It is activated by thrombin to factor XIIIa. Factor XIIIa is an enzyme of the blood coagulation system that crosslinks fibrin. ... Factor XIIIa (dimer of two active A units) crosslinks fibrins within the clot by forming isopeptide bonds between various ... Factor XIII is a transglutaminase that circulates in human blood as a heterotetramer of two A and two B subunits. Factor XIII ... Factor XIII Deficiency is also known as Laki-Lorand factor, after Kalman Laki and Laszlo Lorand, the scientists who first ...
... factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl- ... "Hierarchies in the binding of human factor XIII, factor XIIIa, and endothelial cell transglutaminase to human plasma fibrinogen ... Grundmann U, Amann E, Zettlmeissl G, Küpper HA (1986). "Characterization of cDNA coding for human factor XIIIa". Proc. Natl. ... Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a ...
Derrick EK, Barker JN, Khan A, Price ML, Macdonald DM (1993). "The tissue distribution of factor XIIIa positive cells". ... Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and ... Other immune factors found in the testis include the enzyme inducible nitric oxide synthase (iNOS), and its product nitric ... Further research is required to define the functional roles of these immune factors in the testis. Mumps is a viral disease ...
... they express Factor XIIIa, CD1c, and Class II Human leukocyte antigens. A subset of cells differentiates into Langerhans cells ... and growth factors such as GM-CSF, TNF and IL-4. The various categories of histiocytes are distinguishable by their morphology ...
"Human inter-α-inhibitor is a substrate for factor XIIIa and tissue transglutaminase". Biochimica et Biophysica Acta (BBA) - ...
Am J Pathol 1989;135:793-800 Cerio R, Spaull J, Oliver GF, Wilson Jones E: A study of factor XIIIa and MAC 387 immunolabeling ... Scand J Dent 1994; 102:290-4. Hedin CA, Gerner L, Larsson Å: The retrocuspid papilla and factor XIIIa: an epidemiologic and ... Scand J Dent 1994; 102:290-4. Hedin CA, Gerner L, Larsson Å: The retrocuspid papilla and factor XIIIa: an epidemiologic and ... Scand J Dent 1994; 102:290-4. Hedin CA, Gerner L, Larsson Å: The retrocuspid papilla and factor XIIIa: an epidemiologic and ...
1997). "Hierarchies in the binding of human factor XIII, factor XIIIa, and endothelial cell transglutaminase to human plasma ... factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl- ... "Hierarchies in the binding of human factor XIII, factor XIIIa, and endothelial cell transglutaminase to human plasma fibrinogen ... Coagulation factor XIII B chain is a protein that in humans is encoded by the F13B gene. This gene encodes coagulation factor ...
Comparison with factor XIIIa and CD34". British Journal of Dermatology. 157 (2): 319-24. doi:10.1111/j.1365-2133.2007.08033.x. ... Risk factors for developing multiple dermatofibromas include lupus, HIV, blood cancer and some medicines that weaken immunity. ...
Immunohistochemical stains for CD34, S-100 protein, factor XIIIa, and estrogen and progesterone receptors were performed on ... However, the resulting fusion protein is processed into a mature platelet-derived growth factor which is a potent growth factor ... As with many other stromal neoplasms, DFSPs appear to express low levels of hormone receptors, which may be one factor that ... Fibroblasts contain the receptor for this growth factor. Thus the cell "thinks" it is producing a structural protein, but it ...
... factor XIIIa (plasma transglutaminase; activated form of fibrin-stabilizing factor) promotes fibrin cross-linking, and ... If a coagulation factor is part of the contact activation or tissue factor pathway, a deficiency of that factor will affect ... Tissue factor, FV and FVIII are glycoproteins, and Factor XIII is a transglutaminase. The coagulation factors circulate as ... Assignment of numerals ceased in 1963 after the naming of Factor XIII. The names Fletcher Factor and Fitzgerald Factor were ...
Thrombin also activates factor XIII from the human body to factor XIIIa, which then cross-links the fibrin monomers to form a ... Formulations from different manufacturers may also contain aprotinin, fibronectin, plasminogen, and factor XIII. Factors that ... KEGG drug: Factor XIII with fibrinogen. Accessed 2020-07-09. "Evicel". U.S. Food and Drug Administration (FDA). 5 June 2017. ...
In the final common pathway fibrin is cross-linked by activated clotting factor XIII (termed factor XIIIa) to form mature gel- ... The dysfibrinogenemias consist of three types of fibrinogen disorders in which a critical blood clotting factor, fibrinogen, ... fibrinogen concentration is the rate-limiting factor in blood clot formation and along with blood platelets is critical to this ...
... and blood clotting factor XIIIa-specific peptide ligands. He has published over 30 peer-reviewed papers, book chapters, and ... "Identification of Motifs in the Fasciclin Domains of the Transforming Growth Factor-beta -induced Matrix Protein beta ig-h3 ... "The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells". Gene. 366 (1): 145-151. ...
... by factor XIII ('plasma protransglutaminase') or XIIIa to form 'gamma-dimers'. The image at the left is a crystal structure of ... Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action ... Factor XIII completes the cross-linking of fibrin so that it hardens and contracts. The cross-linked fibrin forms a mesh atop ...
... which are factor XIIIa-negative) in the interstitium and around the adnexa of dermis of skin, as well as cells in soft tissue ... Kees UR, Ford J (February 1999). "Synergistic action of stem-cell factor and interleukin-7 in a human immature T-cell line". ... as a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of ... "CD34 expression by murine hematopoietic stem cells mobilized by granulocyte colony-stimulating factor". Blood. 96 (5): 1989- ...
... factor XIIIa-positive cells in the mid and reticular dermis.: 613 Skin lesion James, William; Berger, Timothy; Elston, Dirk ( ...
... factor xiiia MeSH D08.811.913.050.276 - 5-aminolevulinate synthetase MeSH D08.811.913.050.294 - arylalkylamine n- ... factor viia MeSH D08.811.277.656.300.760.310 - factor ixa MeSH D08.811.277.656.300.760.315 - factor xa MeSH D08.811.277.656. ... complement factor b MeSH D08.811.277.656.300.760.200 - complement factor d MeSH D08.811.277.656.300.760.210 - complement factor ... 300.760.320 - factor xia MeSH D08.811.277.656.300.760.324 - factor xiia MeSH D08.811.277.656.300.760.353 - furin MeSH D08.811. ...
LCS will also stain positive for CD-68, CD-68R, CD-21, CD-35, S-100, CD1a, lysozyme, HLA-DR, CD4, fascin, Factor XIIIa, and ...
The individual fibrin strands then polymerize and are crosslinked with other fibrin strands by blood factor XIIIa to form an ... Fibrinogen (factor I) is a glycoprotein complex, produced in the liver, that circulates in the blood of all vertebrates. During ...
... factor xa MeSH D23.119.425.320 - factor xia MeSH D23.119.450.324 - factor xiia MeSH D23.119.475.500 - factor xiiia MeSH D23.119 ... factor va MeSH D23.119.325.300 - factor viia MeSH D23.119.350.300 - factor viiia MeSH D23.119.375.310 - factor ixa MeSH D23.119 ... fibroblast growth factor 1 MeSH D23.348.383.120 - fibroblast growth factor 2 MeSH D23.348.383.130 - fibroblast growth factor 3 ... fibroblast growth factor 5 MeSH D23.348.383.160 - fibroblast growth factor 6 MeSH D23.348.383.170 - fibroblast growth factor 7 ...
Factor XIIIa is a transglutaminase that catalyzes the formation of covalent bonds between lysine and glutamine residues in ... activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is ... Factor Xa with factor V as a cofactor leads to cleavage of the Gla and two Kringle domains (forming together a fragment called ... Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). The activity of factor ...
F11 Factor XII deficiency; 234000; F12 Factor XIIIA deficiency; 613225; F13A1 Factor XIIIB deficiency; 613235; F13B Failure of ... GLA Factor V and factor VIII, combined deficiency of; 227300; MCFD2 Factor V deficiency; 227400; F5 Factor XI deficiency, ... C1NH Complement factor H deficiency; 609814; HF1 Complement factor I deficiency; 610984; CFI Complex I, mitochondrial ... LCAT Fletcher factor deficiency; 612423; KLKB1 Focal cortical dysplasia, Taylor balloon cell type; 607341; TSC1 Focal dermal ...
... factor xia MeSH D12.776.124.125.450.324 - factor xiia MeSH D12.776.124.125.475.500 - factor xiiia MeSH D12.776.124.125.500.265 ... factor viiia MeSH D12.776.124.125.375.310 - factor ixa MeSH D12.776.124.125.400.315 - factor xa MeSH D12.776.124.125.425.320 - ... complement factor h MeSH D12.776.124.486.274.920.325.210 - complement factor i MeSH D12.776.124.486.274.920.662 - complement ... complement factor d MeSH D12.776.124.486.274.900 - complement factor b MeSH D12.776.124.486.274.920 - complement inactivator ...
Type XIIa has a long grip similar to that of type XIIIa. The XIIa was originally a part of the XIIIa classification, but ... Oakeshott's 13 sword types are distinguished by several factors, the most important of which characterize its blade: cross ... Very few examples of the parent type XIII exist, while more examples of the subtype XIIIa survive. A depiction of two-handed ... Subtype XIIa (originally classified as XIIIa) consists of the longer, more massive greatswords that appear in the mid-13th ...
... "a dominating factor in the world's development", both for national defense and economic benefit. Winged Defense sold only 4,500 ... MIT Program XIII-A Centennial. MIT. Retrieved December 11, 2010. "Historic Markers - General Mitchell Field WI221". Milwaukee ...