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*  Fibrinolysis
The fibrinolytic system is closely linked to control of inflammation, and plays a role in disease states associated with ... Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing ... In a process called thrombolysis (the breakdown of a thrombus), fibrinolytic drugs are used. They are given following a heart ... Thrombolysis refers to the dissolution of the thrombus due to various agents while fibrinolysis refers specifically to the ...
*  Lipodermatosclerosis
... the condition may be improved with the additional use of the fibrinolytic agent, stanozol. Fibrinolytic agents use an enzymatic ...
*  Green Cross (Japan)
Cardiovascular agents, coagulation/fibrinolytic agents, immunological agents, anti-inflammatory agents, albumin-based agents, ...
*  List of MeSH codes (D16)
... fibrin modulating agents MeSH D27.505.519.421.500 --- antifibrinolytic agents MeSH D27.505.519.421.750 --- fibrinolytic agents ... cardiotonic agents MeSH D27.505.954.411.320 --- fibrinolytic agents MeSH D27.505.954.411.455 --- natriuretic agents MeSH ... antifibrinolytic agents MeSH D27.505.954.502.270.546 --- heparin antagonists MeSH D27.505.954.502.427 --- fibrinolytic agents ... anti-allergic agents MeSH D27.505.954.122 --- anti-infective agents MeSH D27.505.954.122.085 --- anti-bacterial agents MeSH ...
*  Antifibrinolytic
Fibrinolytic agents "antifibrinolytic" at Dorland's Medical Dictionary The CRASH-2 Collaborators (2010). "Effects of tranexamic ... These lysine-like drugs interfere with the formation of the fibrinolytic enzyme plasmin from its precursor plasminogen by ...
*  Cryofibrinogenemia
... which inhibit the naturally occurring fibrinolytic agent, plasmin. 2) The blood of individuals has an increased ability of the ... Success in treating the primary disease has been reported using blood clot lysing agents such as anabolic steroids (e.g. ... Cryofiltration apheresis, a method to remove plasma agents by removing cold-induced precipitated material, may be an effective ... on the findings that some but not all individuals with the disorder have abnormally high levels of one or two of the agents, ...
*  Hementerin
The fibrinolytic activity is inhibited by EDTA, a metal chelator agent, which removes zinc from the molecule. Hementerin is a ... 384:1333-1339(2003). [PubMed: 14515997] Abstract Rosenfeld G., Hampe O.G., Kelen E.M.A. Coagulant and fibrinolytic activity of ... animal venoms; determination of coagulant and fibrinolytic index of different species. Memórias do Instituto Butantan ;29:143- ...
*  Necrosis
Chemical and toxic agents (e.g. pharmaceutical drugs, acids, bases) react with the skin leading to skin loss and eventually ... fibrinolytic or collagenases, are used to target the various components of dead tissue. In select cases, special maggot therapy ... Wounds caused by physical agents, including physical trauma and chemical burns, can be treated with antibiotics and anti- ... Chemical removal of necrotic tissue is another option in which enzymatic debriding agents, categorised as proteolytic, ...
*  Lumbrokinase
... is a fibrinolytic enzyme present in the earthworm Lumbricus bimastus. It has been investigated as an experimental ... antithrombotic agent. Hu, R. (2004). "Codon optimization, expression, and characterization of recombinant lumbrokinase in goat ...
*  Diabetic myonecrosis
Arteriosclerosis obliterans has been postulated as the cause, along with errors of the clotting and fibrinolytic pathways such ... Treatment includes supportive care with analgesics and anti-inflammatory agents. Exercise should be limited as it increases ...
*  ICD-10 Chapter III: Diseases of the blood and blood-forming organs, and certain disorders involving the immune mechanism -...
Fibrinolytic haemorrhage, acquired Fibrinolytic purpura Purpura fulminans (D66) Hereditary factor VIII deficiency Haemophilia A ... Aplastic anaemia due to other external agents (D61.3) Idiopathic aplastic anaemia (D61.8) Other specified aplastic anaemias ( ...
*  Epoxyeicosatrienoic acid
... they are autocrine agents) or of nearby cells (i.e. they are paracrine agents). The EETs have been most studied in animal ... and/or their promotion of pro-fibrinolytic removal of blood clots. With respect to their effects on the heart, the EETs are ... Vascular contraction in the portal system is mediated by several agents: nitric oxide, carbon monoxide, prostacyclin I2, and ...
*  Clopidogrel
The newer antiplatelet agent prasugrel has minimal interaction with (es)omeprazole, hence might be a better antiplatelet agent ... followed by a full year of treatment for those receiving a vascular stent A loading dose given in advance of fibrinolytic ... Clopidogrel is in the thienopyridine-class of antiplatelet agent. It works by irreversibly inhibiting a receptor called P2Y12, ... "Effect of smoking on comparative efficacy of antiplatelet agents: systematic review, meta-analysis, and indirect comparison". ...
*  Purpura
Levamisole is purportedly a common cutting agent. Decomposition of blood vessels including purpura is a symptom of acute ... 1993). "Psychogenic purpura with abnormally increased tPA dependent cutaneous fibrinolytic activity". International Journal of ... and cells Meningococcemia Cocaine use with concomitant use of the one-time chemotherapy drug and now veterinary deworming agent ...
*  Polycythemia vera
This is usually with a "cytoreductive agent" (hydroxyurea, also known as hydroxycarbamide). The tendency of some practitioners ... blood histamine levels and cutaneous fibrinolytic activity before and after water challenge". Br J Dermatol. 116 (3): 329-33. ...
*  Reperfusion therapy
These newer agents boast efficacy at least as well as rtPA with significantly easier administration. The thrombolytic agent ... Fibrinolytic Therapy Trialists' (FTT) Collaborative Group (1994). "Indications for fibrinolytic therapy in suspected acute ... Failure rates of thrombolytics can be as high as 50%. In cases of failure of the thrombolytic agent to open the infarct-related ... With tPa and related agents (reteplase and tenecteplase), heparin is needed to keep the coronary artery open. Because of the ...
*  Thrombin
... is sold under the brand name Fibrimex for use as a binding agent for meat. The thrombin in Fibrimex derives from ... Bajzar L, Morser J, Nesheim M (July 1996). "TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic ...
*  Gastão Rosenfeld
Coagulant and fibrinolytic activity of animal venoms; determination of coagulant and fibrinolytic index of different species. ... led to the development of new anti-hypertensive agents in humans, such as captopril, developed by Squibb under the name of ... Experimental defibrination and bothropase: a study on the fibrinolytic mechanism in vivo. Haemostasis. 1978;7(1):35-45. ...
*  Serpin
"Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis". BMC Plant ... "Alpha2-antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding". Blood. ... "Structure-function relationships of plasminogen activator inhibitor-1 and its potential as a therapeutic agent". Current Drug ... a synthetic heparin pentasaccharide as a new antithrombotic agent". Expert Opinion on Investigational Drugs. 11 (3): 397-407. ...
*  Platelet
The fibrin is slowly dissolved by the fibrinolytic enzyme, plasmin, and the platelets are cleared by phagocytosis. In addition ... Platelets release platelet-derived growth factor (PDGF), a potent chemotactic agent; and TGF beta, which stimulates the ... Simplistically, bound and activated platelets degranulate to release platelet chemotactic agents to attract more platelets to ... and chemotactic agents. Delta granules, or dense bodies, contain ADP, calcium, serotonin, which are platelet-activating ...
*  Urokinase
This makes urokinase an attractive drug target, and, so, inhibitors have been sought to be used as anticancer agents. However, ... Gilabert-Estelles J, Ramon LA, España F, Gilabert J, Castello R, Estelles A (2006). "Expression of the fibrinolytic components ... Urokinase is used clinically as a thrombolytic agent in the treatment of severe or massive deep venous thrombosis, pulmonary ... incompatibilities between the human and murine systems hamper clinical evaluation of these agents. Through its interaction with ...
*  Aprotinin
Thrombosis, presumably from overactive inhibition of the fibrinolytic system, may occur at a higher rate, but until 2006 there ... Mahdy AM, Webster NR (2004). "Perioperative systemic haemostatic agents". British journal of anaesthesia. 93 (6): 842-58. doi: ... Tice DA, Worth Jr MH, Clauss RH, Reed GH (1964). "The inhibition of trasylol of fibrinolytic activity associated with ...
*  Alveolar osteitis
There is also evidence that antifibrinolytic agents applied to the socket after the extraction may reduce the risk of dry ... The oral microbiota has been demonstrated to have fibrinolytic action in some individuals, and these persons may be predisposed ... fibrinolytic alveolitis, and is associated with increased pain and delayed healing time. Dry socket occurs in about 0.5-5% of ...
*  Acute-phase protein
1993). "Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: ... can contribute to the innate immune system by their ability to increase vascular permeability and act as chemotactic agents for ...
*  Utako Okamoto
The Okamotos found it was 27 times as powerful and thus a promising hemostatic agent and published their findings in the Keio ... Paul Carless (25 November 2008). "PROPOSAL FOR THE INCLUSION OF TRANEXAMIC ACID (ANTI-FIBRINOLYTIC - LYSINE ANALOGUE) IN THE ... During her lifetime she was unable to persuade obstetricians at Kobe to trial the antifibrinolytic agent, which had become a ...
*  Emergency medical services
... paramedics effectively assume the role of out-of-hospital field agents to regional emergency physicians, with clinical decision ... "Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything ...