*Drug development

... such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on ... Council for International Organizations of Medical Sciences Drug design Drug repositioning Generic drug International ... as drug companies use them to justify the prices of their drugs and various advocates for lower drug prices have challenged ... Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified ...

*List of investigational drugs

... may refer to: List of investigational analgesics List of investigational antidepressants List of ... List of investigational hormonal agents List of investigational sexual dysfunction drugs List of investigational sleep drugs. ...

*Expert Opinion on Investigational Drugs

... is a monthly peer-reviewed medical journal covering developments in pharmaceutical ... Expert Opinion on Investigational Drugs was established in 1992 and according to the Journal Citation Reports has a 2014 impact ... The journal publishes articles in the following categories: Reviews Original Research Papers Drug Evaluations Meeting ...

*Investigational New Drug

... (IND) Application Process Center for Drug Evaluation and Research, Food and Drug Administration. ICH ... The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical ... law to investigational use. The FDA runs a medical marijuana IND program (the Compassionate Investigational New Drug program). ... regulates the application of IND drugs to US service personnel. "Investigational New Drug (IND) Application". FDA. Retrieved 7 ...

*List of investigational sleep drugs

This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under ...

*Compassionate Investigational New Drug program

The Compassionate Investigational New Drug program, or Compassionate IND, is a Investigational New Drug program run by the ... against the Food and Drug Administration, the Drug Enforcement Administration, the National Institute on Drug Abuse, the ... The origins of the Compassionate Investigational New Drug Study program began after Robert C. Randall brought a lawsuit ( ... It is administered by the National Institute on Drug Abuse. Closed to new entrants, there are four known surviving patients who ...

*List of investigational sexual dysfunction drugs

This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical ...

*Substrate reduction therapy

Expert Opinion on Investigational Drugs. Expert Opinion Investigational Drugs. 10 (3): 455-66. doi:10.1517/13543784.10.3.455. ... Metabolic therapies under investigation for Late-Onset TSD include treatment with the drug OGT 918 (Zavesca). Platt FM, Neises ...

*Alovudine

"Discontinued drugs in 2005: Anti-infectives". Expert Opinion on Investigational Drugs. 16 (1): 1-10. doi:10.1517/13543784.16. ...

*Tebanicline

Current Opinion in Investigational Drugs. 5 (1): 76-81. ISSN 1472-4472. PMID 14983978. Decker, Michael W.; Meyer, Michael D.; ... Expert Opinion on Investigational Drugs. 10 (10): 1819-1830. doi:10.1517/13543784.10.10.1819. ISSN 1354-3784. PMID 11772288. ... Expert Opinion on Investigational Drugs. 14 (10): 1191-1198. doi:10.1517/13543784.14.10.1191. ISSN 1354-3784. PMID 16185161. ... Sorbera, L.A.; Revel, L.; Leeson, P.; Castañer, J. (2001). "ABT-594". Drugs of the Future. 26 (10): 927. doi:10.1358/dof. ...

*PDE4B

Current Opinion in Investigational Drugs. 10 (11): 1236-42. PMID 19876791. Moustafa F, Feldman SR (May 2014). "A review of ... 2011). Phosphodiesterases as Drug Targets (PDF). Handbook of Experimental Pharmacology. 204. Springer Berlin Heidelberg. doi: ... AN2728, a boron-containing drug candidate that as of 2015 was under development by Anacor Pharmaceuticals for the topical ... to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs". ...

*Pimagedine

... is an investigational drug for the treatment of diabetic nephropathy that is no longer under development as a drug. Pimagedine ... Expert Opinion on Investigational Drugs. 11 (4): 565-574. doi:10.1517/13543784.11.4.565. PMID 11922864. Synvista Therapeutics ... Pimagedine was under development as a drug for kidney diseases by the pharmaceutical company Alteon (now known Synvista ... a collaboration agreement under which Genentech would fund development of pimagedine and would have the rights to sell the drug ...

*Naluzotan

Expert Opinion on Investigational Drugs. 18 (10): 1431-43. doi:10.1517/13543780903184591. PMID 19715445. ... Prof John Kelly (2010). Principles of CNS Drug Development: From Test Tube to Patient. New York: Wiley. ISBN 0-470-51979-7. ... Naluzotan (INN, USAN; PRX-00023) is a serotonergic drug of the phenylpiperazine class that was under investigation by EPIX ... Phenylpiperazine de Paulis T (2007). "Drug evaluation: PRX-00023, a selective 5-HT1A receptor agonist for depression". Curr ...

*Dianicline

Expert Opinion on Investigational Drugs. 2006; 15(2):107-116. Efficacy and Safety of Dianicline Versus Placebo as an Aid to ... Drug development has been discontinued after reporting of unfavourable results during Phase III trials. Cohen C, Bergis OE, ... Dianicline is very similar to the already marketed drug varenicline and it is unclear what advantages it will have over the ... Dianicline (SSR-591,813) is a drug developed by Sanofi-Aventis which acts as a partial agonist at neural nicotinic ...

*Melatonin

Expert Opinion on Investigational Drugs. 15 (4): 367-75. doi:10.1517/13543784.15.4.367. PMID 16548786. Evars, Stefan; Goadsby, ... Melatonin is categorized by the US Food and Drug Administration (FDA) as a dietary supplement, and is sold over-the-counter in ... U.S. Food and Drug Administration. Archived from the original on 12 January 2017. CS1 maint: BOT: original-url status unknown ( ... link) Bebida Beverage Company U.S. Food and Drug Administration March 4, 2015 (Accessed December 8, 2017) "Melatonin". Drugs. ...

*Ceftaroline fosamil

Current Opinion in Investigational Drugs. 9 (2): 201-9. PMID 18246523. "Forest Announces FDA Approval of Teflaro(TM) ( ... No clinical drug-drug interaction studies have been conducted with ceftaroline fosamil. In vitro studies in human liver ... If anemia develops during or after treatment with ceftaroline, drug-induced hemolytic anemia should be considered. If drug- ... "New Drug Approvals". 2010-10-29. Retrieved 2010-11-08. "FDA approves Teflaro for treatment of bacterial infections". 30 Oct ...

*PTC Therapeutics

... the investigational drugs journal. 9 (11): 783-9. PMID 17096300. Bratulic, Anna (2009-09-02). "Roche, PTC Therapeutics to ... Hamed SA (2006). "Drug evaluation: PTC-124--a potential treatment of cystic fibrosis and Duchenne muscular dystrophy". IDrugs ... Since 2003, PTC has been working on a drug for Duchenne muscular dystrophy. In September 2009, PTC has entered into an ... Bain, Lisa J (2006). "Drug development in critical times". NeuroRX. 3 (4): 540-3. doi:10.1016/j.nurx.2006.08.004. PMC 3593415 ...

*HIV/AIDS in China

Expert Opinion on Investigational Drugs. 16 (9): 1355-1364. doi:10.1517/13543784.16.9.1355. PMID 17714022. Chen Sheng Li, Zhang ... 2006 World drug report. Geneva: United Nations Office on Drugs and Crime, 2006. National Drug Abuse Surveillance Center. Annual ... The most commonly used drug is heroin, which accounts for 85% of total reported drug use, although amphetamines are becoming ... For example, the government is working with neighboring countries to prevent drug smuggling, and is increasing anti-drug ...

*Ketoconazole

Expert Opinion on Investigational Drugs. 19 (2): 185-94. doi:10.1517/13543780903381411. PMID 20047506. Rossi, S, ed. (2013). ... FDA Drug Safety Communication. U.S. Food and Drug Administration. July 26, 2013. Retrieved November 23, 2013. Witjes FJ, ... Multidrug-resistance (MDR) genes can also play a role in reducing cellular levels of the drug. As azole antifungals all act at ... On July 2013, the U.S. Food and Drug Administration (FDA) issued a warning that taking ketoconazole orally can cause severe ...

*Diazepam

Expert Opinion on Investigational Drugs. 14 (5): 601-18. doi:10.1517/13543784.14.5.601. PMID 15926867. Dièye AM, Sylla M, ... Diazepam drug misuse can occur either through recreational misuse where the drug is taken to achieve a high or when the drug is ... The Misuse of Drugs Act 1971 makes it illegal to possess the drug without a prescription, and for such purposes it is ... Diazepam is a drug of potential abuse and can cause drug dependence. Urgent action by national governments has been recommended ...

*Dendreon

Nuvelo". Current Opinion in Investigational Drugs. 5 (3): 327-33. PMID 15083600. "Activated Cell Therapy Announces New ... New Jersey to accommodate production for a Phase III trial and possible 2007 drug approval by the U.S. Food and Drug ... Scher was the lead clinical trial investigator for a rival prostate cancer drug from the biotech company Novacea. Their ... Dendreon's stock value fell 66% on August 4, 2011, after abandoning its forecast for its debut drug Provenge. In November 2014 ...

*Indantadol

... the Investigational Drugs Journal. 10 (9): 636-44. PMID 17786847. "IN-STEP Phase IIb study results". "Vernalis initiates Pilot ... "CHF 3381". Drugs in R&D. 5 (1): 28-30. 2004. doi:10.2165/00126839-200405010-00005. PMID 14725488. Mattia C, Coluzzi F ( ... Indantadol (CHF-3381, V-3381) is a drug which was formerly being investigated as an anticonvulsant and neuroprotective and is ...

*Palovarotene

Current Opinion in Investigational Drugs. 10 (11): 1243-1250. PMID 19876792. Stolk, J; Stockley, RA; Stoel, BC; Cooper, BG; ... Palovarotene is being developed by Clementia Pharmaceuticals and was granted Fast Track and orphan drug designations by the ... United States Food and Drug Administration for the treatment of FOP and Orphan Medicinal Product Designation by the European ...

*Interleukin 6

Expert Opinion on Investigational Drugs. 6 (3): 237-66. doi:10.1517/13543784.6.3.237. PMID 15989626. Kristiansen OP, Mandrup- ... These and many other reports suggest that a clinical study of a neutralizing IL-6 biological or drug based antagonist is likely ... Kundakovic M, Chen Y, Guidotti A, Grayson DR (Feb 2009). "The reelin and GAD67 promoters are activated by epigenetic drugs that ... First IL-6-blocking drug nears approval for rare blood disorder, Nature Medicine, October 7, 2013 Korneev, KV; Atretkhany, KN; ...

*Temsirolimus

Rubio-Viqueira, B; Hidalgo, M (2006). "Targeting mTOR for cancer treatment". Current Opinion in Investigational Drugs. 7 (6): ... p. 2. ,access-date= requires ,url= (help) "FDA Approves New Drug for Advanced Kidney Cancer" (Press release). Food and Drug ... "Temsirolimus Monograph for Professionals". Drugs.com. Drugs.com. Retrieved 7 March 2015. Wan, Xiaolin; Shen, Na; Mendoza, ... Temsirolimus Drug Monograph. CCO Formulary - June 2014: Cancer Care Ontario. p. 4. ,access-date= requires ,url= (help). ...

*List of investigational anxiolytics

List of investigational drugs Garakani, Amir; Murrough, James W.; Iosifescu, Dan V. (2014). "Advances in Psychopharmacology for ... This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not ... Doggrell, S. A. (2007). Novel drugs and products in neuroscience. Drugs of the Future, 32(11), 1007-1017. https://journals. ...

*Surinabant

Expert Opinion on Investigational Drugs. 14 (3): 339-42. doi:10.1517/13543784.14.3.339. PMID 15833065. Lamota, L; Bermudez- ... It may also be developed as an anorectic drug to assist with weight loss, however there are already several CB1 antagonists or ... so surinabant is at present mainly being developed as an anti-smoking drug, with possible application in the treatment of other ...