2007). "Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT ... Bishop N, Woodman P (2000). "ATPase-defective Mammalian VPS4 Localizes to Aberrant Endosomes and Impairs Cholesterol ... and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B". Biochem. J. 391 (Pt 3): ...
"Rab14 is involved in membrane trafficking between the Golgi complex and endosomes". Mol Biol Cell. 15 (5): 2218-29. doi:10.1091 ...
"A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes". Traffic. 7 (8): 1017-31. doi: ...
... a member of the syntaxin family localized to the endosome". J. Biol. Chem. 273 (12): 6944-50. doi:10.1074/jbc.273.12.6944. PMID ... "Preferential association of syntaxin 8 with the early endosome" (PDF). J. Cell Sci. 113 (6): 997-1008. doi:10.1242/jcs.113.6. ... a Novel Synaptobrevin/VAMP-Like Protein Preferentially Associated with the Early Endosome". Mol. Biol. Cell. 9 (6): 1549-63. ... "Syntaxin 13 Mediates Cycling of Plasma Membrane Proteins via Tubulovesicular Recycling Endosomes". J. Cell Biol. 143 (4): 957- ...
"Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 ( ... "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 ( ... "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function". The EMBO ... "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". The Journal of Cell Biology ...
"Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". J. Cell Biol. 143 (4): 957- ...
Rab11 specifically plays a key role in endocytic trafficking and recycling through guiding early endosomes to endosome ... This is in contrast to the fast constitutive recycling route which allows for the direct transport of cargo from the endosome ... Studies have shown that Rab11FIP5 localizes to the perinuclear endosomes where it aids in sorting vesicles into the slow ... The requirement of Rab11FIP5 for regulated DCV exocytosis may be attributed to its role in endosome-mediated retrograde ...
"Intercellular transfer to signalling endosomes regulates an ex vivo bone marrow niche". Nature Cell Biology. 11 (3): 303-311. ...
"Rab9 functions in transport between late endosomes and the trans Golgi network". The EMBO Journal. 12 (2): 677-682. doi:10.1002 ... "Rab9 functions in transport between late endosomes and the trans Golgi network Rab GTPases: specifying and deciphering ...
Soldati T, Rancaño C, Geissler H, Pfeffer SR (1995). "Rab7 and Rab9 are recruited onto late endosomes by biochemically ...
Neefjes further expanded his work on endosomes to phagosomes and intracellular bacteria. By combining chemistry, cell biology ... In 2017, Neefjes and his team made fundamental discoveries regarding endosome positioning by the endoplasmic reticulum. ...
Germination occurs both extracellularly or in type II pneumocyte endosomes containing conidia. Following germination, ...
... on early endosomes". Genes Cells. 11 (6): 593-606. doi:10.1111/j.1365-2443.2006.00963.x. PMID 16716190. S2CID 30077507. Reyes- ...
The "factories" in this case, are the host cell's endosomes and lysosomes. The role of the endosome was explained above in the ... After endocytic uptake, the virus is quickly delivered to the early endosome compartment, where a low pH then lyses the ... endosome and virus, exposing the cytoplasm to viral nucleocapsid. Cholesterol is also necessary for the Alphavirus to undergo ...
"A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes". Molecular Cell. 6 (6): 1437-48. ... "A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes". Molecular Cell. 6 (6): 1437-48. ...
Düwel M, Ungewickell EJ (2007). "Clathrin-dependent Association of CVAK104 with Endosomes and the Trans-Golgi Network". Mol. ...
Kutateladze, Tatiana; Overduin, Michael (2001). "Structural Mechanism of Endosome Docking by the FYVE Domain". Science. 291 ( ...
Distinct types of membranes also create intracellular organelles: endosome; smooth and rough endoplasmic reticulum; ...
Johnson IR, Parkinson-Lawrence EJ, Shandala T, Weigert R, Butler LM, Brooks DA (December 2014). "Altered endosome biogenesis in ...
PtdIns3P can be found mostly in membranes of early endosomes, PtdIns(3,5)P2 in late endosomes, and PtdIns4P in the Golgi). ... Kutateladze T, Overduin M (March 2001). "Structural mechanism of endosome docking by the FYVE domain". Science. 291 (5509): ...
Marlin MC, Li G (2015). "Biogenesis and function of the NGF/TrkA signaling endosome". International Review of Cell and ...
The endocytic vesicles (endosomes) rapidly become acidified to allow the FR to release its ligand. Afterwards, the empty FR ... Lee RJ, Wang S, Low PS (July 1996). "Measurement of endosome pH following folate receptor-mediated endocytosis". Biochim. ...
Marlin MC, Li G (2015). "Biogenesis and function of the NGF/TrkA signaling endosome". International Review of Cell and ...
2006). "Differential regulation of AQP2 trafficking in endosomes by microtubules and actin filaments". Histochem. Cell Biol. ...
In FEME however, endosomes form when coated by actin, and internalise endophilin A2. Each endocytic pathway focuses on a ... In Clathrin-dependent endocytic pathways, endosomes budding from the cell membrane into the cell will form in clathrin pits, ...
Ramanathan HN, Ye Y (February 2012). "The p97 ATPase associates with EEA1 to regulate the size of early endosomes". Cell ... and endosomes. The subcellular localization of CDC48 has not been fully characterized, but is likely to be similar to the ...
Hunziker W, Peters PJ (Jul 1998). "Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in ...
"Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes". Nature Cell Biology. 4 (2 ...
It is a component of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ... Teo H, Perisic O, Gonzalez B, Williams RL (October 2004). "ESCRT-II, an endosome-associated complex required for protein ... Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD (August 2002). "Endosome-associated complex, ESCRT-II, recruits transport ... 2004). "Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes". J. Cell Biol. 164 (6): 923- ...
"Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at ... "A phosphoinositide conversion mechanism for exit from endosomes." (PDF), Nature, vol. 529, no. 7586, pp. 408-412, Bibcode: ...
"Sonic hedgehog induces the segregation of patched and smoothened in endosomes". Current Biology. 12 (12): 983-95. doi:10.1016/ ...
HLA-DO starts binding to DM in early endosomes, but is expressed less in late endosomes/lysosomes. The binding between HLA-DM ... Kinetic analysis studies have shown that HLA-DM loading occurs quickly and in many endosomes. Along the membrane of an endosome ... HLA-DM is a molecular chaperone that works in lysosomes and endosomes in cells of the immune system. It works in APCs like ... This process occurs in endosomes once they have left the ER containing MHC and HLA-DM that have fused with antigen-containing ...
"Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity". Cell. 135 (3): 535-48. doi:10.1016/j. ... Myosin-Vb is related to the creation of memories by actin-dependent trafficking of AMPA receptor containing recycling endosomes ... for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in ...
An MHC class II-like structure, HLA-DM, removes CLIP and replaces it with a peptide from the endosome. The stable MHC class-II ... Proteins are endocytosed and degraded by acid-dependent proteases in endosomes; this process takes about an hour. The nascent ... This fuses with a late endosome containing the endocytosed, degraded proteins. The invariant chain is then broken down in ... Mycobacterium tuberculosis inhibits phagosome-endosome fusion, thus avoiding being destroyed by the harsh environment of the ...
"SNX-BAR-Mediated Endosome Tubulation is Co-ordinated with Endosome Maturation". Traffic. 13 (1): 94-107. doi:10.1111/j.1600- ... The SNX8 is a sorting nexin protein involved in intracellular molecular traffic from the early endosomes to the TGN. It is ... This hypothesis is supported by the fact that SNX8 mainly colocalizes with Rab5 at early endosomes and partially with Rab4 at ... SNX8 is thought to be an adaptor protein involved in the endosome-to-Golgi transport pathway, participating in endocytosis and ...
"Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans- ... Members of the Rab11 subfamily act in recycling of proteins from the endosomes to the plasma membrane, in transport of ... Rowe, Regina K.; Jason W. Suszko; Andrew Pekosz (2008-12-20). "Roles for the recycling endosome, Rab8, and Rab11 in hantavirus ... Replicated viruses benefit from Rab11 mediated recycling endosome pathway to exit the cell and infect surrounding tissue. ...
What is left is known as an early endosome. The early endosome merges with a late endosome. This is the vesicle that allows the ... Here there are hydrolytic enzymes that will degrade the contents of the late endosome. Sometimes, rather than being degraded, ...
The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes ... The related pathogen Legionella longbeachae recruits EEA1 and appears to replicate within a modified early endosome. endosome ... early+endosome+antigen+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Overview of all the ... Barysch SV, Aggarwal S, Jahn R, Rizzoli SO (Jun 2009). "Sorting in early endosomes reveals connections to docking- and fusion- ...
Valdez AC, Cabaniols JP, Brown MJ, Roche PA (Mar 1999). "Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans ... "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". The Journal of Cell Biology ...
"Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". The Journal of Cell Biology ...
These function as the machinery for the homotypic fusion of late endosomes. Model organisms have been used in the study of STX8 ... "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function". The EMBO ... "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function". The EMBO ... "Preferential association of syntaxin 8 with the early endosome". Journal of Cell Science. 113 ( Pt 6) (6): 997-1008. doi: ...
This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form ... 2001). "Self-assembly and binding of a sorting nexin to sorting endosomes". J. Cell Sci. 114 (Pt 9): 1743-56. doi:10.1242/jcs. ... 2004). "Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and ... "Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of ...
The catalytic domains of CCTs probably enter the cytoplasm from acidic endosomes. The toxins form ion-permeable channels in ...
Bishop N, Woodman P (April 2000). "ATPase-defective Mammalian VPS4 Localizes to Aberrant Endosomes and Impairs Cholesterol ...
"Molecular analysis of vesicular transport from endosomes to the trans Golgi network , WorldCat.org". www.worldcat.org. ... where she studied vesicular transport from endosomes to the Golgi complex. She completed a course on developmental neurobiology ...
Sun W, Yan Q, Vida TA, Bean AJ (July 2003). "Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE ... a member of the syntaxin family localized to the endosome". The Journal of Biological Chemistry. 273 (12): 6944-50. doi:10.1074 ... "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". The Journal of Cell Biology ...
"Aggregation of nanoparticles in endosomes and lysosomes produces surface-enhanced Raman spectroscopy". Journal of Nanophotonics ...