For differentiation to occur, the human embryonic stem cell line is removed from the supporting cells to form embryoid bodies, ... are equivalent to embryonic stem cells, leading these cells to be known as induced pluripotent stem cells (iPS cells). This ... Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- ... "Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer". Cell. 153 (6): 1228-1238. doi:10.1016/j.cell.2013.05.006 ...
Kursad Turksen (2006). Embryonic Stem Cell Protocols: Differentiation models. Humana Press. pp. 263-. ISBN 978-1-58829-784-6. ... Interstitial cells of Cajal (ICC) are interstitial cells found in the gastrointestinal tract. Before considering these cells ... Myenteric interstitial cells of Cajal (ICC-MY) serve as pacemaker cells that generate the bioelectrical events known as slow ... This cell type can be characterized morphologically as having a small cell body often triangular or stellate-shaped with ...
"Hepatic differentiation of murine embryonic stem cells". Experimental Cell Research. 272 (1): 15-22. doi:10.1006/excr.2001.5396 ... February 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell ... August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of ...
"Metabolic oxidation regulates embryonic stem cell differentiation". Nature Chemical Biology. 6 (6): 411-417. doi:10.1038/ ... Differentiation is the process by which specialized cells from less specialized cells such as stem cells. Stem cells are ... and that all cells arise from preexisting cells through cell division. Most cells are very small, with diameters ranging from 1 ... Cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, ...
Keller GM (December 1995). "In vitro differentiation of embryonic stem cells". Current Opinion in Cell Biology. 7 (6): 862-9. ... These reduced cell numbers make studying non-dividing or slow dividing cells (e.g., stem cells) easier than traditional culture ... cell-cell interactions, cell-molecule interactions, cell-substrate interactions), and physicochemical (pH, CO2, temperature, O2 ... Perfusion in microfluidic cell culture is important to enable long culture periods on-chip and cell differentiation. Other ...
"Metabolic oxidation regulates embryonic stem cell differentiation". Nature Chemical Biology. 6 (6): 411-417. doi:10.1038/ ... identified neuroprotectin D1 as a metabolite that promotes stem cell differentiation. In 1996 whole virus analysis was ... Giera, Martin; Yanes, Oscar; Siuzdak, Gary (2022-01-04). "Metabolite discovery: Biochemistry's scientific driver". Cell ... Nature Reviews Molecular Cell Biology. 17 (7): 451-459. doi:10.1038/nrm.2016.25. ISSN 1471-0080. PMC 5729912. PMID 26979502. ...
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"A small molecule primes embryonic stem cells for differentiation". Cell Stem Cell. 4 (5): 416-26. doi:10.1016/j.stem.2009.04. ... stauprimide has been shown to increase the efficiency of the directed differentiation of mouse and human embryonic stem cells ... leading to differentiation of stem cells. Staurosporine Rebeccamycin K252a Midostaurin Caravatti, Giorgio; Meyer, Thomas; ...
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Engineering microenvironments for embryonic stem cell differentiation to cardiomyocytes. Regenerative Medicine. 4: 721-32. PMID ... The system again uses the approach of targeting ICAM-1 on TNBC cells via antibody binding of the liposome to the cells in order ... Further the specificity of binding will enable targeted drug delivery to TNBC cells in the future as well. Due to the efficacy ... "100 inspiring Black scientists in America". crosstalk.cell.com. Retrieved 2020-06-26. "BOARD OF DIRECTORS". bmes.org. Archived ...
"Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes". Proceedings of the National Academy of ... The magnocellular neurosecretory cells that make oxytocin are adjacent to magnocellular neurosecretory cells that make ... Kukucka MA (1993-04-18). Mechanisms by which hypoxia augments Leydig cell viability and differentiated cell function in vitro ( ... Cell. 159 (2): 295-305. doi:10.1016/j.cell.2014.09.020. PMC 4206218. PMID 25303526. Marie-Therese Walsh (2014-10-09). ""Love ...
"PAX4 enhances beta-cell differentiation of human embryonic stem cells". PLOS ONE. 3 (3): e1783. Bibcode:2008PLoSO...3.1783L. ... "Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells". Nat. Biotechnol. 24 (11): 1392- ... including insulin-producing β-cells and glucagon-producing α-cells. Pdx1 is necessary for β-cell maturation: developing β-cells ... 2002). "Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta ...
"Phosphorylation Dynamics during Early Differentiation of Human Embryonic Stem Cells". Cell Stem Cell. 5 (2): 214-226. doi: ... Cell Systems. 9 (4): 366-374.e5. doi:10.1016/j.cels.2019.08.005. PMC 6838672. PMID 31521607. Van Hoof, Dennis; Muñoz, Javier; ... 10.1016/j.stem.2009.05.021. PMID 19664995. Giansanti, Piero; Tsiatsiani, Liana; Low, Teck Yew; Heck, Albert J. R. (2016). "Six ... Molecular Cell. 63 (1): 135-145. doi:10.1016/j.molcel.2016.05.016. PMID 27320199. "Een moleculaire rattenkoning slaat groot ...
Examples of stem and progenitor cells include:[citation needed] Radial glial cells (embryonic neural stem cells) that give rise ... Mesenchymal stem cells (adult stem cells) from the bone marrow that give rise to stromal cells, fat cells, and types of bone ... Hematopoietic stem cells (adult stem cells) from the bone marrow that give rise to red blood cells, white blood cells, and ... promotes embryonic stem cell differentiation and the self-renewal of somatic stem cells. The problem, of course, is that the ...
"Fibrochondrogenesis in two embryonic stem cell lines: effects of differentiation timelines". Stem Cells. 26 (2): 422-430. doi: ... specifically human embryonic stem cells. Utilization of these cells as curative cartilage replacement materials on the cellular ... Stem Cells and Development. 18 (2): 283-92. doi:10.1089/scd.2008.0024. ISSN 1547-3287. PMC 3132948. PMID 18454697. Hoben GM, ... shown potential as a means to produce therapeutic cellular biomaterials via tissue engineering and manipulation of stem cells, ...
"Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers". Cell. 145 (6): 875-889. doi:10.1016/j. ... causing the embryonic stem cells to select their fate. The endoderm is one of the germ layers formed during animal embryonic ... These transcription factors cause the pluripotent mouse embryonic stem cells to select a germ layer fate. Sox2 promotes ... Through cell signaling cascades and interactions with the ectodermal and endodermal cells, the mesodermal cells begin the ...
"MicroRNA dynamics during human embryonic stem cell differentiation to pancreatic endoderm". Gene. 574 (2): 359-370. doi:10.1016 ... sRNA-seq Analysis of Human Embryonic Stem Cells". Stem Cells. 32 (9): 2360-2372. doi:10.1002/stem.1739. PMID 24805944. S2CID ... "sRNA-seq Analysis of Human Embryonic Stem Cells and Definitive Endoderm Reveals Differentially Expressed MicroRNAs and Novel ... of melanoma autologous tumor cell lines used as the source of tumor associated antigens in patient-specific dendritic cell ...
Trophoblast differentiation in embryoid bodies derived from human embryonic stem cells. Endocrinology, 145, 1517-1524. Pidoux, ... An in vitro model of early human embryogenesis (human embryonic stem cells (hESCs)) has demonstrated that hCG promotes cell ... Gallego, M. et al (2010). The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell ... Stem Cell Research & Therapy, 1, 1-13 Carr, B., MacDonald, P., Simpson, E. (1982). The role of lipoproteins in the regulation ...
... and in vitro differentiation of canine embryonic stem cells". Stem Cells. 26 (2): 465-73. doi:10.1634/stemcells.2007-0640. PMID ... Cell Stem Cell. 8 (4): 376-88. doi:10.1016/j.stem.2011.03.001. PMC 3090650. PMID 21474102. Olivieri F, Lazzarini R, Recchioni R ... Tsai ZY, Chou CH, Lu CY, Singh S, Yu SL, Li SS (Aug 2011). "Proteomic comparison of human embryonic stem cells with their ... "Identification of microRNAs regulated by activin A in human embryonic stem cells". Journal of Cellular Biochemistry. 109 (1): ...
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"Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation". Genome Research. 18 (9): 1433-1445. doi: ... "Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells". Cell Stem Cell. 18 (5): 637-652. ... "EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression". Developmental ... doi:10.1016/j.stem.2016.01.024. ISSN 1934-5909. PMID 26996597. (Articles with short description, Short description is different ...
... and in vitro differentiation of canine embryonic stem cells". Stem Cells. 26 (2): 465-473. doi:10.1634/stemcells.2007-0640. ... She showed that cells within the bone marrow send signals to stem cells which determine whether transplantations are successful ... Prior to the work of Torok-Storb, it was assumed that bone marrow stromal cells could be derived from Hematopoietic stem cells ... Her research identified the interactions between the stem cells in blood and the supportive cells in bone marrow, enabling ...
"Differentiation of human embryonic stem cells to cardiomyocytes", published 22 July 2002 WO patent 2004110912A2, Steinhardt, ... Mummery is also the founding editor of Stem Cell Reports; is on the editorial Board of Cell Stem Cells, Stem Cells, Current ... embryonic) stem cells as models. In 2007, Mummery was a visiting professor jointly at the Harvard Stem Cell Institute (HSCI) ... "Differentiation of human embryonic stem cells to cardiomyocytes", published 28 December 2005 WO patent 2006066320A1, Mummery, ...
Embryonic stem cell proliferation was unaffected by the loss of either HDAC1 or HDAC2 but the differentiation of embryonic stem ... LIF inhibits cell differentiation, and its removal allows the cell lines to go through cell differentiation. The cell lines ... In embryonic stem cells, DNMT1 depletion within the undifferentiated progenitor cell compartment led to cell cycle arrest, ... of these epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) ...
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"Competitive Interactions Eliminate Unfit Embryonic Stem Cells at the Onset of Differentiation". Developmental Cell. 26 (1): 19- ... Cell competition is a phenomenon first described in Drosophila where mosaic Minute mutant cells (affecting ribosomal proteins) ... This means that two cells in exactly identical regulatory states will exhibit different mRNA contents. The cell population ... Kesavan, Gokul; Hans, Stefan; Brand, Michael (2019). "Cell-fate plasticity, adhesion and cell sorting complementarily establish ...
Deletion of KDM1A impairs the growth and differentiation of embryonic stem cells. Deletion of the mouse ortholog, Kdm1a, has an ... By this method, the loss of function shows a dependence of both hematopoietic stem and progenitor cells on LSD1 for self- ... The interaction of LSD1 with the transcription factor GFI1B is particularly important for regulating the balance in stem cells ... doi:10.1016/j.cell.2009.05.050. PMID 19703393. Zhou A, Lin K, Zhang S, Chen Y, Zhang N, Xue J, et al. (September 2016). " ...
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To confer pluripotency in an embryonic stem cell, factors inhibit Xist transcription. These factors also upregulate ... Cellular differentiation Xist X-inactivation Barr body GRCh38: Ensembl release 89: ENSG00000270641 - Ensembl, May 2017 "Human ... link X reactivation and stem cell reprogramming". Mol. Cell. 52 (6): 805-18. doi:10.1016/j.molcel.2013.10.023. PMC 3950835. ... Alternately, it may be necessary to study cells closer to the X inactivation stage rather than older cells in order to ...
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