"Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers" (PDF). Science. 303 (5662): 1352-5. ...
Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe". J. Biol. Chem. 274 (18): 12702-9. doi: ...
"Complexity and differential expression of carbohydrate epitopes associated with L-selectin recognition of high endothelial ...
"Mast cell alpha-chymase reduces IgE recognition of birch pollen profilin by cleaving antibody-binding epitopes". J. Immunol. ...
This implies that there must be two epitopes on the protein (one to capture the protein and one to detect the protein) for ... The target protein is detected either by direct labeling or a secondary labeled antibody against a different epitope on the ... This problem is overcome with RPMAs as the samples can be denatured, revealing any concealed epitopes. The biggest limitation ... and often the labeling destroys the epitope to which the antibody binds. This problem is overcome by RPMAs as sample need not ...
Activating and blocking antibodies mostly bind to conformational epitopes, whereas neutral antibodies bind to linear epitopes. ... Most antibodies produced are directed to conformational epitopes of the immunogenic carboxyl-terminal region of the TPO protein ... although antibodies to linear epitopes have been seen. Anti-TPO antibodies are the most common anti-thyroid autoantibody, ...
Friedman RS, Spies AG, Kalos M (April 2004). "Identification of naturally processed CD8 T cell epitopes from prostein, a ... March 2004). "Identification of an HLA-A*0201-restricted T-cell epitope derived from the prostate cancer-associated protein ...
"Display of the viral epitopes on Lactococcus lactis: a model for food grade vaccine against EV71". Biotechnology Research ...
This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the ... 2002). "Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes". J. Immunol. 167 ( ...
This could lead to the development of an antidote that reacts with the same epitope located on these different toxins. ... Several preclinical studies have identified epitopes that are present in many different toxins from the T. serrulatus scorpion ... August 2005). "Localization of epitopes in the toxins of Tityus serrulatus scorpions and neutralizing potential of therapeutic ... studies was to ascertain the neutralizing potential of these antivenoms by examining their reactivity with different epitopes ...
Her group has developed a computer algorithm to choose epitopes to combine into a mosaic molecule for the mosaic antigens. In ... In addition, the database focuses on the small regions (called epitopes) within the virus that can be recognized by antibodies ... epitopes). In 2009, Korber described the process: "I create sort of little Frankenstein proteins that look and feel like HIV ... and evaluates the evidence for the strength of each epitope in eliciting immune responses. There is also data on the ...
A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed ... 2009). "Development of a novel peptide microarray for large-scale epitope mapping of food allergens". Journal of Allergy and ... 2011). "Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals". Journal of ... 2012). "Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa ...
"The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activation". Mol ...
"Mast cell alpha-chymase reduces IgE recognition of birch pollen profilin by cleaving antibody-binding epitopes". J. Immunol. ...
... epitopes ('Tregitopes') were discovered in 2008 and consist of linear sequences of amino acids contained ... Su Y, Rossi R, De Groot AS, Scott DW (August 2013). "Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo ... January 2013). "In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance ... September 2013). "Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes". Molecular Therapy ...
These oligosaccharides mimic the carbohydrate epitopes present in longer repeat units found in bacterial capsular ...
April 2013). "A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to ... June 2019). "Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against ... generated rabbit monoclonal antibodies targeting rare and poorly immunogenic epitopes of mesothelin, including the C terminus ... "New high affinity monoclonal antibodies recognize non-overlapping epitopes on mesothelin for monitoring and treating ...
"Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer ...
"Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease - a comparative CSF study", ... "Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease - a comparative CSF study". ...
October 2020). "Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients". Cellular & ... November 2020). "Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity". Science. ... June 2020). "Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients". ... December 2020). "Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent population". Emerging ...
Second group of TI antigens consists mainly of highly repetitive surface structures (epitopes) of encapsulated bacteria. They ...
Lewis epitopes are important in determining blood groups, and allow the generation of an immune response if we detect foreign ... O-glycans near the membrane maintain the elongated structure and a terminal sLex epitope is necessary for interactions with the ... O-glycan structures, and especially the terminal Lewis epitopes, are important in allowing tumor cells to invade new tissues ... Addition of fucose sugars by fucosyltransferases forms Lewis epitopes and the scaffold for blood group determinants. Addition ...
By treating with antibodies binding multiple epitopes, the treatment is still effective even if the virus mutates and one of ... Monoclonal antibodies, on the other hand, all bind the same epitope with high specificity. They can be produced with the ... mAbs against infections stop working when virus mutates the epitope that is targeted by the mAbs or multiple strain are ... Polyclonal antibodies are collection of antibodies that target the same pathogen but bind to different epitopes. Polyclonal ...
She carried out the molecular identification of the HY genes and the peptide epitopes they encode. Simpson's work has led to an ...
The random sequences are not selected for containing known epitopes, or antibody binding sites, of pathogens. When a sample of ... the 17-mers are long enough that there are multiple potential epitopes on each individual peptide. Antibodies are present in ...
CTP-37 consists of two epitopes and those who responded to both epitopes demonstrated prolonged survival, with 65 weeks, ... Two epitopes can be found in CTP-37 one of which is dominant and can elicit anti-bodies against hCG. By employing this ideology ... The modulation of the earlier formulation was done to force the immune system to act against multiple epitopes, with the aim of ... Also, Gemcitabine did not affect the patients ability to have an immune response to Avicine's epitopes. Data from a phase Ib ...
"Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes". Journal of ... In individuals who express a protective HLA B*27 allele, the first mutation that occurs in the Gag epitope KK10 is at position ... The extent and frequency to which an epitope will be targeted by a particular HLA allele differs from person-to-person. ... Moreover, as a consequence of immunodominance, an individual's CTL response is limited to a few epitopes of a specific HLA ...
"Venom and viral expression products of the endoparasitic wasp Campoletis sonorensis share epitopes and related sequences". ...
2006). "A molecular approach to the identification of cytotoxic T-lymphocyte epitopes with Equine Herpes-1". Journal of General ...
"Immunocytochemical detection of lignin-related epitopes in cell walls in bryophytes and the charalean alga Nitella". Plant ...