In 2001, Entrez bookshelf was released and in 2003, the Entrez Gene database was developed. "Definition of 'entrez'". Collins ... Entrez can efficiently retrieve related sequences, structures, and references. The Entrez system can provide views of gene and ... "Home - Gene - NCBI". Entrez Utilities. National Center for Biotechnology Information (US). 2010. The E-utility Web Service ( ... The Entrez front page provides, by default, access to the global query. All databases indexed by Entrez can be searched via a ...
"Entrez". Entrez gene. Retrieved 19 June 2015. de Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, Wittinghofer A, Bos ... Human RAPGEF3 gene is present on chromosome 12 (12q13.11: 47,734,367-47,771,041). Out of the many predicted transcript variants ... identified cAMP-GEFI and cAMP-GEFII as novel genes enriched in brain using a differential display protocol and by screening ... "Ensembl". H. Human RAPGEF3 gene. Retrieved 19 June 2015. Rehmann H, Das J, Knipscheer P, Wittinghofer A, Bos JL (February 2006 ...
cDNA cloning, gene localization, and expression". The Journal of Biological Chemistry. 272 (6): 3628-3634. doi:10.1074/jbc. ... "MTR 5-methyltetrahydrofolate-homocysteine methyltransferase (Homo sapiens)". Entrez. 19 May 2009. Retrieved 24 May 2009. Li YN ... Mutations in the MTR gene have been identified as the underlying cause of methylcobalamin deficiency complementation group G, ... Several cblG-associated polymorphisms in the MTR gene have been identified. 2756D→G (Asp919Gly) 3804C→T (Pro1137Leu) Δ2926A- ...
"KSR2". Entrez Gene. Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli JP, et al. (November 2013). " ... The KSR2 gene (also called "The fat gene")[citation needed] is Kinase suppressor of ras 2 it is a protein that in humans is ... KSR2 mutation effects in humans by obesity and because KSR2 gene reduces the ERK signaling and it reduces glucose and fatty ... Portal: Biology (Articles with short description, Short description matches Wikidata, Genes on human chromosome 12, All ...
"PDE4A phosphodiesterase 4A, cAMP-specific ( Homo sapiens )". Entrez Gene. 2012-03-04. Retrieved 2012-04-02. Hansen RT, Conti M ... cAMP-specific 3',5'-cyclic phosphodiesterase 4A is an enzyme that in humans is encoded by the PDE4A gene. The protein encoded ... Milatovich A, Bolger G, Michaeli T, Francke U (Mar 1994). "Chromosome localizations of genes for five cAMP-specific ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 19, Wikipedia articles ...
"H19: imprinted maternally expressed transcript (non-protein coding) (Homo sapiens)". Entrez Gene. National Center for ... This gene also has a role in the formation of some cancers and in the regulation of gene expression. . The H19 gene is ... H19 gene transcription has also been shown to be activated by the presence of the E2F1 transcription factor. The H19 gene codes ... Gene therapy trials utilizing the H19 promoter to drive the expression of cytotoxic genes are currently being tested on mice. A ...
"LGR5 leucine-rich repeat-containing G protein-coupled receptor 5". Entrez Gene. "LGR5 leucine-rich repeat containing G protein- ... The Human LGR5 gene is 144,810 bases long and located at chromosome 12 at position 12q22-q23. Both human, rat and mouse ... This implies that LGR5 is not an oncogene but a tumor suppressor gene, and that its main role is delimiting stem cell expansion ... Hsu SY, Liang SG, Hsueh AJ (December 1998). "Characterization of two LGR genes homologous to gonadotropin and thyrotropin ...
"Entrez Gene". Southgate L, Machado RD, Snape KM, Primeau M, Dafou D, Ruddy DM, Branney PA, Fisher M, Lee GJ, Simpson MA, He Y, ... The Rho GTPase activating protein 31 is encoded in humans by the ARHGAP31 gene. It is a Cdc42/Rac1 GTPase regulator. ARHGAP31 ... 1999). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from ... Human ARHGAP31 genome location and ARHGAP31 gene details page in the UCSC Genome Browser. Bandyopadhyay S, Chiang CY, ...
"BRP44 brain protein 44". Entrez Gene. "mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family". UniProt. "Pyruvate ... MPC1 gene). The symptoms associated with mutations in the MPC2 gene include early-onset neurological problems, normal lactate/ ... March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, All stub articles, ...
"SRF serum response factor". Entrez Gene. National Center for Biotechnology Information, National Institutes of Health. ... is a downstream gene target for Tbx genes". J. Biol. Chem. 280 (12): 11816-28. doi:10.1074/jbc.M412408200. PMID 15591049. Li S ... This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts ... Interaction of SRF with other proteins such as myocardin or Elk-1 may enhance or suppress expression of genes important for ...
Gene. 168 (2): 267-270. doi:10.1016/0378-1119(95)00741-5. PMID 8654957. "DNASE1L1 deoxyribonuclease I-like 1". Entrez Gene. U.S ... Just like the DNase I enzyme produced by the DNase I gene, the DNase1L1 (DNaseX) enzyme produced by the DNase1L1 (DNaseX) gene ... The DNase1L1/DNaseX gene was discovered in the early 1990s by Johannes F. Coy as a member of the Molecular Genome Analysis ... This gene encodes a member of the deoxyribonuclease family and the protein and DNA shows high sequence similarity to lysosomal ...
"Entrez Gene: MUTYH mutY homolog (E. coli)". GeneCard for MUTYH Slupska MM, Baikalov C, Luther WM, Chiang JH, Wei YF, Miller JH ... "MUTYH". Entrez Gene.[permanent dead link] Online Mendelian Inheritance in Man (OMIM): Familial adenomatous polyposis 2; FAP2 - ... the mutations for the MUTYH gene is biallelic. Mutations in this gene affect the ability of cells to correct mistakes made ... The protein structure of the MUTYH gene has its N-terminal on the 5' and the C-terminal on the 3'. Within the N-terminal, there ...
Entrez Gene. FAS Fas (TNF receptor superfamily, member 6). https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=gene& ... This gene is member 6 of the TNF-receptor superfamily (TNFRSF6). The Fas receptor contains a death domain and has been shown to ... As a result of the mutation in the Fas receptor gene, there is no recognition of Fas by Fas receptor, leading to a primitive ... There are several inherited gene mutations that have been identified to cause lymphoproliferative disorders; however, there are ...
"PER3". Entrez Gene. NCBI. 2017. Retrieved 12 Apr 2017. "Per3 Gene". GeneCards. Weizmann Institute of Science. Retrieved April ... "Entrez Gene: PER3 period homolog 3 (Human)". Pendergast JS, Niswender KD, Yamazaki S (2012). "Tissue-specific function of ... While the Per3 gene is a paralog to the PER1 and PER2 genes, studies in animals generally show that it does not contribute ... The PER3 gene encodes the period circadian protein homolog 3 protein in humans. PER3 is a paralog to the PER1 and PER2 genes. ...
"LAMP1 lysosomal-associated membrane protein 1". Entrez Gene. Eskelinen EL (2006). "Roles of LAMP-1 and LAMP-2 in lysosome ... is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 ... flanking sequence of lamp-2 gene and comparison of exon organization in two genes". The Journal of Biological Chemistry. 268 ( ... flanking sequence of lamp-2 gene and comparison of exon organization in two genes". The Journal of Biological Chemistry. 268 ( ...
"EMX2 empty spiracles homeobox 2". Entrez Gene. Walldorf U, Gehring WJ (June 1992). "Empty spiracles, a gap gene containing a ... 1992). "Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral ... gene. The "empty spiracles gene" is needed for the proper head development/formation as well as the development of posterior ... Homeobox protein Emx2 is a protein that in humans is encoded by the EMX2 gene. The homeodomain transcription factor EMX2 is ...
"POMC proopiomelanocortin". Entrez Gene. Mohamed FE, Hamza RT, Amr NH, Youssef AM, Kamal TM, Mahmoud RA (2017). "Study of ... The POMC gene is located on chromosome 2p23.3. The POMC gene is expressed in both the anterior and intermediate lobes of the ... Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. A study ... This gene encodes a 285-amino acid polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational ...
"LINGO1 leucine rich repeat and Ig domain containing 1". Entrez Gene. Carim-Todd L, Escarceller M, Estivill X, Sumoy L (Dec 2003 ... "LINGO1 Gene". Gene Cards. Retrieved 2015-10-18. Andrews JL, Fernandez-Enright F (2015). "A decade from discovery to therapy: ... LINGO-1 is coded by the LINGO-1 gene, which is located on the human chromosome 15, more precisely on the locus 15q24-26, which ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 15, All articles with unsourced ...
Entrez Gene. United States National Library of Medicine. Rousseau-Merck MF, Pizon V, Tavitian A, Berger R (1990). "Chromosome ... Genes on human chromosome 1, Genes on human chromosome 12, Wikipedia articles incorporating text from the United States ... Human genes that encode Ras-related proteins include: RAP1A, RAP1B RAP2A, RAP2B, RAP2C RAB5C "RAP1A RAP1A, member of RAS ... mapping of the human RAS-related RAP1A, RAP1B, and RAP2 genes to chromosomes 1p12----p13, 12q14, and 13q34, respectively". ...
SKA1 SKA3 GR (Glucocorticoid receptor) "SKA2". Entrez Gene. Retrieved 3 Aug 2014. Hanisch A, Silljé HH, Nigg EA (November 2006 ... The SKA2 gene along with PRR11 gene as a pair is essential for the development of lung cancer. The pair of genes are separated ... Articles with short description, Short description matches Wikidata, Human genes, Protein pages needing a picture, Genes on ... SKA2 gene product is a 121 amino acid long chain and a molecular weight of 14,188 Da containing mainly 3 helices. Homologues of ...
"Entrez gene". Meher AK, Bal NC, Chary KV, Arora A (Apr 2006). "Mycobacterium tuberculosis H37Rv ESAT-6-CFP-10 compleand ... It forms a 1:1 heterodimeric complex with ESAT-6. Both genes are expressed from the RD1 region of the bacterial genome and play ... is a protein that is encoded by the esxB gene. CFP-10 is a 10 kDa secreted antigen from Mycobacterium tuberculosis. ...
Entrez Gene. National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine. "#CAA39671". NCBI Entrez ... Gene polymorphism of interleukin-1 family, interleukin 6, and polymorphic GT repeat of the CRP gene do affect the usual CRP ... 2020). "C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene ... The CRP gene is located on chromosome 1 (1q23.2). It is a member of the small pentraxins family. The monomer has 224 amino ...
"SMAD4 SMAD family member 4". Entrez Gene. "SMAD 4". The Genetics Home Reference Website. Zawel L, Dai JL, Buckhaults P, Zhou S ... In mammals, SMAD4 is coded by a gene located on chromosome 18. In humans, the SMAD4 gene contains 54 829 base pairs and is ... During Drosophila research, it was found that a mutation in the gene MAD in the mother repressed the gene decapentaplegic in ... Genetic experiments such as gene knockout (KO), which consist in modifying or inactivating a gene, can be carried out in order ...
"Entrez Gene: IYD Iodotyrosine deiodinase". Entrez Gene. United States National Library of Medicine. Rosenberg IN, Goswami A ( ... Moreno JC (2003). "Identification of novel genes involved in congenital hypothyroidism using serial analysis of gene expression ... The gene encoding this enzyme has been recently identified. The sequence of amino acids of iodotyrosine deiodinase is highly ... Mutations in the gene encoding iodotyrosine deiodinase can affect enzyme function and be detrimental to human health. Iodide is ...
"UPF0488 protein C8orf33 [Homo sapiens]". Entrez Protein. "C8orf33". Gene Cards. "Gene: C8orf33 ENSG00000182307". Ensembl. ... "C8orf33 chromosome 8 open reading frame 33 [Homo sapiens]". Entrez Gene. Ma C, Chen HI, Flores M, Huang Y, Chen Y (2013). "BRCA ... This gene is a member of the Human CCDS set: CCDS34974.1 This gene is a member of the Human CCDS set: CCDS34974. C8orf33 ... Gene expression seems to increase in the obesity-resistant categories The promoter region for c8orf33 covers 1191 base pairs of ...
"C9orf127 chromosome 9 open reading frame 127". Entrez Gene. "Erythromelalgia - NORD (National Organization for Rare Disorders ... This gene also plays a negative role in an Epidermal Growth Factor Receptor (EGFR) pathway. It can delay cell cycle G0-G1 ... Ma J, Li J, Zhou J, Li XL, Tang K, Zhou M, Yang JB, Yan Q, Shen SR, Hu GX, Li GY (December 2002). "Profiling genes ... Zhang XM, Wang XY, Sheng SR, Wang JR, Li J (August 2003). "Expression of tumor related genes NGX6, NAG-7, BRD7 in gastric and ...
"AP1S2 adaptor-related protein complex 1, sigma 2 subunit". Entrez Gene. National Center for Biotechnology Information, U.S. ... This gene is involved in CNS and pancreas development. Mutations in this gene cause X-linked intellectual disability and ... This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C ... It has been estimated there are ~200 genes involved in this syndrome; of these ~100 have been identified. Many of these genes ...
Mol Genet Genomic Med "FBN1 fibrillin 1". Entrez Gene. Online Mendelian Inheritance in Man (OMIM): FIBRILLIN 1; FBN1 - 134797 ... This condition has been associated with mutations in the Fibrillin 1 (FBN1) gene. Mutations in this gene have also been ...
"TKTL1 transketolase-like 1". Entrez Gene. U.S. National Library of Medicine. Pinson, Anneline; Xing, Lei; Namba, Takashi; ... TKTL1 is a gene that arose from the transketolase gene of lower vertebrates by gene duplication in the course of vertebrate ... there is another member of the transketolase gene family in mammals, the TKTL2 gene. The TKTL2 gene arose by integration of a ... Contrary to the TKT and TKTL1 genes, it is not yet clear in the case of the TKTL2 gene whether and what function TKTL2 performs ...
"PTGER2 prostaglandin E receptor 2 (human)". Entrez Gene. National Center for Biotechnology Information, U.S. National Library ... EP2 gene knockout mice have less lung, breast, skin, and colon cancers following exposure to carcinogens. Knockout of this gene ... and chromosomal localization of the gene encoding the human prostaglandin E(2) receptor EP2 subtype". Gene. 237 (2): 393-402. ... The PTGER2 gene is located on human chromosome 14 at position p22.1 (i.e. 14q22.1), contains 2 introns and 3 exons, and codes ...