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*  Chronic wound
Fibroblast gene expression is different in chronic wounds than in acute wounds. Though all wounds require a certain level of ... Chronic wounds such as diabetic and venous ulcers are also caused by a failure of fibroblasts to produce adequate ECM proteins ... Some patients are treated with artificial skin substitutes that have fibroblasts and keratinocytes in a matrix of collagen to ... In addition to killing bacteria, higher oxygen content in tissues speeds growth factor production, fibroblast growth, and ...
*  3T3 cells
The 3T3 cell line has become the standard fibroblast cell line. Todaro and Green originally obtained their 3T3 cells from Swiss ... The primary mouse embryonic fibroblast cells were transferred (the "T") every 3 days (the first "3"), and inoculated at the ... This cell line was originally established from the primary mouse embryonic fibroblast cells that were cultured by the ...
*  Basic fibroblast growth factor
... , also known as bFGF, FGF2 or FGF-β, is a member of the fibroblast growth factor family. In ... Ribatti D, Vacca A, Rusnati M, Presta M (2007). "The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and ... Basic fibroblast growth factor has been shown to interact with casein kinase 2, alpha 1, RPL6 and ribosomal protein S19. ... Basic Fibroblast Growth Factor at the US National Library of Medicine Medical Subject Headings (MeSH) Human FGF2 genome ...
*  Fibroblast
Fibroblasts are the most common cells of connective tissue in animals. Fibroblasts have a branched cytoplasm surrounding an ... Fibroblasts, like the tumor-associated host fibroblasts (TAF), play a crucial role in immune regulation through TAF-derived ... Fanelli, Alex (2016). "Fibroblasts: Fibroblast Cells". Retrieved 3 December 2017. Smith, R. S.; Smith, T. J.; Blieden, T. M.; ... The life span of a fibroblast, as measured in chick embryos, is 57 ± 3 days. Fibroblasts and fibrocytes are two states of the ...
*  Dermal fibroblast
Like corneal fibroblasts, dermal fibroblast proliferation can be stimulated by the presence of fibroblast growth factor (FGF). ... For example, when a dermal fibroblast and a corneal fibroblasts are placed in the same concentrations of fibroblast growth ... Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. ... Dermal fibroblasts require far higher concentrations of fibroblast growth factor (FGF) in order to undergo cell replication. ...
*  Mouse embryonic fibroblast
Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured ... Fibroblast Embryonic stem cell Jian-ming Xu (2005). "Preparation, Culture, and Immortalization of Mouse Embryonic Fibroblasts ... "PREPARATION AND FREEZING OF MOUSE EMBRYONIC FIBROBLASTS" (PDF). LANCTÔT lab, MIT. TODARO GJ, GREEN H (1963). "Quantitative ... Amand; John A. Hanover2; Joseph Shiloach1 (2016). "A comparison of strategies for immortalizing mouse embryonic fibroblasts". J ...
*  Cancer-associated fibroblast
A cancer-associated fibroblast (CAF) (also known as tumour-associated fibroblast; carcinogenic- associated fibroblast; ... It is believed that most CAFs arise from differentiated resident fibroblast cells. The normal fibroblast cells receive a ... "Periostin Is Expressed in Pericryptal Fibroblasts and Cancer-associated Fibroblasts in the Colon". Journal of Histochemistry & ... Cancer-associated fibroblasts have been found to promote tumour growth. They do this through a number of different mechanisms, ...
*  Fibroblast-like synoviocyte
Unlike fibroblasts, fibroblast-like synoviocytes also secrete unique proteins, that are normally absent in other fibroblast ... Fibroblast-like synoviocytes are cells of mesenchymal origin that display many characteristics common with fibroblasts, such as ... Specific for fibroblast-like synoviocytes is also the expression of CD55; this protein is often used to identify this cell type ... Fibroblast-like synoviocytes (FLS) represent a specialised cell type located inside joints in the synovium. These cells play a ...
*  Fibroblast growth factor
... 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth factor 4( ... Fibroblast growth factor 6(FGF6) Fibroblast growth factor 7(FGF7) Fibroblast growth factor 8(FGF8) Fibroblast growth factor 9( ... FGF9) Fibroblast growth factor 10(FGF10) Fibroblast growth factor 11(FGF11) Fibroblast growth factor 12(FGF12) Fibroblast ... Fibroblast growth factor 15(FGF15) Fibroblast growth factor 16(FGF16) Fibroblast growth factor 17(FGF17) Fibroblast growth ...
*  Fibroblast growth factor 23
... or FGF23 is a protein that in humans is encoded by the FGF23 gene. FGF23 is a member of the ... Perwad F (2007). "Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25- ... Fukagawa M, Nii-Kono T, Kazama JJ (2005). "Role of fibroblast growth factor 23 in health and in chronic kidney disease". Curr. ... Saito H, Kusano K, Kinosaki M, Ito H, Hirata M, Segawa H, Miyamoto K, Fukushima N (2003). "Human fibroblast growth factor-23 ...
*  Fibroblast activation protein, alpha
FAP expression is seen on activated stromal fibroblasts of more than 90% of all human carcinomas. Stromal fibroblasts play an ... Fibroblast activation protein alpha is a 170 kDa melanoma membrane-bound gelatinase, protein that in humans is encoded by the ... Mathew S, Scanlan MJ, Mohan Raj BK, Murty VV, Garin-Chesa P, Old LJ, Rettig WJ, Chaganti RS (1995). "The gene for fibroblast ... Fibroblast activation protein is a homodimeric integral protein with dipeptidyl peptidase IV (DPPIV)-like fold, featuring an ...
*  Fibroblast growth factor receptor
The fibroblast growth factor receptors are, as their name implies, receptors that bind to members of the fibroblast growth ... see also Fibroblast growth factor receptor 4) (= CD334) FGFRL1 (see also Fibroblast growth factor receptor-like 1) FGFR6 Ornitz ... see also Fibroblast growth factor receptor 1) (= CD331) FGFR2 (see also Fibroblast growth factor receptor 2) (= CD332) FGFR3 ( ... These receptors bind fibroblast growth factors, members of the largest family of growth factor ligands, comprising 22 members. ...
*  Fibroblast growth factor receptor 2
FGFR2 is a receptor for fibroblast growth factor. The protein encoded by this gene is a member of the fibroblast growth factor ... Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is ... Fibroblast growth factor receptor 2 has been shown to interact with FGF1. The spliced isoforms, however differ in binding: ... Like the other members of the fibroblast growth factor receptor family, these receptors signal by binding to their ligand and ...
*  Fibroblast growth factor receptor 4
1993). "Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but ... Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as ... Fibroblast growth factor receptor 4 has been shown to interact with FGF1. GRCh38: Ensembl release 89: ENSG00000160867 - Ensembl ... Kan, M; Wu X; Wang F; McKeehan W L (May 1999). "Specificity for fibroblast growth factors determined by heparan sulfate in a ...
*  Fibroblast growth factor receptor 3
... is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as ... Hernández S, Toll A, Baselga E, Ribé A, Azua-Romeo J, Pujol RM, Real FX (July 2007). "Fibroblast growth factor receptor 3 ... This particular family member binds both acidic and basic fibroblast growth factor and plays a role in bone development and ... "Entrez Gene: FGFR3 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)". Kelleher FC, O'Sullivan H, ...
*  Fibroblast growth factor receptor 1
... (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine ... FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, which in addition to FGFR1, includes FGFR2, FGFR3, ... There are four other members of the FGFR1 gene family: FGFR2, FGFR3, FGFR4, and Fibroblast growth factor receptor-like 1 ( ... the fibroblast growth factors (FGFs), a single hydrophobic stretch which passes through the cell's surface membrane, and a ...
*  Fibroblast growth factor receptor-like 1
... is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this ... 2001). "A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1)". Biochim. Biophys. Acta. 1518 ... The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream ... Trueb B, Zhuang L, Taeschler S, Wiedemann M (2003). "Characterization of FGFRL1, a novel fibroblast growth factor (FGF) ...
*  Desmoplasia
In the reactive stroma hypothesis, tumor cells cause the proliferation of fibroblasts and subsequent secretion of collagen. The ... Myofibroblastic cells in tumors are differentiated from fibroblasts for their positive staining of smooth-muscle actin (SMA). ... These scars are hypercellular with fibroblasts, myofibroblasts, and some immune cells present. The immature scars can be ... The tumor-induced stromal change hypothesis claims that tumor cells can dedifferentiate into fibroblasts and, themselves, ...
*  Prostaglandin EP3 receptor
... mouth gingival fibroblasts; and eye (corneal endothelium and keratocytes, trabecular cells, ciliary epithelium, and ...
*  Prostaglandin EP4 receptor
... and basic fibroblast growth factor-induced osteoclast formation; bone taken from EP4(-/-) mice to re-absorb bone when induced ... and gingival fibroblasts. Standard prostanoids have the following relative efficacies in binding to and activating EP4: PGE2> ... mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts". The ...
*  15-Hydroxyeicosatetraenoic acid
... a fibroblast cell line); rat PA adventitia fibroblasts; Baby hamster kidney cells; and diverse types of vascular endothelial ... "Hydroxyeicosatetraenoic acids released through the cytochrome P-450 pathway regulate 3T6 fibroblast growth". The Journal of ...
*  Stroma of ovary
These appear similar to fibroblasts. The stroma also contains ordinary connective tissue such as reticular fibers and collagen ...
*  Hayflick limit
Hayflick and Moorhead mixed equal numbers of normal human male fibroblasts that had divided many times (cells at the 40th ... It has been speculated that the limited replicative capability of human fibroblasts in culture may have significance for human ... CS1 maint: BOT: original-url status unknown (link) Carrel A, Ebeling AH (1921). "Age and multiplication of fibroblasts". J. Exp ... He supported this hypothesis by claiming to have cultivated fibroblasts from chicken hearts and to have kept the culture ...
*  Mercury (element)
ISBN 0-08-020575-5. Milo G E; Casto B C (1990). Transformation of human diploid fibroblasts. CRC Press. p. 104. ISBN 0-8493- ...
*  CUL1
It is expressed in lung fibroblasts. The protein is neddylated, which enhances the ubiquitination activity of SCF. Deneddylated ...