... function occurs through the inhibition of mycolic acid synthesis through the NADH-dependent enoyl-acyl carrier protein (ACP)- ... reductase. This is encoded by the inhA gene. As a result, isoniazid resistance is primarily due to mutations within inhA and ... The mycobacterial membrane protein large (MmpL) proteins are transmembrane proteins which play a key role in the synthesis of ... These proteins have a conserved N-terminal motif, deletion of which impairs growth in macrophages and granulomas. Noncoding ...
NADH-Enoyl+ACP+Reductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) EC 1.3.1.9 Portal: Biology ( ... Enoyl-(acyl-carrier-protein) reductase (NADPH, A-specific) Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific) Cis-2- ... Enoyl-acyl carrier protein reductase (or ENR) (EC 1.3.1.9), is a key enzyme of the type II fatty acid synthesis (FAS) system. ... "Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum". ...
This complex binds tightly to the enoyl-acyl carrier protein reductase InhA, thereby blocking the natural enoyl-AcpM substrate ... KatG catalyzes the formation of the isonicotinic acyl radical, which spontaneously couples with NADH to form the nicotinoyl-NAD ... March 2009). "An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of ... purified protein derivative) reaction of at least 5 mm induration Contacts of people with tuberculosis and who have a PPD ...
... to produce adducts that are very potent inhibitors of the enzymes enoyl-acyl carrier protein reductase, and dihydrofolate ... with NADH-ubiquinone oxidoreductase commonly being called NADH dehydrogenase or sometimes coenzyme Q reductase. There are many ... In this case, an enzyme can produce one of two stereoisomers of NADH. Despite the similarity in how proteins bind the two ... The properties of the fluorescence signal changes when NADH binds to proteins, so these changes can be used to measure ...
... enoyl-(acyl-carrier-protein) reductase (nadh) MeSH D08.811.682.660.390 - enoyl-(acyl-carrier protein) reductase (nadph, b- ... nitrate reductase MeSH D08.811.682.655.500.200 - nitrate reductase (nadh) MeSH D08.811.682.655.500.249 - nitrate reductase (nad ... acyl-carrier protein s-acetyltransferase MeSH D08.811.913.050.134.060 - acetyl-CoA C-acetyltransferase MeSH D08.811.913.050. ... acyl-carrier protein s-malonyltransferase MeSH D08.811.913.050.173 - 1-acylglycerol-3-phosphate O-acyltransferase MeSH D08.811. ...
... enoyl-[acyl-carrier-protein] reductase (NADH) EC 1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) EC 1.3. ... 2-alkenal reductase (NADP+) * EC 1.3.1.103: 2-haloacrylate reductase * EC 1.3.1.104: enoyl-[acyl-carrier-protein] reductase ( ... hydroxycinnamoyl-CoA reductase * EC 1.3.1.118: meromycolic acid enoyl-[acyl-carrier-protein] reductase * EC 1.3.1.119: ... acyl-lipid Δ6-acetylenase EC 1.14.19.39: acyl-lipid Δ12-acetylenase EC 1.14.19.40: hex-5-enoyl-[acyl-carrier protein] ...
These include the acyl carrier protein (ACP), acetyl transferase (AT), ketosynthase (KS), malonyl transferase (MT; which can ... and enoyl reductase (ER). An example of the possible modular biosynthetic pathway detailing the combination of these enzymes ... As NADH-dehydrogenase is responsible for the conversion of NADH to NAD+ as well as the establishment of a proton gradient in ... Like other acetogenins, it is a mitochondrial complex I (NADH-dehydrogenase) inhibitor. ...
... acyl-carrier-protein) synthase (ACPS) domain. ACPS attaches the 4′-phosphopantetheine prosthetic group of CoA to the acyl ... Another reduction reaction then performed in the enoyl reductase (ER) domain of the β subunit to form a saturated acyl-ACP ... Portal: Biology (EC 2.3.1, NADPH-dependent enzymes, NADH-dependent enzymes, Enzymes of known structure). ... Leibundgut M, Jenni S, Frick C, Ban N (April 2007). "Structural basis for substrate delivery by acyl carrier protein in the ...
Trans-2-enoyl-CoA reductase, mitochondrial MFAP2: Microfibrillar-associated protein 2 MIB2 (1p36) MIER1 (1p31) MIGA1: encoding ... encoding protein Solute carrier family 30 member 10 SLC39A1 (1q21) SLC50A1: Solute carrier family 50 member 1 SMCP: Sperm ... acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain ACTG1P6: encoding protein Actin, gamma 1 pseudogene 6 ACTL8: Actin- ... encoding protein Nadh dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kda, pseudogene 1 NGF: Nerve Growth Factor NOL9: ...
... holo-CmaA peptidyl-carrier protein ligase EC 6.2.1.47: Medium-chain-fatty-acid-(acyl-carrier-protein) ligase EC 6.2.1.48: ... reductase EC 1.17.4.1 Ribonucleoside-triphosphate reductase EC 1.17.4.2 Vitamin K epoxide reductase Vitamin-K-epoxide reductase ... EC 5.3.3 Enoyl CoA isomerase (EC 5.3.3.8) Category:EC 5.3.4 Protein disulfide isomerase (EC 5.3.4.1) Category:EC 5.4.2 ... NADH dehydrogenase EC 1.6.5.3 Category:EC 1.6.6 (with a nitrogenous group as acceptor) Category:EC 1.6.7 now Category:EC 1.18.1 ...
Abbreviations: ACP - Acyl carrier protein, CoA - Coenzyme A, NADP - Nicotinamide adenine dinucleotide phosphate. Note that ... yielding 1 FADH2 Hydration by enoyl-CoA hydratase Dehydrogenation by 3-hydroxyacyl-CoA dehydrogenase, yielding 1 NADH + H+ ... "Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications". The ... to give a fatty acyl-adenylate, which then reacts with free coenzyme A to give a fatty acyl-CoA molecule. In order for the acyl ...