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*  Enalaprilat
As a prodrug, enalapril is metabolized in vivo to the active form enalaprilat by various esterases. Peak plasma enalaprilat ... enalaprilat was only suitable for intravenous administration. This was overcome by the esterification of enalaprilat with ... Enalaprilat, however, had a problem of its own. The consequence of the structural modifications was to give it ionisation ... Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed ...
*  Enalapril
Enalaprilat, however, had a problem of its own in that it had poor oral availability. This was overcome by the researchers at ... Enalaprilat was developed partly to overcome these limitations of captopril. The sulfhydryl moiety was replaced by a ... "Enalaprilat/Enalapril Maleate". The American Society of Health-System Pharmacists. Archived from the original on 21 December ... By inhibiting the ACE, enalaprilat, the active metabolite of enalapril, decreases levels of angiotensin II leading to less ...
*  Lisinopril
Enalapril is actually a prodrug; the active metabolite is enalaprilat. Scientists at Merck created lisinopril by systematically ... altering each structural unit of enalaprilat, substituting various amino acids. It turned out that adding lysine at one end of ...
*  Discovery and development of ACE inhibitors
The results were 2 active inhibitors: Enalaprilat and Lisinopril. These compounds both have phenylalanine in R position which ... The result was thus these two new, potent tripeptide analogues with zinc-coordinating carboxyl group: Enalaprilat and ...
*  Petasis reaction
Petasis and coworkers prepared Enalaprilat, an ACE inhibitor, with this method. Synthesis of peptidomimetic heterocycles When ...
*  Fosinopril
... at proved to have the same problem as enalaprilat and the other carboxylate-containing ACE inhibitors (namely poor ... Comparison of the pharmacokinetics of fosinoprilat with enalaprilat and lisinopril in patients with congestive heart failure ...
*  List of drugs: Em-Ep
enalapril (INN) enalaprilat enalaprilat (INN) enalkiren (INN) enazadrem (INN) Enbrel (Amgen) enbucrilate (INN) encainide (INN) ...
*  List of MeSH codes (D12.644)
... enalaprilat MeSH D12.644.456.345.575 --- glycylglycine MeSH D12.644.456.345.600 --- lisinopril MeSH D12.644.456.400 --- n- ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: Antihypertensives: ACE Inhibitors
Angiotensin-converting enzyme inhibitors are a class of medications used in the treatment of hypertension (high blood pressure), congestive heart failure, and other conditions.