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*  Neural tube defect
... only general food fortification with folic acid reduces neural tube defects While there have been concerns about folic acid ... A diet rich in natural folate (350 μg/d) can show as much increase in plasma folate as taking low levels of folic acid (250 μg/ ... Supplementing folic acid during pregnancy reduces the prevalence of NTDs by not exposing this otherwise sub-clinical mutation ... 747-52 Daly S, Mills JL, Molloy AM, Conley M, Lee YJ, Kirke PN, Weir DG, Scott JM (1997). "Minimum effective dose of folic acid ...
*  Methylenetetrahydrofolate reductase deficiency
... elevated plasma homocysteine levels have sometimes been treated with Vitamin B12 and low doses of folic acid. Although this ...
*  Antifolate
... the actions of folic acid (vitamin B9). Folic acid's primary function in the body is as a cofactor to various ... Folic acid Methotrexate Pemetrexed Raltitrexed Pralatrexate The name antifolate usually refers to drugs whose folate antagonism ... Both high-folate diets and supplemental folic acid may help reduce the toxic side-effects of low-dose methotrexate without ... Morgan SL, Baggott JE, Lee JY, Alarcon GS (1998). "Folic acid supplementation prevents deficient blood folate levels and ...
*  Folate deficiency
... is a low level of folic acid and derivatives in the body. Also known as vitamin B9, folate is involved in ... ISBN 978-1-4557-7566-8. Oakley GP Jr; Adams MJ; Dickinson CM (1996). "More folic acid for everyone, now". Journal of Nutrition ... ISBN 978-0-8036-2505-1. Hoffbrand, AV; Weir, DG (2001). "The history of folic acid". Br J Haematol. 113 (3): 579-589. doi: ... However, it may be counterproductive to take a folic acid supplement with methotrexate in cancer treatment. Folate deficiency ...
*  Ferrous salt/folic acid
... is a supplement used to prevent iron deficiency and folic acid deficiency during pregnancy. It can also ... Ferrous salt/folic acid was approved for medical use in the United States as early as 1946. It is on the World Health ... "Ferrous sulfate and folic acid medical facts from Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. ... It is a fixed dose combination of ferrous salt and folic acid. It is taken by mouth. Side effects may include dark stools, ...
*  Fragile site, folic acid type, rare, fra(2)(q13)
... is a protein that in humans is encoded by the FRA2B gene. "Human PubMed ... Reference:". "Entrez Gene: Fragile site, folic acid type, rare, fra(2)(q13)". Retrieved 2017-04-04. ...
*  DMOZ - Health: Nutrition: Nutrients: Vitamins and Minerals: Folic Acid
Go Folic! Women's Nutrition Project This San Francisco Department of Public Health project works to increase folic acid intake ... Folic Acid Canada A website run by the Spina Bifida & Hydrocephalus Association of Ontario with the goal of reducing the ... Information on folic acid with FAQ, quiz, and current news regarding FDA regulations. ... incidence of neural tube defects by promoting the consumption of folic acid. ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: F: Folic Acid: With B6 and B12
Health Pharmacy Drugs and Medications F Folic Acid With B6 and B12 0 ...
*  Pregnancy
... are fortified with folic acid. DHA omega-3 is a major structural fatty acid in the brain and retina, and is naturally found in ... Adequate intake of folic acid, and iron is often recommended. In developed areas, such as Western Europe and the United States ... "Folic acid, iron and pregnancy - Canada.ca". www.canada.ca. Archived from the original on 7 August 2017. Retrieved 25 August ... "Folic acid in diet: MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Archived from the original on 17 November 2015. ...
*  Infant mortality
Folic acid for mothers is one way to combat iron deficiency. A few public health measures used to lower levels of iron ... It is important that women of reproductive age adopt healthy behaviors in everyday life, such as taking folic acid, maintaining ... ISBN 0-674-05054-1. Folic Acid. National Center for Biotechnology Information, U.S. National Library of Medicine Gortmaker SL ( ...
*  Cofactor (biochemistry)
Donnelly JG (2001). "Folic acid". Crit Rev Clin Lab Sci. 38 (3): 183-223. doi:10.1080/20014091084209. PMID 11451208. Søballe B ... Vitamins can serve as precursors to many organic cofactors (e.g., vitamins B1, B2, B6, B12, niacin, folic acid) or as coenzymes ... This increases the functionality of the protein; unmodified amino acids are typically limited to acid-base reactions, and the ... Later, in 1949, Morris Friedkin and Albert L. Lehninger proved that NAD+ linked metabolic pathways such as the citric acid ...
*  Nutrition
... each of which an omega-3 fatty acid contained in fish oil but not in flaxseed oil), vitamin B12, folic acid, and inositol.[ ... Fatty acids such as conjugated linoleic acid, catalpic acid, eleostearic acid and punicic acid, in addition to providing energy ... As there is no protein or amino acid storage provision, amino acids must be present in the diet. Excess amino acids are ... Whitley JR, O'Dell BL, Hogan AG (September 1951). "Effect of diet on maze learning in second generation rats; folic acid ...
*  Spina bifida
"Folic Acid - Public Health Agency of Canada". Archived from the original on 2006-09-27. "Why do I need folic acid?". NHS Direct ... This risk can be reduced with folic acid supplementation before pregnancy. For the general population, low-dose folic acid ... amount of folic acid for women of childbearing age and women planning to become pregnant is at least 0.4 mg/day of folic acid ... Adding folic acid to flour has been found to be effective for most women. Open spina bifida can be surgically closed before or ...
*  Human nutrition
... each of which are an omega-3 fatty acid contained in fish oil, but not in flaxseed oil), vitamin B12, folic acid, and inositol ... The omega-3 eicosapentaenoic acid (EPA), which can be made in the human body from the omega-3 essential fatty acid alpha- ... An appropriate balance of essential fatty acids - omega-3 and omega-6 fatty acids - seems also important for health, though ... Other essential nutrients not classed as vitamins include essential amino acids (see above), essential fatty acids (see above ...
*  Causes of seizures
Folic acid in large amounts was considered to potentially counteract the antiseizure effects of antiepileptic drugs and ... Morrell, Martha J. (2002). "Folic Acid and Epilepsy". Epilepsy Currents. 2 (2): 31-34. doi:10.1046/j.1535-7597.2002.00017.x. ... nalidixic acid, and penicillin, though vitamin B6 taken along with them may prevent seizures; also, fluoroquinolones and ...
*  Neurodevelopmental disorder
"Folic Acid - March of Dimes". "Folate (Folacin, Folic Acid)". "Folic scid: topic home". Centers for Disease Control and ... The most common nutritional cause of neural tube defects is folic acid deficiency in the mother, a B vitamin usually found in ... Richardson, A.J.; Ross, M.A. (July 2000). "Fatty acid metabolism in neurodevelopmental disorder: a new perspective on ... Leukotrienes and Essential Fatty Acids. 63 (1-2): 1-9. doi:10.1054/plef.2000.0184. PMID 10970706. Nordham, Elizabeth A; ...
*  Food fortification
... folic acid intake leads to elevated blood concentrations of naturally occurring folates and of unmetabolized folic acid. High ... which is the case with folic acid used to increase folate intakes. Phytochemicals such as phytic acid in cereal grains can also ... Therefore, a high folic acid intake due to fortification may be harmful for more people than the policy is designed to help. ... For example, in the U.S., food is fortified with folic acid, which is one of the many naturally-occurring forms of folate, and ...
*  Kate Wilkinson (politician)
"Folic acid decision 'missed opportunity'". One News (New Zealand). Auckland. 1 September 2012. Retrieved 3 September 2012. " ... Paediatric Society Doctor Andrew Marshall said "making folic acid mandatory would prevent 10 to 20 birth defects, such as spina ... Wilkinson was criticised for her position on the mandatory addition of folic acid to bread sold to the public. ...
*  Esmond Emerson Snell
Hoffbrand, A. V.; Weir, D. G. (June 2001). "The history of folic acid". British Journal of Haematology. 113 (3): 579-589. doi: ... His notable discoveries using these methods include the discovery and naming of folic acid, which Herschel K. Mitchell, Snell, ... Mitchell, Herschel K.; Snell, Esmond E.; Williams, Roger J. (August 1941). "THE CONCENTRATION OF "FOLIC ACID"". Journal of the ... He discovered several B vitamins, including folic acid, and characterized the biochemistry of vitamin B6 (also known as ...
*  Hereditary folate malabsorption
Folic acid should not be used for the treatment of HFM. Folic acid is not a physiological folate. It binds tightly to, and may ... Santiago-Borrero, PJ; Santini R, Jr; Pérez-Santiago, E; Maldonado, N (March 1973). "Congenital isolated defect of folic acid ... Lanzkowsky, P; Erlandson, ME; Bezan, AI (October 1969). "Isolated defect of folic acid absorption associated with mental ... Urbach, J; Abrahamov, A; Grossowicz, N (January 1987). "Congenital isolated folic acid malabsorption". Archives of Disease in ...
*  Prenatal vitamins
Vitamins and minerals such as folic acid, calcium and iron are in higher concentrations while nutrients such as vitamin A are ... "Folic acid supplementation in pregnancy". "Prenatal vitamins: OK for women who aren't pregnant? - MayoClinic.com". Retrieved ... The increased dosage of folic acid or folates reflects the American Dietetic Associations position that women should consume " ... Doses of folic acid over 1mg are prescription only. The amount of non-prescription prenatal vitamins needed to achieve this ...
*  Herschel K. Mitchell
Williams and Esmond Emerson Snell in their work on vitamin B6 and folic acid. He is recognized as a co-discoverer of folic acid ... Hoffbrand, A. V.; Weir, D. G. (June 2001). "The history of folic acid". British Journal of Haematology. 113 (3): 579-589. doi: ... Mitchell, Herschel K.; Snell, Esmond E.; Williams, Roger J. (August 1941). "THE CONCENTRATION OF "FOLIC ACID"". Journal of the ... was one of many researchers interested in vitamin B6 in the early 1940s and is credited as one of the discoverers of folic acid ...
*  4-Aminobenzoic acid
Folate Synthesis (Abstract) Brown GM (1962). "The biosynthesis of folic acid. II. Inhibition by sulfonamides". J. Biol. Chem. ... 4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the number 4 carbon in the benzene ring is also known ... 4-Aminosalicylic acid Maki, T.; Takeda, K. (2000). "Benzoic Acid and Derivatives". Ullmann's Encyclopedia of Industrial ... Reduction of 4-nitrobenzoic acid Hoffman degradation of the monoamide derived from terephthalic acid. Food sources of PABA ...
*  1941 in science
Folic acid is first isolated via extraction from spinach leaves by Herschel K. Mitchell, Esmond E. Snell and Roger J. Williams ... Mitchell, H.K.; Snell, E.E.; Williams, R.J. (1941). "The concentration of "folic acid"". Journal of the American Chemical ...
*  Dihydrofolic acid
... (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to ... dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis. Click on genes, proteins and ... tetrahydrofolic acid by dihydrofolate reductase. Since tetrahydrofolate is needed to make both purines and pyrimidines, which ...
*  1945 in science
A team at American Cyanamid's Lederle Laboratories, Pearl River, New York, led by Yellapragada Subbarow, obtain folic acid in a ... Hoffbrand, A. V.; Weir, D. G. (2001). "The history of folic acid". British Journal of Haematology. 113 (3): 579-589. doi: ...