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*  Trimethylglycine
"Betaine improves the PCR amplification of GC-rich DNA sequences". Nucleic Acids Res. 25 (19): 3957-3958. doi:10.1093/nar/25.19. ... and prevents problems associated with the amplification and sequencing of GC-rich regions. Trimethylglycine makes guanosine and ... and other DNA polymerase-based assays such as DNA sequencing. By an unknown mechanism, it aids in the prevention of secondary ...
*  Betaine
Henke, W; Herdel, K; Jung, K; Schnorr, D; Loening, SA (1997). "Betaine improves the PCR amplification of GC-rich DNA sequences ... to polymerase chain reactions improves the amplification of DNA by reducing the formation of secondary structure in GC-rich ...
*  KLF13
These transcription factors bind to GC-rich sequences and related GT and CACCC boxes. KLF13 was first described as the RANTES ... "Functional domains and DNA-binding sequences of RFLAT-1/KLF13, a Krüppel-like transcription factor of activated T lymphocytes ... "Functional domains and DNA-binding sequences of RFLAT-1/KLF13, a Krüppel-like transcription factor of activated T lymphocytes ...
*  BNC1
Tang W, Tseng H (1999). "A GC-rich sequence within the 5' untranslated region of human basonuclin mRNA inhibits its translation ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
*  TNP2
Kundu TK, Rao MR (1995). "DNA condensation by the rat spermatidal protein TP2 shows GC-rich sequence preference and is zinc ... Kundu TK, Rao MR (1997). "Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2". ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... nucleotide sequence, assignment to the protamine gene cluster, and evidence for its low expression". Genomics. 14 (2): 377-83. ...
*  GCFC2
GC-rich sequence DNA-binding factor is a protein that in humans is encoded by the GCFC2 gene. The first mRNA transcript ... A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to ... 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40-5. doi:10.1038/ ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
*  PAXBP1
GC-rich sequence DNA-binding factor homolog is a protein that in humans is encoded by the PAXBP1 gene. Similarity to a ... 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40-5. doi:10.1038/ ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2000). "Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human ...
*  Massive parallel sequencing
AT-rich and GC-rich target sequences often show amplification bias, which results in their underrepresentation in genome ... Massive parallel sequencing or massively parallel sequencing is any of several high-throughput approaches to DNA sequencing ... This design is very different from that of Sanger sequencing-also known as capillary sequencing or first-generation sequencing- ... First, DNA sequencing libraries are generated by clonal amplification by PCR in vitro. Second, the DNA is sequenced by ...
*  CpG site
A 2002 study revised the rules of CpG island prediction to exclude other GC-rich genomic sequences such as Alu repeats. Based ... Given the frequency of GC two-nucleotide sequences, the number of CpG dinucleotides is much lower than would be expected. ... length of sequence {\displaystyle ({\text{number of }}C*{\text{number of }}G)/{\text{length of sequence}}} or ( ( number of C ... For example, in the human genome, which has a 42% GC content, a pair of nucleotides consisting of cytosine followed by guanine ...
*  TFAP2A
Its binding site is a GC-rich sequence that is present in the cis-regulatory regions of several viral and cellular genes. AP2- ... Human sequence as reference and searched for multispecies conserved sequences (MCSs). Regions contained in introns 5' and 3' ... Sequencing of candidate genes in that region in 4 additional unrelated BOFS patients revealed 4 different de novo missense ... A search of NSCL/P cases for potential regulatory elements for IRF6 gene was made aligning genomic sequences to a 500 Kb region ...
*  Pyruvate dehydrogenase (lipoamide) alpha 1
The DNA sequence in the transcription initiation site is very GC-rich. There is a "TATA box"-like sequence and a "CAAT present ... The preliminary peptide encoded by this gene was 29 amino acids at the very start of the sequence that correspond to a typical ... Koike K, Ohta S, Urata Y, Kagawa Y, Koike M (Jan 1988). "Cloning and sequencing of cDNAs encoding alpha and beta subunits of ... Koike K, Urata Y, Matsuo S, Koike M (Sep 1990). "Characterization and nucleotide sequence of the gene encoding the human ...
*  Testis-determining factor
Sp1 is a transcription factor that binds GC-rich consensus sequences, and mutation of the SRY binding sites leads to a 90% ... Specifically, it is the HMG region of TDF that binds to the minor groove of the DNA target sequence, causing the DNA to bend ... WT1 is transcription factor that has four C-terminal Zinc fingers and an N-terminal Pro/Glu-rich region and primarily functions ... Vilain E, McElreavey K, Jaubert F, Raymond JP, Richaud F, Fellous M (May 1992). "Familial case with sequence variant in the ...
*  Sepp Hochreiter
The analyses of these T cell chromatin sequencing data identified GC-rich long nucleosome-free regions that are hot spots of ... sequence classification) or generate an output sequence (sequence to sequence mapping). Neural networks with LSTM cells solved ... "Genome-wide chromatin remodeling identified at GC-rich long nucleosome-free regions". PLOS ONE. 7 (11): e47924. doi:10.1371/ ... cn.MOPS estimates the local DNA copy number, is suited for both whole genome sequencing and exom sequencing, and can be applied ...
*  ZNF281
... by the yeast one-hybrid screening with a GC-rich target sequence". FEBS Lett. 453 (3): 369-374. doi:10.1016/S0014-5793(99)00754 ... 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40-45. doi:10.1038/ ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 1999). "Identification of human GC-box-binding zinc finger protein, a new Krüppel-like zinc finger protein, ...
*  Satellite DNA
... of a GC-rich sequence consisting of repeats of a ~2100 base pair (bp) sequence called RU. The RU was arranged in long tandem ... Several RU sequences were cloned and sequenced to reveal conserved regions of conventional DNA sequences interspersed with five ... Conserved sequences showed virtually no differences among cloned RU sequences. Variations among cloned RU sequences were ... interrupting the pyrimidine-rich strand and T (pyrimidine) interrupting the purine-rich strand. This sequence feature adopted a ...
*  Kruppel-like factors
... acids that are predicted to interact with DNA are identical and the two compete for the same CACCC element or GC-rich sequence ... C2H2-type zinc finger structural motifs that bind to the GC-rich regions in DNA and regulate various cellular functions, such ...
*  Utricularia gibba
The presence of numerous GC-rich sequences throughout the nuclear genome of U. gibba is considered to have created a molecular ... The sequencing of its DNA revealed only 3% non-coding material. Utricularia gibba is an aquatic carnivorous plant that belongs ... gibba was sequenced. At only 82 megabases, the genome is exceptionally small for a multicellular plant. Despite its size, the ... "The study further challenges simplistic accounts of genome biology that assume functions for most or all DNA sequences, without ...
*  Chromosome 21 (human)
... encoding protein GC-rich sequence DNA-binding factor homolog CBS: cystathionine-beta-synthase CLDN14: claudin 14 CRYZL1: ... generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk. Antonarakis SE, Lyle R, Dermitzakis ET, ... Chromosome 21 was the second human chromosome to be fully sequenced, after chromosome 22. The following are some of the gene ... gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively ...
*  Leaky scanning
Eukaryotic genes containing consistent G-C rich leader sequences are frequently observed performing this mechanism. It is ... A weak context occurs when the sequences adjacent to the AUG start codon has deviated from the consensus sequence. A few ... The AUG codon in mammals is optimally recognized by the context GCCRCCAUGG, also known as a "Kozak Consensus Sequence." Purine ... R) and each of the nucleotides within this sequence are highly conserved and provide an important function in recognition and ...
*  KLF11
It binds to SP1- like GC- rich sequences in epsilon and gamma globin gene promoters inhibiting cellular growth and causing ... high-throughput expressed sequence tag sequencing analysis". Genomics. 79 (1): 7-17. doi:10.1006/geno.2001.6683. PMID 11827452 ...
*  Acidithiobacillus caldus
With a length of 2,932,225 base pairs, the genomic sequence of A. caldus is GC-rich with a GC content (mol%) in the range of ... Valdes, J.; Quatrini, R.; Hallberg, K.; Dopson, M.; Valenzuela, P. D. T.; Holmes, D. S. (2009). "Draft Genome Sequence of the ... Phylogenetic analysis of ITS sequences was sufficient to differentiate three unique species of Acidithiobacillus that were ... by sequence analyses of the PCR-amplified 16S-23S rDNA intergenic spacer (ITS) and restriction fragment length polymorphism. ...
*  Maximum subarray problem
In genomic sequence analysis, these problems include conserved segments, GC-rich regions, tandem repeats, low-complexity filter ... Genomic sequence analysis employs maximum subarray algorithms to identify important biological segments of protein sequences ... Maximum subarray algorithms are used for data analysis in many fields, such as genomic sequence analysis, computer vision, and ... access-date= requires ,url= (help) Richard S. Bird (1989). "Algebraic Identities for Program Calculation" (PDF). The Computer ...
*  List of MeSH codes (G06)
... base sequence MeSH G06.184.603.080.040 --- at rich sequence MeSH G06.184.603.080.380 --- gc rich sequence MeSH G06.184.603.080. ... carbohydrate sequence MeSH G06.184.603.580 --- conserved sequence MeSH G06.184.603.580.175 --- consensus sequence MeSH G06.184. ... sequence homology, amino acid MeSH G06.184.842.200.820 --- structural homology, protein MeSH G06.184.842.550 --- sequence ... repetitive sequences, nucleic acid MeSH G06.184.603.080.708.330 --- interspersed repetitive sequences MeSH G06.184.603.080. ...
*  DRIP-seq
In particular, typical short-read sequencing platforms would produce uneven read coverage in GC-rich regions. Sequencing long R ... Moreover, GC-rich regions tend to have low complexity by nature, which is difficult for short read aligners to produce unique ... immunoprecipitation ChIP-sequencing DNA sequencing Ginno, PA; Lott, PL; Christensen, HC; Korf, I; Chédin, F (30 March 2012). "R ... On the other hand, DRIP-seq relies on existing short-read sequencing platforms for the sequencing of R-loops. In other words, ...
*  TATA box
... which consists of G-C rich sequences. These secondary interactions induce bending of the DNA and helical unwinding. The degree ... the promoter contains an 8 bp AT-rich sequence located ~24 bp upstream of the transcription start site. This sequence was ... In the 1980s, while investigating nucleotide sequences in mouse genome loci, the Hogness box sequence was found and "boxed in" ... For example, one study used the adenovirus TATA promoter sequence (5'-CGCTATAAAAGGGC-3') as a model binding sequence and found ...
*  Halobacterium salinarum
The large chromosome is very G-C rich (68%). High GC-content of the genome increases stability in extreme environments. Whole ... Whole genome sequences are available for two strains of H. salinarum, NRC-1 and R1. The Halobacterium sp. NRC-1 genome consists ... 2000). "Genome sequence of Halobacterium species NRC-1". Proceedings of the National Academy of Sciences. 97 (22): 12176-81. ...