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*  Essential fatty acid interactions
Essential fatty acid Omega-3 fatty acid Omega-6 fatty acid Ratios of Omega 3 to Omega 6 in different foods Eicosanoid ... Some of these fatty acids are 20-carbon polyunsaturated essential fatty acids - AA, EPA or DGLA. In response to a variety of ... Arachidonic acid (AA) is a 20-carbon ω-6 conditionally essential fatty acid. It sits at the head of the "arachidonic acid ... Most AA in the human body derives from dietary linoleic acid (another essential fatty acid, 18:2 ω-6), which is derived from ...
*  Fatty acid metabolism
... as blood-born fatty acids cannot cross the blood brain barrier to reach these cells. However, how the essential fatty acids, ... "Fatty Acid Biosynthesis." Trans Fatty Acids. Oxford: Blackwell Pub., 2008. 12. Print. "MetaCyc pathway: superpathway of fatty ... The fatty acids in the fats obtained from land animals tend to be saturated, whereas the fatty acids in the triglycerides of ... Fatty acids are broken down to acetyl-CoA by means of beta oxidation inside the mitochondria, whereas fatty acids are ...
*  Delta 6 desaturase
... is a desaturase enzyme that converts between types of fatty acids (termed 6 after omega-6 fatty acids), which are essential ... EctoGEM: 1.14.19.3-RXN Lee JM, Lee H, Kang S, Park WJ (January 2016). "Fatty Acid Desaturases, Polyunsaturated Fatty Acid ... and is obligatory to build the longer chain omega-3 fatty acids from other simpler fatty acids in humans[citation needed]. In ... cis-linoleic acid to gamma-linolenic acid (GLA) Palmitic acid to Sapienic acid less efficiently in humans: ALA to Stearidonic ...
*  Essential fatty acid
Those not essential are non-essential fatty acids. The term "essential fatty acid" refers to fatty acids required for ... The essential fatty acids start with the short chain polyunsaturated fatty acids (SC-PUFA): ω-3 fatty acids: α-Linolenic acid ... acid Essential fatty acid interactions Fatty acid metabolism Fatty acid synthase Nonclassic eicosanoid Oily fish Omega-3 fatty ... alpha-linolenic acid (an omega-3 fatty acid) and linoleic acid (an omega-6 fatty acid). Some other fatty acids are sometimes ...
*  List of unsaturated fatty acids
... is a pentaunsaturated fatty acid. It is one of the essential fatty acids. The recommendation of ingesting fish oil supplements ... List of saturated fatty acids Carboxylic acid List of carboxylic acids Dicarboxylic acid Simopoulos, Artemis P. (2002). "Omega‐ ... CAS Registry Number 6217-54-5. Herring acid (Herring's, Nisinic acid) is a 6,9,12,15,18,21-hexa unsaturated fatty acid with 24 ... and is a trans-2-mono-unsaturated fatty acid. C3H5 CO2H, IUPAC organization name (E)-but-2-enoic acid, trans -but-2-enoic acid ...
*  Omega-6 fatty acid
Essential fatty acid interactions Essential nutrients Linolenic acid Omega-3 fatty acid Omega-7 fatty acid Omega-9 fatty acid ... the shortest-chained omega-6 fatty acid, is one of many essential fatty acids and is categorized as an essential fatty acid ... Omega-6 fatty acids (also referred to as ω-6 fatty acids or n-6 fatty acids) are a family of pro-inflammatory and anti- ... see Essential fatty acid interactions). Some medical research suggests that excessive levels of omega-6 fatty acids from seed ...
*  Ratio of fatty acids in different foods
... acid Polyunsaturated fat Omega-3 fatty acid Omega-6 fatty acid Omega-9 fatty acid Conjugated linoleic acid Essential fatty acid ... and it is unclear whether the dietary ratio of omega-3 fatty acids and omega-6 fatty acids is important for human health. It ... 25 times more omega-6 fatty acids than omega-3 fatty acids." Monounsaturated fat For listings of particular classes of ... Simopoulos, AP (2002). "The importance of the ratio of omega-6/omega-3 essential fatty acids". Biomedicine & Pharmacotherapy. ...
*  ALOX12B
Severe dietary deficiency of polyunsaturated omega 6 fatty acids leads to the essential fatty acid deficiency syndrome that is ... Spector AA, Kim HY (January 2015). "Discovery of essential fatty acids". Journal of Lipid Research. 56 (1): 11-21. doi:10.1194/ ... "Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega- ... ALOX12B targets Linoleic acid (LA). LA is the most abundant fatty acid in the skin epidermis, being present mainly esterified ...
*  SN2 Palmitate
Prostaglandins Leukotrienes Essential Fatty Acids. pp. 139-43. Retrieved 12 January 2017. ... Palmitic acid (C16:0) is the major saturated fatty acid in human milk, accounting for 17-25% of the total fatty acids, with ... of fatty acids in human milk triglycerides involves preferential positioning of the saturated fatty acid palmitic acid (16:0) ... to release two fatty acids and one sn-2 monoglyceride into the intestinal lumen. The fatty acids configuration on the ...
*  N-Arachidonoyl dopamine
... via conjugation of arachidonic acid with dopamine". Prostaglandins, Leukotrienes and Essential Fatty Acids. 81 (4): 291-301. ... as dopamine can induce the aminolysis of the glycerol-fatty acid bonds in phospholipid chains (arachidonoyl, palmitoyl, ... "Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine". Bioorganic & Medicinal ... NADA is an endogenous arachidonic acid based lipid found in the brain of rats, with especially high concentrations in the ...
*  Seasonal effects on suicide rates
Prostaglandins Leukotrienes and Essential Fatty Acids. 71: 13-18. doi:10.1016/j.plefa.2003.12.002. CS1 maint: Uses authors ... finding that PUFA like arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid all occurred at significantly lower ... Another study focused on the association between depression, suicide, and the amount of polyunsaturated fatty acids (PUFA). ... They state that "depression is accompanied by a depletion of n-3 poly-unsaturated fatty acids". Their methodology involved ...
*  ALOX15
... and Essential Fatty Acids. 74 (4): 235-45. doi:10.1016/j.plefa.2006.01.009. PMID 16556493. Shureiqi I, Wu Y, Chen D, Yang XL, ... gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid when presented not only as free acids ... By metabolizing the ω-3 polyunsaturated fatty acids, eicosapentaenoic acid and docosahexaenoic acid, into 17-HpDHA, 17-HDHA, ... By metabolizing ω-3 polyunsaturated fatty acids, eicosapentaenoic acid and docosahexaenoic acid, into lipoxins and resolvins, ...
*  Cysteinyl leukotriene receptor 1
... and Essential Fatty Acids. 105: 1-8. doi:10.1016/j.plefa.2015.12.004. PMID 26869085. Kar M, Altıntoprak N, Muluk NB, Ulusoy S, ... ALOX5 metabolizes arachidonic acid to the 5,6-epoxide precursor, LTA4, which is then acted on by LTC4 synthase which attaches ... The CysLTR1 gene product variant, 300G/S (i.e. amino acid glycine replaces serine at the 300 position of the CysLTR1 protein), ... The major CysLTs viz., LTC4, LTD4, and LTE4, are metabolites of arachidonic acid made by the 5-lipoxygenase enzyme, ALOX5, ...
*  Docosahexaenoic acid
"Omega-3 Fatty Acids: An Essential Contribution". Retrieved 12 June 2015. Denomme J, Stark KD, Holub BJ (2005). "Directly ... DHA-clozapine List of omega-3 fatty acids Polyunsaturated fatty acids Guesnet P, Alessandri JM (2011). "Docosahexaenoic acid ( ... DHA is the most abundant omega-3 fatty acid in the brain and retina. DHA comprises 40% of the polyunsaturated fatty acids ( ... Meharban Singh (March 2005). "Essential Fatty Acids, DHA and the Human Brain from the Indian Journal of Pediatrics, Volume 72 ...
*  Ketone bodies
"Omega-3 fatty acids, energy substrates, and brain function during aging". Prostaglandins, Leukotrienes and Essential Fatty ... are also unable to uptake fatty acids because fatty acids cannot pass the blood-brain barrier. In all other tissues the fatty ... Unlike free fatty acids, ketone bodies can cross the blood-brain barrier and are therefore available as fuel for the cells of ... Fatty acids are very high energy fuels, and are taken up by all metabolizing cells which have mitochondria. This is because ...
*  Food pyramid (nutrition)
"Omega-3 fatty acids and bipolar disorder: A review". Prostaglandins, Leukotrienes and Essential Fatty Acids. 60 (5-6): 329-337 ... Burr, George O.; Burr, Mildred M. (1930-04-01). "On The Nature And Rôle Of The Fatty Acids Essential In Nutrition". The Journal ... Arts, Michael T; Ackman, Robert G; Holub, Bruce J (2001). ""Essential fatty acids" in aquatic ecosystems: A crucial link ... Toft, Ingrid (1995-12-15). "Effects of n-3 Polyunsaturated Fatty Acids on Glucose Homeostasis and Blood Pressure in Essential ...
*  PTGS1
... and Essential Fatty Acids. 73 (3-4): 141-62. doi:10.1016/j.plefa.2005.05.002. PMID 16005201. Wlodawer P, Samuelsson B (August ... While metabolizing arachidonic acid primarily to PGG2, COX-1 also converts this fatty acid to small amounts of a racemic ... The cyclooxygenase activity incorporates two oxygen molecules into arachidonic acid or alternate polyunsaturated fatty acid ... such as linoleic acid and eicosapentaenoic acid. Metabolism of arachidonic acid forms a labile intermediate peroxide, PGG2, ...
*  Stearoyl-CoA desaturase-1
... and Essential Fatty Acids. 68 (2): 113-121. doi:10.1016/s0952-3278(02)00261-2. ISSN 0952-3278. PMID 12538075. Flowers, Matthew ... This is how the monounsaturated fatty acid oleic acid is produced from the saturated fatty acid stearic acid. A series of redox ... This phenomenon depends on increased expression of fatty acid biosynthetic enzymes that produce required fatty acids in large ... The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic ...
*  ALOX15B
... and Essential Fatty Acids. 74 (4): 235-45. doi:10.1016/j.plefa.2006.01.009. PMID 16556493. Subbarayan V, Krieg P, Hsi LC, Kim J ... converting this fatty acid to the S stereoisomer of 13-hydroperoxyoctadecadienoic acid which is likewise rapidly reduced to the ... 15-LOX-2 has 38-39% amino acid sequence identity to human 15-LOX-1 and 12-lipoxygenase and 44% amino acid sequence identity to ... 15-LOX-2 converts arachidonic acid almost exclusively to the S stereoisomer of 15-Hydroperoxyicosatetraenoic acid which is ...
*  5-lipoxygenase-activating protein
Peters-Golden M, Brock TG (2003). "5-lipoxygenase and FLAP". Prostaglandins, Leukotrienes, and Essential Fatty Acids. 69 (2-3 ... and Essential Fatty Acids. 81 (1): 9-15. doi:10.1016/j.plefa.2009.05.022. PMID 19524426. Zintzaras E, Rodopoulou P, ... 5-hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic acid, and specialized pro-resolving mediators of the lipoxin and ... FLAP functions as a membrane anchor for 5-lipooxygenase and as an amine acid-bind protein. How FLAP activates 5-lipooxygenase ...
*  Lipoxin
Levy BD (2005). "Lipoxins and lipoxin analogs in asthma". Prostaglandins, Leukotrienes, and Essential Fatty Acids. 73 (3-4): ... Lipoxins are derived enzymatically from arachidonic acid, an ω-6 fatty acid. Structurally, they are defined as arachidonic acid ... which are metabolites of the omega 3 fatty acids, eicosapentaenoic acid or docosahexaenoic acid, as well as a range of ... Leukotrienes and Essential Fatty Acids. 73 (3-4): 163-177. doi:10.1016/j.plefa.2005.05.003. PMID 16125378. Li Q, Tian Y, Wang ...
*  Pirinixic acid
These data demonstrate that genes induced by PPARα activation via free fatty acids from ATGL-dependent reactions are essential ... PPAR activation occurs with free fatty acid binding, or fatty acid derivative ligands that have been broken down via the ... stimulates free fatty acid oxidation by increasing mitochondrial free fatty acid uptake and oxidation via two enzymes: ... Leukotrienes and Essential Fatty Acids. 60: 339-343. doi:10.1016/s0952-3278(99)80009-x. Fruchard, J.; Duriez, P.; Steals, B. ( ...
*  FABP7
... and Essential Fatty Acids. 57 (1): 77-84. doi:10.1016/S0952-3278(97)90496-8. PMID 9250612. Xu LZ, Sánchez R, Sali A, Heintz N ( ... The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of ... cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty ... Pu L, Igbavboa U, Wood WG, Roths JB, Kier AB, Spener F, Schroeder F (Aug 1999). "Expression of fatty acid binding proteins is ...
*  Neurodevelopmental disorder
Leukotrienes and Essential Fatty Acids. 63 (1-2): 1-9. doi:10.1054/plef.2000.0184. PMID 10970706. Nordham, Elizabeth A; ... Richardson, A.J.; Ross, M.A. (July 2000). "Fatty acid metabolism in neurodevelopmental disorder: a new perspective on ... "Folic Acid - March of Dimes". "Folate (Folacin, Folic Acid)". "Folic scid: topic home". Centers for Disease Control and ... The most common nutritional cause of neural tube defects is folic acid deficiency in the mother, a B vitamin usually found in ...
*  Medical Hypotheses
Stein, John (2004). "David Horrobin (1939-2003): A memoir". Prostaglandins, Leukotrienes and Essential Fatty Acids. 70 (4): 339 ... Leukotrienes and Essential Fatty Acids, another journal founded by Horrobin. "Journal Citation Reports". Clarivate Analytics. ...
*  List of food additives
Citranaxanthin - color Citric acid - food acid Citric acid esters of mono- and diglycerides of fatty acids - emulsifier Citrus ... vegetable gum Montanic acid esters - humectant Mullein (Verbascum thapsus) Mustard - Mustard oil (essential oil), containing a ... Common food acids include vinegar, citric acid, tartaric acid, malic acid, fumaric acid, and lactic acid. Acidity regulators ... Acetic acid - acidity regulator Acetic acid esters of mono- and diglycerides of fatty acids - emulsifier Acetylated distarch ...
*  OXGR1
... and Essential Fatty Acids. 91 (3): 105-10. doi:10.1016/j.plefa.2014.02.006. PMC 4127125 . PMID 24768603. Shirasaki H, Kanaizumi ... The projected amino acid sequence of the protein encoded by the GPR80 gene bore similarities to a purinergic receptor, P2Y1, ... He W, Miao FJ, Lin DC, Schwandner RT, Wang Z, Gao J, Chen JL, Tian H, Ling L (May 2004). "Citric acid cycle intermediates as ... The Gene has recently been nominated as a receptor not only for 2-oxogluterate (see alpha-Ketoglutaric acid) but also for the ...