Differences in effector binding distinguish RhoA amongst other related Ras homologs GTPases. Integrins can modulate RhoA ... Vignal E, Blangy A, Martin M, Gauthier-Rouvière C, Fort P (December 2001). "Kinectin is a key effector of RhoG microtubule- ... Cell shape acts as the primary mechanical cue that drives RhoA activity and downstream effector ROCK activity to control stem ... Zhang B, Chernoff J, Zheng Y (April 1998). "Interaction of Rac1 with GTPase-activating proteins and putative effectors. A ...

"Fungal Effectors and Plant Susceptibility". Annual Review of Plant Biology. Annual Reviews. 66 (1): 513-545. doi:10.1146/ ...

Bartok, Beatrix; Firestein, Gary S. (2010). "Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis". ...

Zheng, L; Schickling O; Peter M E; Lenardo M J (August 2001). "The death effector domain-associated factor plays distinct ... 1997). "CASH, a novel caspase homologue with death effector domains". J. Biol. Chem. 272 (32): 19641-4. doi:10.1074/jbc.272.32. ... a novel caspase homologue with death effector domains". J. Biol. Chem. UNITED STATES. 272 (32): 19641-4. doi:10.1074/jbc.272.32 ...

This particular protein domain can be referred to as a Rho GTPase-activating protein (GAP). YopE is an effector protein of the ... Stebbins CE, Galán JE (2000). "Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP ...

Second, the activated G-protein produces a primary effector. Third, the primary effect stimulates the second messenger ... The G-protein coupled receptors for the PIP2 messenger system produces two effectors, phospholipase C (PLC) and ... Phosphoinositide 3-kinase (PI3K) as an effector phosphorylates phosphatidylinositol bisphosphate (PIP2) to produce ... phosphoinositide 3-kinase (PI3K). PLC as an effector produces two different second messengers, inositol triphosphate (IP3) and ...

TIGAR removes the allosteric effector, Fru-2,6-P2., therefore the activator does not enhance the affinity of the enzyme (PFK1) ...

Renin is the main effector of the juxtaglomerular baroreceptors. Renin is secreted from granules in the JG cells, and once in ...

January 2011). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids ... December 2009). "Breaking the code of DNA binding specificity of TAL-type III effectors". Science. 326 (5959): 1509-12. Bibcode ... Moscou MJ, Bogdanove AJ (December 2009). "A simple cipher governs DNA recognition by TAL effectors". Science. 326 (5959): 1501 ... October 2010). "Targeting DNA double-strand breaks with TAL effector nucleases". Genetics. 186 (2): 757-61. doi:10.1534/ ...

Vidarsson G, Dekkers G, Rispens T (2014). "IgG subclasses and allotypes: from structure to effector functions". Frontiers in ...

Vidarsson, Gestur; Dekkers, Gillian; Rispens, Theo (2014). "IgG subclasses and allotypes: from structure to effector functions ... Vidarsson, Gestur; Dekkers, Gillian; Rispens, Theo (2014). "IgG subclasses and allotypes: from structure to effector functions ... from structure to effector functions". Frontiers in Immunology. 5: 520. doi:10.3389/fimmu.2014.00520. ISSN 1664-3224. PMC ...

Galeotti C, Kaveri SV, Bayry J (December 2017). "IVIG-mediated effector functions in autoimmune and inflammatory diseases". ...

One recognition site acts as the target for cleavage, while the other acts as an allosteric effector that speeds up or improves ... Other artificial restriction enzymes are based on the DNA binding domain of TAL effectors. In 2013, a new technology CRISPR- ... October 2010). "Targeting DNA double-strand breaks with TAL effector nucleases". Genetics. 186 (2): 757-61. doi:10.1534/ ... hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359-72. doi:10.1093/ ...

TAL effector nucleases (TALENs) are particularly interesting because TAL effectors appear to be very simple to engineer and ... August 2010). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids ... July 2010). "Targeting DNA Double-Strand Breaks with TAL Effector Nucleases". Genetics. 186 (2): 757-761. doi:10.1534/genetics. ... Moscou MJ, Bogdanove AJ (December 2009). "A simple cipher governs DNA recognition by TAL effectors". Science. 326 (5959): 1501 ...

In season 2013/2014 he played for Effector Kielce. In 2014 he went to AZS Politechnika Warszawska. CEV Champions League 2002/ ... Effector Kielce players, Projekt Warsaw players, Warta Zawiercie (volleyball) players, All stub articles, Polish volleyball ...

He is an expert in a variety of topics ranging from organic synthesis, bioorganic chemistry, catalytic sensor/effector agents, ... Jacob, Fiona H. Fry and Claus (30 November 2006). "Sensor/Effector Drug Design with Potential Relevance to Cancer". Current ... Jacob main scientific contributions are Reactive Sulfur Species (2002), the Sensor / Effector catalysts in drug design (around ...

The effector domain may be a transcriptional activator (A) or repressor (R), a methylation domain (M) or a nuclease (N). ... July 2010). "TAL Effector Nucleases Create Targeted DNA Double-strand Breaks". Genetics. 186 (2): 757-761. doi:10.1534/genetics ... While initial studies with another DNA-binding domain from bacterial TAL effectors show promise, it remains to be seen whether ... August 2010). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids ...

Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer. Cell 165, 1092-1105 (2016). Kryczek, I. et al. IL- ... Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nature immunology 17, ... Human TH17 Cells Are Long-Lived Effector Memory Cells. Sci Transl Med 3, 104ra100, doi:10.1126/scitranslmed.3002949 (2011). Zou ...

... neutrophils and other effector cells from the blood to sites of infection or tissue damage. Certain inflammatory chemokines ... and effector function". The Journal of Allergy and Clinical Immunology. 111 (6): 1185-99, quiz 1200. doi:10.1067/mai.2003.1594 ...

NUMB is the most studied downstream effector of RBM10. RBM10 promotes the skipping of exon 9 of the NUMB transcript, producing ...

Vidarsson G, Dekkers G, Rispens T (2014-10-20). "IgG subclasses and allotypes: from structure to effector functions". Frontiers ...

There are four families of engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector ... hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359-72. doi:10.1093/ ... "Targeting DNA double-strand breaks with TAL effector nucleases". Genetics. 186 (2): 757-61. doi:10.1534/genetics.110.120717. ...

There are four families of engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector ... hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359-72. doi:10.1093/ ... "Targeting DNA double-strand breaks with TAL effector nucleases". Genetics. 186 (2): 757-61. doi:10.1534/genetics.110.120717. ...

The Cas9 protein binds to a combined form of crRNA and tracrRNA forming an effector complex. This act as guide RNA for cas9 ... Nishimasu, Hiroshi; Nureki, Osamu (2017). "Structures and mechanisms of CRISPR RNA-guided effector nucleases". Current Opinion ... which all together known as effector complex. With the modifications in the crRNA sequences of the guide RNA, the binding ...

This enzyme has at least one effector, Bile salt. Blaner WS, Das SR, Gouras P, Flood MT (1987). "Hydrolysis of 11-cis- and all- ...

Penchev spent the 2012/2013 season in Effector Kielce. In 2013, he moved to Asseco Resovia and signed a two-year contract. In ... Effector Kielce players, Resovia (volleyball) players, Skra Bełchatów players, Projekt Warsaw players, Warta Zawiercie ( ...

There are four families of engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector ... hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359-72. doi:10.1093/ ... "Targeting DNA double-strand breaks with TAL effector nucleases". Genetics. 186 (2): 757-61. doi:10.1534/genetics.110.120717. ...

After the memory B cell recognizes the antigen it presents the peptide: MHC II complex to nearby effector T cells. That leads ... These cells were named memory effector T cells (TEM). After repeated stimulation they produce large amounts of IFN-γ, IL-4 and ... After the primary immune response has disappeared, the effector cells of the immune response are eliminated. However, ... "Two subsets of memory T lymphocytes with distinct homing potentials and effector functions." Nature 401.6754 (1999): 708. ...

Sitnik TS, Avaeva SM (January 2007). "Binding of substrate at the effector site of pyrophosphatase increases the rate of its ... Rodina EV, Vorobyeva NN, Kurilova SA, Belenikin MS, Fedorova NV, Nazarova TI (January 2007). "ATP as effector of inorganic ... Several studies have also identified additional substrates that can act as allosteric effectors. In particular, the binding of ... pyrophosphate (PPi) to the effector site of inorganic pyrophosphatase increases its rate of hydrolysis at the active site. ATP ...

... whereas in effector T cells, PKC-θ is present. As a result of co-stimulation by CD28 and TCR, PKC-θ is sumoylated by SUMO1 ... PKC-θ promotes inflammation in effector T cells. PKC-θ plays a role in the activation of ILC2 and contribute to the ...