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*  EEF2
... of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2". J. ... This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for ... Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. ... Kaneda Y, Yoshida MC, Kohno K, Uchida T, Okada Y (Jul 1984). "Chromosomal assignment of the gene for human elongation factor 2 ...
*  POLR2A
Pan G, Aso T, Greenblatt J (September 1997). "Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase ... Jeang KT (1998). "Tat, Tat-associated kinase, and transcription". J. Biomed. Sci. 5 (1): 24-7. doi:10.1007/BF02253352. PMID ... Conaway RC, Kong SE, Conaway JW (August 2003). "TFIIS and GreB: two like-minded transcription elongation factors with sticky ... a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 ...
*  Elongation factor 2 kinase
Other names in common use include Ca/CaM-kinase III, calmodulin-dependent protein kinase III, CaM kinase III, eEF2 kinase, eEF- ... protein-serine/threonine kinases). The systematic name of this enzyme class is "ATP:[elongation factor 2] phosphotransferase". ... "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its ... In enzymology, an elongation factor 2 kinase (EC 2.7.11.20) is an enzyme that catalyzes the chemical reaction: ATP + [ ...
*  CREB1
Wang X, Li W, Williams M, Terada N, Alessi DR, Proud CG (Aug 2001). "Regulation of elongation factor 2 kinase by p90(RSK1) and ... "Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not ... This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein ... Kim J, Jia L, Stallcup MR, Coetzee GA (Feb 2005). "The role of protein kinase A pathway and cAMP responsive element-binding ...
*  MAPKAPK5
Knebel A, Haydon CE, Morrice N, Cohen P (2002). "Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB ... activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase". Biochem. Biophys. Res. ... MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this ... "Entrez Gene: MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5". de Carvalho MG, McCormack AL, Olson E, et ...
*  EEF2K
"Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its ... "Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase". Proceedings of the ... also known as calmodulin-dependent protein kinase III (CAMKIII) and calcium/calmodulin-dependent eukaryotic elongation factor 2 ... It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of eEF-2K is ...
*  RPS6KA5
2001). "Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3 ... "Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase". EMBO J. England. 20 (16): 4370-9. doi:10.1093/emboj/ ... coupled receptor agonists requires both extracellular-signal-regulated kinase and p38 mitogen-activated protein kinase". ... Ribosomal protein S6 kinase alpha-5 is an enzyme that in humans is encoded by the RPS6KA5 gene. RPS6KA5 has been shown to ...
*  Eukaryotic translation initiation factor 4 gamma 1
"Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in ... "The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine ... "The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the ... "The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the ...
*  EIF4EBP1
"Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in ... "Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo". Mol. ... kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes". J. Biol. ... "Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin- ...
*  EIF4E
"Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in ... "Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of ... Eukaryotic initiation factors Eukaryotic initiation factor 4F (eIF4F) GRCh38: Ensembl release 89: ENSG00000151247 - Ensembl, ... "The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the ...
*  EIF4A1
"Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in ... Cuesta R, Xi Q, Schneider RJ (2000). "Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation ... "The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13". Genomics. 53 (2): 248-50. ... Eukaryotic initiation factor 4A-I is a protein that in humans is encoded by the EIF4A1 gene. EIF4A1 has been shown to interact ...
*  MAPK11
This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ... Knebel A, Haydon CE, Morrice N, Cohen P (2002). "Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB ... kinase isoforms by the MAP kinase kinases MKK3 and MKK6". J. Biol. Chem. 273 (3): 1741-8. doi:10.1074/jbc.273.3.1741. PMID ... This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and ...
*  Protein kinase, AMP-activated, alpha 1
2003). "Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of ... 2001). "Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase". EMBO J. 20 (16): 4370-9. doi:10.1093/emboj/ ... 2001). "Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin- ... 1996). "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the ...
*  MAPKAPK3
Knebel A, Haydon CE, Morrice N, Cohen P (2002). "Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB ... This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known ... kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase". J Biol Chem. 271 (14): 8488-92. doi:10.1074/jbc. ... kinase-activated protein kinase, is targeted by three MAP kinase pathways". Mol. Cell. Biol. 16 (12): 6687-97. PMC 231671 . ...
*  Phenoptosis
EF2 kinase - Blocks phosphorylation of elongation factor 2 thus blocking protein synthesis. Glucocorticoid regulation - A ... 60 (2): 101-121. doi:10.1007/BF00569695. PMID 7042533. Yun, A; Lee, P.; Doux, J. (2006). "Osteoarthritis: An example of ... marsupial mice - Males die 2 weeks after reproducing from an overabundance of their own pheromones. Salmon - Die soon after ...
*  EEF1B2
Sheu GT, Traugh JA (Jan 1999). "A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII". ... Elongation factor 1-beta is a protein that in humans is encoded by the EEF1B2 gene. This gene encodes a translation elongation ... "Expression of recombinant elongation factor 1 beta from rabbit in Escherichia coli. Phosphorylation by casein kinase II". ... "Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B". Structure. 12 (9): ...
*  Cyclin-dependent kinase 9
This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA ... Lee DK, Duan HO, Chang C (March 2001). "Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the ... Cyclin-dependent kinase 9 or CDK9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a ... CDK9 cyclin-dependent kinase 9 (CDC2-related kinase)". MacLachlan TK, Sang N, De Luca A, Puri PL, Levrero M, Giordano A (1998 ...
*  Management of hair loss
... hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase ... Adenosine stimulates dermal papillae in vitro to induce IGF-1, along with fibroblast growth factors FGF7, FGF-2 and VEGF. β- ... "Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells". PLoS ONE ... Okajima, K.; Harada, N. (2008). "Promotion of insulin-like growth factor-I production by sensory neuron stimulation; molecular ...
*  Eukaryotic translation elongation factor 1 alpha 1
"Protein kinase C delta-specific phosphorylation of the elongation factor eEF-alpha and an eEF-1 alpha peptide at threonine 431 ... an elongation factor protein, a GTPase, and an actin bundling protein. As an elongation factor, it is known to mediate the ... EEF1A1 eukaryotic translation elongation factor 1 alpha 1". Becker M, Kuhse J, Kirsch J (Dec 2013). "Effects of two elongation ... Elongation factor 1-alpha 1 (eEF1a1) is a protein that in humans is encoded by the EEF1A1 gene. This gene encodes an isoform of ...
*  EEF1D
Sheu GT, Traugh JA (Jan 1999). "A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII". ... "Elongation factor 1 beta of artemia: localization of functional sites and homology to elongation factor 1 delta". Biochimica et ... Chang YW, Traugh JA (Nov 1997). "Phosphorylation of elongation factor 1 and ribosomal protein S6 by multipotential S6 kinase ... "Phosphorylation of elongation factor 1 (EF-1) and valyl-tRNA synthetase by protein kinase C and stimulation of EF-1 activity". ...
*  Epstein-Barr virus nuclear antigen 2
EBNA2 requires C-promoter binding factor 1 (CBF1) to aid in binding to its cis-responsive DNA element, the C promoter (Cp). ... Regulation of transcription initiation and elongation by EBNA 2 is done part through cyclin-dependent kinase 9 (CDK9) dependent ... EBNA2 also interacts with the human homolog of the yeast transcription factor (SNF5 hSNF5/Ini1) as it coelutes with both hSNF5/ ... EBNA2 has an acidic activation domain, which can interact with many different general transcription factors and co-activators. ...
*  EEF1G
Sheu GT, Traugh JA (1999). "A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII". Mol ... Elongation factor 1-gamma is a protein that in humans is encoded by the EEF1G gene. This gene encodes a subunit of the ... "Recombinant subunits of mammalian elongation factor 1 expressed in Escherichia coli. Subunit interactions, elongation activity ... Kim JE, Kim KH, Lee SW, Seol W, Shiba K, Kim S (2000). "An elongation factor-associating domain is inserted into human ...
*  Rck-2
"Circadian clock regulation of mRNA translation through eukaryotic elongation factor eEF-2". PNAS. Galagan, James. "The genome ... which is an elongation factor that plays a major role in translation. Phosphorylation of eEF-2 has an inhibitory effect on the ... Rck-2 is a gene that plays a major role in clock control of translation. Rck-2 protein is a kinase and is rhythmically ... Rck-2 is largely studied in Neurospora crassa but has significant homology to humans. Knockout strains have been produced in ...
*  SUPT16H
Orphanides G, Wu WH, Lane WS, Hampsey M, Reinberg D (1999). "The chromatin-specific transcription elongation factor FACT ... "A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1". Mol Cell. 7 (2): 283-92. doi:10.1016/S1097 ... a factor that facilitates transcript elongation through nucleosomes". Cell. 92 (1): 105-16. doi:10.1016/S0092-8674(00)80903-4. ... "Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68". Genes Cells ...
*  GTF2H4
Li XY, Green MR (1998). "The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor". Genes Dev. ... Ping YH, Rana TM (1999). "Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes ... Drapkin R, Le Roy G, Cho H, Akoulitchev S, Reinberg D (1996). "Human cyclin-dependent kinase-activating kinase exists in three ... General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene. GTF2H4 has been shown to ...
*  CDC25C
"The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1". Mol. Cell. ... Booher RN, Holman PS, Fattaey A (1997). "Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity ... 1993). "Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase". FEBS Lett. 318 (3): ... 1994). "Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior ...
*  ANKRD24
... protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), nuclear factor NF-kappa-B p105 subunit (NFKB1), cholest-5- ... eukaryotic translation elongation factor 1-alpha 1 (EEF1A1), unc-119 homolog A (UNC119), replication timing regulatory factor 1 ... "Phyre 2 Results for My_protein". www.sbg.bio.ic.ac.uk. Retrieved 2016-04-27. "SAPS submission on ANKRD24". Biology WorkBench. " ... ene-3β,7α-diol 3β-dehydrogenase (HSD3B7), lethal giant larvae homolog 2 (L2GL2), and glucocorticoid induced 1 (GLC)CI1. No ...