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*  Factor XIII
When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked ... During circulation, this subunit binds fibrinogen. Typical concentrations of FXIII in plasma is 10 μg/ml (2A2B heterodimer), ...
*  Fibrinolysis
The ELT measures fibrinolysis by clotting the euglobulin fraction (primarily the important fibrinolytic factors fibrinogen, PAI ... and thus slow down clot formation by preventing the conversion of fibrinogen to fibrin. This effect can be seen in the thrombin ...
*  Discovery and development of direct thrombin inhibitors
Thrombin has multiple purposes, but mainly it converts soluble fibrinogen to an insoluble fibrin complex. Furthermore, it ...
*  Thrombin
In the blood coagulation pathway, thrombin acts to convert factor XI to XIa, VIII to VIIIa, V to Va, fibrinogen to fibrin, and ... Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as ... After the description of fibrinogen and fibrin, Alexander Schmidt hypothesised the existence of an enzyme that converts ... Jakubowski HV, Owen WG (July 1989). "Macromolecular specificity determinants on thrombin for fibrinogen and thrombomodulin". ...
*  Congenital hypofibrinogenemia
Fibrinogen Aguadilla is the most common mutation known to cause fibrinogen storage disease. The abbreviations in this Table are ... Individuals with fibrinogen levels of 0.5-1.0 grams/liter require fibrinogen supplementation preferably with a plasma-derived ... Zhang MH, Knisely AS, Wang NL, Gong JY, Wang JS (2016). "Fibrinogen storage disease in a Chinese boy with de novo fibrinogen ... In these instances, the un-mutated gene maintains blood fibrinogen at reduce levels but the mutated gene produces a fibrinogen ...
*  Batroxobin
The fibrinogen conversion ability of batroxobin was evaluated by a fibrinogen clotting assay and a whole blood clotting assay. ... This is probably due to the more lipophilic character of exosite 1, that binds fibrinogen more tightly. Fibrinogen is the sole ... Batroxobin is comparable to the enzyme thrombin, which is also a serine protease for fibrinogen. Fibrinogen is an important ... There was a decrease of fibrinogen. The effects were reversible. In Macaca mulatta, the fibrinogen concentration was ...
*  Thrombin time
The difference in time between the test and the 'normal' indicates an abnormality in the conversion of fibrinogen (a soluble ... If the time it takes for the plasma to clot is prolonged, a quantitative (fibrinogen deficiency) or qualitative (dysfunctional ... Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality. After ... fibrinogen) defect is present. In blood samples containing heparin, a substance derived from snake venom called batroxobin ( ...
*  Fibrinogen
The plasma fibrinogen levels (generally 50 mg/dL) detected in this disorder reflect the fibrinogen made by the normal gene. ... Endothelium cells are also reported to make what appears to be small amounts of fibrinogen but this fibrinogen has not been ... Fibrinogen functions primarily to occlude blood vessels and thereby stop excessive bleeding. However, fibrinogen's product, ... Loss or reduction in this antitrombin 1 activity due to mutations in fibrinogen genes or hypo-fibrinogen conditions can lead to ...
*  Fibrinogen beta chain
Berg K, Kierulf P (1989). "DNA polymorphisms at fibrinogen loci and plasma fibrinogen concentration". Clin. Genet. 36 (4): 229- ... Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood ... Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots ... Lord ST (2007). "Fibrinogen and fibrin: scaffold proteins in hemostasis". Curr. Opin. Hematol. 14 (3): 236-41. doi:10.1097/MOH. ...
*  Fibrinogen alpha chain
... has been shown to interact with Tissue plasminogen activator. Fibrinogen Fibrinogen gamma chain GRCh38: ... Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. The protein encoded by this gene is the alpha ... Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is the most abundant component of blood ... Doolittle RF (1984). "Fibrinogen and fibrin". Annual Review of Biochemistry. 53: 195-229. doi:10.1146/annurev.bi.53.070184. ...
*  Fibrinogen uptake test
A fibrinogen uptake test is a test that was formerly used to detect deep vein thrombosis. Radioactive labeled fibrinogen is ... Iodine 125-labeled fibrinogen scanning is a very sensitive method for detecting subclinical leg vein thrombi. Fibrinogen ... The technique is safe if fibrinogen is obtained from carefully screened donors. The limitations of the method include its ... Screening for these major thrombi may be improved by combining fibrinogen scanning with impedance plethysmography or ultrasonic ...
*  Fibrinogen gamma chain
Approximately 10% of the total plasma fibrinogen consists of γA/γ' fibrinogen, with ... Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4. The protein encoded by this gene is the gamma ... Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots ... In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor ...
*  List of fibrinogen disorders
Hereditary fibrinogen Aα-Chain amyloidosis, a form of dysfibrinogenemia in which certain fibrinogen mutations cause blood ... Fibrinogen#Fibrinogen disorders Casini A, de Moerloose P, Neerman-Arbez M (2016). "Clinical Features and Management of ... a disorder in which normal levels of fibrinogen are composed at least in part of a dysfunctional fibrinogen due to an acquired ... an inherited disorder in which normal levels of fibrinogen composed at least in part of a dysfunctional fibrinogen may cause ...
*  Fibrinogen c domain containing 1
"Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein". ... Fibrinogen C domain containing 1 (FIBCD1) is a protein that in humans is encoded by the FIBCD1 gene localized on chromosome ... Fibrinogen C domain containing 1". Retrieved 2016-03-08. Shrive, Annette K.; Moeller, Jesper B.; Burns, Ian; Paterson, Jenny M ... and a C-terminal fibrinogen-like recognition domain, otherwise known as the FReD (Shrive, et al., 2014). GRCh38: Ensembl ...
*  Vroman effect
A typical example of this occurs when fibrinogen displaces earlier adsorbed proteins on a biopolymer surface and is later ... The process is delayed in narrow spaces and on hydrophobic surfaces fibrinogen is usually not displaced. Under stagnant ... and fibrinogen in plasma at interfaces". Blood. 55 (1): 156-9. PMID 7350935. CS1 maint: Multiple names: authors list (link). ... conditions initial protein deposition takes place in the sequence: albumin; globulin; fibrinogen; fibronectin; factor XII, and ...
*  Cockatiel
Sequence analysis of intron 7 of the nuclear ?-fibrinogen gene, on the other hand, indicates that it may yet be distinct enough ... Based on DNA Sequences of The Seventh intron of Nuclear β-fibrinogen gene". Jurnal Biologi Indonesia. 7 (1): 1-11. Flegg, Jim ( ... fibrinogen gene. Doctoral work, Graduate School of Environmental Earth Science, Hokkaido University, Japan. cockatielcottage. ... inferred from DNA sequences of the seventh intron of nuclear β-fibrinogen gene. Doctoral work, Graduate School of Environmental ...
*  ITGA2B
Bennett JS (2001). "Platelet-fibrinogen interactions". Ann. N. Y. Acad. Sci. 936: 340-54. doi:10.1111/j.1749-6632.2001.tb03521. ... post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen ...
*  Helge Stormorken
... of fibrinogen and fibrin subunit chains from four different genetic dysfibrinogen variants. In: Fibrinogen-Structure. Eds. ... He described the multifaceted Stormorken syndrome, a mutations in f. VII, f. IX, Fibrinogen Oslo IV and V, all with clinical ... Stormorken, H; Brosstad, F; Seim, H (28 April 1983). "A new dysfibrinogenemia: fibrinogen Oslo IV". Thrombosis and Haemostasis ... "Characterisation of Fibrinogen Oslo IV by electrospray mass spectrometry". Thrombosis and haemostasis. 77 (5): 1040-1. PMID ...
*  CD61
Bennett JS (2001). "Platelet-fibrinogen interactions". Ann. N. Y. Acad. Sci. 936: 340-54. doi:10.1111/j.1749-6632.2001.tb03521. ... 2004). "Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease ...
*  Copper peptide GHK-Cu
Pickart noticed that liver tissue obtained from patients aged 60 to 80 years had an increased level of fibrinogen. However, ... Pilgeram, L; Pickart, L (1968). "Control of fibrinogen biosynthesis; the role of free fatty acids". J Atheroscler Res. 8: 155- ... doi:10.1016/s0368-1319(68)80089-4. Pilgeram, L (2010). "Control of fibrinogen biosynthesis; role of FFA/Albumin Ratio". ...
*  George Whipple
Measurements of blood fibrinogen. The effects of diet, hemorrhage, liver injury, and other factors on plasma fibrinogen levels ... Through his chloroform liver injury studies, Whipple demonstrated that the liver was the site of fibrinogen synthesis. While at ...
*  Tirofiban
... subunit of fibrinogen. Computation of the distance between the charged Arg and Asp sites in fibrinogen provided guidance ... Tirofiban is a synthetic, non-peptide inhibitor of the interaction of fibrinogen with the integrin glycoprotein (GP) IIb/IIIa ... Tirofiban is a small molecule inhibitor of the protein-protein interaction between fibrinogen and the platelet integrin ... "Non-Peptide Fibrinogen Receptor Antagonists. 1. Discovery and Design of Exosite Inhibitors". Journal of Medicinal Chemistry. ...
*  FCN1
The collagen-like and the fibrinogen-like domains are also found in other proteins such as tenascins, while the former is also ... 1996). "A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin". J. Biol. Chem. 271 ... 1993). "Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains". J ... "Ficolins and the fibrinogen-like domain". Immunobiology. 199 (2): 190-9. doi:10.1016/s0171-2985(98)80026-0. PMID 9777405. ...
*  FGL1
Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like ... Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the ... "Entrez Gene: FGL1 fibrinogen-like 1". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure ... FGL-1 is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved ...
*  CD11c
Ugarova TP, Yakubenko VP (2001). "Recognition of fibrinogen by leukocyte integrins". Ann. N. Y. Acad. Sci. 936 (1): 368-85. doi ...