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*  Short course immune induction therapy
... drugs which put the patients at risk of developing infection, cancer, and cardiovascular disease. Immune tolerance can be ... Immune tolerance is maintained by central and peripheral tolerance. During central tolerance, T-cells are selected in the ... These strategies employed the use of soluble peptide tolerance and oral peptide tolerance to great efficacy in experimental ... and timing of administration required to induce tolerance. While antigen-specific tolerance induction is an attractive strategy ...
*  Alcohol tolerance
Carroll, Charles R. Drugs in Modern Society . NY: McGraw-Hill, 2000 (fifth ed.). Chesher, G.; Greeley, J. (1992). "Tolerance to ... Not all differences in tolerance can be traced to biochemistry. Differences in tolerance levels are also influenced by socio- ... will have a higher alcohol tolerance. The alcohol tolerance is also connected with activity of alcohol dehydrogenases (a group ... Alcohol tolerance may lead to (or be a sign of) alcohol dependency. Heavy alcohol consumption over a period of years can lead ...
*  Drug tolerance
... is called drug desensitization. The opposite concept to drug tolerance is drug reverse tolerance (or drug sensitization), in ... further reducing the drug's effects. Drug tolerance is indicative of drug use but is not necessarily associated with drug ... Behavioral tolerance occurs with the use of certain psychoactive drugs, where tolerance to a behavioral effect of a drug, such ... Drug tolerance should not be confused with drug tolerability, which refers to the degree to which overt adverse effects of a ...
*  Ramp effect
Much of drug rehabilitation consists of resisting and reversing the ramping effect. Drug tolerance. ... The ramp effect (or ramping effect) is a phenomenon involved in drug addiction whereby an addict develops a resistance to a ...
*  Diflunisal
"The Diflunisal Trial: Study accrual and drug tolerance". Amyloid. 19 (S1): 37-38. doi:10.3109/13506129.2012.678509. Berk, JL; ... Diflunisal also has an antipyretic effect, but this is not a recommended use of the drug. It has been found to inhibit p300 and ... It is classed as a nonsteroidal anti-inflammatory drug (NSAID) and is available in 250 mg and 500 mg tablets. Like all NSAIDs, ... The long plasma half-life is a distinctive feature of diflunisal in comparison to similar drugs. To increase the rate at which ...
*  Amphetamine dependence
Tolerance is expected to develop with regular substituted amphetamine use. When substituted amphetamines are abused, drug ... "Amphetamines: Drug Use and Abuse". Merck Manual Home Health Handbook. Merck. Retrieved 26 September 2013. Chronic Amphetamine ... Amphetamine dependence refers to a state of psychological dependence on a drug in the amphetamine class. In individuals with ... "Efficacy of psychostimulant drugs for amphetamine abuse or dependence". Cochrane Database of Systematic Reviews. 9 (9): ...
*  Opium
Several pills of opium were smoked at a single session depending on the smoker's tolerance to the drug. The effects could last ... Regular use can lead to drug tolerance or physical dependence. Chronic opium addicts in 1906 China or modern-day Iran consume ... "Drug laws in Australia". Carstairs C. (2006). "Jailed for Possession: Illegal Drug Use, Regulation, and Power in Canada, 1920- ... In 2003, China was estimated to have four million regular drug users and one million registered drug addicts. There were no ...
*  Multidrug tolerance
2016) Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells. Mol Cell, 62: 284-294. Yaakov, G., Lerner ... Multidrug tolerance or antibiotic tolerance is the ability of a disease-causing microorganism to resist being killed by ... Microorganisms that display multidrug tolerance can be bacteria, fungi or parasites. Recognition of antibiotic tolerance dates ... Although tolerance is widely considered a passive state, there is evidence indicating it can be an energy-dependent process. ...
*  BufferGel
A similar trial in the United States also showed drug tolerance. Zeitlin, L.; Hoen, T. E.; Achilles, S. L.; Hegarty, T. A.; ... A phase I clinical trial done on women in India, Thailand gave supporting evidence that users tolerate the drug well. ... and pH were measured by vaginal colposcopy and rectal lavage researchers determined that it fit the safety profile of a drug ...
*  CREB
"CREB regulation of BK channel gene expression underlies rapid drug tolerance". Genes, Brain, and Behavior. 8 (4): 369-76. doi: ... CREB also has an important role in the development of drug addiction and even more so in psychological dependence. There are ...
*  Flupirtine
Drug tolerance does not develop in most cases, but has individually occurred. Flupirtine is a selective neuronal potassium ... Flupirtine Drugs.com. Accessed 30 August 2016 McMahon FG, Arndt WF, Newton JJ, Montgomery PA, Perhach JL (1987). "Clinical ... Flupirtine showed promise for fibromyalgia due to its different action than the three approved by U.S. FDA drugs: pregabalin, ... Szelenyi, I (March 2013). "Flupirtine, a re-discovered drug, revisited". Inflammation Research. 62 (3): 251-8. doi:10.1007/ ...
*  Ethionamide
Somner, A.R. (1959). "2-Ethylisothionicotinamide ('1314') in pulmonary tuberculosis: A controlled trial of drug tolerance". ... "Ethionamide Use During Pregnancy , Drugs.com". www.drugs.com. Archived from the original on 2016-12-21. Retrieved 2016-12-14. " ... The drug's labeling cautions against excessive alcohol ingestion as it may provoke a psychotic reaction. Ethionamide is a ... Resistance can emerge from mutations in ethA, which is needed to activate the drug, or ethR, which can be overexpressed to ...
*  Classical conditioning
This compensatory reaction may contribute to drug tolerance. If so, a drug user may increase the amount of drug consumed in ... For example, if a drug causes the body to become less sensitive to pain, the compensatory conditioned reaction may be one that ... For example, if the drug has always been administered in the same room, the stimuli provided by that room may produce a ... A stimulus that is present when a drug is administered or consumed may eventually evoke a conditioned physiological response ...
*  Exopolyphosphatase
"The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence". PLoS ONE. 6 (11 ...
*  Methamphetamine
In dependent users, withdrawal symptoms are positively correlated with the level of drug tolerance. Depression from ... "Methamphetamine". Drug profiles. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). 16 August 2010. Retrieved 1 ... Tolerance is expected to develop with regular methamphetamine use and, when used recreationally, this tolerance develops ... In Western Australia under the Misuse of Drugs Act 1981 4.0 g of methamphetamine is the amount of prohibited drugs determining ...
*  Dextroamphetamine
Drug tolerance develops rapidly in amphetamine abuse (i.e., a recreational amphetamine overdose), so periods of extended use ... "Drugs@FDA: FDA Approved Drug Products: Dexedrine". U.S. Food and Drug Administration. Retrieved 30 December 2015. DEXEDRINE ... The severity of overdose symptoms increases with dosage and decreases with drug tolerance to amphetamine. Tolerant individuals ... "Drugs@FDA: Dexedrine: Label and Approval History". U.S. Food and Drug Administration. Retrieved 30 December 2015. 08/02/1976 ...
*  Amphetamine
Drug tolerance develops rapidly in amphetamine abuse (i.e., a recreational amphetamine overdose), so periods of extended use ... "European drug report 2014: Trends and developments" (PDF). Lisbon, Portugal: European Monitoring Centre for Drugs and Drug ... "National Drug Code Amphetamine Search Results". National Drug Code Directory. United States Food and Drug Administration. ... In other nations, such as Canada (schedule I drug), the Netherlands (List I drug), the United States (schedule II drug), ...
*  Bretazenil
In a study in rats cross-tolerance between the benzodiazepine drug chlordiazepoxide and bretazenil has been demonstrated. In a ... Cross-tolerance has also been shown between bretazenil and full agonist benzodiazepines in rats. In rats tolerance is slower to ... 1993). "Aspects of benzodiazepine receptor structure and function with relevance to drug tolerance and dependence". Biochem Soc ... 1993). "Tolerance/cross-tolerance to the discriminative stimulus effects of chlordiazepoxide and bretazenil". Mol Chem ...
*  Opiorphin
"Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects" (PDF). J. Physiol. ... "Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects". J. Physiol. ... Popik P, Kamysz E, Kreczko J, Wróbel M (November 2010). "Human opiorphin: the lack of physiological dependence, tolerance to ... Curr Drug Targets. 9 (10): 887-94. doi:10.2174/138945008785909356. PMID 18855623. Davies KP (March 2009). "The role of ...
*  Lisdexamfetamine
Drug tolerance develops rapidly in amphetamine abuse (i.e., a recreational amphetamine overdose), so periods of extended use ... The severity of overdose symptoms increases with dosage and decreases with drug tolerance to amphetamine. Tolerant individuals ... Exercise has been proposed as a treatment for drug addiction that may reduce drug craving and risk of relapse. Although few ... compulsive drug-seeking) with further increases in its expression. While there are currently no effective drugs for treating ...
*  William Stewart Halsted
As revealed by Osler's diary, Halsted developed a high level of drug tolerance for morphine. He was "never able to be reduce ... Sigmund Freud, William Halsted, and the Miracle Drug Cocaine. Pantheon Books. p. 211. Imber G: Genius on the Edge: The Bizarre ... In the process, Halsted became addicted to the drug. His close friend Harvey Firestone recognized the gravity of the situation ... Brecher, Edward M.; and the Editors of Consumer Reports (1972). "Licit and Illicit Drugs, Chapter 5, 'Some eminent narcotics ...
*  Adderall
Drug tolerance develops rapidly in amphetamine abuse (i.e., a recreational amphetamine overdose), so periods of extended use ... "National Drug Code Amphetamine Search Results". National Drug Code Directory. United States Food and Drug Administration. ... The severity of overdose symptoms increases with dosage and decreases with drug tolerance to amphetamine. Tolerant individuals ... Exercise has been proposed as a treatment for drug addiction that may reduce drug craving and risk of relapse. Although few ...
*  Pain management
When opioids are used for prolonged periods drug tolerance, chemical dependency, diversion and addiction may occur. Clinical ... Drugs such as gabapentin have been widely prescribed for the off-label use of pain control. The list of side effects for these ... thereby slowing metabolism of the drug. In addition, orphenadrine, cyclobenzaprine, trazodone and other drugs with ... Other drugs are often used to help analgesics combat various types of pain, and parts of the overall pain experience, and are ...
*  Lyft
Zero-tolerance drug and alcohol policy. After a ride is completed, drivers and passengers are given the opportunity to rate ...
*  Ethinamate
Regular use leads to drug tolerance, and it is usually not effective for more than 7 days. Prolonged use can lead to dependency ...
*  Classical Anatolia
central government in rome was often far from civil and military commanders in the field, and local ambitions often dragged ... Slowly a movement for religious tolerance developed. Jewish legend describes Jewish dispersion from as early as the Book of ... Mithrodates then dragged his eastern neighbour Armenia into the fray, since Tigranes the Great (95-55 BC) was his son in law. ...
*  Robin Allshire
"Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast". Nat. ...