... a fibroblast cell line); rat PA adventitia fibroblasts; baby hamster kidney cells; and diverse types of vascular endothelial ... "Hydroxyeicosatetraenoic acids released through the cytochrome P-450 pathway regulate 3T6 fibroblast growth". The Journal of ...
These appear similar to fibroblasts. The stroma also contains ordinary connective tissue such as reticular fibers and collagen ...
This is secreted by fibroblasts. This is normally the thickest tunic in veins and may be thicker than the tunica media in some ...
It has been reported that the limited replicative capability of human fibroblasts observed in cell culture is far greater than ... Hayflick noticed that one of his cultures of embryonic human fibroblasts had developed an unusual appearance and that cell ... Carrel A, Ebeling AH (1921). "Age and multiplication of fibroblasts". J. Exp. Med. 34 (6): 599-606. doi:10.1084/jem.34.6.599. ... The experiment proceeded as follows: Hayflick mixed equal numbers of normal human male fibroblasts that had divided many times ...
ISBN 978-0-08-020575-5. Milo G E; Casto B C (1990). Transformation of human diploid fibroblasts. CRC Press. p. 104. ISBN 978-0- ...
Specifically preventing the formation of fibroblasts. An alternate irrigation with povidone-iodine may be used - if no contra- ...
Abercrombie, M; Heaysman, JE; Pegrum, SM (1970). "The locomotion of fibroblasts in culture. I. Movements of the leading edge". ... "Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts". Cell. 10 (3 ... is largely based on how cap formation occurs and the movement of carbon particles on the surfaces of migrating fibroblasts ...
Technique to culture fibroblasts in vitro]. Revue Française d'Études Cliniques et Biologiques. 5: 406-408. "Past ASHG Award ... In 2009, co-author Gautier claimed that the discovery was based on fibroblast tissue samples that she had prepared and noticed ...
It is expressed in lung fibroblasts. The protein is neddylated, which enhances the ubiquitination activity of SCF. Deneddylated ...
Fibroblasts are the most common cell type in connective tissue ECM, in which they synthesize, maintain, and provide a ... Wang JH, Thampatty BP, Lin JS, Im HJ (April 2007). "Mechanoregulation of gene expression in fibroblasts". Gene. 391 (1-2): 1-15 ... Elastins are synthesized by fibroblasts and smooth muscle cells. Elastins are highly insoluble, and tropoelastins are secreted ... Hadjipanayi E, Mudera V, Brown RA (February 2009). "Close dependence of fibroblast proliferation on collagen scaffold matrix ...
Fibroblasts, including periodontal fibroblasts, synthesize osteonectin. This protein is synthesized by macrophages at sites of ... It disrupts focal adhesions in fibroblasts. It also regulates the proliferation of some cells, especially endothelial cells, ... Osteonectin is expressed by a wide variety of cells, including chondrocytes, fibroblasts, platelets, endothelial cells, ... "An osteonectinlike protein in porcine periodontal ligament and its synthesis by periodontal ligament fibroblasts". Canadian ...
These include fibroblasts and endocrine cells. The symptoms of a sex-cord or stromal ovarian tumor can differ from other types ... and fibroblast growth factor 23. Use of blood test panels may help in diagnosis. The OVA1 panel includes CA-125, beta-2 ...
The fibroblasts within the granulation tissue develop into chondroblasts which also form hyaline cartilage. These two new ... Within this area, the fibroblasts replicate. Within 7-14 days, they form a loose aggregate of cells, interspersed with small ... Other sources of precursor cells are the bone marrow (when present), endosteum, small blood vessels, and fibroblasts. Primary ...
There is no increase in fibroblasts. Over time, secondary hyperkeratosis may occur, which may become verruciform. Many of these ... The serum contains circulating factors which stimulate fibroblasts to increase synthesis of glycosaminoglycans. There are ...
The FGF (Fibroblast Growth Factor) pathway stimulation leads to Smad4 phosphorylation by Erk of the canonical MAPK site located ... It is also produced by fibroblasts. The functional SMAD 4 participates in the regulation of the TGF-β signal transduction ... "TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K ...
The perineurium is composed from fibroblasts. In the peripheral nervous system, the myelin sheath of each axon in a nerve is ...
Carcinoma associated fibroblasts (CAFs) are a heterogenous group of fibroblasts whose function is pirated by cancer cells and ... fibroblast specific protein 1 (FSP-1) and fibroblast activation protein (FAP). None of these factors can be used to ... As fibroblasts, CAFs are able to rework the ECM to include more paracrine survival signals such as IGF-1 and IGF-2, thus ... As many fibroblasts are transformed into CAFs during carcinogenesis, this reduces the amount of ECM produced and the ECM that ...
Goldberg GI, Wilhelm SM, Kronberger A, Bauer EA, Grant GA, Eisen AZ (May 1986). "Human fibroblast collagenase. Complete primary ... Interstitial collagenase, also known as fibroblast collagenase, and matrix metalloproteinase-1 (MMP-1) is an enzyme that in ... "1.56 A structure of mature truncated human fibroblast collagenase". Proteins. 19 (2): 98-109. doi:10.1002/prot.340190203. PMID ...
The fibroblast growth factor (FGF) family with its prototype members FGF-1 (acidic FGF) and FGF-2 (basic FGF) consists to date ... One of the first applications of pro-angiogenic methods in humans was a German trial using fibroblast growth factor 1 (FGF-1) ... Besides FGF-1, one of the most important functions of fibroblast growth factor-2 (FGF-2 or bFGF) is the promotion of ... Blaber M, DiSalvo J, Thomas KA (February 1996). "X-ray crystal structure of human acidic fibroblast growth factor". ...
They are produced by fibroblasts and monocytes. However, the production of type I IFN-α is inhibited by another cytokine known ... Meager A, Graves H, Burke DC, Swallow DM (August 1979). "Involvement of a gene on chromosome 9 in human fibroblast interferon ... Berthold W, Tan C, Tan YH (June 1978). "Chemical modifications of tyrosyl residue(s) and action of human-fibroblast interferon ... Large amounts of human beta interferon were made by superinducing the beta interferon gene in human fibroblast cells. Cantell's ...
The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. Mutations in this gene have been shown to ... Protein dachsous homolog 1, also known as protocadherin-16 (PCDH16) or cadherin-19 (CDH19) or cadherin-25 (CDH25) or fibroblast ... This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. ... "Multiple cadherins are expressed in human fibroblasts". Biochem. Biophys. Res. Commun. 235 (2): 355-8. doi:10.1006/bbrc. ...
Interstitial fibroblasts form the tissue skeleton of the kidney. Blood vessels, nerves and lymphatic vessels run through the ... Kriz, Kaissling 2012, p. 602, Interstitial Fibroblasts. Breshears, Confer 2017, p. 622, Interstitium. A. Schumacher; M. B. ... The interstitium between the tubules contains fibroblasts, dendritic cells, macrophages and lymphocytes. Cortical interstitium ...
Kreis, Thomas E.; Birchmeier, Walter (November 1980). "Stress fiber sarcomeres of fibroblasts are contractile". Cell. 22 (2): ... "Identification of Novel Graded Polarity Actin Filament Bundles in Locomoting Heart Fibroblasts: Implications for the Generation ...
Embryonic fibroblasts that are derived from Maff−/−::Mafg−/−::Mafk−/− mice fail to activate Nrf2-dependent cytoprotective genes ...
Fibroblast are types of cells that form the extracellular matrix and collagen. Fibroblasts are the most common connective ... and provide a pathway that allows immune cells to regulate the fibroblast cells. Fibroblasts are also known as tumor mediators ... Fibroblasts play a key role when responding to tissue injury. They initiate inflammation in the presence of foreign ... Receptors found on the surface of fibroblasts regulate hematopoietic cells, start chemokine synthesis, ...
Morphogenesis begins at the time when fibroblasts are relocated to the upper part of the compact mesenchyme. Throughout this ... The development process begins with an accumulation of fibroblasts between the epidermis and dermis. Collagen fibrils begin to ... Subsequently, for both fish the fibroblasts elongate. These penetrate the compact layer of the mesenchyme, which consolidates ...
If placed in cell culture, most myoblasts will proliferate if enough fibroblast growth factor (FGF) or another growth factor is ... A transcription factor (TCF4) of connective tissue fibroblasts is involved in the regulation of myogenesis. Specifically, it ... "Connective tissue fibroblasts and Tcf4 regulate myogenesis". Development. 138 (2): 371-384. doi:10.1242/dev.057463. PMC 3005608 ...
Wang, Y. L. (1985). "Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling". The ... Abercrombie, M; Heaysman, JE; Pegrum, SM (1970). "The locomotion of fibroblasts in culture III. Movements of particles on the ... Hopkins, CR; Gibson, A; Shipman, M; Strickland, DK; Trowbridge, IS (1994). "In migrating fibroblasts, recycling receptors are ...
April 2012). "Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors". ... Cardiac fibroblasts, which represent 50% of the cells in the mammalian heart, can be reprogrammed into cardiomyocyte-like cells ... Reprogramming of cardiac fibroblasts into induced cardiomyocyte-like cells (iCMs) in situ represents a promising strategy for ... Lai et al., & Lu report the chemical method to generate MSC-like cells (iMSCs), from human primary dermal fibroblasts using six ...
Matsuyoshi N, Imamura S (1997). "Multiple cadherins are expressed in human fibroblasts". Biochem. Biophys. Res. Commun. 235 (2 ...