Gatesy, J. (1997). "More DNA support for a Cetacea/Hippopotamidae clade: the blood-clotting protein gene gamma-fibrinogen". ...
Based on the calculated protein divergence figure, CIMAP1C evolves rapidly and similarly to Fibrinogen Alpha. The table below ...
This signifies that C22orf15 is evolving rapidly, but not as rapidly as fibrinogen alpha chain. There appears to be a linkage ... The slope of the trendline for C22orf15 more closely resembles the slope of the trendline for fibrinogen alpha chain, which ...
Deng, Z. J.; Liang, M.; Monteiro, M.; Toth, I.; Minchin, R. F. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 ...
... the blood-clotting protein gene gamma-fibrinogen". Molecular Biology and Evolution. 14 (5): 537-543. doi:10.1093/oxfordjournals ...
Rüegg C, Pytela R (1995). "Sequence of a human transcript expressed in T-lymphocytes and encoding a fibrinogen-like protein". ... but fibrinogen-like domains mediate ligand activity". J. Biol. Chem. 274 (42): 30196-201. doi:10.1074/jbc.274.42.30196. PMID ...
In addition, HNF-1α regulates the expression of acute phase proteins, such as fibrinogen, c-reactive protein, and interleukin 1 ... "Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters". Science. 238 (4827): 688 ...
The difference in time between the test and the 'normal' indicates an abnormality in the conversion of fibrinogen (a soluble ... If the time it takes for the plasma to clot is prolonged, a quantitative (fibrinogen deficiency) or qualitative (dysfunctional ... Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality. After ... fibrinogen) defect is present. In blood samples containing heparin, a substance derived from snake venom called batroxobin ( ...
"More DNA Support for a Cetacea/Hippopotamidae Clade: The Blood-Clotting Protein Gene y-Fibrinogen". BBC News. May 8, 2002. ...
Since fibrinogen is a rod-like protein with nodules on either end capable of binding GPIIb/IIIa, activated platelets with ... Platelet activation in turn degranulates and releases factor V and fibrinogen, potentiating the coagulation cascade. So, in ... Alpha granules contain clotting mediators such as factor V, factor VIII, fibrinogen, fibronectin, platelet-derived growth ... fibrinogen, and coagulation factors V and XIII δ granules (delta or dense granules) - containing ADP or ATP, calcium, and ...
"Fibrinogen, viscosity, and white blood cell count are major risk factors for ischemic heart disease. The Caerphilly and ...
CD11b also modulates other functions of leukocytes, e.g. oxidative burst, apoptosis, binding of fibrinogen etc. On circulating ...
8. (9) Ware, B.R; Flygare, W.H (1972). "Light scattering in mixtures of BSA, BSA dimers, and fibrinogen under the influence of ... Ware, B.R; Flygare, W.H (1972). "Light scattering in mixtures of BSA, BSA dimers, and fibrinogen under the influence of ...
... 's sequence has diverged at a quicker rate than the quickly evolving fibrinogen protein in humans. . . . . . . . ...
... anti-citrullinated fibrinogen in rheumatoid arthritis, autoimmune hepatitis. DRB1*04:05: rheumatoid arthritis, Autoimmune ... "Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen". ...
Thrombin cleaves fibrinogen into fibrin which polymerizes and crosslinks (using factor XIII) into a blood clot. The factor VIII ...
In humans treated with Oprelvekin on a daily base a twofold increase in fibrinogen levels occurred. Healthy volunteers ... fibrinogen), and inhibition of macrophageal released pro-inflammatory cytokines. However, pathologic changes, some also seen in ...
In addition, Draculin inhibits the conversion of prothrombin to thrombin, preventing fibrinogen from converting to fibrin. ...
Tissue plasminogen activator has been shown to interact with: Fibrinogen alpha chain LRP1 SERPINI1 tPA and plasmin are the key ... and plasminogen-binding sites within fibrin(ogen) alpha C-domains". Biochemistry. 40 (3): 801-8. doi:10.1021/bi001789t. PMID ...
It has evolved faster than both hemoglobin and cytochrome c, but slower than fibrinogen alpha chain. The table below reveals ... As shown in Figure 3, the c14orf119 gene has evolved moderately quickly when compared to cytochrome c, fibrinogen alpha chain, ...
He worked with his second wife, Agnes Henschen, and she used Edman's method to sequence fibrinogen. In 1977, Edman died of a ...
... has anticoagulation activity when it binds to fibrinogen, which prevents fibrinogen from converting to fibrin. ...
During this period, fibrinogen from the seminal vesicles forms a clot, securing and protecting the sperm. Just as they become ...
LigA and LigB bind extracellular matrix proteins and fibrinogen". Infection and Immunity. 75 (5): 2441-2450. doi:10.1128/IAI. ...
Graph shows divergence of UPF0488 in a given time scale compared to fibrinogen and cytochrome c. Analignment using the SDSC ... lineage of UPF0488 can be traced as distant as invertebrates with a rate of evolution greater than that of fibrinogen. ...
Molecular biology of fibrinogen and fibrin (Annals of the New York Academy of Sciences) (New York Academy of Sciences, 1983) ... and was instrumental in determining the structure of fibrinogen. Dootlittle was a member of the National Academy of Sciences ... decades of research include his role in co-developing the hydropathy index and determining the structure of fibrinogen. ...
"Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen". Blood. 102 (4 ... integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen". Blood. ...
Plasma contains a large variety of proteins including albumin, immunoglobulins, and clotting proteins such as fibrinogen. ...
By binding to prothrombin, coagulase facilitates clotting in a cell by ultimately converting fibrinogen to fibrin. Bacteria ...
... s are monomers of fibrin which are formed by the cleavage of fibrinogen by thrombin. Levels of fibrin monomers ...