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*  Urokinase
This makes urokinase an attractive drug target, and, so, inhibitors have been sought to be used as anticancer agents. However, ... Gilabert-Estelles J, Ramon LA, España F, Gilabert J, Castello R, Estelles A (2006). "Expression of the fibrinolytic components ... Urokinase is used clinically as a thrombolytic agent in the treatment of severe or massive deep venous thrombosis, pulmonary ... incompatibilities between the human and murine systems hamper clinical evaluation of these agents. Through its interaction with ...
*  PTGS1
Antiplatelet, Anticoagulant, and Fibrinolytic Drugs". In Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, ... can be further metabolized to a major class of anti-inflammatory agents, the lipoxins. In addition, PGG2 and PGH2 rearrange non ...
*  Lyme disease microbiology
Three main species (Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi s.s.) are the main causative agents of the ... New evidence suggests that B. burgdorferi may use the host's fibrinolytic system to penetrate the blood-brain barrier. ... Montgomery RR, Nathanson MH, Malawista SE (1993). "The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse ... Masuzawa T (2004). "Terrestrial distribution of the Lyme borreliosis agent Borrelia burgdorferi sensu lato in East Asia". Jpn. ...
*  Biochemical cascade
... coagulation and fibrinolytic systems and iron homeostasis Regulate iron homeostasis (acute phase independent) Via Smads /HAMP ... cascades in lymphocytes is the secretion of molecules that can suppress altered cells or eliminate pathogenic agents, through ...
*  C1-inhibitor
Lappin D, Whaley K (July 1989). "Regulation of C1-inhibitor synthesis by interferons and other agents". Behring Institute ... Although named after its complement inhibitory activity, C1-inhibitor also inhibits proteases of the fibrinolytic, clotting, ... an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema". ...
*  Tranexamic acid
In melasma - tranexamic acid is sometimes used in skin whitening as a topical agent, injected into a lesion, or taken by mouth ... Henry DA, Carless PA, Moxey AJ, O'Connell D, Stokes BJ, Fergusson DA, Ker K (January 2011). "Anti-fibrinolytic use for ...
*  Tissue plasminogen activator
Check date values in: ,date= (help) "Thrombolytic Therapy: Background, Thrombolytic Agents, Thrombolytic Therapy for Acute ... tPA and plasmin are the key enzymes of the fibrinolytic pathway in which tPA mediated plasmin generation occurs. To be specific ...
*  Emergency medical services
... paramedics effectively assume the role of out-of-hospital field agents to regional emergency physicians, with clinical decision ... "Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything ...
*  Désiré Collen
The impact of fibrinolytic therapy for ST-segment-elevation acute myocardial infarction. J Thromb Haemost 2009; 7: 14_20. ... a bacterial profibrinolytic agent with high fibrin specificity, could be a valid alternative for rt-PA in less wealthy ... culminated in the final approval of rt-PA as thrombolytic agent by the FDA on 13 November 1987. Genentech immediately started ... The controversy over whether the more expensive rt-PA was clinically superior over streptokinase as a thrombolytic agent ...
*  Hementerin
The fibrinolytic activity is inhibited by EDTA, a metal chelator agent, which removes zinc from the molecule. Hementerin is a ... 384:1333-1339(2003). [PubMed: 14515997] Abstract Rosenfeld G., Hampe O.G., Kelen E.M.A. Coagulant and fibrinolytic activity of ... animal venoms; determination of coagulant and fibrinolytic index of different species. Memórias do Instituto Butantan ;29:143- ...
*  Platelet
The fibrin is slowly dissolved by the fibrinolytic enzyme, plasmin, and the platelets are cleared by phagocytosis. In addition ... Platelets release platelet-derived growth factor (PDGF), a potent chemotactic agent; and TGF beta, which stimulates the ... Simplistically, bound and activated platelets degranulate to release platelet chemotactic agents to attract more platelets to ... and chemotactic agents. Delta granules, or dense bodies, contain ADP, calcium, serotonin, which are platelet-activating ...
*  Alveolar osteitis
There is also evidence that antifibrinolytic agents applied to the socket after the extraction may reduce the risk of dry ... The oral microbiota has been demonstrated to have fibrinolytic action in some individuals, and these persons may be predisposed ... fibrinolytic alveolitis, and is associated with increased pain and delayed healing time. Dry socket occurs in about 0.5-5% of ...
*  Utako Okamoto
The Okamotos found it was 27 times as powerful and thus a promising hemostatic agent and published their findings in the Keio ... Paul Carless (25 November 2008). "PROPOSAL FOR THE INCLUSION OF TRANEXAMIC ACID (ANTI-FIBRINOLYTIC - LYSINE ANALOGUE) IN THE ... During her lifetime she was unable to persuade obstetricians at Kobe to trial the antifibrinolytic agent, which had become a ...
*  Epoxyeicosatrienoic acid
... they are autocrine agents) or of nearby cells (i.e. they are paracrine agents). The EETs have been most studied in animal ... and/or their promotion of pro-fibrinolytic removal of blood clots. With respect to their effects on the heart, the EETs are ... Vascular contraction in the portal system is mediated by several agents: nitric oxide, carbon monoxide, prostacyclin I2, and ...
*  Aprotinin
Thrombosis, presumably from overactive inhibition of the fibrinolytic system, may occur at a higher rate, but until 2006 there ... Mahdy AM, Webster NR (2004). "Perioperative systemic haemostatic agents". British journal of anaesthesia. 93 (6): 842-58. doi: ... Tice DA, Worth Jr MH, Clauss RH, Reed GH (1964). "The inhibition of trasylol of fibrinolytic activity associated with ...