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*  Coagulation factor II receptor
Proteinase-activated receptor 1 (PAR1) also known as Protease-activated receptor 1 or coagulation factor II (thrombin) receptor ... "Entrez Gene: F2R coagulation factor II (thrombin) receptor". "José RJ, Williams AE, Chambers RC (Feb 2014). "Proteinase- ... 271 (42): 26320-8. doi:10.1074/jbc.271.42.26320. PMID 8824285. Shapiro MJ, Trejo J, Zeng D, Coughlin SR (Dec 1996). "Role of ... 105 (8): 3178-84. doi:10.1182/blood-2004-10-3985. PMID 15626732. José RJ, Williams AE, Mercer PF, Sulikowski MG, Brown JS, ...
*  Factor X
... is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as ... Factor Xa is the activated form of the coagulation factor thrombokinase, known eponymously as Stuart-Prower factor. Factor X is ... The result is a Factor VIIa/TF complex which catalyzes the activation of Factor X and Factor IX. Factor Xa formed on the ... Factor XIa activates free Factor IX on the surface of activated platelets. The activated Factor IXa with Factor VIIIa forms the ...
*  Factor VIII
... (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII ... Factor VIII was first characterized in 1984 by scientists at Genentech. The gene for factor VIII is located on the X chromosome ... Copper is a required cofactor for factor VIII and copper deficiency is known to decrease levels of factor VIII. There is a ... "NIH: F8 - coagulation factor VIII". National Institutes of Health. "Entrez Gene: F8 coagulation factor VIII, procoagulant ...
*  Factor V Leiden
... (rs6025) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which ... In the normal person, factor V functions as a cofactor to allow factor Xa to activate prothrombin, resulting in the enzyme ... is a natural anticoagulant that acts to limit the extent of clotting by cleaving and degrading factor V. Factor V Leiden is an ... which normally inhibits the pro-clotting activity of factor V) is not able to bind normally to Factor V, leading to a ...
*  Haemophilia
Factor VIII is used in haemophilia A and factor IX in haemophilia B. Factor replacement can be either isolated from human blood ... the Y-chromosome in the male has no gene for factors VIII or IX. If the genes responsible for production of factor VIII or ... such as porcine factor VIII.[citation needed] If a person becomes refractory to replacement coagulation factor as a result of ... which occurs due to not enough clotting factor VIII, and haemophilia B, which occurs due to not enough clotting factor IX. They ...
*  Discovery and development of direct thrombin inhibitors
Furthermore, it activates factors V, VIII and XI, all by cleaving the sequences GlyGlyGlyValArg-GlyPro and PhePheSerAlaArg- ... When a blood vessel ruptures or gets injured, factor VII comes into contact with tissue factors which starts a process called ... Most of those drugs are in the class of direct factor Xa inhibitors, but there is one DTI called AZD0837, which is a follow-up ... Thrombin also activates factor XIII that stabilizes the fibrin complex and therefore the clot and it stimulates platelets, ...
*  Discovery and development of direct Xa inhibitors
Factors IIa, Xa, VIIa, IXa and XIa are all proteolytic enzymes that have a specific role in the coagulation cascade. Factor Xa ... Inhibition of factor Xa leads to antithrombotic effects by decreasing the amount of thrombin. Directly targeting factor Xa is ... Today there are three factor Xa inhibitors marketed: rivaroxaban, apixaban and edoxaban. Factor Xa was identified as a ... It is defined as the formation of insoluble fibrin by activated coagulation factors, specifically thrombin. These factors ...
*  Thrombin
In the blood coagulation pathway, thrombin acts to convert factor XI to XIa, VIII to VIIIa, V to Va, fibrinogen to fibrin, and ... activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is ... Lenting PJ, van Mourik JA, Mertens K (December 1998). "The life cycle of coagulation factor VIII in view of its structure and ... Factor Xa with factor V as a cofactor leads to cleavage of the Gla and two Kringle domains (forming together a fragment called ...
*  Haemophilia B
Factor IX becomes active eventually in coagulation by cofactor factor VIII (specifically IXa). Platelets provide a binding site ... which has a longer half life than factor VIII and as such factor IX can be transfused less frequently. Blood transfusions may ... Factor IX when activated activates factor X which helps fibrinogen to fibrin conversion. ... which allows for neatly packaged bottles of factor IX concentrates. With the rise of factor IX concentrates it became easier ...
*  Factor VIII (medication)
Factor VIII is a medication used to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII ... Factor VIII was first identified in the 1940s and became available as a medication in the 1960s. Recombinant factor VIII was ... A purified factor VIII concentrate is made from human blood plasma. A recombinant version is also available. People may develop ... "Coagulation Factor VIII, Human - Drugs.com". www.drugs.com. Archived from the original on 9 January 2017. Retrieved 8 January ...
*  Surf Factor 8
... is the eighth album released by surf music band The Surfin' Lungs, released in 2016 on Redondo Records. All bar ...
*  Factor 8: The Arkansas Prison Blood Scandal
Factor VIII, died as a result. Factor 8 uses in-depth interviews and key documents as well as never-before-seen footage, to ... Factor 8: The Arkansas Prison Blood Scandal was screened at Slamdance 2005 and at the American Film Institute's Los Angeles ... Factor 8: The Arkansas Prison Blood Scandal is a feature-length documentary by Arkansas filmmaker and investigative journalist ... The British premiere of Factor 8 was held on September 29, 2006, as part of the 14th Raindance Film Festival in Piccadilly ...
*  Multiple Epidermal Growth Factor-like Domains 8
Nuclear respiratory factor 1 RXR heterodimer binding sites GATA binding factors Nuclear receptor subfamily 2 factors Octamer ... binding protein EGR/nerve growth factor induced protein C & related factors Neuron-restrictive silencer factor MEGF8 is ... GC-Box factors SP1/GC Estrogen response elements KRAB domain zinc finger protein 57 Neuron-specific olfactory factor (2 sites) ... Ccaat/Enhancer Binding Protein Vertebrate TATA binding protein factor CCAAT binding factors Activator-, mediator- and TBP- ...
*  X Factor (Denmark season 8)
X Factor is a Danish television music competition to find new singing talent. The eighth season premiered on 2 January 2015 and ... http://www.bt.dk/x-factor/remee-derfor-skal-jeg-ikke-vaere-x-factor-dommer-igen https://www.dr.dk/DRPresse/Artikler/2014/08/11/ ... www.dr.dk/event/xfactor/x-factor-optager-i-koebenhavn-meld-dig-som-publikum Politiken: Børneeksperter: Fjern alle under 18 år ... Performed of Peter Bjørnskov and X Factor 2015-finalists) On 25 March, two days before the final, Bente Boserup, leader of ...
*  X Factor (Ukraine series 8)
X Factor is a Ukranian television music competition to find new singing talent and part of a British franchise The X Factor. ... The eight series began on 2 September 2017 and will conclude on 30 December 2017. The judging panel consists of Oleg Vinnik, ...
*  The X Factor (Australia season 8)
"The X Factor - 2016". "Iggy Azalea confirms she will replace Dannii Minogue on The X Factor". Mail Online. Retrieved 2016-06-20 ... https://au.tv.yahoo.com/x-factor/clips/33034149/the-x-factor-preview-sunday-30th-october/ https://au.tv.yahoo.com/x-factor/ ... "The X Factor - 2016". Knox, David (16 September 2016). "Returning: The X Factor 2016". tvtonight.com.au. Australia: Daily ... au.tv.yahoo.com/x-factor/33256424/get-ready-for-special-guests-worthy-of-an-x-factor-grand-final/#page1 "Monday 3 October 2016 ...
*  The X Factor (UK series 8)
"Who's coming back to The X Factor? - The X Factor - Story". Xfactor.itv.com. Retrieved 11 November 2011. "The X Factor voting ... The X Factor' - X Factor News - Reality TV". Digital Spy. 4 December 2011. Retrieved 10 November 2012. "The X Factor BIG twist ... X Factor News - Media". Digital Spy. Retrieved 11 November 2011. "'X Factor' cancels text voting for final - X Factor News - ... programmes.stv.tv/the-x-factor/news/286815-michael-bubl-brings-christmas-present-to-x-factor-final/ "X Factor Final: lady in ...
*  Fear Factor: Khatron Ke Khiladi 8
The eighth season of Fear Factor: Khatron Ke Khiladi, an Indian reality and stunt television series premiered on 22 July 2017 ... "KHATRON KE KHILADI 8: Shiny Doshi OUT of the show?". 3 June 2017. "Khatron Ke Khiladi: Shiny Doshi eliminated; Manveer Gurjar ... "Khatron Ke Khiladi 8 final contestants list: Nia Sharma, Manveer Gurjar, Hina Khan to fight their fears this season". Retrieved ... "Khatron Ke Khiladi 8 6 August 2017 Review: Nia Sharma Gets Eliminated From Rohit Shetty's Show". 7 August 2017. "Khatron Ke ...
*  List of The X Factor finalists (UK series 8)
"The X Factor - The Risk". itv.com. Retrieved 11 November 2011. "STV: Scots band The Risk want X Factor group to change name". ... "The X Factor - Misha B". Retrieved 7 July 2012. "Sami Brookes booted off X Factor - Showbiz - Evening Standard". Standard.co.uk ... "X Factor: Craig Colton teases new 'indie' album". Retrieved 20 July 2012. "X Factor's Craig is working with Robbie Williams!". ... X Factor' Rhythmix to change name following charity pressure - X Factor News - TV". Digital Spy. 26 October 2011. Retrieved 11 ...
*  List of The X Factor finalists (Australia season 8)
Prior to The X Factor, he worked at a car repair shop. Woder had three kids with his fiance. He performed his original song " ... Prior to entering The X Factor, she was a barista. Taylor met her Australian husband when he was stationed in the military in ... Knowles auditioned for The X Factor singing "Pillowtalk" by Zayn Malik. His mentor Guy Sebastian selected him as one of his top ... The eighth season of The X Factor Australia premiered on the Seven Network on 3 October 2016. The judging panel consisted of ...
*  Bio Products Laboratory
During the 1970's and 1980's it became apparent that Factor VIII products produced at the BPL site (and other products from ... Applications using this early discover were limited due to naturally low concentrations of this anti-haemophilic factor in ... self-published source] "Companies". Factor 8 Campaign UK. "Final Report: Chapter 19 - Production of Blood Products - Facilities ... which was treatable with blood protein called Factor IX. An agreement was reached between the Government, MRC and the Lister ...
*  Contaminated haemophilia blood products
"Making Factor VIII". Factor 8 Campaign UK. Templin, Chris. "Transcript from SCARBOROUGH COUNTRY of MSNBC from 8-22-2003 about ... In re Factor VIII or IX Concentrate Blood Products Litigation, Appeals of Roy G. Spece, Jr., Rose Marie Ibanez, and Mull & Mull ... Factor VIII is a protein that helps the clotting of blood, which haemophiliacs, due to the genetic nature of their condition, ... Ryan White, an American youth who was infected with HIV from using tainted blood from the plasma product Factor VIII Bad Blood ...
*  Hassan Joharchi
Blue Saga of Heroes White Nights Factor 8 She Was an Angle Kimia Distances "Hasan Joharchi passed away". ISNA (in Persian). 3 ... "Factor 8 on IRIB1". jamejamonline. Retrieved 3 February 2017. "Kimia absorbed watchers". Parsnews. Retrieved 3 February 2017. " ...
*  Armour and Company
Armour's Factor VIII product "Factorate" is widely reported as infecting thousands of Haemophiliacs worldwide with HIV during ... "Companies". Factor 8 Campaign UK. Information, Reed Business (17 July 1986). "New Scientist". Reed Business Information. "Firm ...
*  United Kingdom tainted blood scandal
Factor products such as Recombinant Factor VIII continue to be widely used. Factor products work by replacing the missing ... There are currently 1,555 confirmed deaths in the UK of people who were killed by the clotting agents Factor VIII & Factor IX ... but it did import large quantities of Factor VIII given to haemophiliacs (as described in the documentary Factor 8: The ... The infections were principally caused by the plasma derived product known as Factor VIII, a medicinal product that was sourced ...
*  Jaap Schreurs
His relatives consulted eight experts from prominent Dutch museums, art magazines, and auctioneering firms. These unanimously ... style has been visibly influenced by three factors, namely Loss of eyesight: ophthalmologist dr. Philippe Lanthony from the ... Werf, Judith van der (2010), 'Judith in gesprek met Jaap Schreurs'. Mensen, Magazine IKON, 3, 2010, p. 8. website dedicated to ... Keita, Fatou (1993), 'Jaap Schreurs ou l'éloquence de la protestation silencieuse'. In: New Horizon, nr.8, p.28-29. Laansma, ...
*  Certified Information Technology Professional
Determine critical success factors viii. Determine appropriate measurements for a given IT strategy ix. Align IT strategic plan ... Assess on-going training and end-user support viii. Analyze asset life cycle, including routine technology planning and IT ... pages 4-8 To be awarded the CITP Credential, a CPA must accumulate 100 total points. Total points will be earned based on ...