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*  Serum protein electrophoresis
... alpha-1 globulins, alpha-2 globulins, beta 1 and 2 globulins, and gamma globulins. Proteins are separated by both electrical ... The gamma globulins may be elevated (hypergammaglobulinemia), decreased (hypogammaglobulinaemia), or have an abnormal peak or ... C-reactive protein is found in between the beta and gamma zones producing beta/gamma fusion. IgA has the most anodal mobility ... resulting in a visible fibrinogen band between the beta and gamma globulins. The immunoglobulins or antibodies are generally ...
*  X-linked agammaglobulinemia
Most antibodies are gamma globulins. Antibodies are made mainly by plasma cells, which are daughter cells of the B cell line. ... Treatment with pooled gamma globulin cannot restore a functional population of B cells, but it is sufficient to reduce the ... which manifests as a complete or near-complete lack of proteins called gamma globulins, including antibodies, in their ...
*  Blood proteins
All blood proteins are synthesized in liver except for the gamma globulins. Separating serum proteins by electrophoresis is a ... Alpha 1 acid glycoprotein Alpha 1 fetoprotein alpha2-macroglobulin Gamma globulins Beta-2 microglobulin Haptoglobin ... Globulins make up 38% of blood proteins and transport ions, hormones, and lipids assisting in immune function. Fibrinogen ...
*  Gamma globulin
... although some immunoglobulins are not gamma globulins, and some gamma globulins are not immunoglobulins. Gamma globulin ... Gamma globulins are a class of globulins, identified by their position after serum protein electrophoresis. The most ... on how gamma globulin administration works in autoimmune disease is by overloading the mechanisms that degrade gamma globulins ... Intravenous gamma globulin was FDA-approved in 2004 to reduce antibodies in a patient with kidney failure to allow that person ...
*  Elvin A. Kabat
Kabat first demonstrated that antibodies are gamma globulins. He characterized the size and stunning heterogeneity of antibody- ...
*  Virginia Livingston
... gamma globulin, BCG) and antibiotics. Livingston prescribed antibiotics after cross testing them with patients' cultures to see ...
*  Elizabeth Press
FLEISCHMAN, JB; PORTER, RR; PRESS, EM (August 1963). "THE ARRANGEMENT OF THE PEPTIDE CHAINS IN GAMMA-GLOBULIN". The Biochemical ...
*  Cirrhosis
Findings include elevations in serum globulins, especially gamma globulins. Hereditary hemochromatosis. Usually presents with a ... Globulins - increased due to shunting of bacterial antigens away from the liver to lymphoid tissue. Serum sodium - hyponatremia ... Gamma-glutamyl transferase - correlates with AP levels. Typically much higher in chronic liver disease from alcohol. Bilirubin ...
*  Anti-nuclear antibody
"Blood factor in acute disseminated lupus erythematosus; determination of gamma globulin as specific plasma fraction." The ...
*  George Siber bibliography
Leszczynski, J; Gupta, CK; Siber, GR (Sep 1993). "The use of intravenous gamma globulin for CMV prophylaxis". Transplantation. ... Leszczynski, J; Gupta, CK; Siber, GR (Sep 1993). "The use of intravenous gamma globulin for CMV prophylaxis". Transplantation. ... Use of immune globulins in the prevention and treatment of infections. In: Remington J, Swartz M, eds. Current Clinical Topics ... Human hyperimmune globulins for bacterial infections in high-risk children. In: Cryz SJ, eds. Vaccines and Immunotherapy. New ...
*  Hypergammaglobulinemia
... is a medical condition with elevated levels of gamma globulin. It is a type of immunoproliferative ...
*  Autoimmune pancreatitis
Increased serum levels of gamma globulins, immunoglobulin G (IgG) or IgG4. The presence of serum autoantibodies such as anti- ... Laboratory data demonstrate abnormally elevated levels of serum gamma globulin and/or IgG, or the presence of autoantibodies. ...
*  Hyperimmunoglobulin E syndrome
High-dose intravenous gamma-globulin has also been suggested for the treatment of severe eczema in patients with HIES and ... Kimata H (1995). "High-dose intravenous gamma-globulin treatment for hyperimmunoglobulinemia E syndrome". J Allergy Clin ... Abnormal neutrophil chemotaxis due to decreased production of interferon gamma by T lymphocytes is thought to cause the disease ... "Defective interleukin-12/interferon-gamma pathway in patients with hyperimmunoglobulinemia E syndrome". J Pediatr. 136 (2): 176 ...
*  Evans syndrome
Nuss R, Wang W (1987). "Intravenous gamma globulin for thrombocytopenia in children with Evans syndrome". The American journal ...
*  Antibody
Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins". J. Exp. Med. 116 (2): 207-227. doi ... They constitute most of the gamma globulin fraction of the blood proteins. They are typically made of basic structural units- ... Rho(D) immune globulin antibodies are specific for human RhD antigen. Anti-RhD antibodies are administered as part of a ... Rho(D) Immune Globulin treatment prevents sensitization that can lead to Rh disease, but does not prevent or treat the ...
*  WHIM syndrome
... gammaglobulins) are often deficient. Infusions of immune globulin can reduce the frequency of bacterial infections, and G-CSF ... this trial showed no increase of immune globulins in the body. A phase III clinical trial has been approved to compare the ...
*  Jeanne Lusher
Intravenous gamma globulin treatment for chronic idiopathic thrombocytopenic purpura in children. Am J Med 1984;76:193-8. ...
*  Bacteriophage T12
Emerging treatments for strep TSS include clindamycin and intravenous gamma-globulin. The presence of lysogenic bacteriophage ... and gamma-interferon).These cytokines(TNFα, TNFβ) seem to mediate the fever, shock and organ failure characteristic of the ...
*  Arne Tiselius
Putnam, F. W. (1993). "Alpha-, beta-, gamma-globulin-Arne Tiselius and the advent of electrophoresis". Perspectives in biology ...
*  Polio vaccine
Hammon W, Coriell L, Wehrle P, Stokes J; Coriell; Wehrle; Stokes Jr (1953). "Evaluation of Red Cross gamma globulin as a ... and the demonstration that administration of antibodies in the form of gamma globulin protects against paralytic polio. The U.S ...
*  History of poliomyelitis
1954). "Evaluation of Red Cross gamma globulin as a prophylactic agent for poliomyelitis. 5. Reanalysis of results based on ... Rinaldo C (2005). "Passive Immunization Against Poliomyelitis: The Hammon Gamma Globulin Field Trials, 1951-1953". Am J Public ...
*  William Hammon
Rinaldo CR (2005). "Passive Immunization Against Poliomyelitis: The Hammon Gamma Globulin Field Trials, 1951-1953". American ...
*  Poliomyelitis
Hammon proposed the gamma globulin, which contained antibodies to poliovirus, could be used to halt poliovirus infection, ... The results of a large clinical trial were promising; the gamma globulin was shown to be about 80 percent effective in ... Due to the limited supply of blood plasma gamma globulin was later deemed impractical for widespread use and the medical ... In 1950, William Hammon at the University of Pittsburgh purified the gamma globulin component of the blood plasma of polio ...
*  William Freer Bale
Biophys., 48(2), 361-9 (1954). L. L. Miller, W. F. Bale, Synthesis of all plasma protein fractions except gamma globulins by ... gamma globulins the chief plasma protein fraction produced by non-hepatic tissues, J. Exp. Med., 99(2), 133-53 (1954). W. F. ... High specific activity iodination of gamma-globulin with iodine-131 monochloride, ORINS Rep US At Energy Comm, UR-568:, 1-18 ( ... High specific activity iodination of gamma-globulin with iodine-131 monochloride, Cancer Res., 20: 1495-1500 (1960). W. F. Bale ...
*  Oligopeptide
A tetrapeptide manufactured in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic ... The peptide is located in the Fd fragment of the gamma-globulin molecule. Oligoester Oligomer Oligopeptidase Peptide synthesis ...
*  Rituximab
Third-generation anti-CD20s such as obinutuzumab have a glycoengineered Fc fragment (Fc) with enhanced binding to Fc gamma ... "Treatment of Pemphigus Vulgaris with Rituximab and Intravenous Immune Globulin". N Engl J Med. 355: 1772-1779. doi:10.1056/ ...
*  Dysgammaglobulinemia
It is distinguished from hypogammaglobulinemia, which is a reduction in all types of gamma globulins. Hyper IgM syndrome can be ... Dysgammaglobulinemia is a type of immune disorder characterized by a reduction in some types of gamma globulins, resulting in ... Andre Cruchaud et al.: "The site of synthesis of the 19S T-globulins in dysgammaglobulinemia" (1962). Accessed 2009-07-17.. ...