... receptor PTTH - Metamorphosis Initiator hormone Ecdybase, The Ecdysone Handbook - a free online ecdysteroids database ... Ecdysone and other ecdysteroids also appear in many plants mostly as a protection agent (toxins or antifeedants) against ... Ecdysone is a[clarification needed] prohormone of the major insect molting hormone 20-hydroxyecdysone, secreted from the ... Insect molting hormones (ecdysone and its homologues) are generally called ecdysteroids. Ecdysteroids act as moulting hormones ...
... s have two main fields of application: Gene switches - ecdysone receptor-controlled transgenes for controlled ... and mediate the binding of the heterodimer to these ecdysone response elements (ECREs) in the promoters of ecdysone-responsive ... "The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ... The ecdysone receptor is a nuclear receptor found in arthropods, where it controls development and contributes to other ...
In enzymology, an ecdysone oxidase (EC 1.1.3.16) is an enzyme that catalyzes the chemical reaction ecdysone + O2 ⇌ {\ ... The systematic name of this enzyme class is ecdysone:oxygen 3-oxidoreductase. This enzyme might also be called beta-ecdysone ... Koolman J, Karlson P (1975). "Ecdysone Oxidase, an enzyme from the blowfly Calliphora erythrocephala (Meigen)". Hoppe-Seyler's ... displaystyle \rightleftharpoons } 3-dehydroecdysone + H2O2 Thus, the two substrates of this enzyme are ecdysone and O2, whereas ...
... (EC 1.14.99.22) is an enzyme that catalyzes the chemical reaction ecdysone + AH2 + O2 ⇌ {\ ... and ecdysone 20-hydroxylase. Johnson P, Rees HH (1977). "The mechanism of C-20 hydroxylation of alpha-ecdysone in the desert ... The systematic name of this enzyme class is ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating). Like other genes ... Gilbert LI; Bollenbacher, WE; Cooper, DY; Schleyer, H; Wielgus, JJ; Gilbert, LI (1979). "Ecdysone 20-monooxygenase: ...
Other names in common use include acyl-CoA:ecdysone acyltransferase, and fatty acyl-CoA:ecdysone acyltransferase. Slinger AJ, ... ecdysone palmitate Thus, the two substrates of this enzyme are palmitoyl-CoA and ecdysone, whereas its two products are CoA and ... In enzymology, an ecdysone O-acyltransferase (EC 2.3.1.139) is an enzyme that catalyzes the chemical reaction palmitoyl-CoA + ... The systematic name of this enzyme class is palmitoyl-CoA:ecdysone palmitoyltransferase. ...
Ecdysone and 20-hydroxyecdysone regulate larval molts, onset of puparium formation, and metamorphosis. Being that these ... Indeed, the main receptor of these hormone signals - the ecdysone receptor - is an intracellular protein. 20-Hydroxyecdysone ... Graham LD (June 2002). "Ecdysone-controlled expression of transgenes". Expert Opinion on Biological Therapy. 2 (5): 525-35. doi ... In arthropods, 20-hydroxyecdysone acts through the ecdysone receptor. Although mammals lack this receptor, 20-hydroxyecdysone ...
It is thought that ecdysone induced apoptosis is regulated by the Caspase Dronc. This protein conducts Rpc- and Grim-induced ... Kilpatrick ZE, Cakouros D, Kumar S (March 2005). "Ecdysone-mediated up-regulation of the effector caspase DRICE is required for ... Dorstyn L, Colussi PA, Quinn LM, Richardson H, Kumar S (April 1999). "DRONC, an ecdysone-inducible Drosophila caspase". ... For example, a higher concentration of ecdysones (common during the metamorphosis) leads cuticle deposition and larval moults, ...
Its counterpart in insects is ecdysone. The presence of these ubiquitous steroids in a wide range of animals suggest that sex ...
Ecdysone steroids have also been found. Some species are cyanogenic.[citation needed] The Menispermaceae have been used in ...
These are switched by the hormone ecdysone. The dry-season forms are usually more cryptic, perhaps offering better camouflage ...
In the development stage, as long as there is enough JH, the ecdysone promotes larva-to-larva molts. With lower amounts of JH, ... There is a complex interaction between JH, the hormone ecdysone and vitellogenin. ... ecdysone promotes pupation. Complete absence of JH results in formation of the adult. In adult honey bees, JH and Vitellogenin ...
Hill, R. J.; Billas, I. M. L.; Bonneton, F. O.; Graham, L. D.; Lawrence, M. C. (2013). "Ecdysone Receptors: From the Ashburner ... He went on to demonstrate the effects of various stimuli, especially heat-shock and ecdysone, on puffing at specific loci, and ... he established the existence of a cascade of genetic controls in the post-larval development triggered by ecdysone. The ...
Kaplanis, J. N.; Thompson, M. J.; Robbins, W. E.; Bryce, B. M. (22 September 1967). "Insect Hormones: Alpha Ecdysone and 20- ... Two major insect moulting hormones, alpha ecdysone and 20-hydroxyecdysone, are found in bracken. These cause uncontrollable, ...
Ecdysone receptor Ecdybase, The Ecdysone Handbook - a free online ecdysteroids database de Loof A (2006). "Ecdysteroids: the ... Krishnakumaran A, Schneiderman HA (December 1970). "Control of molting in mandibulate and chelicerate arthropods by ecdysones ... examples of ecdysteroids include ecdysone, ecdysterone, turkesterone and 2-deoxyecdysone. These compounds are synthesized in ...
He showed that a hormone from the brain activated the prothoracic glands to release the moulting hormone ecdysone. When the ... Williams was the first to isolate juvenile hormone and ecdysone. With his students he studied cocoon-spinning behavior and the ...
The shadow gene (Cyp315a1) product produces ecdysone from 2-deoxyecdysone. The shade gene (Cyp314a1) codes for an Ecdysone 20- ... Namiki T, Niwa R, Sakudoh T, Shirai K, Takeuchi H, Kataoka H (2005). "Cytochrome 450 CYP307A1/Spook: A regulator for ecdysone ... All of the genes code for cytochrome P450 enzymes in the ecdysteroidogenic pathway (biosynthesis of ecdysone from cholesterol ... monooxygenase responsible for adding a hydroxyl group to the 20C-position of ecdysone to make 20-hydroxyecdysone, the final ...
Ponesterone, which is similar to insect's moulting hormone ecdysone, is obtained from this plant. It was the first ecdysone ...
... and insect's receptor Ecdysone (EcR). In 2004 a comparative analysis of the primary sequences lead to the partition of the ... "Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor". Nature. 426 (6962): 91-96. Bibcode: ...
In many species it is initiated by an increase in the hormone ecdysone. This hormone causes: apolysis - the separation of the ...
They have an ectodermal origin and secrete ecdysteroids, such as ecdysone and 20-hydroxyecdysone. The chemical formula of ...
Ecdysone-induced protein 75 (E75) inhibits clk expression and tim-dependently activates per transcription. All of these ...
It is an agonist of the ecdysone receptor that causes premature molting in larvae. It is primarily used against caterpillar ...
Very detailed studies have been done on JH, JH acid, ecdysone, and JH titers have been done in precisely timed larvae of ... A very similar timing of peaks of JH esterase and ecdysone has been observed in Galleria mellonella. These data are consistent ... Correlations between Juvenile Hormone Esterase-Activity, Ecdysone Titer and Cellular Reprogramming in Galleria Mellonella. J. ... with a classical model for lepidopterans where JH is high at each larval molt, but must rise together with ecdysone prior to ...
Azadirachtin mimics insect hormones called ecdysones that regulate pupation of insects; application of azadirachtin interrupts ...
He examined the role of the hormone ecdysone in the development of the fruit fly. In 1978, Hogness and his group identified the ...
"A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands". Current Biology. 20 (20): ...
2014). "Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells". Cell. 158 ( ...
Triterpenes mimic the insect molting hormone ecdysone, disrupting molting and development and is often lethal. They are usually ...
"A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands". Current Biology. 20 (20): ...
In insects 7-dehydrocholesterol is a precursor for the hormone ecdysone, required for reaching adulthood. It was discovered by ...