
... such as the heat shock genes. This additional hierarchy of regulation that exempts individual genes from the generalised ... Li J, Witte DP, Van Dyke T, Askew DS (April 1997). "Expression of the putative proto-oncogene His-1 in normal and neoplastic ... July 2008). "Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta- ... A recent study observed an inverse expression profile of the p15 gene and an antisense ncRNA in leukaemia. A detailed analysis ...
*  THRSP
Ota Y, Mariash A, Wagner JL, Mariash CN (1997). "Cloning, expression and regulation of the human S14 gene". Mol. Cell. ... a metabolic integrator in normal and neoplastic cells". Thyroid. 8 (9): 815-25. doi:10.1089/thy.1998.8.815. PMID 9777755. ... The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and ... This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be ...
*  List of MeSH codes (G05)
... gene expression regulation, fungal MeSH G05.315.370 --- gene expression regulation, neoplastic MeSH G05.315.370.500 --- gene ... gene expression regulation, plant MeSH G05.315.385 --- gene expression regulation, viral MeSH G05.315.410 --- gene silencing ... gene amplification MeSH G05.315.290 --- gene expression regulation, archaeal MeSH G05.315.300 --- gene expression regulation, ... gene expression regulation, developmental MeSH G05.315.320 --- gene expression regulation, enzymologic MeSH G05.315.320.200 ...
*  DUT (gene)
Wilson PM, Fazzone W, LaBonte MJ, Lenz HJ, Ladner RD (Jan 2009). "Regulation of human dUTPase gene expression and p53-mediated ... "dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5- ... Notably, DUT expression is regulated by the tumor suppressor gene p53 in order to promote apoptosis of tumor cells.. Abnormal ... DUTP pyrophosphatase, also known as DUT, is an enzyme which in humans is encoded by the DUT gene on chromosome 15. This gene ...
*  SLC3A2
Lindsten T, June CH, Thompson CB, Leiden JM (1989). "Regulation of 4F2 heavy-chain gene expression during normal human T-cell ... a type II membrane glycoprotein involved in normal and neoplastic cell growth". Proc. Natl. Acad. Sci. U.S.A. 84 (18): 6526-30 ... 4F2hc/CD98 heavy subunit protein encoded by the SLC3A2 gene (this gene) CD98 light subunit protein encoded by the SLC7A5 gene ... "Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte ...
*  Middle tumor antigen
"Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous ... In MPyV, MTag is an efficient oncoprotein that can be sufficient to induce neoplastic transformation in some cells. The genes ... MTag plays a role in viral DNA replication and in the transition from early to late gene expression, and its absence can cause ... The LTag gene is usually encoded in two exons, of which the first overlaps with the genes for STag and MTag. The result of this ...
*  S100B
Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and ... S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number ... Peña LA, Brecher CW, Marshak DR (1997). "beta-Amyloid regulates gene expression of glial trophic substance S100 beta in C6 ... S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at ...
*  ID3 (gene)
Deed RW, Jasiok M, Norton JD (1998). "Lymphoid-specific expression of the Id3 gene in hematopoietic cells. Selective antagonism ... Deed RW, Hara E, Atherton GT, Peters G, Norton JD (1997). "Regulation of Id3 cell cycle function by Cdk-2-dependent ... helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic ... Evidence toward a novel mechanism regulating muscle-specific gene expression". J. Biol. Chem. 272 (4): 2459-63. doi:10.1074/jbc ...
*  Prostaglandin EP4 receptor
"Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage ... a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors". The Journal of Clinical ... Activation of ERK induces expression of EGR1, a transcription factor which controls transcription of genes involved in cellular ... Activated CREB stimulates the expression of genes such as c-fos, somatostatin, and corticotropin-releasing hormone that ...
*  Histone deacetylase
"Negative and positive regulation of gene expression by mouse histone deacetylase 1". Molecular and Cellular Biology. 26 (21): ... "Histone deacetylase inhibitors as anti-neoplastic agents". Cancer Letters. 280 (2): 192-200. doi:10.1016/j.canlet.2009.03.013. ... ko05220 Histone acetylation plays an important role in the regulation of gene expression. Hyperacetylated chromatin is ... in regulation of the parathyroid hormone gene". The EMBO Journal. 22 (23): 6299-309. doi:10.1093/emboj/cdg595. PMC 291836 . ...
*  RB1CC1
Bamba N, Chano T, Taga T, Ohta S, Takeuchi Y, Okabe H (Oct 2004). "Expression and regulation of RB1CC1 in developing murine and ... "RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells". International Journal of Molecular ... "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) ... characterization and mapping of the mouse and human RB1CC1 genes". Gene. 291 (1-2): 29-34. doi:10.1016/S0378-1119(02)00585-1. ...
*  PAX8
Down regulation of the PAX gene expression inhibits cell growth and induces apoptosis. This could be a possible avenue for ... Expression of PAX8 is increased in neoplastic renal tissues, Wilms tumors, ovarian cancer and Müllerian carcinomas. For this ... Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. This gene is a member of the ... it is possible that it regulates expression of genes other than thyroid-specific. Several known tumor suppressor genes like ...
*  ING1
"Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues". Hybridoma and ... "Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1)". Molecular and ... Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced ... Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene. This gene encodes a tumor suppressor ...
*  UPK1A
"Uroplakin gene expression by normal and neoplastic human urothelium". Am J Pathol. 153 (6): 1957-67. doi:10.1016/S0002-9440(10) ... The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and ... Yuasa T, Yoshiki T, Isono T, Tanaka T, Hayashida H, Okada Y (Sep 1999). "Expression of transitional cell-specific genes, ... Uroplakin-1a is a protein that in humans is encoded by the UPK1A gene. The protein encoded by this gene is a member of the ...
*  Carcinogenesis
Key factor in healing is the regulation of cytokine gene expression, which enables complementary groups of cells to respond to ... These early neoplastic changes must be distinguished from hyperplasia, a reversible increase in cell division caused by an ... In either case, expression of these genes promotes the malignant phenotype of cancer cells. Tumor suppressor genes are genes ... Epigenetics is the study of the regulation of gene expression through chemical, non-mutational changes in DNA structure. The ...
*  PKM2
... is regulated on several cellular levels, including gene expression, alternative splicing and post-translational ... "Regulation of glycolysis by Raf protein serine/threonine kinases". Advances in Enzyme Regulation. 42: 317-32. doi:10.1016/S0065 ... Ignacak J, Stachurska MB (Mar 2003). "The dual activity of pyruvate kinase type M2 from chromatin extracts of neoplastic cells ... The M-gene consists of 12 exons and 11 introns. PKM1 and PKM2 are different splicing products of the M-gene (exon 9 for PKM1 ...
*  Cell division cycle 7-related protein kinase
The gene, CDC7, is involved in the regulation of cell cycle because of the gene product Cdc7 kinase. The protein is expressed ... Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Additional transcript ... There are several ways its expression can be altered that leads to problems. In mouse embryonic stem cells (ESCs), Cdc7 is ... The Cdc7 kinase is involved in regulation of the cell cycle at the point of chromosomal DNA replication. The gene CDC7 appears ...
*  ENPP3
... the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy". Journal of ... "Entrez Gene: ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3". McGowan EC, Saini S (February 2013). "Update on the ... in inflammatory and neoplastic bile duct diseases". Cancer Letters. 207 (2): 139-47. doi:10.1016/j.canlet.2003.11.002. PMID ... Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The ...
*  Eukaryotic translation elongation factor 1 alpha 1
"Retinol-regulated gene expression in human tracheobronchial epithelial cells. Enhanced expression of elongation factor EF-1 ... These effects may be attributed to the resulting down-regulation of the PI3K/Akt/NF-κB and PI3K/Akt/mTOR signaling pathways. ... combined with altered levels of eEF1A-derived bacterial peptides in neoplastic disease, may lead to autoimmunity in breast ... Zheng C, Baum BJ (2014). "All human EF1α promoters are not equal: markedly affect gene expression in constructs from different ...
*  TGF alpha
Luetteke NC, Lee DC (1991). "Transforming growth factor alpha: expression, regulation and biological action of its integral ... This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. TGF-α ... "Distribution of immunoreactive transforming growth factor-alpha in non-neoplastic human salivary glands". Histol. Histopathol. ... Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal ...
*  List of intestinal stem cell marker genes
... expression marks slowly cycling intestinal stem cells". Proceedings of the National Academy of Sciences. 108 (1): 179-184. doi: ... "Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling". Nature Cell Biology. 14 (4): 401- ... "Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation". Nature. 457 (7229): 603-607. doi: ... "PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations". Proceedings of ...
*  Decorin
"Deficient expression of the gene coding for decorin in a lethal form of Marfan syndrome". The Journal of Biological Chemistry. ... The primary function of decorin involves regulation during the cell cycle. It has been involved in the regulation of autophagy ... multiple molecular targets of decorin-mediated suppression of neoplastic growth". Cell and Tissue Research. 296 (2): 221-7. doi ... There are multiple alternatively spliced transcript variants known for the decorin gene. Mutations in the decorin gene are ...
*  ERV3
... expression in various organs in vivo and its regulation in vitro". Leukemia. 11 Suppl 3: 145-6. PMID 9209324. Andersson AC, ... HERV-R_7q21.2 provirus ancestral Env polyprotein is a protein that in humans is encoded by the ERV3 gene. The human genome ... mRNA in normal and neoplastic tissues". International Journal of Oncology. 12 (2): 309-13. doi:10.3892/ijo.12.2.309. PMID ... "Entrez Gene: ERV3 endogenous retroviral sequence 3 (includes zinc finger protein H-plk/HPF9)". Sasaki T (November 1991). "[ ...
*  UPK1B
1998). "Uroplakin gene expression by normal and neoplastic human urothelium". Am. J. Pathol. 153 (6): 1957-67. doi:10.1016/ ... These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth ... "Uroplakin gene expression by normal and neoplastic human urothelium". Am. J. Pathol. 153 (6): 1957-67. doi:10.1016/S0002-9440( ... 1998). "Expression of uroplakin Ib and uroplakin III genes in tissues and peripheral blood of patients with transitional cell ...
*  MADD (gene)
... a novel human gene differentially expressed in normal and neoplastic cells". DNA Seq. 6 (5): 263-73. doi:10.3109/ ... Lim KM, Yeo WS, Chow VT (2004). "Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes ... Del Villar K, Miller CA (2004). "Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell ... MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha ...
*  60S ribosomal protein L7
Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene". The Journal of Biological Chemistry. 268 ( ... "Differential expression of ribosomal proteins in human normal and neoplastic colorectum". The Journal of Histochemistry and ... As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through ... This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ...
*  Aquaporin 3
2007). "Expression of aquaporin 3 (AQP3) in normal and neoplastic lung tissues". Hum. Pathol. 38 (1): 171-8. doi:10.1016/j. ... 2006). "Aquaporin 3 expression in human fetal membranes and its up-regulation by cyclic adenosine monophosphate in amnion ... GIL blood group system at BGMUT Blood Group Antigen Gene Mutation Database at NCBI, NIH Human AQP3 genome location and AQP3 ... Lee TC, Ho IC, Lu WJ, Huang JD (2006). "Enhanced expression of multidrug resistance-associated protein 2 and reduced expression ...