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*  Palmitoylethanolamide
Endocannabinoid lipids like PEA are widely distributed in nature, in a variety of plant, invertebrate, and mammalian tissues. ... Yu, H. L.; Deng, X. Q.; Li, Y. J.; Li, Y. C.; Quan, Z. S.; Sun, X. Y. (2011). "N-palmitoylethanolamide, an endocannabinoid, ... Walker, J. M.; Krey, J. F.; Chu, C. J.; Huang, S. M. (2002). "Endocannabinoids and related fatty acid derivatives in pain ... PEA cannot strictly be considered a classic endocannabinoid because it lacks affinity for the cannabinoid receptors CB1 and CB2 ...
*  Cannabinoid receptor type 2
The role of endocannabinoids, as such, play an important role in inhibiting unnecessary immune action upon the natural gut ... Changes in endocannabinoid levels and/or CB2 receptor expressions have been reported in almost all diseases affecting humans, ... Matias I, Pochard P, Orlando P, Salzet M, Pestel J, Di Marzo V (Aug 2002). "Presence and regulation of the endocannabinoid ... Storr MA, Yüce B, Andrews CN, Sharkey KA (Aug 2008). "The role of the endocannabinoid system in the pathophysiology and ...
*  Endocannabinoid system
Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide ... The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based ... A related study found that endocannabinoids affect taste perception in taste cells In taste cells, endocannabinoids were shown ... Endocannabinoid enhancer Endocannabinoid reuptake inhibitor Cannabinoid receptor antagonist Jasmonate Klein, Carolin; Hill, ...
*  Endocannabinoid transporter
Endocannabinoid reuptake inhibitor Endocannabinoid enhancer Endocannabinoid system Kaczocha, Martin; Lin, Qingqing; Nelson, ... The endocannabinoid transporters (eCBTs) are transport proteins for the endocannabinoids. Most neurotransmitters are water- ... The endocannabinoids (anandamide, AEA, and 2-arachidonoylglycerol, 2-AG) on the other hand, are non-charged lipids that readily ... However, since the endocannabinoids are water immiscible, protein transporters have been described that act as carriers to ...
*  Endocannabinoid enhancer
An endocannabinoid enhancer (eCBE) is a type of cannabinoidergic drug that enhances the activity of the endocannabinoid system ... and endocannabinoid transporter (eCBT) inhibitors (or "endocannabinoid reuptake inhibitors" ("eCBRIs")). An example of an ... Di Marzo, Vincenzo (2008). "Targeting the endocannabinoid system: to enhance or reduce?". Nature Reviews Drug Discovery. 7 (5 ... Saito, Viviane M.; Wotjak, Carsten T.; Moreira, Fabrício A. (2010). "Pharmacological exploitation of the endocannabinoid system ...
*  Endocannabinoid reuptake inhibitor
AM404 AM1172 LY-2183240 O-2093 OMDM-2 UCM-707 VDM-11 Guineensine WOBE437 and RX-055 Endocannabinoid enhancer Endocannabinoid ... are drugs which limit the reabsorption of endocannabinoid neurotransmitters by the releasing neuron. Endocannabinoid uptake ... The inhibition of endocannabinoid reuptake raises the amount of those neurotransmitters available in the synaptic cleft and ... A study done in 2004 on rats with thyroid tumors showed that reuptake inhibition of the endocannabinoid system using VDM-11 and ...
*  Metabolic syndrome
The involvement of the endocannabinoid system in the development of metabolic syndrome is indisputable. Endocannabinoid ... The endocannabinoid system (ECS) is known to exert regulatory control on essentially every aspect related to the search for, ... The endocannabinoid signaling system plays a critical role in motivational homeostasis as a conduit for reward stimuli and a ... Endocannabinoid-system hyperactivity through CB1 receptor transmission is considered contributory to a range of appetitive ...
*  Eicosanoid
Endocannabinoids]". La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics (in Italian). 34 (2): 65-72. doi:10.4081 ... Endocannabinoids are certain glycerolipids or dopamine that are esterified to polyunsaturated fatty acids that activate ...
*  Cannabis Science Inc.
"UCCS - University of Colorado at Colorado Springs , BIOL 408 - Endocannabinoids". MyEdu. Retrieved 2012-07-04. Scot Kersgaard ( ...
*  Retrograde signaling
Endocannabinoids like anandamide are known to act as retrograde messengers, as is nitric oxide. Retrograde signaling may also ... The endocannabinoids anandamide and/or 2-AG, acting through G-protein coupled cannabinoid receptors, may play an important role ... Alger BE (2002). "Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids". Prog. Neurobiol ... Kreitzer, A.; Regehr, W. G. (2002). "Retrograde signaling by endocannabinoids". Current Opinion in Neurobiology. 12 (3): 324- ...
*  Crohn's disease
Cannabinoids and/or modulation of the endocannabinoid system is a novel therapeutic means for the treatment of numerous GI ... Massa F, Storr M, Lutz B; Storr; Lutz (2005). "The endocannabinoid system in the physiology and pathophysiology of the ... Massa F, Monory K; Monory (2007). "Endocannabinoids and the gastrointestinal tract". Journal of Endocrinological Investigation ...
*  Effects of cannabis
Endogenous cannabinoids ("endocannabinoids") were discovered in cow's milk and soft cheeses. Endocannabinoids are also found in ... The Endocannabinoid-CB Receptor System: Importance for development and in pediatric disease Neuroendocrinology Letters Nos.1/2 ... Scientists have claimed to be able to explain what causes the increase in appetite, concluding that "endocannabinoids in the ... Fride E, Bregman T, Kirkham TC (April 2005). "Endocannabinoids and food intake: newborn suckling and appetite regulation in ...
*  Anandamide
Endocannabinoid transporters for anandamide and 2-arachidonoylglycerol include the heat shock proteins (Hsp70s) and fatty acid ... Pacher P, Batkai S, Kunos G (2006). "The Endocannabinoid System as an Emerging Target of Pharmacotherapy". Pharmacol. Rev. 58 ( ... El-Talatini MR, Taylor AH, Konje JC (April 2010). "The relationship between plasma levels of the endocannabinoid, anandamide, ... Mahler SV, Smith KS, Berridge KC (November 2007). "Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus ...
*  Cannabinoid
... the net effect is a decrease in the excitability of the endocannabinoid-releasing cell.[citation needed] Endocannabinoids are ... Cannabinoid receptor antagonist Endocannabinoid enhancer Endocannabinoid reuptake inhibitor Cancer and nausea § Cannabinoids ... making it a strong contender as the sixth endocannabinoid. Endocannabinoids serve as intercellular 'lipid messengers', ... Furthermore, endocannabinoids are lipophilic molecules that are not very soluble in water. They are not stored in vesicles and ...
*  Nonclassic eicosanoid
... and endocannabinoids. LTs and prostanoids are sometimes termed 'classic eicosanoids' in contrast to the 'novel', 'nonclassic' ... endocannabinoids). Also included are Side products from the classic eicosanoid biosynthesis, (levuglandins, Oxoeicosanoids); ...
*  N-Arachidonoyl dopamine
... (NADA) is an endocannabinoid that acts as an agonist of the CB1 receptor and the transient receptor ... NADA was first described as a putative endocannabinoid (agonist for the CB1 receptor) in 2000 and was subsequently identified ... "The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of ... Endocannabinoid Bisogno, T.; Melck, D.; Bobrov MYu, null; Gretskaya, N. M.; Bezuglov, V. V.; De Petrocellis, L.; Di Marzo, V. ( ...
*  GPR55
... is activated by the plant cannabinoids Δ9-THC, and the endocannabinoids anandamide, 2-AG, noladin ether in the low ... Andradas, Clara (2013). Endocannabinoids Actions at Atypical, Non-cannabinoid Receptors. Springer Verlag. pp. 115-133. ISBN 978 ... "The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects ...
*  Pain management
Zogopoulos P, Vasileiou I, Patsouris E, Theocharis SE (Feb 2013). "The role of endocannabinoids in pain modulation". Fundam ...
*  Psychoactive drug
"Inhibitors of the Enzymic Hydrolysis of Endocannabinoids". Tocris.com. Retrieved 2013-11-23. Glick, Stanley D; Maisonneuve, ...
*  Nonsteroidal anti-inflammatory drug
NSAIDs interact with the endocannabinoid system and its endocannabinoids, as COX2 have been shown to utilize endocannabinoids ... Fowler, C J (2017-01-27). "The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action". British Journal of ... Various widely used nonsteroidal anti-inflammatory drugs (NSAIDs) enhance endocannabinoid signaling by blocking the anandamide- ... Oxygenation of Endocannabinoids". The Journal of Biological Chemistry. 283 (13): 8065-8069. doi:10.1074/jbc.R800005200. ISSN ...
*  Management of multiple sclerosis
Pryce, G; Baker, D (2015). "Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis". Handbook of experimental ...
*  NAGly receptor
endoCANNABINOIDS: actions at non-CB1/CB2 cannabinoid receptors. New York: Springer. ISBN 978-1-4614-4668-2. Chiang N, Dalli J, ... McHugh D, Bradshaw HB (2012). "GPR18 and NAGly Signaling: New Members of the Endocannabinoid Family or Distant Cousins?". In ...
*  Wade Regehr
Kreitzer Anatol C; Carter Adam G; Regehr Wade G (2002) Inhibition of interneuron firing extends the spread of endocannabinoid ... Safo Patrick K; Regehr Wade G (2005) Endocannabinoids control the induction of cerebellar LTD. Neuron 2005;48(4):647-59. Xu- ... Kreitzer AC, Carter AG, Regehr WG (2002) Inhibition of interneuron firing extends the spread of endocannabinoid signaling in ... Neuron 2008;59(1):3-5. Best Aaron R; Regehr Wade G (2008) Serotonin evokes endocannabinoid release and retrogradely suppresses ...
*  Fatty acid amide hydrolase
Endocannabinoid enhancer Endocannabinoid reuptake inhibitor GRCh38: Ensembl release 89: ENSG00000117480 - Ensembl, May 2017 ... Ulugöl A (2014). "The endocannabinoid system as a potential therapeutic target for pain modulation". Balkan Medical Journal. 31 ... Berardi A, Schelling G, Campolongo P (September 2016). "The endocannabinoid system and Post Traumatic Stress Disorder (PTSD): ... Fowler CJ (2015). "The Potential of Inhibitors of Endocannabinoid Metabolism for Drug Development: A Critical Review". Handbook ...
*  N-Acylamides
Fezza, F., Dillwith, J. W., Bisogno, T., Tucker, J. S., Di Marzo, V., & Sauer, J. R. (2003). Endocannabinoids and related fatty ... Largely studied in context with lipid signaling, the class of compounds plays an important role in endocannabinoid systems ... Salzet, M., Breton, C., Bisogno, T., & Di Marzo, V. (2000). Comparative biology of the endocannabinoid system. European Journal ... 11Elphick, M. R., Satou, Y., & Satoh, N. (2003). The invertebrate ancestry of endocannabinoid signalling: an orthologue of ...