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*  Hepatocyte growth factor
Epidermal growth factor Insulin-like growth factor 1 Epithelial-mesenchymal transition Madin-Darby Canine Kidney Cells GRCh38: ... Hepatocyte growth factor (HGF) (or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is ... Hepatocyte growth factor at the US National Library of Medicine Medical Subject Headings (MeSH) Hepatocyte growth factor on the ... Nakamura T (1992). "Structure and function of hepatocyte growth factor". Progress in Growth Factor Research. 3 (1): 67-85. doi: ...
*  Epidermal growth factor
... has been shown to interact with epidermal growth factor receptor. Recombinant human epidermal growth ... Epidermal growth factor can be found in urine, saliva, milk, and plasma. The production of epidermal growth factor has been ... Supply of Epidermal Growth Factor EGF at the Human Protein Reference Database. Epidermal growth factor at the US National ... Epidermal growth factor (EGF) stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is a 6-kDa ...
*  Epidermal growth factor receptor
"Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor". Biochemistry. ... "Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor". Growth ... including epidermal growth factor and transforming growth factor α (TGFα) ErbB2 has no known direct activating ligand, and may ... can prevent the growth of EGFR-expressing tumours and improve the patient's condition. Epidermal growth factor receptor (EGFR) ...
*  Multiple Epidermal Growth Factor-like Domains 8
... growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain ... Epidermal Growth Factor Domain: a short peptide with a distinctive motif of six cysteines, which is found in many different ... "Multiple Epidermal Growth Factor-like Domains 8 Gene". MEGF8 Gene Card. Weizmann Institute of Science in Israel. Retrieved 4 ... Megf8 also known as Multiple Epidermal Growth Factor-like Domains 8, is a protein coding gene that encodes a single pass ...
*  Stanley Cohen (biochemist)
Louis in the 1950s, Cohen isolated nerve growth factor and then went on to discover epidermal growth factor. He continued his ... Prize in Physiology or Medicine in 1986 for the isolation of nerve growth factor and the discovery of epidermal growth factor. ... Cohen, Stanley (1993). "Epidermal Growth Factor" (PDF). In Tore Frängsmyr and Jan Lindsten (Eds.). Nobel Lectures, Physiology ... Carpenter, G.; Cohen, S. (1979). "Epidermal Growth Factor". Annual Review of Biochemistry. 48: 193-216. doi:10.1146/annurev.bi. ...
*  Keratinocyte
Epidermal growth factor. Transforming growth factor alpha. Cholera toxin. Within the epidermis keratinocytes are associated ... The roles of transforming growth factor-alpha and epidermal growth factor". Cell. 50 (7): 1131-7. doi:10.1016/0092-8674(87) ... Rheinwald, JG; Green, H (1977). "Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes". ... "Epidermal repair results from activation of follicular and epidermal progenitor keratinocytes mediated by a growth factor ...
*  Saliva
Herbst RS (2004). "Review of epidermal growth factor receptor biology". International Journal of Radiation Oncology, Biology, ... Epidermal growth factor (EGF) Various enzymes; there are three major enzymes found in saliva: α-amylase (EC3.2.1.1), or ptyalin ... Researchers at the University of Florida at Gainesville have discovered a protein called nerve growth factor (NGF) in the ... before it binds to intrinsic factor There is much debate about the amount of saliva that is produced in a healthy person per ...
*  Ubiquitin-interacting motif
Vertebrate hepatocyte growth factor-regulated tyrosine kinase substrate (HRS). Mammalian epidermal growth factor receptor ... Mammalian epidermal growth factor receptor substrate EPS15R. Drosophila melanogaster (Fruit fly) liquid facets (lqf), an epsin ... substrate 15 (EPS15), which is involved in cell growth regulation. ...
*  Tooth decay
CS1 maint: Multiple names: authors list (link) Herbst RS (2004). "Review of epidermal growth factor receptor biology". ... Growth factors, especially TGF-β, are thought to initiate the production of reparative dentin by fibroblasts and mesenchymal ... Possible contributing factors that have been investigated include systemic factors such as high levels of dioxins or ... However, the risk factors and stages of development are similar. Initially, it may appear as a small chalky area (smooth ...
*  Pathophysiology of heart failure
October 2003). "Aldosterone stimulates epidermal growth factor receptor expression". J. Biol. Chem. 278 (44): 43060-66. doi: ... and also by epidermal growth factor (EGF), which is a target of the signaling pathway activated by aldosterone Reduced ... Many of these remodelling effects seem to be mediated by transforming growth factor beta (TGF-beta), which is a common ...
*  Stomach
Epidermal growth factor (EGF) results in cellular proliferation, differentiation, and survival. EGF is a low-molecular-weight ... Herbst RS (2004). "Review of epidermal growth factor receptor biology". International Journal of Radiation Oncology, Biology, ... and gastric ATPase ATP4A and gastric intrinsic factor GIF, expressed in parietal cells. A series of radiographs can be used to ... The parietal cells of the human stomach are responsible for producing intrinsic factor, which is necessary for the absorption ...
*  John Mendelsohn (doctor)
... growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth ... "Targeting the epidermal growth factor receptor for cancer therapy". Journal of Clinical Oncology. Retrieved March 2, 2011. " ... "Epidermal growth factor receptor family and chemosensitization". Journal of the National Cancer Institute. Retrieved March 2, ... Antibody 225 (commercially known as Cetuximab, or Erbitux) against the receptor for epidermal growth factor was approved by the ...
*  Tesevatinib
... including epidermal growth factor receptor (EGFR; ERBB1), epidermal growth factor receptor 2 (HER2; ERBB2), vascular ... June 15, 2007). "Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647". Clin. Cancer ... June 15, 2007). "Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647". Clinical ... endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). The drug activity was initially studied in non-small cell ...
*  STS-73
Crystallization of the Epidermal Growth Factor (EGF); Structure of the Membrane-Embedded Protein Complex Photosystem I; ... Spacelab Glovebox Facility experiments included the Zeolite Crystal Growth Glovebox, Protein Crystal Growth Glovebox and the ... the Crystal Growth by Liquid-Liquid Diffusion, the Commercial Protein Crystal Growth experiment; the Advanced Protein ... the Vapor Transport Crystal Growth of Mercury Cadmium Tellurida in Microgravity experiment; the Zeolite Crystal Growth Furnace ...
*  ErbB
... and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using ... "Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α". ... "Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor ... There are 11 growth factors that activate ErbB receptors. The ability ('+') or inability ('-') of each growth factor to ...
*  Cell wall associated kinase
Sampoli Benitez, Benedetta A; Komives, Elizabeth A (2000). "Disulfide bond plasticity in epidermal growth factor". Proteins: ... bound to the cell wall and contains a series of epidermal growth factor repeats. WAKs are found in various plants and crops ... all of which contain at least two epidermal growth factor (EGF). Of all these isoforms, WAK1 and WAK2 are most ubiquitous and ... All of the isomers of WAK proteins have epidermal growth factor (EGF) like repeats located at the amino-terminal side. Six ...
*  Anti-aging supplements
Epidermal growth factor, a 53 amino acid protein. In various research, epidermal growth factor has been shown to reduce fine ... "Controlled-release of epidermal growth factor from cationized gelatin hydrogel enhances corneal epithelial wound healing". ... abnormal growths), and poor texture. Despite great demand, many such products and treatments have not been proven to give ...
*  CBL (gene)
Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR (September 2002). "Sprouty2 attenuates epidermal growth factor ... "Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and ... "cbl-b inhibits epidermal growth factor receptor signaling". Oncogene. 18 (10): 1855-66. doi:10.1038/sj.onc.1202499. PMID ... Sehat B, Andersson S, Girnita L, Larsson O (July 2008). "Identification of c-Cbl as a new ligase for insulin-like growth factor ...
*  Calcium-binding EGF domain
Appella E, Weber IT, Blasi F (April 1988). "Structure and function of epidermal growth factor-like regions in proteins". FEBS ... Davis CG (May 1990). "The many faces of epidermal growth factor repeats". New Biol. 2 (5): 410-9. PMID 2288911. Blomquist MC, ... Doolittle RF, Feng DF, Johnson MS (1984). "Computer-based characterization of epidermal growth factor precursor". Nature. 307 ( ... "How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2- ...
*  Immunohistochemistry
Among the overexpressed targets are members of the epidermal growth factor receptor (EGFR) family, transmembrane proteins with ... Harari, P M (December 2004). "Epidermal growth factor receptor inhibition strategies in oncology". Endocrine-Related Cancer. ... September 2006). "Assessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their ...
*  CBLB (gene)
CBLB has been shown to interact with: CRKL, Epidermal growth factor receptor, Grb2, NEDD4, PIK3R1, and SH3KBP1. GRCh38: Ensembl ... 2001). "Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex". J. Biol. Chem. 276 ... 1999). "cbl-b inhibits epidermal growth factor receptor signaling". Oncogene. 18 (10): 1855-66. doi:10.1038/sj.onc.1202499. ... "cbl-b inhibits epidermal growth factor receptor signaling". Oncogene. 18 (10): 1855-66. doi:10.1038/sj.onc.1202499. PMID ...
*  GRB2
Colony stimulating factor 1 receptor, DCTN1, DNM1, Dock180, Dystroglycan, EPH receptor A2, ETV6, Epidermal growth factor ... Grb2 is best known for its ability to link the epidermal growth factor receptor tyrosine kinase to the activation of Ras and ... Ettenberg SA, Keane MM, Nau MM, Frankel M, Wang LM, Pierce JH, Lipkowitz S (Mar 1999). "cbl-b inhibits epidermal growth factor ... The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and ...
*  LDL receptor
Beyond this, exons 2-6 code the ligand binding region; 7-14 code the epidermal growth factor (EGF) domain; 15 codes the ... There are three "growth factor" repeats; A, B and C. A and B are closely linked while C is separated by the YWTD repeat region ...
*  CBLC
2002). "Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK ... 1999). "Cbl-b inhibits epidermal growth factor receptor signaling". Oncogene. 18 (10): 1855-66. doi:10.1038/sj.onc.1202499. ... CBLC has been shown to interact with FYN and Epidermal growth factor receptor. GRCh38: Ensembl release 89: ENSG00000142273 - ... 2002). "C-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination". J ...
*  Menadione
It was reported, that menadione topical lotion reduces epidermal growth factor receptor inhibitor-related side effects by the ... Tianhong Li & Roman Perez-Soler (2009). "Skin toxicities associated with epidermal growth factor receptor inhibitors". Targeted ...
*  Prostaglandin-endoperoxide synthase 2
Each subunit has three different structural domains: a short N-terminal epidermal growth factor (EGF) domain; an α-helical ... Callan OH, So OY, Swinney DC (February 1996). "The kinetic factors that determine the affinity and selectivity for slow binding ... is a key factor regulating the activity of PGHS-2 and its response to PTGS (COX) inhibitors. PTGS2 (COX-2) is unexpressed under ...
*  Lipid raft
Epidermal growth factor (EGF) binds to EGF receptor, also known as HER-1 or ErbB1, to initiate transmembrane signaling.Lipid ... Mineo, Chieko; Gill, Gordon N.; Anderson, Richard G.W. (1999). "Regulated migration of epidermal growth factor receptor from ... Roepstorff, Kirstine; Thomsen, Peter; Sandvig, Kirsten; van Deurs, Deurs (2002). "Sequestration of epidermal growth factor ... Miljan, Erik A; Bremer, Eric G. (2002). "Regulation of growth factor receptors by gangliosides". Sci STKE. 160: RE15. doi: ...