*  Grepafloxacin
... hydrochloride (trade name Raxar, Glaxo Wellcome) was an oral broad-spectrum fluoroquinolone antibacterial agent ... 2003). "Safety and tolerability of fluoroquinolones". Clin Cornerstone. Suppl 3: S29-36. PMID 14992418. Chodosh S, ...
*  Fluoroquinolone-associated disability
... ("FQAD") is an FDA formal review identification for a constellation of symptoms that have ... The U.S. FDA added a black box warning for fluoroquinolone antibiotics pertaining to peripheral nerve damage. In a ... Fluoroquinolone-Associated Disability is identified with the following Quinolone drugs: Avelox (Moxifloxacin) Cipro, Cipro XR, ... "systemic fluoroquinolone antibacterial drugs for the treatment of acute bacterial sinusitis, acute bacterial exacerbation of ...
*  Diplopia
Cataract Diabetes Drunkenness Fluoroquinolone antibiotics Graves disease Guillain-Barré syndrome Keratoconus Lyme Disease ... "Diplopia and fluoroquinolones". Ophthalmology. 116 (9): 1814-7. doi:10.1016/j.ophtha.2009.06.027. PMID 19643481. http://www. ...
*  Ofloxacin
Floxacin and other fluoroquinolones had become the most commonly prescribed class of antibiotics to adults in 2002. Nearly half ... Tendon damage may manifest during, as well as up to a year after fluoroquinolone therapy has been completed. FQs prolong the QT ... The fluoroquinolones have been shown to increase the anticoagulant effect of Acenocoumarol, Anisindione, and Dicumarol. ... The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients ...
*  Flumequine
"Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health ... "Fluoroquinolones- A Review- Dr.T R RAMANUJAM.M.D". Medindia.net. Retrieved 2010-04-04. Karbiwnyk CM, Hibbard LE, Lee RH, et al ... As such, some fluoroquinolones may cause injury to the chromosome of eukaryotic cells. There continues to be considerable ... The first-generation fluoroquinolone agents, such as flumequine, had poor distribution into the body tissues and limited ...
*  Norfloxacin
Apr 2007). "Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a ... Fluoroquinolones are not licensed by the FDA for use in children due to the risk of fatalities as well as permanent injury to ... The fluoroquinolones have also been reported as being present in the mother's milk and are passed on to the nursing child, ... Though the fluoroquinolones are sometimes used to treat typhoid and paratyphoid fever, it should be noted here that norfloxacin ...
*  Multi-drug-resistant tuberculosis
Treatment schedules for MDR-TB involving fluoroquinolones and aminoglycosides can run for 2 years, compared to the 6 months of ... MDR-TB can become resistant to the major second-line TB drug groups: fluoroquinolones (moxifloxacin, ofloxacin) and injectable ... "Fluoroquinolones for treating tuberculosis". Cochrane Database of Systematic Reviews (3): CD004795. doi:10.1002/14651858. ... rifampin and any fluoroquinolone). However, beginning with the first antibiotic treatment for TB in 1943, some strains of the ...
*  Chelation
Lomaestro BM, Bailie GR (1995). "Absorption interactions with fluoroquinolones. 1995 update". Drug Safety. 12 (5): 314-33. doi: ...
*  Isoniazid
Hans L. Riede (2009). "Fourth-generation fluoroquinolones in tuberculosis". Lancet. 373 (9670): 1148-1149. doi:10.1016/S0140- ...
*  Enoxacin
... , like other fluoroquinolones, is known to trigger seizures or lower the seizure threshold. The compound should not be ... Like other fluoroquinolones, enoxacin functions by inhibiting bacterial DNA gyrase and topoisomerase IV. The inhibition of ... Enoxacin, like other fluoroquinolones, can cause degenerative changes in weightbearing joints of young animals. The compound ... Chalumeau M, Tonnelier S, D'Athis P, Tréluyer JM, Gendrel D, Bréart G, Pons G (June 2003). "Fluoroquinolone safety in pediatric ...
*  Gemifloxacin
This warning applies to fluoroquinolones taken by mouth and injection, but does not apply to fluoroquinolones taken topically. ... Tendon damage may manifest during, as well as up to a year after fluoroquinolone therapy. The FDA ordered a black box warnings ... Some of the serious adverse effects which occur more commonly with fluoroquinolones than with other antibiotic drug classes ... Owens RC, Ambrose PG (July 2005). "Antimicrobial safety: focus on fluoroquinolones". Clin. Infect. Dis. 41 Suppl 2: S144-57. ...
*  Peripheral neuropathy
Adverse effects of fluoroquinolones: irreversible neuropathy is a serious adverse reaction of fluoroquinolone drugs ... Cohen JS (December 2001). "Peripheral neuropathy associated with fluoroquinolones" (PDF). The Annals of Pharmacotherapy. 35 (12 ... or commonly prescribed antibiotics including metronidazole and the fluoroquinolone class of antibiotics (Ciprofloxacin, ...
*  Kingella kingae
Options include aminoglycosides, macrolides and fluoroquinolones. K.Kingae can also cause infectious endocarditis, in children ... and fluoroquinolones. It shows low minimum inhibitory concentrations for penicillins, rifampicin, and azithromycin. Multiple ...
*  Clinafloxacin
... is a fluoroquinolone, structurally related to other fluoroquinolones like ciprofloxacin. It is soluble in ... Adverse effects of fluoroquinolones Grayson, ML; Crowe, SM; McCarthy, JS; Mills, J; Mouton, JW; Norrby, SR; Paterson, DL; ... Clinafloxacin's antibiotic mechanism of action, like other fluoroquinolones is derived from its activity against type II ... In the 1990s, clinafloxacin showed promise as a novel, broad-spectrum fluoroquinolone antibiotic. However, further clinical ...
*  Substance-induced psychosis
Fluoroquinolone drugs, fluoroquinolone use has been linked to serious cases of toxic psychosis that have been reported to be ... Usually such states are temporary and reversible, with fluoroquinolone-induced psychosis being a notable exception. Drugs whose ... Cohen JS (December 2001). "Peripheral Neuropathy Associated with Fluoroquinolones" (PDF). Ann Pharmacother. 35 (12): 1540-7. ... irreversible and permanent, see adverse effects of fluoroquinolones The related quinoline derivative mefloquine (Lariam) has ...
*  Ibafloxacin
... (INN) is a Fluoroquinolone antibiotic drug used in veterinary medicine. Fluoroquinolone Horspool, LJ.; van Laar, P ... fluoroquinolones with different pharmacokinetic profiles". J Vet Pharmacol Ther. 27 (3): 147-53. doi:10.1111/j.1365-2885.2004. ...
*  Legionnaires' disease
Recommended agents include fluoroquinolones, azithromycin, or doxycycline. Hospitalization is often required. About 10% of ...
*  Iron deficiency
Badal S, Her YF, Maher LJ 3rd (Sep 2015). "Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells". J Biol Chem. 290: ... interfering with iron absorption Fluoroquinolone antibiotics malabsorption syndromes inflammation where it is adaptive to limit ...
*  Antibiotic misuse
"Fluoroquinolone Resistance and Tuberculosis Treatment". USA: The New York City Department of Health and Mental Hygiene. Froom J ... The overuse of fluoroquinolone and other antibiotics fuels antibiotic resistance in bacteria, which can inhibit the treatment ... Widespread use of fluoroquinolones as a first-line antibiotic has led to decreased antibiotic sensitivity, with negative ... Gatifloxacin and moxifloxacin have no proven clinical advantages over other fluoroquinolones, macrolides, or amoxicillin. Based ...
*  Epigenetics
Fluoroquinolone antibiotics induce epigenetic changes in mammalian cells through iron chelation. This leads to epigenetic ... Badal S, Her YF, Maher LJ 3rd (Sep 2015). "Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells". J Biol Chem. 290: ...
*  Yersiniosis
Alternatives include cefotaxime, fluoroquinolones, and co-trimoxazole. "Yersiniosis". Medical Dictionary. Retrieved 2013-01-28 ...
*  Melioidosis
Single agent treatment with a fluoroquinolone (e.g., ciprofloxacin) or doxycycline for the oral maintenance phase is ... Chaowagul W, Supputtamongkul Y, Smith MD, White NJ (1997). "Oral fluoroquinolones for maintenance treatment of melioidosis". ... doxycycline monotherapy and fluoroquinolone therapy are not as effective), poor compliance with eradication therapy and ...
*  JNJ-Q2
Farrell DJ, Liverman LC, Biedenbach DJ, Jones RN (July 2011). "JNJ-Q2, a new fluoroquinolone with potent in vitro activity ... JNJ-Q2 is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and ... May 2010). "In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone". Antimicrob. Agents Chemother. ... against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains". Antimicrob. Agents Chemother. 55 ...
*  Liver support systems
"Elimination of Fluoroquinolones during Extracorporeal Albumin Dialysis (MARS)". 4th ISAD (Abstracts). Majcher-Peszynska, J; S. ...
*  Urinary tract infection
Cephalosporins, amoxicillin/clavulanic acid, or a fluoroquinolone may also be used. However, resistance to fluoroquinolones ... Fluoroquinolones are not recommended as a first treatment. The Infectious Diseases Society of America states this due to the ... Seven days of the oral fluoroquinolone ciprofloxacin is typically used in areas where the resistance rate is less than 10%. If ... The FDA recommends against the use of fluoroquinolones when other options are available due to higher risks of serious side ...