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*  3T3 cells
... with the 3T3 cells secreting growth factors favourable to these kinds of cells. Todaro, GJ; Green, H (1963). "Quantitative ... The 3T3 cell line has become the standard fibroblast cell line. Todaro and Green originally obtained their 3T3 cells from Swiss ... The spontaneously immortalized cells with stable growth rate were established after 20 to 30 generations in culture, and then ... The primary mouse embryonic fibroblast cells were transferred (the "T") every 3 days (the first "3"), and inoculated at the ...
*  Basic fibroblast growth factor
... , also known as bFGF, FGF2 or FGF-β, is a member of the fibroblast growth factor family. In ... Ribatti D, Vacca A, Rusnati M, Presta M (2007). "The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and ... Angiogenesis Anxiety disorders Cytokine Fibroblast growth factor Growth factor Proteases in angiogenesis Receptor (biochemistry ... Basic fibroblast growth factor has been shown to interact with casein kinase 2, alpha 1, RPL6 and ribosomal protein S19. ...
*  Fibroblast growth factor
... 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth factor 4( ... Fibroblast growth factor 5(FGF5) Fibroblast growth factor 6(FGF6) Fibroblast growth factor 7(FGF7) Fibroblast growth factor 8( ... Fibroblast growth factor 9(FGF9) Fibroblast growth factor 10(FGF10) Fibroblast growth factor 11(FGF11) Fibroblast growth factor ... Fibroblast growth factor 13(FGF13) Fibroblast growth factor 14(FGF14) Fibroblast growth factor 15(FGF15) Fibroblast growth ...
*  Fibroblast growth factor 23
... or FGF23 is a protein that in humans is encoded by the FGF23 gene. FGF23 is a member of the ... Perwad F (2007). "Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25- ... Fukagawa M, Nii-Kono T, Kazama JJ (2005). "Role of fibroblast growth factor 23 in health and in chronic kidney disease". Curr. ... Saito H, Kusano K, Kinosaki M, Ito H, Hirata M, Segawa H, Miyamoto K, Fukushima N (2003). "Human fibroblast growth factor-23 ...
*  Fibroblast growth factor receptor
... see also Fibroblast growth factor receptor 4) (= CD334) FGFRL1 (see also Fibroblast growth factor receptor-like 1) FGFR6 Ornitz ... see also Fibroblast growth factor receptor 1) (= CD331) FGFR2 (see also Fibroblast growth factor receptor 2) (= CD332) FGFR3 ( ... The fibroblast growth factor receptors are, as their name implies, receptors that bind to members of the fibroblast growth ... These receptors bind fibroblast growth factors, members of the largest family of growth factor ligands, comprising 22 members. ...
*  Fibroblast growth factor receptor 3
... is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as ... Hernández S, Toll A, Baselga E, Ribé A, Azua-Romeo J, Pujol RM, Real FX (July 2007). "Fibroblast growth factor receptor 3 ... This particular family member binds both acidic and basic fibroblast growth factor and plays a role in bone development and ... "Entrez Gene: FGFR3 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)". Kelleher FC, O'Sullivan H, ...
*  Fibroblast growth factor receptor 4
1993). "Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but ... 1996). "Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer ... 1992). "A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor ... Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as ...
*  Fibroblast growth factor receptor 2
FGFR2 is a receptor for fibroblast growth factor. The protein encoded by this gene is a member of the fibroblast growth factor ... "Entrez Gene: FGFR2 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, ... Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is ... Fibroblast growth factor receptor 2 has been shown to interact with FGF1. The spliced isoforms, however differ in binding: ...
*  Fibroblast growth factor receptor 1
... (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine ... FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, which in addition to FGFR1, includes FGFR2, FGFR3, ... There are four other members of the FGFR1 gene family: FGFR2, FGFR3, FGFR4, and Fibroblast growth factor receptor-like 1 ( ... neoplasms with eosinophil such as those caused by Platelet-derived growth factor receptor A or platelet-derived growth factor ...
*  Fibroblast growth factor receptor-like 1
... is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this ... 2001). "A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1)". Biochim. Biophys. Acta. 1518 ... The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream ... Trueb B, Zhuang L, Taeschler S, Wiedemann M (2003). "Characterization of FGFRL1, a novel fibroblast growth factor (FGF) ...
*  Acanthosis nigricans
Increased circulating IGF may lead to keratinocyte and dermal fibroblast proliferation. Fibroblast growth factor. Hereditary ... and increased growth factor levels. Factors involved in the development of acanthosis nigricans include: Increased circulating ... Higher than normal insulin levels in the blood stream cause the growth of darkened skin over certain areas of the body. No skin ... This may include forms that are associated with tumour products and insulin-like activity, or tumour necrosis factor. An ...
*  Intracrine
Fibroblast Growth Factor -2 • Parathyroid hormone-related protein Local hormone Autocrine signalling "intracrine - definition ... Singh, VP; Baker, KM; Kumar, R (Apr 2008). "Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by ... Fiaschi-Taesch, NM; Stewart, AF (Feb 2003). "Minireview: parathyroid hormone-related protein as an intracrine factor-- ...
*  FGF4
"Differential effects of fibroblast growth factor-4, epidermal growth factor and transforming growth factor-beta1 on functional ... effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems ... Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene. The protein encoded by this gene is a ... "Entrez Gene: FGF4 fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)". Feldman B, ...
*  Secreted frizzled-related protein 1
Szebenyi G, Fallon JF (1999). "Fibroblast growth factors as multifunctional signaling factors". Int. Rev. Cytol. 185: 45-106. ... It is well known that fibroblast growth factors (FGFs) bind heparin with relatively high affinity. HSPGs have also been shown ... Growth in culture and anchorage-independent growth were inhibited in SFRP1-expressing UMRC3 cells. The growth-inhibitory ... the key factor, vascular endothelial growth factor. The regulation of the EC cytoskeleton is critical to EC spreading and ...
*  Angiogenesis
... including several growth factors. The fibroblast growth factor (FGF) family with its prototype members FGF-1 (acidic FGF) and ... by secreting various growth factors (e.g. VEGF). Growth factors such as bFGF and VEGF can induce capillary growth into the ... "Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord ... this fact distinguishes FGF-1 from other pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF), ...
*  FGF15
Fibroblast growth factor 15 is a protein in mouse encoded by the Fgf15 gene. It is a member of the fibroblast growth factor ( ... "Mouse FGF15 fibroblast growth factor 15". Jones SA (2012). "Physiology of FGF15/19". Advances in Experimental Medicine and ... McWhirter JR, Goulding M, Weiner JA, Chun J, Murre C (Sep 1997). "A novel fibroblast growth factor gene expressed in the ... Potthoff MJ, Kliewer SA, Mangelsdorf DJ (Feb 2012). "Endocrine fibroblast growth factors 15/19 and 21: from feast to famine". ...
*  FGF22
Fibroblast growth factor 22 is a protein which in humans is encoded by the FGF22 gene. The protein encoded by this gene is a ... "Entrez Gene: Fibroblast growth factor 22". This article incorporates text from the United States National Library of Medicine, ... "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family". The Journal of Biological ... member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, ...
*  FGF20
Fibroblast growth factor 20 is a protein which in humans is encoded by the FGF20 gene. The protein encoded by this gene is a ... "Entrez Gene: Fibroblast growth factor 20". This article incorporates text from the United States National Library of Medicine, ... member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, ... tumor growth and invasion. This gene was shown to be expressed in normal brain, particularly the cerebellum. The rat homolog is ...
*  FGF16
Fibroblast growth factor 16 is a protein which in humans is encoded by the FGF16 gene. The protein encoded by this gene is a ... "Entrez Gene: Fibroblast growth factor 16". This article incorporates text from the United States National Library of Medicine, ... on the fibroblast growth factor family". Biochemical and Biophysical Research Communications. 243 (1): 148-52. doi:10.1006/bbrc ... member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, ...
*  Beta trefoil fold
... and in fibroblast growth factors 1 and 2. CATH Architecture "Beta Trefoil" Murzin AG, Lesk AM, Chothia C (Jan 1992). "β-trefoil ... patterns of structure and sequence in the kunitz inhibitors interleukins-1β and 1α and fibroblast growth factors". Journal of ...
*  FGF17
Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene. The protein encoded by this gene is a ... "Entrez Gene: FGF17 fibroblast growth factor 17". Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two ... Popovici C, Conchonaud F, Birnbaum D, Roubin R (2004). "Functional phylogeny relates LET-756 to fibroblast growth factor 9". J ... activity and expression of fibroblast growth factor 17". Mech. Dev. 83 (1-2): 165-78. doi:10.1016/S0925-4773(99)00034-9. PMID ...
*  CEP57
Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic ...
*  FGF6
"Entrez Gene: FGF6 fibroblast growth factor 6". Vainikka S, Partanen J, Bellosta P, et al. (1992). "Fibroblast growth factor ... Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene. The protein encoded by this gene is a ... 1989). "Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family". Oncogene. 4 ... Popovici C, Conchonaud F, Birnbaum D, Roubin R (2004). "Functional phylogeny relates LET-756 to fibroblast growth factor 9". J ...
*  FGF19
"The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 ... Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. It functions as a hormone, regulating ... The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad ... Hyeon J, Ahn S, Lee JJ, Song DH, Park CK (2013). "Expression of fibroblast growth factor 19 is associated with recurrence and ...
*  FGF14
"Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". ... Fibroblast growth factor 14 is a protein that in humans is encoded by the FGF14 gene. The protein encoded by this gene is a ... "Entrez Gene: FGF14 fibroblast growth factor 14". Wang Q, Bardgett ME, Wong M, et al. (2002). "Ataxia and paroxysmal dyskinesia ... 2006). "Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels". J. Physiol. 569 (Pt 1): ...
*  Prostaglandin-endoperoxide synthase 2
Each subunit has three different structural domains: a short N-terminal epidermal growth factor (EGF) domain; an α-helical ... "Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts". J. Biol. Chem. 276 (37): 34975-82. ... Callan OH, So OY, Swinney DC (February 1996). "The kinetic factors that determine the affinity and selectivity for slow binding ... is a key factor regulating the activity of PGHS-2 and its response to PTGS (COX) inhibitors. PTGS2 (COX-2) is unexpressed under ...
*  FGF12
2003). "Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs". J. Biol. ... 2003). "Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B". J. Biol. Chem. 278 ( ... Schoorlemmer J, Goldfarb M (2001). "Fibroblast growth factor homologous factors are intracellular signaling proteins". Curr. ... "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". ...