Transcription factor E2F2 is a protein that in humans is encoded by the E2F2 gene. The protein encoded by this gene is a member ... "Entrez Gene: E2F2 E2F transcription factor 2". Crowley TE, Kaine EM, Yoshida M, Nandi A, Wolgemuth DJ (August 2002). " ... Magae J, Wu CL, Illenye S, Harlow E, Heintz NH (1997). "Nuclear localization of DP and E2F transcription factors by ... Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ (2002). "Isolating human transcription factor targets by coupling ...

... has been shown to interact with E2F2, and many transcription factors including GATA1. ENSG00000234507, ENSG00000230678, ... 1997). "Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked ...

E2F1, E2F2, and E2F3A are the three canonical activators of the E2F family of transcription factors. During G2, cyclin F ... Cyclin F interacts with other proteins that are important for centrosomal duplication, gene transcription, and DNA synthesis, ...

The transcription factor family E2F are also thought to be very important in regulating cardiomyocyte proliferation. E2F ... Ebelt H, Zhang Y, Kampke A, Xu J, Sclitt A, Buerke M, Braun T (2008). "E2F2 expression induces proliferation of terminally ... The cessation of the cardiomyocyte cell cycle is believed to be regulated by transcription factors and cyclin dependent kinase ... However, there are various transcription factors and signaling cascades thought to be very important. Cardiomyocytes have been ...

"Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor". Molecular and Cellular Biology ... This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to ... Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member ... Magae J, Wu CL, Illenye S, Harlow E, Heintz NH (Jul 1996). "Nuclear localization of DP and E2F transcription factors by ...

Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. The protein encoded by this gene is a member ... This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially ... Strachan GD, Jordan-Sciutto KL, Rallapalli R, Tuan RS, Hall DJ (February 2003). "The E2F-1 transcription factor is negatively ... "Entrez Gene: E2F1 E2F transcription factor 1". Li CG, Nyman JE, Braithwaite AW, Eccles MR (December 2011). "PAX8 promotes tumor ...

Overexpression of the transcription factor E2F2 is capable of promoting resistance to CDK4/6 inhibition more than just loss of ... human epidermal growth factor receptor 2 (HER2) negative advanced or metastatic breast cancer, in combination with an aromatase ... human epidermal growth factor receptor 2 (HER2) negative locally advanced or metastatic breast cancer either in combination ... Human Epidermal Growth Factor Receptor-2 Negative Advanced Breast Cancer" at ClinicalTrials.gov "NCI Drug Dictionary". National ...

pRb is able to bind to transcription factors in the E2F family and thereby inhibit their function. When pRb is chronically ... factor ARID4A Aryl hydrocarbon receptor BRCA1 BRF1 C-jun C-Raf CDK9 CUTL1 Cyclin A1 Cyclin D1 Cyclin T2 DNMT1 E2F1 E2F2, E4F1 ... The TFIID binds to the TATA box in order to begin the assembly of the TFIIA, recruiting other transcription factors and ... Sutcliffe JE, Cairns CA, McLees A, Allison SJ, Tosh K, White RJ (June 1999). "RNA polymerase III transcription factor IIIB is a ...

Trimarchi JM, Fairchild B, Wen J, Lees JA (Feb 2001). "The E2F6 transcription factor is a component of the mammalian Bmi1- ... RYBP has been shown to interact with: Abl gene, CBX2, Caspase 10, E2F2, E2F3, Mdm2, RING1, and YY1. ENSG00000163602 GRCh38: ... and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404-18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID ... "YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors ...

Drosophila E2F transcription factor - The Interactive Fly Drosophila E2F transcription factor 2 - The Interactive Fly (Articles ... Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G (January 2007). "E2f1, E2f2, ... binds to the E2F1 transcription factor preventing it from interacting with the cell's transcription machinery. In the absence ... E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators ...

The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in ... Okamoto OK, Oba-Shinjo SM, Lopes L, Nagahashi Marie SK (2007). "Expression of HOXC9 and E2F2 are up-regulated in CD133(+) cells ... Transcription factors, All stub articles, Human chromosome 12 gene stubs). ...

... and bind repressive E2F transcription factors E2F4 and E2F5; DP1, DP2 and DP3, dimerization partners of E2F; and MuvB, which is ... The protein complex was thus termed as the Drosophila RBF, E2f2 and Mip (dREAM) complex. Disruption of the dREAM complex ... Compacted DNA at transcription start sites inhibit gene expression by blocking the docking of RNA polymerase. In worms for ... Immunoprecipitation of MuvB factors also revealed association of BMYB. Subsequent immunoprecipitation with BMYB yielded all the ...

Conversely, the B3 element recruits the transcription factor Abf1, albeit B3 is not found at all budding yeast origins and Abf1 ... Lewis PW, Beall EL, Fleischer TC, Georlette D, Link AJ, Botchan MR (December 2004). "Identification of a Drosophila Myb-E2F2/ ... The model postulates that a diffusible, trans-acting factor, a so-called initiator, interacts with a cis-acting DNA element, ... Once recruited to origins, ORC and its co-factors Cdc6 and Cdt1 drive the deposition of the minichromosome maintenance 2-7 ( ...

Most of these targets are not conserved in the human orthologues of these three transcription factors even though they reside ... "miR-24 inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA ...