Godaux E, Mettens P, Cheron G (1993). "Differential effect of injections of kainic acid into the prepositus and the vestibular ... Cheron, G.; Godaux, E. (1 December 1987). "Disabling of the oculomotor neural integrator by kainic acid injections in the ... Cheron G, Godaux E (1987). "Disabling of the oculomotor neural integrator by kainic acid injections in the prepositus- ... Cheron G, Godaux E (1987). "Disabling of the oculomotor neural integrator by kainic acid injections in the prepositus- ...
AMPA Domoic acid Kainic acid NMDA Quinolinic acid Quisqualic acid Tetrazolylglycine Acetylcholine receptor agonists are drugs ... Many other drugs may cause convulsions as a side effect at high doses (e.g. bupropion, tramadol, pethidine, dextropropoxyphene ... Anatoxin-a Pilocarpine Camphor injections for psychiatric treatment were inefficient and were replaced by pentylenetetrazol. ... For example, kainic acid can lead to status epilepticus in animals as it is a cyclic analog of l-glutamate and an agonist for ...
... is commonly injected into laboratory animal models to study the effects of experimental ablation. Kainic acid is a ... injection of kainic acid or administration of an electrical shock. In 2019, Chekan et al were able to use bioinformatic tools ... taking prekainic acid to the final kainic acid. KabC was also able to produce another kainic acid isomer, kainic acid lactone. ... Kainic acid, or kainate, is an acid that naturally occurs in some seaweed. Kainic acid is a potent neuroexcitatory amino acid ...
... administration have shown a neuroprotective effect on hippocampal neurons in seizure models induced by kainic acid. The proper ... In general, progesterone administration is anticonvulsant, as supported by experiments in laboratory animals, where injection ... The use of hormone replacement therapy (HRT), to lessen the effects of menopause, has shown severe negative effects on the ... The review did note however that important clinical effects could not be ruled out due to the small and under powered nature of ...
It is well characterized that injection of kainic acid can induce seizures, including temporal lobe epilepsy months after ... The main side effects of over-activation of AMPA receptors are seizure and neuron death. There is limited in vivo research on ... They have five subunits, divided into two main families: GluK1,2, and GluK5,6,7. An endogenous ligand, either kainic acid or ... Consistent with these findings, transgenic mice with knocked out GluK1 have reduced seizures after treatment with kainic acid. ...
... or kainic acid. The dual effect of seletracetam is an overall decrease in the amount of Ca2+ influx in the cell during an ... doses as low as 0.07 mg/kg intraperitoneal injection (i.p.), and ED50 of 0.31 mg/kg i.p. were effective. Occurrence of ... The typical dosage is 0.03-10 mg/kg per day (up to 0.6g per day). Seletracetam's anti-epileptic effects are due to its high ... This was demonstrated by its effect on Strasbourg genetic absence epilepsy rats (GAERS). This model had an ED50 of 0.15 mg/kg i ...
Kainic acid, used to model TLE and related scleroses, affects primarily the mossy fiber synapses in CA3. It is thought that at ... Damaging effects of stress in these neurons are thought to be related to expression of brain-derived neurotrophic factor (BDNF ... Injection of tetanus toxin into neonatal rats has shown that growth of apical dendrites occurs normally during signal ... These receptors are most dense in sectors CA3 and CA2 of the hippocampus, where nanomolar (nM) concentrations of kainic acid ...
Coyle, Joseph T.; Schwarcz, Robert (1976). "Lesion of Striatal Neurons with Kainic Acid Provides a Model for Huntington's ... "Extrafusal and Intrafusal Muscle Effects in Experimental Botulinum Toxin-A Injection". Muscle & Nerve. 19 (4): 488-96. doi: ... The resultant effect of this toxicity can be reduced brain energy metabolism and function. Importantly, the toxic effects of ... Among the known effects of ethanol exposure are both transient and lasting consequences. Some of the lasting effects include ...
Similar results are obtained after injection of kainic acid, an analog of glutamic acid which causes a severe neurodegenerative ... Do Carmo, S; Jacomy, H; Talbot, PJ; Rassart, E (8 October 2008). "Neuroprotective effect of apolipoprotein D against human ... Tg mice treated with kainic acid show a significant reduction of inflammatory responses and a much stronger protection against ... Other ApoD ligands include E-3-methyl-2-hexenoïc acid, a scent molecule present in body odor secretions; retinoic acid, which ...