... including modulation of gene expression, cytoskeletal rearrangements, and regulation of enzymatic activities. The hydrolysis of ... Differential interaction of a fluorescent probe with the guanosine nucleotide complexes of bacterial elongation factor Tu". ... Downes, G. B.; Gautam, N. (1999-12-15). "The G protein subunit gene families". Genomics. 62 (3): 544-552. doi:10.1006/geno. ... Schmidt, Anja; Hall, Alan (2002-07-01). "Guanine nucleotide exchange factors for Rho GTPases: turning on the switch". Genes & ...
"A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. Typhimurium and E. Coli". Cell. 52 ... "A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene". Nature. 391 (6664 ... "DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri". Nature. 344 (6268): 789-792. ... Newbury, S. F.; Smith, N. H.; Higgins, C. F. (1987). "Differential mRNA stability controls relative gene expression within a ...
The phage genes specifying its regulation and DNA replication have typically been deleted, and expression of the cluster of ... Most of the RcGTA structural genes are encoded in a ~ 15 kb genetic cluster on the bacterial chromosome. However, other genes ... expression of gene transfer agent genes within a population during production and release of the Rhodobacter capsulatus gene ... These GTA-associated genes are often under coordinated regulation with the main GTA gene cluster. Phage-derived cell-lysis ...
... such as the nod genes). The expression and regulation of nif genes, while sharing common features in all or most of the ... The nif genes can be found on bacterial chromosomes, but in symbiotic bacteria they are often found on plasmids or symbiosis ... while the chromosomes contain most of the housekeeping genes of the bacteria. Regulation of the nif genes is at the ... The expression of the nif genes is induced as a response to low concentrations of fixed nitrogen and oxygen concentrations (the ...
... as a critical regulator of capsule expression. Fis is also involved in the regulation of a range of genes in bacterial ... fis is an E. coli gene encoding the Fis (or FIS) protein. The regulation of this gene is more complex than most other genes in ... Bradley MD, Beach MB, de Koning AP, Pratt TS, Osuna R (September 2007). "Effects of Fis on Escherichia coli gene expression ... Karambelkar S, Swapna G, Nagaraja V (May 2012). "Silencing of toxic gene expression by Fis". Nucleic Acids Research. 40 (10): ...
Epigenetic regulations such as DNA methylation and histone methylation can repress gene expression by inhibiting initiation of ... AsRNAs can be involved in this level of gene regulation. For example, in bacterial or eukaryotic cells where complex RNA ... gene. FLC gene in Arabidopsis thaliana encodes for a transcription factor that prevent expression of a range of genes that ... However, there is a need in developing drugs that can activate or upregulate gene expression such as tumor suppressor genes, ...
Gene Structure and Expression. 1625 (3): 305-8. doi:10.1016/s0167-4781(03)00017-4. PMID 12591618. Choi SK, Matsuda S, Hoshino T ... Linden H (September 1999). "Carotenoid hydroxylase from Haematococcus pluvialis: cDNA sequence, regulation and functional ... Peng X, Misawa N (October 2006). "Characterization of bacterial beta-carotene 3,3'-hydroxylases, CrtZ, and P450 in astaxanthin ... Gene Structure and Expression. 1446 (3): 203-12. doi:10.1016/s0167-4781(99)00088-3. PMID 10524195. Zhu C, Yamamura S, Nishihara ...
She is known for studying the regulation of transcription and host interactions that occur during bacterial virus infection. ... Rothman-Denes combines biophysical, biochemical and structural characterisation techniques to understand gene expression at the ... She studies how bacterial viruses impact the molecular processes within a host. She uncovered mechanisms of transcription ...
... mRNA Other Regulation of gene expression Cis-trans isomerism Gene regulatory network Operon Promoter Trans-acting factor Rfam ... Kortmann J, Narberhaus F (March 2012). "Bacterial RNA thermometers: molecular zippers and switches". Nature Reviews. ... a key component in the regulation of gene expression". Genes & Development. 16 (20): 2583-2592. doi:10.1101/gad.1026202. PMID ... Platt T (1986). "Transcription termination and the regulation of gene expression". Annual Review of Biochemistry. 55: 339-372. ...
In MarS deletion strains expression of mga and several Mga-activated genes is reduced. This down-regulation of virulence ... However, the lack of MarS increased bacterial dissemination and tolerance towards oxidative stress. Weinberg Z, Wang JX, Bogue ... The sRNA was shown to interact with the 5'UTR of the mga transcript (the multiple virulence gene regulator gene) and was ... First, in some cases, the asd RNA is not in the 5' untranslated region of any annotated gene. Second, in Streptococcus mutans, ...
... the expression of genes resulting from the activation of an activator. Positive regulation mechanisms subsequently proved to be ... that one of the proteins allowing the transport of maltose through the bacterial envelope serves as a receptor for a bacterial ... The unblocking of the genes thus results from the inhibition of the repressor . This regulation involving a double inhibition ... in the same bacterium led them to propose that the expression of genes encoding the enzymes necessary for the metabolism of ...
... molecules commonly used as communication signals between bacterial cells in a population to regulate certain gene expression ... This type of gene regulation is known as quorum sensing. Other names for these types of enzymes are Quorum-quenching N-acyl- ... Expression of virulence genes in E. Carotovora is regulated by N-(3-oxohexanoyl)-L-homoserine lactone (OHHL). Presumably, OHHL- ... hydrolysis via lactonase reduced OHHL levels, inhibiting the quorum-sensing systems driving virulence gene expression. 1,4- ...
Across all living organisms, regulation of gene expression is controlled by interactions between DNA-binding regulatory ... drives expression of downstream reporter genes. This reporter region facilitates both positive and negative selection by HIS3 ... bait-prey binding must be of high enough stringency to drive reporter gene expression (HIS3) at a sufficient level to overcome ... The bacterial one-hybrid (B1H) system is a method for identifying the sequence-specific target site of a DNA-binding domain. In ...
"Regulation of eukaryotic gene expression US Patent 4,833,080 (1989)". Retrieved January 6, 2015. Friedberg, Errol (October 2010 ... "Regulation of the cellular response to DNA damage" (1982) Brent, Roger; Ptashne, Mark (1984). "A bacterial repressor protein or ... Regulation of Eukaryotic Gene Expression, with Mark Ptashne). Dr. Brent is the inventor on 16 additional US patents and four ... Roger Brent (born December 28, 1955) is an American biologist known for his work on gene regulation and systems biology. He ...
Deng, M.; Lancto, C. A.; Abrahamsen, M. S. (2004). "Cryptosporidium parvum regulation of human epithelial cell gene expression ... Amann R, Springer N, Schönhuber W, Ludwig W, Schmid EN, Müller KD, Michel R (January 1997). "Obligate intracellular bacterial ... Bacterial examples include: Bartonella henselae Francisella tularensis Listeria monocytogenes Salmonella Typhi Brucella ... "Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth". Science. 334 (6062): 1553-7. ...
Sequence-specific activation of gene expression refers to CRISPR activation (CRISPRa). Based on the bacterial genetic immune ... Together, sgRNA and dCas9 constitute a minimal system for gene-specific regulation. CRISPRi can sterically repress ... CRISPRi can influence genes that are in close proximity to the target gene. This is especially important when targeting genes ... is that CRISPRi regulates gene expression primarily on the transcriptional level, while RNAi controls genes on the mRNA level. ...
Regulation of gene expression is the control of the amount and timing of appearance of the functional product of a gene. ... COLOMBOS: collection of bacterial expression compendia. Many Microbe Microarrays Database: microbial Affymetrix data AlloMap ... A facultative gene is a gene only transcribed when needed as opposed to a constitutive gene. An inducible gene is a gene whose ... Regulation of gene expression gives control over the timing, location, and amount of a given gene product (protein or ncRNA) ...
... there is also environmental regulation of AK-HSD gene expression. Light exposure has been demonstrated to increase expression ... Thomas D, Barbey R, Surdin-Kerjan Y (June 1993). "Evolutionary relationships between yeast and bacterial homoserine ... "Expression of an Aspartate Kinase Homoserine Dehydrogenase Gene IS Subject to Specific Spatial and Temporal Regulation in ... Zhu-Shimoni JX, Galili G (March 1998). "Expression of an Arabidopsis Aspartate Kinase/Homoserine Dehydrogenase Gene Is ...
Bierne and colleagues further discovered the function of BAHD1 in the regulation of chromatin structure and gene expression. ... Bahd1-haplodeficiency in mice decreases the efficiency of infection with the bacterial pathogen Listeria monocytogenes. During ... v t e (CS1: long volume value, Genes on human chromosome 15, Human proteins, All stub articles, Human chromosome 15 gene stubs) ... acts as an inhibitor of BAHD1 and activates interferon-stimulated genes. The BAHD1 gene is downregulated in the colon tissue in ...
... a bacterial expression clone may include a ribosome binding site (Shine-Dalgarno sequence) to enhance translation of the gene ... specialized type of cloning vector in which the transcriptional and translational signals needed for the regulation of the gene ... An example would be using an expression library to isolate genes that could confer antibiotic resistance. Expression vectors ... The transcriptional and translational signals may be synthetically created to make the expression of the gene of interest ...
"Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review". Genes. 8 (1): 43. doi:10.3390/genes8010043. ... July 2020). "A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing". Nature. 583 (7817): 631-637 ... O'Grady EP, Sokol PA (2011-12-09). "Burkholderia cenocepacia differential gene expression during host-pathogen interactions and ... "Burkholderia cenocepacia differential gene expression during host-pathogen interactions and adaptation to the host environment ...
Tétart F, Bouché JP (March 1992). "Regulation of the expression of the cell-cycle gene ftsZ by DicF antisense RNA. Division ... "Division inhibition gene dicF of Escherichia coli reveals a widespread group of prophage sequences in bacterial genomes". ... DicF RNA is a non-coding RNA that is an antisense inhibitor of cell division gene ftsZ. DicF is bound by the Hfq protein which ...
The PreQ1-I riboswitch is a cis-acting element identified in bacteria which regulates expression of genes involved in ... Like any other riboswitch, the two most common types of gene regulation mediated by preQ1 riboswitch are through transcription ... Ligand binding to the transcriptional riboswitch in bacterial causes modification in the structure of riboswitch unit, which ... signaling for gene expression. The docking and undocking mechanism are observed to be affected not only by the ligand, but also ...
"Unique role for translation initiation factor 3 in the light color regulation of photosynthetic gene expression". Proceedings ... IF3 is not universally found in all bacterial species. However, in E. coli, it is required for the 30S subunit to bind to the ... In molecular biology, translation initiation factor IF-3 (gene infC) is one of the three factors required for the initiation of ... Liveris D, Schwartz JJ, Geertman R, Schwartz I (September 1993). "Molecular cloning and sequencing of infC, the gene encoding ...
... leukotoxin expression can be highly variable between strains In bacteria, small RNAs are involved in gene regulation. Jorth et ... Africa CW, Nel J, Stemmet M (July 2014). "Anaerobes and bacterial vaginosis in pregnancy: virulence factors contributing to ... variable leukotoxin expression b strain Y4, most frequently in localized aggressive periodontitis, high leukotoxin expression; ... Target prediction indicated possibility of sRNA interaction with several virulence genes. This study confirmed the presence of ...
Morgenstein RM, Szostek B, Rather PN (September 2010). "Regulation of gene expression during swarmer cell differentiation in ... Gué M, Dupont V, Dufour A, Sire O (October 2001). "Bacterial swarming: a biochemical time-resolved FTIR-ATR study of Proteus ... Howery KE, Clemmer KM, Şimşek E, Kim M, Rather PN (August 2015). Armitage JP (ed.). "Regulation of the Min Cell Division ... Proteus Genome Projects from Genomes OnLine Database Type strain of Proteus mirabilis at BacDive - the Bacterial Diversity ...
In Reading, he worked on hormonal regulation of gene expression. He was a Commonwealth Scholar in the UK. Faruque joined the ... His team has also conducted cutting-edge research in CRISPR-Cas systems carried by bacterial viruses such as the JSF series of ... "Foodborne and Waterborne Bacterial Pathogens: Epidemiology, Evolution and Molecular Biology". Caister Academic Press. Retrieved ... Currently Faruque and his team have been studying the role of quorum sensing and bacterial communication through molecular ...
The expression of many thousands of genes are regulated by ncRNAs. This regulation can occur in trans or in cis. There is ... C. elegans was shown to learn and inherit pathogenic avoidance after exposure to a single non-coding RNA of a bacterial ... act to promote gene expression.[citation needed] In higher eukaryotes microRNAs regulate gene expression. A single miRNA can ... 2012). Non-coding RNAs and Epigenetic Regulation of Gene Expression: Drivers of Natural Selection. Caister Academic Press. ISBN ...
With a better understanding of fungal gene regulation and expression, we can expect filamentous fungi to become a possibly ... "Heterologous Expression of Genes in Bacterial, Fungal, Animal, and Plant Cells". Annual Review of Plant Physiology and Plant ... Heterologous expression refers to the expression of a gene or part of a gene in a host organism that does not naturally have ... This host is called the "expression system". Homologous expression, on the other hand, refers to the overexpression of a gene ...
Farmer, E. E.; Johnson, R. R.; Ryan, C. A. (March 1992). "Regulation of expression of proteinase inhibitor genes by methyl ... The Effects of Bacterial and Jasmonic Acid Treatments on Insects of Canola. 2008. "Success for plants' pest control". BBC News ... The Dgl gene is responsible for maintaining levels of JA during usual conditions in Zea mays as well as the preliminary release ... When plants are attacked by insects, they respond by releasing JA, which activates the expression of protease inhibitors, among ...