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*  Etoposide
... is in the topoisomerase inhibitor family of medication. It is believed to work by damaging DNA. Etoposide was ... It is used in form of its salt etoposide phosphate. Etoposide was first synthesized in 1966 and U.S. Food and Drug ... which ironically can be treated with etoposide itself) When given with warfarin, it may cause bleeding. Etoposide forms a ... Etoposide, sold under the brand name Etopophos among others, is a chemotherapy medication used for the treatments of a number ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: E: Etoposide
High doses of etoposide along with other chemotherapy drugs have been used with autologous bone marrow transplant for ... High doses of etoposide along with other chemotherapy drugs have been used with autologous bone marrow transplant for ... MedlinePlus: Etoposide Oral and Injection Information provided about precautions, side effects, proper storage, brand names, ...
*  Genistein
etoposide and doxorubicin. In high doses it was found to be strongly toxic to normal cells. This effect may be responsible for ...
*  ADE (chemotherapy)
Etoposide - a topoisomerase inhibitor. Fludarabine and cytosine are less effective than standard ADE chemotherapy in high-risk ...
*  Drug discovery
Etoposide · Teniposide); 3a. Anthracyclines (Aclarubicin · Daunorubicin · Doxorubicin · Epirubicin · Idarubicin · Amrubicin · ...
*  Epipodophyllotoxin
These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II. Podophyllotoxin Takimoto ...
*  EI24
Etoposide-induced protein 2.4 homolog is a protein that in humans is encoded by the EI24 gene. This gene has higher expression ... "Entrez Gene: EI24 etoposide induced 2.4 mRNA". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap ...
*  Hartmann F. Stähelin
A few years later, in November 1983, etoposide was approved by the U.S. Food and Drug Administration. Etoposide is still ... etoposide, Vepesid, discovered on October 21, 1966), which remains very clinically successful. Teniposide and etoposide were ... there are an astonishing number of coincidences between etoposide and cyclosporine. The first coincidence was that etoposide ... After a landmark clinical comparative analysis by F. Muggia and M. Rozencweig, etoposide and teniposide were licensed to ...
*  Chemotherapy
Podophyllotoxin is used to produce two other drugs with different mechanisms of action: etoposide and teniposide. Topoisomerase ... ifosfamide and etoposide. Permanent thinning or hair loss can result from some standard chemotherapy regimens. Chemotherapy ... These agents include etoposide, doxorubicin, mitoxantrone and teniposide. The second group, catalytic inhibitors, are drugs ...
*  Quinine 3-monooxygenase
Relling MV, Evans R, Dass C, Desiderio DM, Nemec J (1992). "Human cytochrome P450 metabolism of teniposide and etoposide". J. ... Zhao XJ, Kawashiro T, Ishizaki T (1998). "Mutual inhibition between quinine and etoposide by human liver microsomes. Evidence ...
*  Grapefruit-drug interactions
Etoposide interferes with grapefruit, orange, and apple juices. Fexofenadine (Allegra) Fluvoxamine (Luvox, Faverin, Fevarin and ... Bitter oranges (such as the Seville oranges often used in marmalade) can interfere with drugs including etoposide, a ... Apple juice has been implicated in interfering with etoposide, a chemotherapy drug, and cyclosporine, taken by transplant ...
*  Endodermal sinus tumor
Treatment with cisplatin, etoposide, and bleomycin has been described. Before modern chemotherapy, this type of neoplasm was ...
*  Lung cancer
In SCLC, cisplatin and etoposide are most commonly used. Combinations with carboplatin, gemcitabine, paclitaxel, vinorelbine, ... etoposide or vinorelbine. Platinum-based drugs and combinations that include platinum therapy may lead to a higher risk of ...
*  Small-cell carcinoma
First line treatment is usually with cisplatin and etoposide. In Japan, the first line treatment is shifting to irinotecan and ... In cases of LS-SCLC, combination chemotherapy (often including cyclophosphamide, cisplatinum, doxorubicin, etoposide, ...
*  Epithelioid sarcoma
Etoposide, vincristine, dactinomycin, and cyclophosphamide have also traditionally been given. Newer chemotherapies, such as ...
*  Schedule H
Ethacridine Lactate Ethambutol Hydrochloride Ethamsylate Ethinylestradiol Ethionamide Etomidate Etoposide Cap. & Inj. ...
*  Diazirine
Examples include: The synthesis of a diazirine containing analog of etoposide, a widely used cancer drug targeting ... "A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II". Bioorganic & Medicinal Chemistry. 18 (2): 830- ... topoisomerase II, which holds promise for the identification of the etoposide binding site. The discovery that caprolactam-type ...
*  Lipid signaling
Chemotherapeutic agents such as daunorubicin and etoposide enhance the de novo synthesis of ceramide in studies done on ... 2000). "Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis". J. Biol. Chem. ...
*  PAFAH1B2
"Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876-84. doi: ...
*  SARNP
"Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment". Proteomics. 4 (4): ...
*  SPTLC1
2000). "Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis". J. Biol. Chem. ...
*  CLIC2
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ...
*  Fungal isolate
Fungi can synthesize podophyllotoxin and camptothecin, precursors to etoposide, teniposide, topotecan, and irinotecan. Lentinan ...
*  TOP2B
"Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis". The Journal of ...
*  TOP2A
"Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis". J. Biol. Chem. United ...